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President Donald Trump escalated rhetoric on Thursday, stating that the United States has yet to begin a full‑scale campaign against Iran’s remaining infrastructure and hinting that bridges and electric power plants could be next targets. The comment followed the release of video showing a U.S. strike on the newly completed B1 bridge that connects Tehran to Karaj, an attack that Iran reports killed eight people and injured 95. Iranian Foreign Minister Abbas Araghchi condemned the strike on civilian infrastructure, describing it as evidence of the “defeat and moral collapse” of the aggressor. In a statement posted on X, he warned that such attacks would not force Iran to surrender. The conflict, now entering its fifth week, has begun to ripple through regional and global markets. Instability around the Strait of Hormuz—a vital conduit for oil and gas—has prompted nations to scramble for alternative shipping routes. Satellite images this week captured smoke over Iran’s Qeshm Island, underscoring the heightened risk to infrastructure near the strategic waterway. Amid stalled negotiations with Iran’s new leadership, Trump’s intensified language comes as the United Nations Security Council prepares to vote on a resolution that could authorize member states to use “defensive means” to keep the strait open. Araghchi warned that any provocative action in the Council would only worsen the situation. Iranian media have begun listing potential retaliation targets, naming major bridges in Kuwait, Saudi Arabia, the United Arab Emirates and Jordan as possible future strike points. The semi‑official Fars News Agency highlighted these crossings as vulnerable following the Karaj bridge attack. The Islamic Revolutionary Guard Corps (IRGC) claimed responsibility for recent strikes on U.S.-linked industrial sites in the Gulf, including steel facilities in Abu Dhabi and aluminium plants in Bahrain. The IRGC warned that if attacks on Iranian industries continue, “the next response will be much more painful” and will focus on the occupier’s core infrastructure. Health infrastructure has also suffered. Iran’s Health Ministry reported that U.S. and Israeli raids severely damaged the Pasteur Institute of Iran, a key research center for diseases such as cholera and COVID‑19. Ministry spokesperson Hossein Kermanpour called the strike “a direct assault on international health security.” WHO Director‑General Tedros Adhanom Ghebreyesus echoed the condemnation, noting that the institute is now unable to deliver health services. The WHO has documented more than 20 attacks on Iranian healthcare facilities since the start of March. In a separate claim, Iranian officials said air defenses downed a second U.S. F‑35 fighter jet over central Iran, suggesting the pilot’s survival was unlikely. The United States has not responded to the allegation. Israel’s military reported a fresh barrage of Iranian missiles, which triggered air‑defence alerts and caused damage to homes, vehicles, and a train station in Tel Aviv. The widening hostilities, combined with threats to critical energy and health infrastructure, highlight the growing regional volatility and its potential to disrupt global markets.

The recent statements and actions by the US, particularly by President Donald Trump, have raised serious concerns about potential war crimes under international law. During a national address, Trump warned that if Iran did not reach a deal with him, the US would target Iranian electric-generating plants and reduce the country to the 'stone ages.'Legal experts and human rights organizations have strongly criticized these threats. Erika Guevara Rosas, Amnesty International's senior director of research, advocacy, policy and campaigns, emphasized that intentionally attacking civilian infrastructure, such as power plants, is generally prohibited under international law. Such actions could cause disproportionate harm to civilians and are considered unlawful and potentially war crimes.More than 100 US experts in international law from prestigious universities, including Harvard, Yale, and Stanford, have expressed similar concerns. They highlighted Trump's comments, including the statement that the US may conduct strikes on Iran 'just for fun,' and Defense Secretary Pete Hegseth's remarks about not fighting with 'stupid rules of engagement.'The experts and legal experts point to the principle of distinction in international humanitarian law, which requires parties to avoid targeting civilian objects. Article 52 of the Geneva Conventions defines civilian objects as those that are not military objectives, and it is a war crime to intentionally direct attacks against them if they are not military objectives.Human rights organizations and experts warn that targeting Iran's power plants would have a devastating impact on the civilian population, affecting hospitals, water supplies, and other vital needs. Sarah Yager, Washington director of Human Rights Watch, noted that such actions would be catastrophic for the Iranian people.

The conflict between Iran, the US, and Israel has taken a devastating toll on civilians, with widespread destruction and displacement reported across the country.At the Kapıköy border crossing in eastern Turkey, a mountain pass that serves as one of the few gateways to the west from Iran, many Iranians are fleeing the country due to the intensifying conflict.Amir, a 33-year-old foreign exchange and cryptocurrency trader from Tehran, is one of them. He described the nightly bombardments and said, 'Every night they are bombarding. Boom. Because of the war.'Others, like a pharmacologist from Tehran, are traveling to see their families in Europe, citing anxiety and frustration with the current situation. 'All of the people live with anxiety,' she said. 'We are very tired of the revolution of [the] Islamic republic of Iran.'The UN refugee agency reports that close to 64,000 Iranians arrived in Turkey between March 3 and 30, while more than 48,000 Iranian nationals returned to Iran.The International Organization for Migration estimates that more than 82,000 residential units have been hit by the US and Israeli strikes, affecting 180,000 people.Many at the Kapıköy border point expressed fear and uncertainty about the future, with some saying they were waiting to see what the outcome would be before making a decision.The conflict has had a significant impact on the economy, with part-government-owned corporations ordering people back to work and many businesses forced to close.As the situation continues to deteriorate, many are seeking safety abroad, while others are returning to Iran to be with their families.

Recently obtained footage shows the aftermath of aerial strikes that destroyed a bridge in Iran. The video, which has been making rounds in media circles, provides a visual testament to the significant damage incurred by the region's infrastructure. The bridge, a crucial connectivity link, was completely destroyed in the strikes, raising concerns about the humanitarian and economic implications for the local population. While specific details about the strikes, including the perpetrators and the exact date, remain scarce, the footage underscores the severity of the situation in the region. The incident has sparked international attention, with many calling for an investigation into the circumstances surrounding the strikes and their impact on civilian life. As the situation continues to unfold, the international community remains on high alert, monitoring developments and assessing the broader implications for regional stability.

Meanwhile, powerful blasts rocked northern Tehran, as Israel said it had launched a new wave of strikes on the Iranian capital and Beirut. The Associated Press also reported, citing an Israeli official, that Israel had suspended airstrikes in areas 'relevant' to the rescue operation in Iran.

Iraq is facing a balancing act as the US-Israeli war on Iran exposes deep divisions within the country. The conflict has highlighted the divisions between those who view the attacks on Iran as a means to end Tehran's longstanding influence over Iraqi politics and those who are loyal to the Islamic republic. The war has struck Iraq during a precarious power vacuum, following the stepping aside of caretaker leader Mohammed Shia al-Sudani, whose coalition won the largest share of seats in November's parliamentary elections. This power vacuum has exacerbated tensions, with factions from the Islamic Resistance in Iraq, an umbrella body of Iran-backed armed groups, vowing to drag the US into a long war of attrition. The group has claimed responsibility for numerous drone and missile attacks on targets in Iraq and neighboring countries, including the US base in Erbil and the city's international airport. In response, unclaimed airstrikes attributed to US and Israeli forces have hit positions across the country, killing several commanders and fighters. Iraqi leaders are attempting to maintain a balancing act, denouncing the killing of Iran's supreme leader Ali Khamenei while rejecting attempts by Tehran to draw Iraq into the conflict. However, this balancing act is complicated by the fact that pro-Iran groups are also members of the Popular Mobilisation Units (PMU), a sprawling institution that operates with its own agenda. The conflict has significant implications for Iraq's stability and economy, with a looming financial disaster hanging over the country due to the crisis over the strait of Hormuz and the loss of oil revenue. The US pressure and threat of sanctions have forced some members of the pro-Iran Shia alliance in Iraq's parliament to distance themselves from more militant factions. The killing of Hassan Nasrallah, the leader of Hezbollah, has also had a profound impact on the Iraqi resistance factions, which have struggled to respond effectively to the recent war. The insider close to the pro-Iran factions noted that the killing of Nasrallah has affected the Iraqi resistance factions more than the killing of Khamenei, as Nasrallah had a direct appeal to many commanders.

The United States has reaffirmed that it is still prepared to engage Tehran in diplomatic talks, despite the ongoing US‑Israel war against Iran and President Donald Trump’s renewed threats to target the country’s civilian infrastructure. State Department spokesperson Tommy Pigott told Al Jazeera that President Trump had pursued negotiations with Iran before the conflict erupted, but accused the Iranian regime of persisting in its quest for a nuclear weapon. "The president is always open to diplomacy, but he’s also clear that we will see our objectives fulfilled here," Pigott said, underscoring the administration’s dual track of diplomatic engagement and military pressure. In a primetime address aired on Wednesday, Trump echoed his earlier claims that the United States is winning the war, yet offered no concrete roadmap for ending the hostilities or reopening the Strait of Hormuz – a chokepoint whose closure by Tehran has driven global energy prices higher. The conflict began on February 28, shortly after a round of Geneva talks that Omani mediators and Iranian officials described as “positive.” Last year, Israel struck Iran’s three primary nuclear facilities in an operation the White House dubbed “Midnight Hammer.” Iran continues to deny any intention to develop a nuclear weapon, while Israel is widely believed to possess an undeclared nuclear arsenal. Former intelligence chief Tulsi Gabbard testified to Congress that Iran was not rebuilding enrichment capacity before the June 2025 attacks, and later reiterated that there have been no efforts to restore its nuclear program since the strikes. Nevertheless, Tehran insists on the right to enrich uranium domestically and has ruled out negotiations over its missile program and support for groups such as Hezbollah and Hamas. Pigott emphasized that the United States is maintaining high‑level diplomatic contacts across the region, stating, "We see diplomatic engagement at the highest levels of this administration, with our partners in the region, to pursue our interests and explore what can happen here." The spokesperson also accused Iran of targeting civilians and civilian infrastructure, describing the threat of a nuclear‑armed Tehran as "intolerable." In response, Iran has launched missile and drone attacks against U.S. and Israeli assets, as well as energy facilities, hotels, and airports throughout the Middle East. Trump later posted footage of a U.S. strike on a major Iranian bridge, warning that similar attacks could follow. He wrote on social media, "IT IS TIME FOR IRAN TO MAKE A DEAL BEFORE IT IS TOO LATE, and there is nothing left of what could become a great country." In the same speech, he threatened to destroy Iran’s power plants and, earlier in the week, suggested the United States could also target water desalination stations – actions that legal experts say would constitute collective punishment under international law. Barbara Slavin, a distinguished fellow at the Stimson Center, told Al Jazeera that Trump appears to be "scrambling" to intensify the war in hopes of forcing a resolution before the conflict turns into a definitive failure.

Pakistan reaffirmed its commitment to steer the United States and Iran back to the negotiating table, even as it faces "obstacles" that were not disclosed by Foreign Office spokesperson Tahir Andrabi during a weekly briefing in Islamabad.The statement came hours after U.S. President Donald Trump warned he would bomb Iran "back to the Stone Ages" if Tehran rejected Washington’s peace terms, underscoring the volatile backdrop to Pakistan’s diplomatic push.Andrabi emphasized that Pakistan will continue to "promote facilitation and dialogue" and is working to create conditions for meaningful negotiations among relevant stakeholders. He noted that both Washington and Tehran view Pakistan as a neutral intermediary.In a tangible sign of confidence, Iran has permitted 20 Pakistani‑flagged vessels to transit the Strait of Hormuz. Andrabi described this as "a harbinger of peace" and a positive step for regional stability, though he did not confirm whether any ships have already sailed.The Hormuz corridor has been largely blocked since Iran curtailed oil and gas shipments after the outbreak of the US‑Israel‑Iran conflict on February 28, driving up energy prices and straining economies across the region.High‑level contact between Islamabad and Tehran continues. Andrabi cited a March 28 call between Iranian President Masoud Pezeshkian and Pakistani Prime Minister Shehbaz Sharif, during which both leaders stressed the need to "build trust" and praised Pakistan’s "supportive role for peace".Regional diplomacy intensified after Deputy Prime Minister and Foreign Minister Ishaq Dar returned from Beijing, where he met Chinese Foreign Minister Wang Yi. The two sides produced a joint five‑point initiative calling for an immediate ceasefire, urgent diplomatic engagement, and the restoration of normal maritime traffic through the Strait of Hormuz.Andrabi said the China‑Pakistan proposal has been shared with the United States, Iran and other stakeholders, receiving appreciation "across the region and beyond". The plan aligns with outcomes from a four‑nation ministerial meeting in Islamabad that included Saudi Arabia, Turkey and Egypt.Despite a hairline fracture sustained during the Islamabad talks, Dar travelled to Beijing, underscoring Pakistan’s strategic partnership with China. He later announced that Pakistan is ready to host direct US‑Iran negotiations in the coming days, a proposal reiterated by Andrabi at the briefing.While Pakistan positions itself as a facilitator, Andrabi acknowledged that Iran has so far limited mediation to indirect messages and has not committed to direct talks, stating, "Iran, as a sovereign country, determines its own policies."In a separate diplomatic track, Pakistan sent senior officials to Urumqi, China, for discussions with Afghanistan – the first substantive contact since Islamabad launched cross‑border strikes in late February. Andrabi stressed that Afghanistan must demonstrate "visible and verifiable actions" against terrorist groups operating from its territory.Pakistan continues its Operation Ghazab lil‑Haq, launched on February 26 to target terrorist sanctuaries in Afghanistan after alleged cross‑border fire from Taliban forces. Following a five‑day Eid‑ul‑Fitr pause, the operation remains ongoing.Islamabad accuses the Taliban‑run Kabul government of allowing the Tehrik‑i‑Taliban Pakistan (TTP) to use Afghan soil for attacks inside Pakistan, a claim the Afghan side denies. China has also facilitated Pakistan‑Afghanistan engagement, hosting meetings in Beijing and Kabul earlier in the year.

Following US and Israeli strikes that killed senior Iranian figures, concerns have emerged about the power dynamics within Iran's leadership. The country's response to these actions and the implications for the region are significant.This episode of 'The Take' examines the key players in Iran's system, how decisions are made, and the potential impact of losing top figures on Iran's response to the ongoing conflict with the US and Israel.Key topics include:The structure of Iran's leadership and decision-making processesThe role of senior figures and their influence on policyThe potential consequences of their loss for Iran's stance on the US-Israel conflictThe analysis features insights from Ali Hashem, a senior Al Jazeera correspondent, providing a deeper understanding of the complexities at play.