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The Final ShowdownSalut! The teenage prodigy vs the 24-year-old qualifier and 500-1 outsider; as paths to a first grand slam final go, Mirra Andreeva's and Maja Chwalinska's couldn't be more different.Two Contrasting JourneysAndreeva, having burst on to the WTA Tour as the most precocious of 15-year-olds in 2023, before reaching the French Open semi-finals in 2024, has long been tipped for major glory, and now, aged 19, the Russian appears to be finding the temperament to add to her tremendous talents and take that final step.Chwalinska, after moving through the junior ranks in Poland with Iga Swiatek, struggled to break through as a pro, and after failing to qualify for Wimbledon in 2021 she took an indefinite break from tennis because of depression. "I pushed at the beginning, but then I just couldn't get out of bed any more," she says. "I was lifeless. I knew I needed to take a break. I honestly didn't know if I was going to come back."The Qualifier's Remarkable RunWhen she did feel strong enough to return she qualified for her first ever grand slam, winning one round at Wimbledon in 2022, her only match victory at a major before this incroyable and improbable stroll in Paris, which started in qualifying 19 days ago. Nine victories and just one dropped set later, Emma Raducanu's tag as the only qualifier to have won a slam is under threat, and the only stress has been how she would pay her hotel bill in the early rounds – not a problem now she's guaranteed at least £1.2m for reaching the final.Playing Styles and ChallengesWhat has made the diminutive Chwalinska's run even more entertaining is the way in which she's done it, with her craft and cunning confounding her more powerful opponents, offering a throwback in a sport dominated by huge hitters. But the problem for Chwalinska today is that Andreeva isn't only able to hit the ball hard – she marries that with huge variety and boasts one of the highest IQs in tennis. In Andreeva, Chwalinska is facing a far more accomplished version of herself.Andreeva's Mental TestIt means the toughest battle for Andreeva today could lie on her own side of the net: can she maintain her new-found emotional equilibrium and deal with being the standout favourite in the biggest match of her life? It's going to fun finding out.La finale commence: 15h à Paris/2pm UK. Restez à l'affût!

The LeadDiagnostic interviews for mental health conditions, commonly used to diagnose disorders including depression, anxiety, bipolar, and personality disorders, show significant variation in reliability according to a new study published in Jama Network Open. The research challenges the long-held assumption that these interviews serve as a definitive "gold standard" for mental health assessment.The Study's Findings on Diagnostic ReliabilityLaura Duncan, a psychiatry professor at McMaster University in Ontario, Canada and one of the study's authors, pointed out that diagnostic interviews "continue to be widely viewed as the best available approach, possibly due to the lack of better alternatives." The review study brings together evidence from studies on "test-retest reliability" of diagnostic interviews from February 2024 to September 2025.The study's authors used Cohen's kappa coefficient to estimate reliability, measuring how often patients would receive the same diagnosis when given the same diagnostic interview twice, accounting for chance agreement. The average reliability was generally better for substance use disorders, with opioid use disorder showing the highest overall reliability. Duncan attributed this to substance use disorder criteria being largely behavior-based, making them easier to quantify than symptoms like sadness or anxiety.The Data Analysis: Interview Types and Their LimitationsThe review included papers on various diagnostic tools including the Structured Clinical Interview for DSM 5 (SCID) and Mini International Neuropsychiatric Interview (Mini), as well as tools for specific disorders like the Clinically Administered PTSD Scale (Caps).Dr. Michael First, a psychiatrist and professor at Columbia University who authored the SCID, criticized the study for lumping "fully structured" and "semi-structured" interviews together. Fully structured interviews follow a strict script and are more likely to yield consistent results, while semi-structured interviews allow clinicians to ask follow-up questions based on patient responses, potentially leading to more accurate diagnoses but also more variability between sessions.Despite these limitations, both experts agree that more objective laboratory tests for mental conditions are needed, though First noted that psychiatrists have been hoping for such tests "for 50 years" without success.The Impact Analysis: Shaping the Future of Psychiatric DiagnosisThe study highlights a critical need for more rigor in psychiatric diagnosis methods. While diagnostic interviews remain the primary tool for assessment, their variable reliability raises questions about the consistency of mental health diagnoses across different settings and providers.The research underscores the challenges in mental health assessment, where subjective reporting of symptoms often forms the basis of diagnosis. This variability can have significant implications for treatment decisions, research outcomes, and patient care across healthcare systems.The criticism from experts like Dr. First also points to methodological challenges in studying diagnostic tools themselves, including inconsistent reporting of interview formats and designs in research literature.The Prediction: Toward a New Diagnostic ParadigmLooking forward, Duncan suggested an alternative approach where clinicians "move away from strict diagnostic categories, where a condition is either present or absent, and think about symptoms on a spectrum or continuum." This shift could potentially lead to more nuanced understanding and treatment of mental health conditions.As the field continues to evolve, there's a clear need for both improved diagnostic instruments and more comprehensive research comparing different interview methodologies. The study's authors emphasize that the limitations identified in current diagnostic approaches should motivate further development of more reliable assessment tools in psychiatry.

The Lead: The Derby 2026 Unfolds at Epsom The 247th running of The Derby, the most famous Classic in horse racing, is underway at Epsom Downs with 14 runners vying for the prestigious title. Guardian's Greg Wood provides live coverage, previews, and expert picks for the day's major races including the Derby Stakes, Dash Handicap, and Coronation Cup. The Event Details: Race Previews and Analysis The Derby Stakes, scheduled for 4pm BST, features 14 horses competing to become the 247th horse on the Derby's roll of honor. Recent rain has affected the going, adding an element of unpredictability to the race. Other key races include the 3.15pm Dash Handicap and the 2.40pm Coronation Cup, which features last year's winner, last year's Derby winner, and the officially top-rated horse on the planet, Calandagan. The Data Analysis: Form Guide and Key Contenders For the Derby Stakes, several horses stand out based on recent form. Benvenuto Cellini's Chester Vase win and the competitive Lingfield race between Maltese Cross and Bay Of Brilliance are noted as strong form indicators. Item could become the fifth Dante winner this century to add the Derby to his record, while Ancient Egypt is ready to live up to his pedigree and price tag for Kia Joorabchian and Charlie Johnston. In the Dash Handicap, a field of 20 runners will compete over the minimum five-furlong trip. The high numbers generally hold sway in races at this distance, and the speedy nature of the track means the pace tends to hold up. Kinswoman, the favorite, and Lexington Buzz are expected to perform well, with Irish raider Eclairage also showing promise. The Coronation Cup features an exceptional lineup, including last year's winner Lambourn, last year's Derby winner Jan Brueghel, and the World's Best Racehorse in 2025, Calandagan, who has been on an unbeaten five-race spree at the sport's highest level. The Impact Analysis: Significance in the Horse Racing Calendar The Derby remains one of the most prestigious races in the global horse racing calendar, attracting the best three-year-old thoroughbreds from around the world. The event's cultural significance extends beyond the sport, with celebrities like Mary Berry and Jodie Kidd attending, adding to the pageantry and tradition of the occasion. The rain-softened ground conditions have added an element of unpredictability, potentially favoring horses with proven form on similar surfaces. This could lead to surprises and potentially create new stars in the sport. The Prediction: Expert Picks and Race Outlook Greg Wood has made his selections for the day's key races. For the Derby Stakes, he favors Bay Of Brilliance as an each-way option, citing the strength of the Lingfield form and the advantage of stall position for the horse. For the Dash Handicap, he recommends Eclairage from stall 14, noting the tendency for high-numbered horses to perform well in this race. In the Coronation Cup, Calandagan is the clear favorite, with Wood expecting him to continue his unbeaten streak at the sport's highest level.

Weather Disruption and Match Status The third day of the first Test at Lord's has been marred by persistent rain, leaving players and spectators under gunmetal skies. While the forecast for Day 4 looks promising, today's prospects are bleak, with a high percentage chance of rain through most of the day. The Matt Henry Masterclass and Gay's Debut Milestone The match has progressed at a rapid rate due to skilful bowling on both sides in helpful conditions. Matt Henry delivered a historic delivery to Jacob Bethell, described by Test Match Special as the least bouncing ball in the past 20 years in a specific pitch zone, effectively shooting out the young batter. Meanwhile, Emilio Gay marked his Test debut with a resilient maiden half-century, showcasing the resilience required on this unpredictable pitch. Scoreline and Weather Forecast New Zealand requires 218 more runs to secure victory, with openers Devon Conway and Ravindra Ravindra currently holding the fort. The batting on display has been intense, with Harry Brook and Kyle Jamieson delivering vital contributions in the first innings. Series Dynamics and England's Bowling Pressure England holds a slight edge with three wickets in hand, but New Zealand is only one solid partnership away from turning the tide. The aggressive batting styles seen in the first innings have set a high bar, and the pitch contains the dual threat of unexpected lift off a length and scudding ankle-height balls. Day 4 Outlook With improved weather expected tomorrow, a decisive result is imminent. The match is poised to move from a stalemate to a finish line, making Day 4 the critical day for both teams.

The EU Sanctions and Settler Leaders’ Defiant ResponseWhen the European Union announced a new tranche of sanctions targeting Israeli settler organisations and their leaders, the reaction was unexpectedly celebratory. Regavim, co‑founded by Finance Minister Bezalel Smotrich, and activist Daniella Weiss of the Nachala movement both dismissed the penalties as a “badge of honour” and “ridiculous”. Their statements signal a broader refusal to be swayed by diplomatic pressure.Sanctioned Entities and the Scope of EU MeasuresThe EU’s package targeted:Regavim – a settler‑rights NGO linked to Bezalel SmotrichNachala – led by Daniella Weiss, known for border‑area conferences on settlement expansionAmana – a cooperative that finances West Bank settlementsMeir Deutsch – director of RegavimIn total, four entities and three individuals were listed. The sanctions complement earlier actions by the United Kingdom, Canada and other allies that targeted Smotrich for alleged support of violence in the West Bank.Casualties and Displacement Figures Since October 2023Human‑rights monitors have documented a sharp rise in settler‑related violence after the October 2023 Hamas attack. Reported figures include:1,168 Palestinians killed in the occupied West Bank12,666 injured33,000 displacedNearly 23,000 Palestinians detained, many without chargeThese statistics illustrate the human cost accompanying the settlement push.Implications for the Israeli‑Palestinian Conflict and International PressureAnalysts argue that the EU’s “toothless” sanctions may inadvertently grant domestic prestige to hard‑line settlers. The lack of tangible repercussions—settlers rarely travel to Europe and thus feel little personal impact—means the measures are unlikely to curb expansion or hold perpetrators accountable. The article notes a “closed loop” of entitlement, where settler ideology, state support, and military backing reinforce each other, sustaining a climate of impunity.Outlook: Prospects for Settlement Expansion and Diplomatic LeverageGiven the settlers’ defiant stance and the Israeli government’s ongoing endorsement—exemplified by plans for the E1 corridor linking East Jerusalem to Maale Adumim—future settlement growth appears probable. Without stronger, enforceable international actions, the EU sanctions risk remaining symbolic. Observers warn that continued violence and displacement will likely persist, further complicating any diplomatic pathway toward a two‑state solution.

The Rise of Middle-earth: Tolkien's Triumph Over Literary ClassicsIn a remarkable shift from established literary canon, JRR Tolkien's The Lord of the Rings has topped The Guardian's readers' poll of the 100 greatest novels published in English, displacing George Eliot's Middlemarch from its previous position. The trilogy, which didn't even feature when authors, critics and academics made their selection, has resonated deeply with readers across the globe, from Uruguay to the Isle of Skye, Albuquerque to Sydney.The Enduring Appeal of Epic FantasyThe Lord of the Rings' victory speaks to its unique ability to connect with readers on a fundamental level. As one Alabama voter noted, the novel contains "profound meaning about the importance of life, sacrifice, the natural world, corruption of power, the evils of war, generosity of spirit." Its influence extends across generations and cultures, with readers from various backgrounds citing its immersive world-building, complex themes, and emotional resonance as reasons for its enduring popularity.The novel's journey to the top is particularly noteworthy given its unconventional publication history. Originally conceived as a single work but published as a trilogy after negotiations between Tolkien and his publisher, the series has transcended its format to become a cultural touchstone. Readers have been drawn to its blend of ancient mythological elements with modern storytelling techniques, creating what one voter described as a world that "still persists in my memory."Notable Shifts in Literary RankingsReaders exercised their power to significantly reshape the literary landscape compared to the previous critics' list. Joseph Heller's Catch-22, which "just squeaked into the first list," has now jumped to the eighth position, ranked higher than established classics like Ulysses, Anna Karenina, and The Great Gatsby. Similarly, David Foster Wallace's Infinite Jest, absent from the original list, now sits in 31st position, sharing its ranking with The Master and Margarita, The Poisonwood Bible, and The Remains of the Day.The list also reveals interesting patterns in reader preferences compared to critics. While Victorian literature maintains a strong presence, with Middlemarch's "consistent showing" and other works by Eliot, Dickens, and Hardy, readers have elevated contemporary works that critics may have overlooked. The enduring popularity of Jane Austen, readers' most nominated writer overall, demonstrates the continued relevance of classic literature in modern reading culture.The Absence of Literary Giants and Changing TastesStaggeringly, the list shows no recognition for work by several male titans of recent American literature—no Bellow, no Roth, no Updike, no DeLillo. This absence highlights the "waxing and waning of reputation" and the "speed with which literary fashion forms and reforms." Similarly, some English novelists who were once central to cultural life—no Iris Murdoch, or CP Snow, or Angus Wilson—failed to make the cut.The list also reveals a notable absence of lighter, humorous works. While Terry Pratchett and Douglas Adams secured places with their respective series, other comedic authors like PG Wodehouse, Nancy Mitford, and Jerome K Jerome were overlooked. This raises questions about how "best" often equates to "serious" or "weighty" literature in critical assessments, despite the inherent value of humor in storytelling.The Future of Literary Canons and Reader InfluenceThis readers' poll demonstrates the power of audience participation in shaping cultural narratives. Unlike previous lists compiled by critics and academics, this one reflects the genuine preferences of a diverse readership, leading to a more eclectic and contemporary selection of works. The inclusion of newer entries like John Kennedy Toole's A Confederacy of Dunces—published posthumously and now sharing the 32nd position—suggests that readers are more willing to embrace overlooked or rediscovered literary gems.As literary tastes continue to evolve, we can expect similar shifts in how we value and rank literature. The enduring popularity of works like The Lord of the Rings, which combines epic storytelling with universal themes, suggests that readers continue to seek narratives that transcend time and place. While established classics will always have their place, the growing influence of reader preferences may lead to a more diverse and inclusive literary canon in the future.

The Lead Doctors, scientists, and researchers shared new research about ways to tackle cancer at the 2026 American Society of Clinical Oncology (Asco) annual meeting, the world's largest cancer conference. Breakthroughs in Cancer Treatment The event in Chicago, attended by 40,000 health professionals, featured more than 200 sessions and 2,700 poster presentations on this year's theme, “the science and practice of translation: improving cancer outcomes worldwide”. Smart Drugs in Cancer Treatment Researchers have developed a smart drug that stops cancer cells hiding. The experimental tablet, GRWD5769, can help shrink tumours by at least 30% in six of the world’s most common forms of the disease, delegates in Chicago were told. 26 of 83 patients with cervical, bladder, liver, bowel, lung or head and neck cancers who were given GRWD5769 alongside cemiplimab had tumour reductions of at least 30%. 15 had tumour reductions of at least 30%. A Daily Pill for Pancreatic Cancer A pill that doubles survival time in patients with pancreatic cancer was presented at the conference. In a trial of 500 patients, all of whom had pancreatic cancer that had spread, the pill, daraxonrasib, doubled survival time, with fewer side-effects compared with chemotherapy. Patients who took the drug lived substantially longer, for an average of 13.2 months, compared with 6.6 to 6.7 months for patients who had chemotherapy. Safely Skipping Some Treatments Some patients can safely skip some treatments, according to research presented at the conference. A genomic test could pave the way for a new era of personalised medicine, enabling doctors to determine which patients can safely skip chemotherapy. The Optima trial, led by University College London, followed 4,000 patients with newly diagnosed breast cancer in the UK, Norway, Sweden, Australia, New Zealand and Thailand. Those with a low score on the genomic test could be treated safely with hormone therapy alone. The Future of Cancer Treatment Urgent action is required to cope with rising cancer cases. The world faces a cancer workforce crisis, experts said, with a shortage of 100 million staff expected by 2050 when 100,000 people will be being diagnosed every day. A 21% increase in cancer incidence is predicted, according to a report presented at the conference. The rate is set to rise from 165 per 100,000 people in 2025 to 200 per 100,000 in 2050.

The Origins of 'Mogging' Until recently, if someone had said "mog" to me, I probably would have assumed they were talking about the children's book cat created by the late great Judith Kerr. If asked about "mogging" or being "mogged," I would have been completely baffled. But for many members of gen Z and gen Alpha (or anyone who is just a bit too online), the slang term, which means to outdo or outshine others, is everywhere. From Manosphere to Mainstream Mogging's origins are in the manosphere, where it began as a verb derived from the acronym "Amog" (alpha male of the group). In misogynistic forums in the 2010s, to "mog" came to mean to outdo someone in terms of sexual desirability. Mogging has been adopted by "looksmaxxing" influencers such as Braden Peters, known online as Clavicular, who encourage men to try to alter their looks – sometimes in extreme ways – to increase their "sexual market value". Such an influencer might talk of "frame mogging" another person in a photo or video – a variation on mogging that specifically refers to being more muscular. The Evolution of Competitive Language Even now, as the term has begun to be used much more widely, and in a tongue-in-cheek way, it is still typically associated with looks (a friend of mine, for example, was described by her boyfriend's younger siblings as "mogging him" in a photo). But increasingly, mogging can mean besting others at basically anything. The gold medal Olympic figure skater Alysa Liu said in an interview last year that her main competition strategy was "to mog", while a 23-year-old colleague of mine tells me that she and her friends joke about "walk-mogging" when they overtake people on the street. Linguistic Analysis of Modern Slang Tony Thorne, director of the slang and new language archive at King's College London, says a lot of new slang terms "have come recently from the same kind of male-based internet culture", referencing the words "simp" (someone who is excessively attentive), "soy boy" (a derogatory term for a man who is not stereotypically masculine) and "sigma" (someone cool and successful). Not to mention "maxxing," now such an established part of the lexicon that it was tweeted by the US Department of Defense earlier this year. The Cultural Impact of Competitive Slang Thorne thinks it is significant that "mogging" in particular has become fashionable at this time. "What it implies – hyper-competitive, hyper-individualist, aggressive selfishness" has become "mainstream behaviour", he says. Which is why Will Adolphy, a psychotherapist who was himself once an ardent follower of manosphere influencers, has concerns about the word. "Part of me can see how it's a kind of handy, even entertaining word," he says. But the idea of mogging "reinforces this sense that there are certain people that will dominate others based off their physical appearance and status", he says. Psychological Concerns About Competitive Language Dr Emily Sehmer, an NHS child and adolescent psychiatrist, worries too about the "constant sense of competition" that concepts such as mogging help to foster, especially for teenagers, who are developing their socio-emotional skills and typically "have a desire to fit in and to get peer approval". Apart from anything else, she adds, wanting to mog someone is "kind of mean, isn't it?" The Ironical Reappropriation of 'Mogging' "I think people are right to be concerned," about the rise in usage of slang that originates from a toxic subculture, Thorne says – and notes that some of his fellow linguists feel uncomfortable about researching it. But, he adds, "mogging" has moved well beyond its origins, and many people who use it now "tend to understand it and laugh at it, and they use it themselves, but ironically". Certainly, plenty of mogging content on social media now has an irreverence to it: such as the trend of posing for the photo on a rollercoaster in order to "mog" the screaming riders next to you. Making what started as an aggressive concept into something very silly pokes fun at the ridiculousness of the manosphere, my younger colleague explains. She shows me a picture of herself on a recent holiday, standing next to a statue of Napoleon, that she sent to a group chat of her friends. The caption? "I mogged Napoleon!"

The LeadOn a working farm, wildlife has found innovative ways to establish homes in the most unexpected places, from inside farm machinery to within hay bales, demonstrating nature's remarkable adaptability to human environments.Unexpected Wildlife HabitatsThe farmyard has become a sanctuary for various bird species, each finding unique nesting spots among the equipment and structures. Pied and grey wagtails accompany daily wheelbarrow trips to the muck heap, making aerial assaults on insects. Swallows thrive in the environment rich in midges and flies around warm-blooded animals, while mud from regular water bucket sloshing provides material for nest repairs.Hay bales, when opened, reveal surprising residents. Tash, who keeps her shire cross Jack at the farm, recently discovered a robin's nest inside a new hay bale, with the adult bird happily resettling on her eggs. Two years prior, one side of a haystack had to be avoided completely until a tawny owl successfully raised two owlets within it.Farm Machinery as Avian ApartmentsPerhaps most remarkably, a retired reversible five-furrow plough has been transformed into a blue tit nursery. The birds bring caterpillars from field oaks and drop them down a narrow shaft in the hollow steel frame above the landwheel. Inspection reveals a long, thin nest filled with baby blue tits, their yellow clown gapes pressed shut at human presence, safe from woodpecker bills.Other farm machinery has similarly become wildlife habitats. A retired sprayer sitting among nettles houses tree bumblebees in its hollow mechanical arms. Another blue tit nest was discovered in a hole in the cap of a Haybob 300, a contraption that spreads, tedders, and dries cut hay before gathering it for baling.The Fragile Balance of CoexistenceThese observations reveal a delicate relationship between agricultural operations and wildlife. While farmland birds may struggle in open fields, the farmyard provides precarious sanctuaries for certain species. The timing of these nesting cycles is particularly critical, as both broods of tits fledged just ahead of a heatwave that might have suffocated those in the steel plough casing and risked farm accidents with the machinery nests.Future of Wildlife in Agricultural SettingsAs agricultural practices continue to evolve, these unexpected wildlife habitats may become increasingly important for biodiversity. The coexistence of farming operations and wildlife demonstrates how even in human-dominated landscapes, nature finds ways to adapt and thrive. This delicate balance suggests that thoughtful farm management can potentially support wildlife populations while maintaining agricultural productivity.