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New research indicates that individuals carrying the red‑hair allele have been evolutionary winners in Europe for more than 10,000 years. The study, led by Harvard scientists, examined DNA from nearly 16,000 ancient remains and over 6,000 living Europeans, providing robust proof that human biology continues to evolve long after farming began. Researchers identified 479 genetic variants that show clear signs of positive selection. Among these are genes linked to red hair and fair skin, as well as variants that affect susceptibility to coeliac disease, diabetes risk, baldness and rheumatoid arthritis. The authors suggest that the advantage of red hair may stem from its association with lighter skin, which enhances vitamin D synthesis in low‑sunlight environments—a crucial benefit for early European farmers. Prior to this work, only about 21 traits had been documented as having risen through natural selection, such as lactase persistence. The scarcity of earlier examples had led some to argue that directional selection was rare after modern humans left Africa. By leveraging an unprecedented volume of ancient genomic data and advanced computational methods, the team demonstrated that selection pressures intensified during the transition from hunter‑gatherer societies to agricultural ones, reshaping hundreds of genes across West Eurasia. "With these new techniques and the sheer scale of ancient DNA, we can now observe how selection sculpted our biology in near real‑time," said Dr. Ali Akbari, the study’s first author. Beyond vitamin D, the rise of certain disease‑related alleles poses intriguing puzzles. A mutation that heightens the risk of coeliac disease emerged around 4,000 years ago and has steadily increased, implying that carriers may have enjoyed other survival advantages despite the autoimmune threat. Similarly, the immune‑regulating gene TYK2, which markedly raises tuberculosis susceptibility, grew in frequency between 9,000 and 3,000 years ago before declining, hinting at a complex balance between pathogen defense and disease risk. The analysis also uncovered negative selection against genetic profiles that promote a high body‑fat percentage, supporting the classic “thrifty genes” hypothesis: traits advantageous for storing energy during scarce hunter‑gatherer periods became detrimental once agriculture ensured a steadier food supply. "This work lets us assign both place and time to the forces that have shaped us," noted Prof. David Reich, senior author and Harvard Medical School geneticist. While the findings are confined to West Eurasian populations, they raise broader questions about whether similar evolutionary dynamics occurred elsewhere. The full study appears in Nature.

Rebuilding opens on a bleak, charred horizon, introducing Dusty (Josh O’Connor), a Colorado rancher whose ancestral land has been reduced to ash by a recent wildfire. A bank official’s blunt refusal to extend a loan underscores the decade‑long bleak outlook for the barren property.Stripped of his home, Dusty relocates to a spartan, government‑funded trailer camp and takes a humbling highway‑maintenance job. The film deepens his personal stakes through interactions with his ex‑wife Ruby (Meghann Fahy), their ten‑year‑old daughter Callie‑Rose (Lily LaTorre), and his ailing mother‑in‑law Bess, portrayed by Oscar‑winner Amy Madigan. A poignant scene shows Dusty ferrying Callie‑Rose to the local library, where they share a shaky Wi‑Fi connection for her schoolwork.Amid the trailer community, Dusty forms a tentative bond with the resilient Mali (Kali Reis), hinting at a potential romance beyond mere friendship. Their collective moments around a campfire evoke the tone of Chloé Zhao’s Nomadland, positioning the film within a growing genre of American stories about displacement and survival.Notably, the narrative avoids direct references to climate change or governmental responsibility, presenting the wildfire as an isolated tragedy rather than a symptom of a broader environmental crisis. This omission mirrors a recurring pattern in U.S. cinema, where the focus remains on personal resilience rather than systemic solutions.O’Connor delivers a nuanced performance, channeling the restrained British sensibility of his earlier work into Dusty’s quiet strength and vulnerability. His portrayal anchors the film’s emotional core, while the supporting cast—particularly Madigan’s compassionate Bess and Reis’s tough‑yet‑tender Mali—adds depth to the community portrait.Rebuilding arrives in UK cinemas on 17 April, offering audiences a contemplative look at loss, renewal, and the fragile ties that bind families and strangers alike.

Budget airline easyJet has issued a profit warning, citing the impact of the Iran conflict on fuel prices and bookings. The airline has seen fuel costs rise by £25m in the last month alone, driven by the escalating tensions in the Middle East.EasyJet expects to report an increased pre-tax loss of £540-£560m for the six months to March, up from £394m in the first half of 2024-25. The carrier typically generates most of its revenue in the second half of the year, which includes the peak summer period.The airline has hedged 70% of its fuel needs for the rest of the financial year to September, but each $100 movement in the spot price of jet fuel per metric tonne adds £40m in costs for its unhedged supply. Currently, the price is about $800 higher than before the conflict started.Chief executive Kenton Jarvis said demand remained strong in the short term, but customers were leaving it later to book due to economic uncertainty. However, he assured that fuel supplies remained normal and that any talk of having to cancel flights was pure speculation.Jarvis added that there was continued positive demand, but easyJet's financial performance had worsened year on year, impacted by the conflict in the Middle East and the competitive environment in some markets. Shares fell 3% in early trading.

Europe is projected to run out of jet fuel in about six weeks, according to the head of the International Energy Agency, raising the spectre of widespread flight cancellations.Fatih Birol told the Associated Press that without a rapid restoration of oil shipments from the Middle East, airlines could soon be forced to drop routes, warning that “some flights from city A to city B might be cancelled as a result of lack of jet fuel.”The shortage stems from the US‑Israel war on Iran, which has snarled global energy markets since the initial strikes in late February. In retaliation, Iran has effectively sealed the Strait of Hormuz, a critical artery for Gulf oil exports.Although a two‑week ceasefire was recently brokered, negotiations to end the hostilities have stalled, leaving the supply disruption unresolved.Meanwhile, Brent crude futures are trading more than 30% above pre‑war levels, intensifying pressure on fuel prices and adding to political scrutiny in the United States.Jet‑fuel shipments that departed before the conflict have largely arrived in Europe, but the remaining reserves are rapidly being drawn down, leaving the continent vulnerable.Airports Council International Europe has warned EU energy and transport commissioners that the region could face fuel shortages within three weeks, echoing industry norms that typically maintain about six weeks of fuel on hand.Birol warned that the situation represents a “dire strait” with serious ramifications for the global economy, noting that prolonged disruption would exacerbate inflation and dampen growth worldwide.The anticipated fallout includes higher petrol, gas and electricity prices, with the impact expected to be uneven across different regions.Airlines are already scrapping marginally profitable routes, especially those without robust hedging strategies, and even carriers with hedged fuel costs may need to reconsider schedules.Despite the broader concerns, British low‑cost carrier easyJet asserted it has sufficient fuel visibility through mid‑May and does not anticipate supply‑related issues in the near term.

Brazil's Federal Police have launched an investigation into Flavio Bolsonaro, a right-wing presidential candidate, for allegedly issuing defamatory statements against his election rival, President Luiz Inacio Lula da Silva. The probe was ordered by the Supreme Court's Justice Alexandre de Moraes and relates to posts Bolsonaro published in January.In the posts, Bolsonaro responded to the news of Venezuelan President Nicolas Maduro's abduction by the US with insinuations linking Lula to crimes. He wrote that Lula will be exposed and predicted the collapse of the left-wing alliance known as the Sao Paulo Forum due to scandals including international drug and arms trafficking and money laundering.Brazil's penal code considers defamation a criminal offence, with prosecutors able to seek heightened penalties for defamation against presidents or heads of state. The Federal Police have 60 days to carry out their initial investigation.The development comes as Bolsonaro and Lula are in a neck-and-neck race for the presidency ahead of October's general election. A recent poll showed Lula slightly ahead in the first round with 37% of the vote compared to Bolsonaro's 32%, but Bolsonaro polls slightly ahead in a one-on-one contest.Flavio Bolsonaro, a senator for Rio de Janeiro and the eldest son of former President Jair Bolsonaro, entered the 2026 presidential race with his father's endorsement. He has suggested that seeking his father's freedom would be part of his campaign.

A Pakistani delegation headed by Army Chief General Asim Munir arrived in Tehran on Wednesday, bearing a fresh message from Washington and urging the launch of a second round of negotiations between the United States and Iran. The effort comes as the two‑week ceasefire that halted hostilities last week is set to expire on April 22, leaving a narrow window to end a war that has claimed more than 4,000 lives across the Middle East, primarily in Iran and Lebanon. The initial round of talks, held in Islamabad on April 11‑12, marked the most significant direct engagement between Washington and Tehran in decades. Mediated by Pakistan, the sessions lasted over 20 hours and featured both indirect and direct exchanges between U.S. Vice President JD Vance and senior Iranian officials led by Parliament Speaker Mohammad Bagher Ghalibaf. Despite covering core issues—nuclear programme, sanctions relief, frozen assets and control of the Strait of Hormuz—the talks concluded without a memorandum, with Vance asserting that Iran “did not accept our terms” and that the U.S. requires a “fundamental commitment” to forego nuclear weapons. President Donald Trump has described the conflict as “very close to being over” and hinted that a second round could resume within days, possibly in Islamabad. However, Pakistan’s Prime Minister Shehbaz Sharif is currently on a four‑day tour of Saudi Arabia, Qatar and Turkey to rally regional backing, making a rapid return to Islamabad uncertain. U.S. officials have offered an “in‑principle” agreement to extend the ceasefire, yet a Reuters‑cited source confirmed that Washington has not formally committed to an extension. Meanwhile, Turkish President Recep Tayyip Erdogan expressed optimism, stating that “there can be no negotiating with clenched fists.” Key sticking points remain: Nuclear programme: The United States and Israel demand a complete halt to uranium enrichment, accusing Iran of weaponization despite a lack of public evidence. Iran maintains its enrichment is for civilian use and cites its obligations under the 1970 Non‑Proliferation Treaty. Strait of Hormuz: One‑fifth of global oil and LNG passes through this chokepoint. Since the February strikes, shipping through the strait has dropped by 95 %. Iran permits passage for “non‑hostile” vessels and seeks the right to levy tolls, while the U.S. insists on unrestricted navigation. Lebanon/Hezbollah: Iran demands that Israel cease its offensive against Hezbollah. While Tehran claims the ceasefire covers Lebanon, both the United States and Israel reject this, and Israel continues attacks on Hezbollah positions. Complicating the diplomatic landscape, President Trump announced a naval blockade of Iranian ports, adding pressure on Tehran and potentially hindering any imminent talks. With the ceasefire deadline looming and regional actors issuing mixed signals, the prospects for a renewed U.S.–Iran dialogue hinge on whether Pakistan can secure a consensus among the parties before the window closes.

Sudan, one of the world's most impoverished countries, has been ravaged by a civil war that began in 2023. The conflict, driven by a power struggle between the army and the paramilitary Rapid Support Forces (RSF), has left the nation unrecognizable. Over 40,000 people have been killed, and about 14 million – a quarter of the population – have been forced to flee their homes. Civilian infrastructure across the country has been extensively damaged.“We are not just facing a crisis – we are witnessing the systematic erosion of a country’s future,” Luca Renda, the United Nations Development Programme’s (UNDP’s) resident representative in Sudan, told Al Jazeera. A report by the UNDP and the Institute for Security Studies highlights the scale of Sudan’s economic collapse. Even under the most optimistic scenario of peace being achieved in 2026, Sudan would still lose an estimated $18.8 billion in gross domestic product (GDP) by 2043.The war has had a devastating impact on Sudan's infrastructure and basic services. $6.4 billion was lost in GDP in 2023 alone, reflecting a simultaneous collapse across all major parts of Sudan’s economy. The destruction of infrastructure has triggered displacement and made it difficult for people to secure adequate housing or access basic services. Up to 40 percent of power generation capacity has been lost, and key water infrastructure has been destroyed or seized, cutting communities off from clean water and sanitation.The labor market has also been severely affected, with agriculture – once the backbone of Sudan’s economy – severely hit. Cultivated land has shrunk, adversely impacting rural livelihoods. Average incomes have fallen back to levels last seen in 1992. About 90 percent of manufacturing activity has been destroyed in key economic hubs, eliminating thousands of jobs.The oil industry has suffered significantly, with oil output falling amid widespread instability and infrastructure damage. The Khartoum refinery, which previously processed up to 100,000 barrels per day, has been out of operation since July 2023. Key infrastructure, including pipeline routes carrying crude to Port Sudan, has been hit.The collapse of the Sudanese pound and supply chains has caused a sharp rise in living costs. Food prices have surged, with four pieces of bread now costing about 1,000 pounds, an amount that had previously bought six pieces. Wages have failed to catch up with inflation, leaving many households without access to necessities. Nearly half the population is now experiencing acute food shortages.The economic collapse has had a profound impact on Sudan's people, with 34 million people in need of assistance and 19 million facing acute food shortages. The war has caused death, trauma, and profound loss, casting a long shadow over Sudan’s future and dimming the prospects of a generation whose lives are being shaped by violence. If the conflict continues to 2030, Sudan’s economy in 2043 would be about $34.5 billion smaller than it would have been without the war, and GDP per capita would drop by roughly $1,700.

The United States is set to move **over 10,000 additional service members** into the Middle East before the end of April, according to officials speaking anonymously to The Washington Post. The reinforcement is intended to heighten pressure on Iran while the current cease‑fire, declared a week ago, remains in force until April 22. Approximately 6,000 troops will embark aboard the USS George H.W. Bush carrier and its escort vessels, which are transiting around Africa to join the existing carrier presence. An additional 4,200 personnel from the Boxer Amphibious Ready Group and the 11th Marine Expeditionary Unit are expected to arrive later in the month. These deployments bring the total number of U.S. forces engaged in the conflict since its start on February 28 to roughly 50,000 troops. With the arrival of the George H.W. Bush, the region will host three U.S. carriers: the newly arrived vessel, the USS Abraham Lincoln, and the USS Gerald Ford, all of which have already taken part in combat operations against Iran. Concurrently, U.S. Central Command (CENTCOM) announced on social media that its naval blockade of Iranian maritime trade is "fully implemented" and that American forces have "completely halted economic trade" to and from Iran by sea. However, maritime‑tracking data released on Tuesday showed several ships departing Iranian ports and navigating the Strait of Hormuz, suggesting the blockade’s effectiveness may be limited. Amid the military buildup, diplomatic channels remain active. President Donald Trump told The New York Post that a new round of negotiations with Iran could be convened in Pakistan within two days, following a marathon session in Islamabad that ended without a breakthrough. The previous high‑stakes talks failed to secure a lasting peace agreement, and the cease‑fire is slated to expire on April 22. According to the Washington Post sources, the fresh troop influx is designed to give the U.S. administration leverage in ongoing talks while preserving the option for "additional strikes or ground operations" if negotiations falter. This dual strategy underscores Washington’s intent to maintain both diplomatic and kinetic pressure on Tehran as the regional conflict evolves.

In the midst of Israel's ongoing attacks on Lebanon, which have resulted in the displacement of at least one million people, migrant workers are taking initiative to support their communities. Myra Aragon, a Filipino migrant, runs a community center called Tres Marias in a Beirut suburb, providing meals to around 200 people daily, mostly migrant workers.Aragon's efforts are part of a larger trend of migrant solidarity in Lebanon. With many migrant workers facing restrictions and discrimination due to the country's kafala labor system, they are organizing themselves to help those in need. Tres Marias is one of at least three food kitchens run by migrant workers in Lebanon, serving not only migrants but also occasionally Lebanese families.The war has exacerbated existing challenges for migrant workers, with many facing displacement, discrimination, and limited access to shelters. However, Aragon and others like her are working to provide food and a sense of community to those affected. As Aragon notes, 'Food is unifying... It is a way for people to learn about food from the Philippines, and it makes people feel cared for and seen.'Despite the danger and uncertainty posed by the war, Aragon remains committed to her work, stating, 'This war is a lot worse than the last one... But as the war carries on, I will continue to cook and distribute food to those who need it.'