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Residents of Sidon are recalling the traumatic experience of Israeli airstrikes that targeted their area, following a recent ceasefire agreement between Israel and Iran. The strikes had caused significant fear and destruction, leaving a lasting impact on the local community. The ceasefire has brought a sense of relief, but the memories of the intense violence and fear for their safety continue to linger among the residents. The incident has underscored the fragile nature of peace in the region and the ongoing tensions between Israel and Iran.

Pakistan's capital, Islamabad, is preparing to host critical talks between US and Iranian officials this weekend, in a bid to revive a faltering ceasefire and bring an end to the devastating conflict in the Middle East.The negotiations, scheduled to begin on Saturday, will be led by US Vice President JD Vance and Iranian Parliament Speaker Mohammad Bagher Ghalibaf, with Pakistani officials facilitating the discussions.The talks are taking place against a backdrop of escalating tensions in the region, with Israel's intensified bombing of Lebanon and Iran's attacks on its Gulf neighbors. A two-week ceasefire was agreed upon by both Washington and Tehran, facilitated by Pakistan, but it is already under strain.Key issues on the agenda include Iran's 10-point proposal for peace, which calls for Iranian oversight of the Strait of Hormuz, the withdrawal of US combat forces from the Middle East, and a halt to military operations against allied armed groups. The US has not formally accepted these terms, but President Trump has described the plan as 'workable'.One of the major obstacles to a lasting settlement is Israel's continued aggression in Lebanon, which has resulted in over 200 deaths. Iran has warned that it may abandon the ceasefire if Israeli strikes continue, while the US has insisted that the ceasefire terms do not cover Lebanon.Despite the challenges, analysts believe that a modicum of agreement between the US and Iran on key issues, such as the nuclear issue and the Strait of Hormuz, may be possible. However, Israel's absence from the talks is seen as a significant structural challenge to a lasting settlement.

The global energy crisis has been labeled 'the mother of all crises' by Turkish Energy Minister Alparslan Bayraktar, as tensions in the Strait of Hormuz continue to escalate. The crisis, sparked by Iran's retaliatory blocking of the strait, has significant implications for global energy supplies and security.Bayraktar, in an exclusive interview with Al Jazeera Arabic, highlighted the importance of diversifying energy routes to mitigate the impact of such crises. He noted that Turkey, with its strategic location between Asia and Europe, has become a pivotal country in the region, hosting key pipelines such as the 'Blue Stream' and 'TurkStream'.The minister emphasized that Turkey is well-suited to weather the crisis, with sufficient strategic energy reserves, including gas storage facilities that are 72 percent full, compared to Europe's 28 percent. However, he warned that rising oil and gas prices still burden the state budget, with an increase of $1 per barrel costing Ankara approximately $400 million.Bayraktar also discussed the potential for a new energy architecture to emerge, driven by the need for diversification. He proposed several projects, including the transportation of Turkmen gas across the Caspian Sea to Turkey and Europe, extending the Iraq-Turkey oil pipeline to reach Basra, and constructing a natural gas pipeline from Qatar to Turkey.The crisis has significant economic implications, with oil prices potentially rising to $200 per barrel in a worst-case scenario, which could lead to another global recession. Bayraktar stressed the importance of a lasting peace in the region to stabilize energy markets and prevent further economic damage.

The fragile peace between the US and Iran is heavily contingent upon Israel's actions, with growing international calls for restraint to prevent escalation in the region. As tensions simmer, the delicate balance of power in the Middle East hangs in the balance, with Israel's moves being closely watched by global powers. Any provocative actions by Israel could potentially derail the ceasefire, plunging the region into renewed conflict and instability. International observers stress the need for calm and measured responses from all parties involved to ensure a lasting peace.

The conflict in Gaza has resulted in a significant number of amputations, with over 6,000 adults and children undergoing amputations since October 2023, according to the WHO and Palestinian Ministry of Health. Ola Jamal, 36, is one of the many Palestinians who have been forced to flee Gaza due to the conflict. She was breastfeeding her two-month-old son, Zain, when a missile struck al-Nasr hospital in Gaza, causing her to lose her arm. Jamal and her family were forced to separate, with her children being cared for by another family. This traumatic experience has had a lasting impact on Jamal and her children, with her son Zain still experiencing nightmares and trauma two years after the event. Shadi Sharif Ayesh al-Sous, a father of two, lost his leg in a missile strike while collecting firewood. He had his leg amputated above the knee and now waits to return home to Gaza. However, many Palestinians in Egypt face significant challenges, including restricted access to healthcare and prosthetic care due to their uncertain legal status. Yousef El Deeb, a certified prosthetist at Orthomedics in Cairo, says his clinic has treated about 300 Palestinian patients since October 2023, mostly through the support of NGOs. However, the lack of documentation and uncertain legal status of Palestinians in Egypt makes it difficult for them to access long-term prosthetic care without the support of NGOs. The situation for Palestinians in Egypt is further complicated by their lack of formal residency or refugee status. Without valid residency permits, survivors are often restricted to hostels or share a flat with other families, unable to work and living under the constant pressure of temporary status. This lack of documentation makes accessing hi-tech, long-term prosthetic care almost impossible without the support of NGOs.

Britain has weathered a succession of crises since the 2008 financial collapse— austerity, Brexit, Covid, the Ukraine war and recent political turbulence. Prime Minister Keir Starmer says the war in Iran must become a turning point, forcing the country to build lasting resilience at home and with its European partners.Starmer stresses that the UK’s response to the Iranian aggression has been guided by de‑escalation, diplomacy and the swift reopening of the Strait of Hormuz. While Britain avoided direct offensive action, it intercepted drones, shot down missiles and protected British lives and interests alongside allies who share the same stance.The government’s approach, he explains, is to reduce escalation, work with allies and safeguard economic stability. In a world that is “more volatile and dangerous than at any other point in my lifetime,” such a strategy is presented as essential for protecting British interests.Starmer links global instability to domestic pressures, noting that the same tensions that threaten security also drive up energy prices, disrupt supply chains and strain household finances. To counter this, his administration has capped energy bills and invested heavily in homegrown energy sources, aiming to free the UK from reliance on external gas suppliers.On the defence front, the UK has announced the largest sustained increase in defence spending since the Cold War, reinforcing European alliances and expanding military capacity. Parallel to these security measures, the government has launched an ambitious industrial strategy, strengthened workers’ rights and pledged to lift more than half a million children out of poverty through a new child‑poverty programme.Starmer argues that these policies are not isolated reactions but part of a broader shift toward long‑term resilience. By building secure, domestic energy, robust alliances and a stable economy, Britain can “shape its future and deliver on priorities that matter to working people.”He concludes that Britain will not attempt to recreate the pre‑2008 world; instead, it will forge a stronger, more secure, and more resilient nation capable of withstanding future shocks.

In a stark address delivered as the cease‑fire in the Iran conflict teetered, IMF Managing Director Kristalina Georgieva warned that the war will leave a permanent scar on the global economy, slowing growth beyond the IMF’s original projections for 2026. Georgieva noted that, had the hostilities not erupted six weeks ago, the Fund would have been poised to raise its 2026 growth outlook. Instead, even the most optimistic scenario now entails a downgrade, and a swift return to pre‑war conditions appears unlikely. The uncertainty surrounding the cease‑fire—exacerbated by divergent positions of Washington and Tehran—has already pushed oil prices higher, reflecting fears of continued disruptions to shipments through the Strait of Hormuz, a vital conduit for world energy supplies. According to the IMF’s upcoming World Economic Outlook, the conflict’s “scarring effects” will translate into lower living standards worldwide. The Fund had previously forecast global growth of 3.1% in 2026, a modest slowdown from 3.2% in 2025, buoyed by a tech‑driven investment surge. Georgieva emphasized that the war arrived when the economy was riding “considerable momentum” from technology investment and supportive financial markets. She outlined the mechanisms of damage: damaged infrastructure, supply‑chain interruptions, eroded confidence, and prolonged uncertainty over oil and gas production in the region. These factors will depress growth regardless of whether a peace agreement is ultimately reached. Georgieva highlighted that the most vulnerable will be net oil‑importing nations, poorer economies and small island states, which stand to feel the brunt of higher energy costs and reduced trade flows. She urged governments to avoid unilateral measures such as export bans or price controls, warning that such actions could "pour gasoline on the fire" and further destabilise markets. With many countries already carrying elevated debt levels and higher borrowing costs, the IMF chief called for targeted, temporary assistance to protect the most at‑risk households. She cautioned against broad tax cuts or blanket energy subsidies, which could stoke inflation and strain fragile public finances. Central banks, she added, should keep policy rates steady while remaining ready to act against inflationary pressures. Bank of England Governor Andrew Bailey, who also chairs the Financial Stability Board, echoed the IMF’s concerns, describing the conflict as a "very big shock" that has heightened market volatility. He stressed that the situation remains fluid and that policymakers must stay vigilant. Overall, the IMF’s message is clear: the Iran war will reshape the global growth trajectory for the foreseeable future, and coordinated, prudent policy responses are essential to mitigate its lasting impact.

On All Hallows' Eve in 1517, Martin Luther, a 33-year-old German priest and scholar, took a pivotal step that would change the course of history. He marched up to the church in Wittenberg and nailed a document to the door, containing 95 statements, or theses, protesting against corruption in the church.Luther's actions led to his excommunication and a dramatic escape, but they also marked the beginning of the Reformation. As a musician himself, Luther knew the power of music in spreading his new doctrine. He saw music as a divine gift 'next to theology' and used it to incite people to do good and to teach them.Luther's hymns, known as chorales in the German-speaking world, were simple, memorable tunes, often adapted from popular melodies, repeated verse to verse. The words were in everyday German, and the hymn tunes were harmonized with simple, block chords, making it possible for anyone to sing along.One of Luther's most famous hymns, Ein feste Burg ist unser Gott (A Safe Stronghold Our God is Still), is still sung today in churches around the world. His hymns were widely distributed using the relatively new technology of the movable type printing press, invented by Johannes Gutenberg.Luther's musical legacy continued to influence composers, including Heinrich Schütz and Johann Sebastian Bach, who composed new chorales and clothed existing ones in rich harmonies. Bach's chorale preludes, where an elaborate melodic line unfolds until the chorale tune emerges, remain iconic.The chorales have also had a lasting impact on popular music, with arrangements by artists like the Swingle Singers and Myra Hess, and even influencing 1970s pop music, such as Apollo's 'Joy' and The Beach Boys' 'Lady Lynda'.

A 47‑year‑old woman who had endured three life‑threatening autoimmune diseases for more than a decade is now living a near‑normal life after an experimental CAR‑T cell therapy reset her immune system at University Hospital Erlangen in Germany.Before the procedure she had exhausted nine different treatments with no lasting benefit, relying on daily blood transfusions and continuous anticoagulation to manage her illnesses.Within weeks of the infusion, doctors observed rapid improvement in all three conditions—a world‑first outcome. She has remained in treatment‑free remission for 14 months and has largely returned to everyday activities.Prof Fabian Müller, who led the team, called the speed and depth of the response “remarkable” and said the therapy “significantly improved her quality of life.” He emphasized that clinical trials are required to determine how durable the effect is and whether it can help other autoimmune patients.The patient suffered from three distinct disorders: autoimmune haemolytic anaemia (AIHA), where rogue immune cells destroy red blood cells; immune thrombocytopenia (ITP), which depletes platelets and raises bleeding risk; and antiphospholipid syndrome (APS), which promotes dangerous blood clots. All three stem from malfunctioning B‑cells.With no conventional options left, doctors turned to CAR‑T therapy, a technique that has revolutionised treatment for certain cancers. They harvested her white‑blood cells, isolated the T‑cells, engineered them to recognise the CD19 protein on B‑cells, and reinfused the modified cells.The engineered T‑cells swiftly eliminated the pathogenic B‑cells. She received her last blood transfusion a week after treatment and was able to perform routine tasks within two weeks. Follow‑up tests showed a reconstituted, healthy B‑cell population, suggesting an immune reset. The findings were published in the journal Med.She still exhibits a mildly low white‑cell count and slightly elevated liver enzymes, which researchers attribute to the cumulative impact of prior therapies rather than the CAR‑T product.Rheumatology expert Prof Ben Parker of Manchester University NHS Foundation Trust described the case as encouraging, noting that “the prolonged response off normal therapy suggests there has been an immune reset.” However, he warned that case reports alone cannot confirm efficacy and highlighted ongoing trials for lupus, myositis, multiple sclerosis, systemic sclerosis, vasculitis, and other autoimmune conditions.