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As rising temperatures push snakes and humans into closer contact, the world faces an estimated 5.5 million snakebites each year, resulting in 138,000 deaths and 400,000 lasting disabilities. In response, a Wisconsin‑based amateur scientist has taken an extreme route to help solve the crisis.For almost 20 years, Tim Friede, a former window cleaner, allowed some of the planet’s most lethal snakes to bite him, accumulating over 200 intentional bites. His goal: to provoke his own immune system into producing antibodies that could be harvested for a near‑universal antivenom.The endeavor has been perilous. Friede survived a coma after being bitten by two cobras within an hour, endured anaphylactic shocks, lost tissue in a finger, and even had to cut necrotic muscle from his leg. Yet he persisted, eventually becoming immune to the inland taipan—the world’s most venomous snake, whose single bite can kill more than 100 people.In 2019, California biotech firm Centivax hired Friede to extract his antibodies. Early laboratory work showed that his serum can neutralise toxins from 19 elapid species, including cobras, mambas, taipans, coral snakes and kraits—roughly half of all venomous snakes worldwide.The next step is a veterinary trial in Australia, slated for later this year, before any human application. If successful, the antivenom could dramatically reduce the burden of snakebite in low‑income regions across Asia and Africa, where most victims live.Climate scientists warn that warming climates will expand snake habitats and increase human exposure, as illustrated by the recent surge of rattlesnake bites in California’s Ventura County. This amplifies the urgency for scalable, affordable antivenoms, especially as international aid budgets face cuts and manufacturing capacity remains insufficient.Friede’s unconventional path underscores a broader lesson: confronting emerging health threats may require bold, unconventional science, but the potential payoff—a life‑saving treatment for millions—could be transformative.

On 23 June 2016, the United Kingdom’s electorate shifted from party‑centric voting to a binary choice between staying in or leaving the European Union. A decade later, about 60 % of the population still define themselves by the side they chose in that single referendum, turning a one‑off political decision into a lasting personal identity.While analysts often focus on the policy fallout—economic turbulence, party infighting, and shifting trade relations—the real impact runs deeper. The referendum ignited a civil‑war‑like split that continues to shape elections, media narratives, and everyday conversations across the country.Before the global upheavals of the George Floyd protests and the Covid‑19 vaccine rollout, Brexit was Britain’s most potent form of identity politics. It spawned new media outlets, such as GB News, and programmes like The Rest Is Politics, while also marginalising older cultural tropes like the “centrist dad” or “gammon” heckler on Question Time. Figures such as Nigel Farage and Zack Polanski now occupy the political fringe rather than the mainstream.The analysis draws on the new book Tribal Politics: How Brexit Divided Britain by political scientists Sara Hobolt and James Tilley. Their longitudinal surveys reveal a simple yet striking pattern: the referendum transformed a previously lukewarm public attitude toward the EU into a powerful, identity‑based habit.Prior to 2016, most Britons held only a mild Euroscepticism and gave the EU little thought. Even former Prime Minister David Cameron tried to silence the issue in 2006, believing it failed to engage voters. The sudden elevation of a niche concern to a national obsession forced ordinary citizens to pick a side, discuss it in pubs, and embed it into their self‑image—a process James Clear describes as building “identity‑based habits”.Data from Hobolt and Tilley show that emotional attachment to the Brexit identity was modest before the vote, rose sharply as the referendum approached, and surged dramatically after the result was announced. The post‑vote period saw a flood of EU‑themed merchandise, street rallies, and even flag‑clashes at cultural events such as the 2017 Last Night of the Proms.Crucially, the tribal divide has not faded. By 2025, only around 40 % of “Leavers” feel comfortable discussing politics with “Remainers”, and the sentiment is reciprocated. This goes beyond mere disagreement; it reflects a level of social discrimination where individuals on opposite sides would hesitate to share a home or marry into each other’s families.The authors note that the split now extends to perceptions of reality itself. Even in 2024, Remainers and Leavers disagreed on basic economic indicators, illustrating how the referendum reshaped not just policy preferences but fundamental worldviews.Class‑based voting, which dominated the 20th‑century British political landscape, has been largely supplanted by this new cultural cleavage. A previous study co‑authored by Tilley showed that the Labour Party’s turn toward the political centre in the 1990s eroded traditional working‑class loyalty. Today, leader Keir Starmer’s working‑class credentials appear largely symbolic, offering little substantive change.With class politics receded, culture wars have taken centre stage. The Brexit campaign’s vague promises about trade left the nation with a protracted, messy adjustment period. Immigration, famously dubbed the “baseball bat” issue by Dominic Cummings, remains the most polarising policy divide, followed by foreign aid and even the death penalty.Hobolt and Tilley’s most striking chart shows that while Remainers and Leavers clash over immigration, they share little disagreement on economic equality, workers’ rights, or public ownership—issues that directly affect household incomes. This suggests that the political battle is driven more by symbolic identity than by material concerns, benefitting those already financially secure.In sum, the United Kingdom’s post‑Brexit reality is one of entrenched tribalism, where a single referendum has reshaped social bonds, political discourse, and perceptions of truth itself. The nation continues to grapple with the legacy of a vote that turned a policy decision into a lasting cultural fault line.

In a recent statement, Janet Vance warned that a ceasefire with Iran can only be realized if the parties engage in good‑faith talks. She emphasized that mutual trust and sincere negotiation are essential for any lasting pause in hostilities, highlighting the delicate nature of the diplomatic process.

US Defense Secretary Pete Hegseth announced on Wednesday that the United States had achieved a "decisive" military victory over Iran, claiming the Iranian missile programme has been "functionally destroyed." Speaking alongside General Dan Caine, chairman of the Joint Chiefs of Staff, Hegseth described the operation—codenamed Operation Epic Fury—as a "historic and overwhelming" triumph that met every objective, including the dismantling of Iran’s navy, air‑defence systems and missile‑production capability. The declaration came a day after President Donald Trump stepped back from a threatened full‑scale assault on Iran, just two hours before a self‑imposed deadline for Tehran to reopen the blockaded Strait of Hormuz. The resulting cease‑fire agreement stipulates that Iran will not possess a nuclear weapon and that the United States will monitor the country’s enriched uranium stockpiles. While Hegseth emphasized that "they can still shoot here and there, but that would be very unwise," he also warned that US forces will remain in the region to ensure compliance with the two‑week cease‑fire and to oversee the safe transit of vessels through the strategic waterway. Iran’s response was equally emphatic. The Supreme National Security Council, cited by IRNA, congratulated the Iranian people on a "victory" and urged perseverance until the details of that victory are finalized. The council highlighted Iran’s alliances with the so‑called "axis of resistance" in Lebanon, Iraq, Yemen and occupied Palestine, claiming the coalition has delivered blows to the enemy over the past 40 days. At the same briefing, General Caine confirmed that US military objectives in Iran have been met, but framed the cease‑fire as a "pause" rather than a permanent end to hostilities, noting that forces remain ready to resume combat if necessary. In parallel diplomatic developments, a senior Iranian official told Reuters that Tehran could reopen the Strait of Hormuz on Thursday or Friday, contingent on a cease‑fire framework being reached ahead of a scheduled US‑Iran meeting in Pakistan. The closure of the strait has previously disrupted global oil and gas markets, making its reopening a critical economic signal. Trita Parsi, vice‑president of the Quincy Institute for Responsible Statecraft, told Al Jazeera that President Trump needed an exit from a war he described as "an absolute disaster" and that the next two weeks are "crucial" for any genuine diplomatic opening, though he cautioned that the situation is not yet resolved. Analysts note that the cease‑fire’s success will hinge on Iran’s willingness to allow unfettered navigation through the Strait of Hormuz and on US verification of Iran’s uranium holdings. The coming fortnight will test whether the declared victory translates into lasting stability in a volatile region.

Iran and the United States announced a two‑week ceasefire that will also guarantee safe navigation through the strategically vital Strait of Hormuz, a chokepoint through which roughly 20% of the world’s oil supply moves.The pause comes as the conflict entered its 40th day, with hopes now fixed on a diplomatic breakthrough during talks scheduled to begin in Pakistan on Friday.President Donald Trump declared that the truce would be activated once Tehran fully reopened the waterway, linking the cessation of hostilities to the restoration of a critical global supply route.Celebrations erupted across Iran, and numerous world leaders publicly welcomed the development, describing it as a step toward broader regional stability.The fighting, which has drawn in virtually the entire Middle East, saw Iran claim to target U.S. assets in several Gulf Cooperation Council (GCC) states, while Gulf nations accused Tehran of striking civilian infrastructure.Hezbollah’s March 2 attacks on Israel pulled Lebanon into the war, and although Israel has signaled support for the ceasefire, it warned that the agreement does not extend to Lebanon.Against this backdrop, Gulf and neighboring states have issued statements outlining their positions on the ceasefire:Saudi Arabia welcomed the truce, urging an immediate end to regional attacks and calling for the Strait of Hormuz to be reopened, emphasizing that the ceasefire should lead to a “comprehensive sustainable pacification.”Qatar described the ceasefire as an “initial step toward de‑escalation,” stressing the need for rapid implementation, full adherence by Iran, and the protection of maritime security and international trade under international law.United Arab Emirates diplomatic adviser Anwar Gargash hailed the outcome as a victory for a war the UAE sought to avoid, claiming the nation now possesses greater leverage and capacity to shape regional affairs.Oman expressed appreciation for Pakistan’s mediation and called for intensified efforts to address the root causes of the conflict, aiming for a permanent end to hostilities.Iraq welcomed the ceasefire but urged the United States and Iran to launch “serious and sustainable dialogue” that tackles underlying disputes and rebuilds mutual trust.Egypt framed the truce as a crucial opportunity for negotiations, diplomacy, and dialogue, insisting that any lasting peace must respect freedom of navigation and consider the legitimate security concerns of Gulf states.Turkey supported the ceasefire and pledged backing for the upcoming Islamabad talks, emphasizing the importance of full ground‑level implementation and strict adherence by all parties.Sudan called the two‑week pause a “positive step toward de‑escalation,” highlighting its potential to foster diplomacy and regional stability.

The United States and Iran have agreed to a two-week ceasefire, with talks to finalize a peace deal set to begin in Pakistan's Islamabad on Friday. The truce, announced by US President Donald Trump, will see Iran reopen the Strait of Hormuz, a vital maritime corridor through which a fifth of the world's oil supply passes.Countries around the world have welcomed the development, with many urging a lasting peace in the region. Israel's Prime Minister Benjamin Netanyahu supported Trump's decision, while also noting that the ceasefire does not include Lebanon, where Israeli forces have launched a ground invasion and are fighting with the Iran-aligned Hezbollah.Iraq's Ministry of Foreign Affairs welcomed the news of the ceasefire but stressed the need for full commitment to the deal to achieve a lasting resolution. Egypt's Ministry of Foreign Affairs said the ceasefire represents a very important opportunity for negotiations, diplomacy, and constructive dialogue.The United Nations Secretary-General Antonio Guterres welcomed the announcement and called on all parties to abide by the terms of the ceasefire. Japan's Chief Cabinet Secretary Minoru Kihara said Tokyo welcomes the news of a two-week ceasefire between the US and Iran as a positive move.Indonesia's Foreign Ministry called on Iran and the US to respect the sovereignty, territorial integrity, and diplomacy of each side. Malaysia's Ministry of Foreign Affairs said the ceasefire marks a significant development and serves as a crucial step towards de-escalating tensions and restoring peace and stability to the Middle East.Australia's Prime Minister Anthony Albanese and Minister for Foreign Affairs Penny Wong issued a joint statement welcoming the news and expressing their hopes that the deal will lead to a long-lasting resolution. New Zealand's Minister of Foreign Affairs Winston Peters said his government welcomes the news of a ceasefire, although many concerns remain.

After Tehran announced a two‑week ceasefire in the Iran war, financial markets breathed a noticeable sigh of relief. Oil prices tumbled by more than 10% on Wednesday, stock indices rallied, and optimism about the global economic outlook resurfaced. However, the reprieve is far from complete.For six weeks the world’s economy has been under pressure as Iran effectively closed the Strait of Hormuz, a chokepoint that handles roughly one‑fifth of global oil and gas shipments. The closure sparked what analysts have called the worst energy crisis of the modern era, driving oil to historic highs.Any progress toward re‑opening Hormuz would ease fears of a supply crunch that could otherwise trigger a cascade of recession risks. Yet the situation remains volatile: Tehran and Washington continue to send mixed signals about the waterway’s status, and Israel’s ongoing strikes in Lebanon add further uncertainty.Consumers already feel the strain. Despite the recent price dip, Brent crude remains above $90 a barrel, a sharp contrast to the sub‑$73 levels recorded before the conflict began. While this is an improvement from the period when prices hovered above $100, it still represents a significant premium over pre‑war benchmarks.Most economists expect oil to stay above its pre‑war price throughout 2026. In its baseline forecast, consultancy Capital Economics projects Brent to settle around $80 per barrel by year‑end. Under that scenario, headline inflation in the United States and Europe would hover between 3% and 4% year‑on‑year, while GDP growth is likely to decelerate across major economies.The lingering uncertainty is amplified by the unpredictable stances of both Iran and the United States, as well as the broader geopolitical turbulence involving Israel. Prior to the conflict, few analysts believed Tehran would actually close Hormuz, a threat it has floated intermittently since the 1979 revolution.Given the strait’s pivotal role in the world economy, any prolonged disruption could add a costly premium to global business operations. The International Monetary Fund (IMF) warned in a recent report that wars since 1946 have left “economic scars” lasting more than a decade. The IMF cautioned that even after a ceasefire, persistent political and economic uncertainty can depress investment returns, fuel capital outflows, and constrain both investment and labor supply.In short, while the ceasefire has delivered a short‑term boost to markets, the underlying energy‑price pressures and geopolitical risks mean that the relief is far from absolute.

Footage captured on the streets of Tehran shows small groups of citizens gathering around Enghelab Square – a historic rally point for pro‑regime supporters – some waving Iranian flags, others draped over their backs. The atmosphere is far from uniform; debates and arguments erupted shortly after the ceasefire announcement, reflecting a spectrum of emotions from shock to tentative hope.The video, posted by Majid Nouri – son of former prison official Hamid Nouri – includes his running commentary. He notes that the discussions began around 3 a.m. and continued into the morning, with participants expressing both anger and disbelief. "In no way do we trust America," Nouri declared, echoing a sentiment he says is shared by virtually every Iranian.Pro‑government demonstrators were heard chanting "Death to America, death to Israel, death to compromisers!" and burning U.S. and Israeli flags, according to the Associated Press. The chants persisted despite attempts by organizers to calm the crowd, underscoring the depth of anti‑Western feeling among hardliners.While the ceasefire halted active hostilities, the war has already claimed at least 1,900 lives in Iran. With internet services largely blacked out, gauging the broader public mood is challenging, but pockets of Tehran reported subdued celebrations in the early hours of Wednesday.Local resident Ali, a 31‑year‑old, summed up the prevailing uncertainty: "Most people here don’t trust the US and still don’t know exactly what is going to happen, so they are unsure whether they should be happy or worried." He warned that the ceasefire’s two‑week duration offers no guarantee of lasting peace.Business owners are beginning to test the waters. Hamid, a 43‑year‑old shopkeeper whose grocery and cleaning‑supplies store closed after the February bombings, said, "Today feels like there is no war," and he has reopened his shop, hoping to recover lost income for his family.Iranian officials are framing the pause as a diplomatic victory. Former foreign minister Ali Akbar Velayati posted on X that the conflict has reshaped the global power balance, positioning Iran within a new multipolar order. President Masoud Pezeshkian praised the ceasefire as the fruit of the blood of Iran’s “great martyred leader” and the collective will of the people.Strategically, the ceasefire highlights Tehran’s ability to disrupt the vital Strait of Hormuz, a chokepoint for global oil shipments. Analysts note that this leverage could bolster Iran’s negotiating stance, even as former U.S. President Donald Trump previously warned that a full‑scale clash would threaten "a whole civilisation." As sunrise illuminated the capital, daily life resumed with shops reopening and traffic returning to the streets, yet the prevailing mood remains a blend of exhaustion, cautious optimism, and lingering mistrust of the United States.

At a Pentagon briefing, Defense Secretary Pete Hegseth asserted that Iran’s request for a temporary cease‑fire was a direct result of the United States’ intensive air campaign, which he described as having reduced Iran’s weapons factories to rubble and rendered its military ineffective for years to come. Hegseth, standing beside Joint Chiefs Chairman Dan Caine, said the final wave of strikes before President Donald Trump announced a two‑week pause had completely destroyed Iran’s defense industrial base. While Iran can still fire from existing stockpiles, it can no longer replace lost munitions, according to the secretary. President Trump posted on Truth Social that he had agreed to suspend hostilities less than two hours before his self‑imposed deadline to “decimate the entirety of Iranian civilization.” The decision followed a last‑minute diplomatic push by Pakistan’s Prime Minister Shehbaz Sharif and army chief Gen Asim Munir. Iran’s foreign minister Abbas Araghchi confirmed Tehran’s acceptance of the pause, and the country’s supreme national security council announced it would send a delegation to Islamabad for formal talks starting Friday. Both sides claimed victory: Iran’s security council said it had achieved “nearly all the objectives of the war,” while the United States highlighted the crippling of Iran’s military capabilities. The cease‑fire ends a conflict that began on 28 February, when the U.S. and Israel launched nearly 900 strikes in a 12‑hour window against Iranian military infrastructure, missile sites, and leadership. The opening day saw the death of Supreme Leader Ali Khamenei, with his son Mojtaba Khamenei named successor on 8 March. Hegseth warned that the United States had prepared additional strikes on Iran’s power plants, bridges and energy infrastructure—targets he said Iran could not defend or rebuild for decades—if Tehran had refused the pause. According to Joint Chiefs Chairman Caine, 13 U.S. service members were killed during the fighting. Total casualties across the region exceed 5,000, including over 1,600 Iranian civilians and at least 1,497 deaths in Lebanon. By the sixth day of the war, U.S. military spending had reached roughly $12.7 billion, with a pending supplemental request of $200 billion before Congress. The future of a lasting settlement remains uncertain. Trump later announced that Iran would hand over its enriched uranium and cease all enrichment activities, while Iran’s supreme national security council released a 10‑point counter‑proposal that explicitly demands the right to continue enrichment. Disagreements also persist over the cease‑fire’s scope. Israel maintains that the pause does not apply to Lebanon, where ground and air campaigns are at their most intense since Israel’s northern invasion. Both Pakistan and Iran, however, have stated that Lebanon is included in the cease‑fire. Subsequent reports indicated Iranian missile and drone attacks on Kuwait and the United Arab Emirates, as well as strikes on Iran’s oil infrastructure on Lavan Island. Iran’s supreme national security council warned that its forces remain on high alert, stating, “our hands are on the trigger, and any mistake by the enemy will be met with full force.” When asked about the long‑term U.S. presence in the region, Hegseth replied unequivocally: “We’re not going anywhere.”