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In a stark address delivered as the cease‑fire in the Iran conflict teetered, IMF Managing Director Kristalina Georgieva warned that the war will leave a permanent scar on the global economy, slowing growth beyond the IMF’s original projections for 2026. Georgieva noted that, had the hostilities not erupted six weeks ago, the Fund would have been poised to raise its 2026 growth outlook. Instead, even the most optimistic scenario now entails a downgrade, and a swift return to pre‑war conditions appears unlikely. The uncertainty surrounding the cease‑fire—exacerbated by divergent positions of Washington and Tehran—has already pushed oil prices higher, reflecting fears of continued disruptions to shipments through the Strait of Hormuz, a vital conduit for world energy supplies. According to the IMF’s upcoming World Economic Outlook, the conflict’s “scarring effects” will translate into lower living standards worldwide. The Fund had previously forecast global growth of 3.1% in 2026, a modest slowdown from 3.2% in 2025, buoyed by a tech‑driven investment surge. Georgieva emphasized that the war arrived when the economy was riding “considerable momentum” from technology investment and supportive financial markets. She outlined the mechanisms of damage: damaged infrastructure, supply‑chain interruptions, eroded confidence, and prolonged uncertainty over oil and gas production in the region. These factors will depress growth regardless of whether a peace agreement is ultimately reached. Georgieva highlighted that the most vulnerable will be net oil‑importing nations, poorer economies and small island states, which stand to feel the brunt of higher energy costs and reduced trade flows. She urged governments to avoid unilateral measures such as export bans or price controls, warning that such actions could "pour gasoline on the fire" and further destabilise markets. With many countries already carrying elevated debt levels and higher borrowing costs, the IMF chief called for targeted, temporary assistance to protect the most at‑risk households. She cautioned against broad tax cuts or blanket energy subsidies, which could stoke inflation and strain fragile public finances. Central banks, she added, should keep policy rates steady while remaining ready to act against inflationary pressures. Bank of England Governor Andrew Bailey, who also chairs the Financial Stability Board, echoed the IMF’s concerns, describing the conflict as a "very big shock" that has heightened market volatility. He stressed that the situation remains fluid and that policymakers must stay vigilant. Overall, the IMF’s message is clear: the Iran war will reshape the global growth trajectory for the foreseeable future, and coordinated, prudent policy responses are essential to mitigate its lasting impact.

OpenAI has put on hold plans for a landmark UK investment, Stargate UK, citing high energy costs and regulation, in a blow to the government which has put AI at the centre of its growth strategy.The Stargate project was part of the UK-US AI deal announced last September, in which US companies appeared to commit £31bn to the UK’s tech sector. The project aimed to support Britain in building out “sovereign compute” – infrastructure that would allow the government and other UK institutions to run AI models on datacentres in the country.Victoria Collins MP, the Liberal Democrat spokesperson for science, innovation and technology, said: “This is a wake-up call for the government to manage energy costs in the UK and foundation infrastructure.”The Labour MP Clive Lewis said: “When a government has no economic strategy worthy of the name and no real industrial vision, it becomes vulnerable.”An OpenAI spokesperson said: “We see huge potential for the UK’s AI future, and we support the government’s ambition to be an AI leader. We continue to explore Stargate UK.”High energy costs, rising further because of the US-Israel war on Iran, are expected to delay or derail AI datacentre projects worldwide. The UK’s industrial electricity prices were already the highest in Europe before the start of the war.

UK Prime Minister Keir Starmer has expressed his concern over Israel's ongoing attacks on Lebanon, emphasizing that they 'shouldn't be happening' and must stop immediately. During his visit to the Middle East, Starmer called for the Iran conflict to be a turning point for the UK's future security. In an article for the Guardian, Starmer outlined the need for a fundamental reset in the UK's approach to make the country more resilient, including boosting defense and strengthening ties with Europe. He highlighted the importance of not being drawn into offensive military action, while rebuilding European alliances and increasing defense capacity. Starmer's comments echo those of Yvette Cooper, the foreign secretary, and John Healey, the defense secretary, indicating a potential divergence between the UK and the US under Donald Trump over the Iran conflict. The UK has been adamant that the Strait of Hormuz must remain free of tolls or levies, contrary to Trump's suggestion of a 'joint venture' between the US and Iran. Starmer criticized Israel's intensified bombing in Lebanon, which has resulted in over 250 deaths. He emphasized that the issue is 'a matter of principles' and not a technical one, dismissing arguments that the attacks are not part of the ceasefire agreement. The UK's stance has been to support the ceasefire and advocate for the inclusion of Lebanon in the agreement. Starmer also emphasized the need for the UK to be closer to the EU on defense, security, trade, and energy to strengthen the economy and make it more resilient. He highlighted that the war in Iran must be a 'line in the sand' and that the UK's response will define its future for a generation.

On All Hallows' Eve in 1517, Martin Luther, a 33-year-old German priest and scholar, took a pivotal step that would change the course of history. He marched up to the church in Wittenberg and nailed a document to the door, containing 95 statements, or theses, protesting against corruption in the church.Luther's actions led to his excommunication and a dramatic escape, but they also marked the beginning of the Reformation. As a musician himself, Luther knew the power of music in spreading his new doctrine. He saw music as a divine gift 'next to theology' and used it to incite people to do good and to teach them.Luther's hymns, known as chorales in the German-speaking world, were simple, memorable tunes, often adapted from popular melodies, repeated verse to verse. The words were in everyday German, and the hymn tunes were harmonized with simple, block chords, making it possible for anyone to sing along.One of Luther's most famous hymns, Ein feste Burg ist unser Gott (A Safe Stronghold Our God is Still), is still sung today in churches around the world. His hymns were widely distributed using the relatively new technology of the movable type printing press, invented by Johannes Gutenberg.Luther's musical legacy continued to influence composers, including Heinrich Schütz and Johann Sebastian Bach, who composed new chorales and clothed existing ones in rich harmonies. Bach's chorale preludes, where an elaborate melodic line unfolds until the chorale tune emerges, remain iconic.The chorales have also had a lasting impact on popular music, with arrangements by artists like the Swingle Singers and Myra Hess, and even influencing 1970s pop music, such as Apollo's 'Joy' and The Beach Boys' 'Lady Lynda'.

Amazon announced that, effective 20 May 2026, it will stop delivering software updates to Kindle and Kindle Fire devices launched in 2012 or earlier. The decision targets a range of models, from the original 2007 Kindle to the first‑generation Kindle Paperwhite and early Kindle Fire tablets. According to the company, owners will retain the ability to read books already stored on their devices, and their Amazon accounts will remain usable through mobile and desktop applications. However, a factory reset on the affected units will render them inoperable for new purchases, borrowing, or downloads. Amazon is offering discounts to encourage users to upgrade to newer hardware, acknowledging that many of the devices have been supported for 14‑18 years. The move has ignited a wave of criticism online, with users describing their still‑functional e‑readers as being reduced to "paperweights" and accusing the retailer of fostering large‑scale waste. Ugo Vallauri of the Restart Project—a UK‑based repair advocacy group—told the BBC that manufacturers often cite performance improvements when ending support, but this does not justify "soft‑bricking" millions of functional devices. He estimates the impact could affect roughly 2 million e‑readers, representing about 3 % of Kindle users, potentially creating more than 624 tons of e‑waste. Tech analyst Paolo Pescatore described the decision as "understandable from a security and support perspective," noting that the hardware of these older models was not designed for today's data‑intensive services. In summary, Amazon's phase‑out underscores the tension between extending product lifespans and keeping pace with rapid technological advancement, while raising environmental questions about the fate of legacy devices.

The debate over space exploration has sparked intense discussion, with critics arguing that the vast sums of money spent on it could be better used to address pressing global issues. The Artemis programme, with its $100bn budget, has been singled out as a prime example of such misallocation. This programme's cost could, for instance, fully fund the UN World Food Programme for 10 years, a global initiative that benefits over 150 million people annually in more than 120 countries.On the other hand, proponents of space exploration argue that it is crucial for humanity's long-term survival. They contend that as Earth faces environmental challenges, space could provide a necessary escape route. Moreover, the advancement of technology and knowledge gained through space exploration could have unforeseen benefits for human society.Critics also point out the short-sightedness of prioritizing space travel over solving Earth's problems, such as war and environmental destruction. They suggest that parenting-like responsibility should be applied to space exploration, implying that humanity should focus on solving its current issues before venturing further into space.However, supporters emphasize that space exploration represents a 'shining light of hope' for humanity's future, especially in a world threatened by autocrats and environmental crises. They argue that even small steps in space exploration are necessary for our long-term existence.Ultimately, the question of whether space exploration is worth the money and effort remains a complex and contentious issue. While some see it as a luxury we cannot afford, others believe it is an investment in our future survival.

A 47‑year‑old woman who had endured three life‑threatening autoimmune diseases for more than a decade is now living a near‑normal life after an experimental CAR‑T cell therapy reset her immune system at University Hospital Erlangen in Germany.Before the procedure she had exhausted nine different treatments with no lasting benefit, relying on daily blood transfusions and continuous anticoagulation to manage her illnesses.Within weeks of the infusion, doctors observed rapid improvement in all three conditions—a world‑first outcome. She has remained in treatment‑free remission for 14 months and has largely returned to everyday activities.Prof Fabian Müller, who led the team, called the speed and depth of the response “remarkable” and said the therapy “significantly improved her quality of life.” He emphasized that clinical trials are required to determine how durable the effect is and whether it can help other autoimmune patients.The patient suffered from three distinct disorders: autoimmune haemolytic anaemia (AIHA), where rogue immune cells destroy red blood cells; immune thrombocytopenia (ITP), which depletes platelets and raises bleeding risk; and antiphospholipid syndrome (APS), which promotes dangerous blood clots. All three stem from malfunctioning B‑cells.With no conventional options left, doctors turned to CAR‑T therapy, a technique that has revolutionised treatment for certain cancers. They harvested her white‑blood cells, isolated the T‑cells, engineered them to recognise the CD19 protein on B‑cells, and reinfused the modified cells.The engineered T‑cells swiftly eliminated the pathogenic B‑cells. She received her last blood transfusion a week after treatment and was able to perform routine tasks within two weeks. Follow‑up tests showed a reconstituted, healthy B‑cell population, suggesting an immune reset. The findings were published in the journal Med.She still exhibits a mildly low white‑cell count and slightly elevated liver enzymes, which researchers attribute to the cumulative impact of prior therapies rather than the CAR‑T product.Rheumatology expert Prof Ben Parker of Manchester University NHS Foundation Trust described the case as encouraging, noting that “the prolonged response off normal therapy suggests there has been an immune reset.” However, he warned that case reports alone cannot confirm efficacy and highlighted ongoing trials for lupus, myositis, multiple sclerosis, systemic sclerosis, vasculitis, and other autoimmune conditions.

As rising temperatures push snakes and humans into closer contact, the world faces an estimated 5.5 million snakebites each year, resulting in 138,000 deaths and 400,000 lasting disabilities. In response, a Wisconsin‑based amateur scientist has taken an extreme route to help solve the crisis.For almost 20 years, Tim Friede, a former window cleaner, allowed some of the planet’s most lethal snakes to bite him, accumulating over 200 intentional bites. His goal: to provoke his own immune system into producing antibodies that could be harvested for a near‑universal antivenom.The endeavor has been perilous. Friede survived a coma after being bitten by two cobras within an hour, endured anaphylactic shocks, lost tissue in a finger, and even had to cut necrotic muscle from his leg. Yet he persisted, eventually becoming immune to the inland taipan—the world’s most venomous snake, whose single bite can kill more than 100 people.In 2019, California biotech firm Centivax hired Friede to extract his antibodies. Early laboratory work showed that his serum can neutralise toxins from 19 elapid species, including cobras, mambas, taipans, coral snakes and kraits—roughly half of all venomous snakes worldwide.The next step is a veterinary trial in Australia, slated for later this year, before any human application. If successful, the antivenom could dramatically reduce the burden of snakebite in low‑income regions across Asia and Africa, where most victims live.Climate scientists warn that warming climates will expand snake habitats and increase human exposure, as illustrated by the recent surge of rattlesnake bites in California’s Ventura County. This amplifies the urgency for scalable, affordable antivenoms, especially as international aid budgets face cuts and manufacturing capacity remains insufficient.Friede’s unconventional path underscores a broader lesson: confronting emerging health threats may require bold, unconventional science, but the potential payoff—a life‑saving treatment for millions—could be transformative.

Korean fried chicken, also known as yangnyeom chicken, has become a global phenomenon, with a presence in over 60 countries and more than 1,800 stores worldwide.The dish, which originated in South Korea, was introduced by American soldiers after the Korean War. However, it wasn't until the 1980s that a Korean chicken shop owner, Yoon Jong-gye, developed a sweet and spicy recipe that made it distinctly Korean.The cultural breakthrough for Korean fried chicken came in 2014 with the Korean drama My Love from the Star, which became a sensation in China and triggered a surge in popularity for Korean chicken restaurants.Today, Korean fried chicken is the most popular Korean food among international consumers, according to a South Korean government survey. The dish has become a staple in many countries, with chimaek, the portmanteau meaning 'fried chicken and beer,' entering the Oxford English Dictionary.The success of Korean fried chicken can be attributed to its simplicity, technique, and adaptability. Korean chicken brands have expanded internationally, with many offering a range of recipes tailored to local tastes.At the heart of Korean fried chicken's success is its unique cooking technique, which involves double-frying the chicken to achieve extra crispiness. The batter, typically made with potato or corn starch, holds up well under the sauce, allowing it to stay crisp even after being boxed up for delivery.Prof Joo Young-ha, a cultural anthropologist, argues that Korean chicken's global success stems from its simplicity and universal appeal. 'Unlike pork, chicken crosses religious prohibition boundaries,' he says. 'And unlike kimchi, which is treated like a side dish, or bibimbap, which isn't immediately obvious as a dish, fried chicken is immediately recognizable as a meal.'