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The Lead: Biotech Barbie's Mission to Edit Human DNA Cathy Tie, a Canadian entrepreneur known as "Biotech Barbie," is pursuing a controversial mission to genetically modify embryos to prevent hereditary diseases, following in the footsteps of her ex-husband He Jiankui, who served prison time for creating the world's first gene-edited babies. Despite global bans on germline gene editing for reproductive purposes, Tie aims to conduct this work openly with regulatory approval and venture capital funding. The Technical Breakthrough: Gene Editing Made Accessible Since the invention of the Crispr-Cas9 gene editing tool in 2012, the technical process of altering DNA has become relatively straightforward. "The hardest thing about genetically engineering a baby is getting permission to do it; the technical part is not particularly complicated," the article explains. The process is compared to using "find, copy, cut and paste functions on a computer" and doesn't require extensive expertise in molecular biology. Germline gene editing—altering eggs, sperm, or early embryos—is particularly significant because changes are passed down to future generations, potentially altering human evolution permanently. This is why such procedures are banned in the UK, US, and China, with international agreement against research that could result in gene-edited babies. The Financial Landscape: Billionaires Investing in Genetic Engineering Money is flowing into human genetic engineering, with some of the world's richest men investing in companies pursuing similar goals. Preventive, a gene editing startup launched in October 2025 with the aim of "preventing disease before birth," has attracted investment from OpenAI's Sam Altman, his husband Oliver Mulherin, and Coinbase CEO Brian Armstrong. Armstrong has coined the term "the Gattaca stack"—referencing the dystopian film about a genetically engineered society—which includes technologies for "disease prevention, or enhancement" of babies. This suggests a growing interest not just in preventing diseases but in enhancing human traits. Preimplantation genetic testing (PGT), already common in the US fertility treatments, allows parents to "choose the embryo that best matches what you want," with companies like Nucleus Genomics advertising on subways with the tagline "Have your best baby." The Global Impact: A New Biological Arms Race? "There's a big geopolitical component to this," Tie states, referring to the growing interest in genetic engineering. China, where Tie was banned from entering, has already demonstrated what gene editing can do—Chinese researchers made the first edits to human embryos in 2015, and Tie's ex-husband He Jiankui created the first gene-edited babies, twin girls known as Lulu and Nana. Since his release from prison in 2022, He has become an unlikely social media star with close to 150,000 followers on X, making unrepentant posts about "designer babies" being "inevitable." Meanwhile, China's biotechnology ambitions have expanded, with Premier Li Qiang announcing new regulations emphasizing "the need to promote innovative development" and "accelerate R&D; and commercialization." In response to China's announcement, Tie posted: "Welcome to the dawn of the biological arms race." The Future Outlook: Inevitable Genetic Modification "Biology is a double-edged sword – it can be used for good, to heal people, or it can be used for bad," Tie explains. "Stopping this research will only drive bad actors to do it secretively. There is no way to stop this. This is inevitable. The only way to proceed is to do it openly and transparently." Tie named her first human gene-editing company the Manhattan Project, drawing a parallel between the nucleus of the atom and the nucleus of the cell. "In the 20th century, we understood the nucleus of the atom very well, and we learned some very difficult lessons via weapons and wars," she says. "I don't want to see the same happen with the second nucleus." Despite her declared commitment to openness, much of Tie's work remains shrouded in secrecy. Her first company, the Manhattan Project, has since shut down due to what she calls a "fundamental mistake" in choosing a co-founder. She has since launched Origin Genomics, continuing her pursuit of genetic modification of embryos.

A New Vision for Global ProsperityIn our increasingly dystopian world, the World Justice Report offers a utopian antidote by outlining how to build a prosperous, equitable world within safe planetary boundaries. This ambitious plan from the modern eco-socialist left presents a comprehensive vision for the future that could see the majority of people working less and earning more by the end of the century while keeping temperatures down and avoiding much of the current destruction of nature.The Core Principles of the Justice ReportThe report incorporates important concepts of "sufficiency" and "planetary habitability," addressing the fundamental question of how to reduce the material impact of economic activity—a topic long ignored by the traditional left. By widening the definition of prosperity and emphasizing "sufficiency," the report demonstrates that quality of life is more valuable than quantity of material goods, echoing ancient philosophies of a "golden mean" and Bhutan's concept of "gross national happiness."Challenging Economic OrthodoxyThomas Piketty, one of the coordinators of the report, argues that the ambition of the mega-rich has become unrealistic and undesirable. "Their new dream is to cover the entire planet with data centres," Piketty states, "This is their economic project for the world. But everybody can see that this is just going to increase the material footprint of our economy, that this is going to make global warming even worse."The Alternative to Techno-ExtractivismThe report stands in stark contrast to the far-right techno-extractivist vision currently being championed by the US president and his supporters in Silicon Valley, who are putting artificial intelligence ahead of renewable technology. In the quest for "energy dominance," the US is using tariffs and military power to widen markets for oil, gas and coal—a strategy that drives the world toward catastrophic levels of global heating and inequality.Bridging the Climate Science GapThe report fills a significant hole that has existed since the inception of the global climate science infrastructure in the 1990s. Robert Watson, a former chair of the UN Intergovernmental Panel on Climate Change, noted that if he could go back in time, he would have added more social scientists to the climate discussion. The "pure scientists" from physics and chemistry initially believed data alone would persuade governments to act, but later wished they had taken more account of social dynamics, economics, politics and psychology.Overcoming the Green Growth IllusionThe report challenges what Piketty calls the "illusion of classless ecology" or the "green growth illusion" that everything will be solved by producing more without worrying about distribution, sufficiency, or structural transformation. This illusion, he argues, has made green policy unpopular for many lower and middle-income voters by ignoring the social dimensions of climate action.The Path to Cultural Transformation"Sufficiency does not mean degrowth," explains Cornelia Mohren, Environmental Coordinator of the World Inequality Lab. "It is about less working hours, a different composition of consumption, and more health and education." The authors emphasize that they don't want to force people to change their lifestyles but rather initiate a cultural shift in how society perceives the good life.A Future Forged in CrisisPiketty acknowledges that crises are inevitable but argues it's important to initiate debates now so that alternatives are already in people's minds and will become more palatable in the future. "People need to get accustomed to the fact that big change will happen in any case," he states. "We are not in a situation where things can just continue as they are forever." The report remains open for suggestions and revisions, inviting global participation in shaping this alternative vision for our shared future.

The LeadCorridors have long been more than just passageways in cinema—they are narrative spaces that build tension, create atmosphere, and advance storytelling. The Guardian has compiled a definitive ranking of the 20 most memorable corridors in film history, showcasing how these seemingly simple spaces have become iconic elements of cinematic language.The Art of Cinematic CorridorsFrom the claustrophobic hallways of horror films to the dystopian passageways of science fiction, corridors have served as powerful storytelling devices across genres. The ranking includes entries from 1979 to 2011, with films like "The Thing" (1982), "Brazil" (1985), and "The Raid: Redemption" (2011) demonstrating how directors use these spaces to create memorable sequences.Ranking Criteria and Notable MentionsThe selection process appears to prioritize corridors that have become iconic through their visual impact, narrative significance, and ability to evoke emotion. Notable mentions include:The marble corridor in "Phantasm" (1979), which became a source of nightmares for viewersThe endless grey passageway in "Brazil" (1985), created using forced perspective in a disused flour millThe baroque corridors of "Last Year at Marienbad" (1961), which create a uniquely spooky ambienceThe modern corridor chase in "The Red Queen Kills Seven Times" (1972), featuring a figure in a red cloakThe Impact of Corridors on FilmmakingThese cinematic corridors have influenced generations of filmmakers and continue to be referenced in contemporary cinema. The ranking reveals how directors have mastered the use of confined spaces to build suspense, create visual symbolism, and advance character development. Horror filmmakers, in particular, have long recognized the corridor's potential for terror, using its linear nature to create anticipation and dread.The Future of Corridor Scenes in CinemaAs filmmaking techniques evolve, the corridor continues to be a vital space for cinematic storytelling. With advances in virtual production and immersive technologies, future corridor scenes may push the boundaries of visual storytelling even further. The enduring appeal of these spaces suggests that corridors will remain essential tools for filmmakers seeking to create memorable, tension-filled sequences that resonate with audiences.

The LeadA novel featuring a protagonist whose job is taken by AI has won the Climate fiction prize. Hum by Helen Phillips, the American writer's third novel, explores themes of technological displacement and the commodification of nature in a dystopian future.The Disneyfication of Nature in LiteratureHum is about a woman, May, who loses her job to a "hum" of the title – a humanoid robot. Struggling to find work, she becomes a guinea pig for an experimental injection that alters her face so it can't be recognised by surveillance. When she gets paid for it, she splashes out on family passes to the Botanical Garden, the last remaining green space in her city. There, things take a turn for the worse.The Climate Fiction Prize RecognitionThe prize, worth £10,000, was first awarded last year to Abi Daré for And So I Roar, the follow-up to her bestselling debut The Girl with the Louding Voice. This year's judging panel was chaired by Guardian theatre critic and former literary editor of the Independent, Arifa Akbar. Alongside Kit de Waal and Friederike Otto on the panel were author Jessie Greengrass and book influencer Simon Savidge.Judges' Perspectives on the NovelJudge and writer Kit de Waal described Phillips's book as being about the "Disneyfication of nature … turning nature into a rare place that we have to pay to see". Fellow judge and climate scientist Friederike Otto added that it "tackles the central reason that nothing is done about the climate crisis – privilege", while writer Daisy Hildyard described it as "mesmerising and scary".The Author's InspirationPhillips was inspired to write the book after walking home from work one day and having the thought that she needed to buy dishcloths, before opening her computer at home and finding that dishcloths were being advertised to her. "That eerie feeling stuck with me, and I started to think about what worst-case scenarios might arise from surveillance by an algorithm."Impact on Climate AwarenessHum "helps us connect with what really matters and stops us from sleepwalking into an inevitable dystopia", said Lucy Stone, CEO of Climate Spring, which funds the prize. "In the novel, the machines themselves start to question the insane volume of advertising and the consumer treadmill, and then show the family that there are multiple different futures lying ahead of them."Future RecognitionPhillips will appear at Hay festival to discuss the book on Saturday 30 May. Alongside Phillips on this year's shortlist were Madeleine Thien for The Book of Records, Robbie Arnott for Dusk, Keshava Guha for The Tiger's Share, Susanna Kwan for Awake in the Floating City and Maria Reva for Endling.

Five‑Day Berlin Blackout: A Sabotage UnveiledOn 3 January 2026, a fire set on five high‑voltage cables under a bridge over the Teltow Canal plunged large parts of Berlin into darkness for five days, marking the longest outage since World War II. The attack was claimed by a self‑styled “Volcano Group”, linking the sabotage to broader anti‑fossil‑fuel activism. Arson on High‑Voltage Cables Triggers Citywide OutageApproximately 12 km from the Immanuel Hospital, the cables—each 10 cm thick and supplying power to about 45,000 homes, 2,200 businesses and four hospitals—were set ablaze. The fire was captured on video by Stromnetz Berlin, the city’s state‑owned grid operator, showing the cables burning above a pile of debris. Scale of the Outage: Numbers and Immediate Consequences10,000 homes restored electricity by the next day.35,000 homes remained without power for the full five days.Hospitals relied on emergency generators; Immanuel Hospital’s diesel tank held 3,000 L and burned ≈550 L/day.Hospitals faced cancelled surgeries, heating failures, and patient evacuations. Human Toll and Hospital Operations Under StrainTechnicians at Immanuel Hospital rerouted power to gas pumps, averting a heating crisis. At the nearby Hubertus Hospital, director Michael Schmidt evacuated 150 patients and postponed operations. Residents endured a “dystopian” atmosphere, with makeshift community support emerging around hospital canteens. Future Security Measures and Threat LandscapeThe confession, posted on left‑wing platforms, framed the act as “shutting down fossil fuel power stations”. The Volcano Group has a history of at least seven attacks since 2011, often referencing Icelandic volcanoes. Authorities now face pressure to harden vulnerable infrastructure points—especially above‑ground crossings like the Teltow Canal bridge—and to monitor anonymous activist channels for similar threats.

The Dystopian Vision of 2028 Los AngelesBrimming with indelible images, Charlotte Zhang's brilliant debut locates the roots of a dystopian future in the here and now. Set around the 2028 Summer Olympics, the film imagines a Los Angeles gripped by paranoia and conspiracies; and a livestock disease has led to a ban on all meat production, leaving the main source of protein distribution – powdered insects – in the control of a megacorporation called Ootheca Inc. Ironically enough, a cockroach infestation has taken over several local neighbourhoods, making Ootheca's monopolising greed even more insidious.A Human Story of Survival Amid Corporate ControlAll of this might sound pretty out there, yet the heart of Tycoon is a deeply human story of survival. Both hustlers up for any challenge, Lito (Miguel Padilla-Juarez) and Jay (Jon Lawrence Reyes) take advantage of the widespread chaos to embark on a series of petty crimes, including breaking into an Ootheca trailer to steal boxes of the precious protein powder. Their escapades are dynamically rendered on a variety of formats including handheld DV camera and Super 8, as well as Xerox art. But compared to other film-makers who favour this DIY style, Zhang is beautifully attentive to blocking and composition. Scenes of house parties, twilight rides against the setting sun, or high-rev street drifting harmonise into a stunning city symphony, in which a visual rhythm gradually emerges from disorder.Political Implications in a Corporate-Dominated WorldBeneath the seemingly casual tone of the visuals, there are also serious political implications. As Latino men living in a time of state-sanctioned racial violence, Lito and Jay are enfolded in economic precarity and constant surveillance. That they choose to game the system rather than waiting to be squashed by it – like Ootheca's crushed insects – is wonderfully empowering. Zhang occasionally makes explicit these political allusions by way of text intertitles, which sometimes feel a little awkward; still, when is a better time to deliver a manifesto than in one's first film?Where to Experience This Visionary DebutTycoon is at the ICA, London from 22 May.

The LeadBump into one of these scarecrows at night and you'd be forgiven for running a mile. But stick around to listen to this hay-laden gang of crop-protector castaways, who no longer have crops to protect nor birds to scare thanks to the climate crisis, and you'll see they have only good intentions.The Dystopian VisionThe sensorily ambitious Farm Fatale joins five scarecrows with faces of melted plastic and voices of children swallowed by machines in the artificial studio of their pirate radio station. It is set in the near future, when the air is hard to breathe and birdsong is recorded. The only people getting by are the industrial farmers capitalising on the ruin of others. When the scarecrows interview a bee, with a microphone charmingly taped to a pitchfork, the little creature is described as one of the last in Europe.The Creative ProcessInfused with a sense of ideas tossed like freshly mixed compost, this wistful French production was first created in Germany and is performed in English. Director Philippe Quesne, who curates decades-long collaborations with his actors, takes a sociologist's eye to his work, relishing in watching what a group of oddball characters in an enclosed space will do.The Visual DesignThe sprawling show's first half is deliciously freaky and surprisingly sweet, setting up the rules of its own game as we learn why these scarecrows had to leave their independent farms and how their radio station is fuelling hope and protest. But as it progresses, on the bleached set of white plastic and hay bales designed with Nicole Marianna Wytyczak, it gets distracted by its own imagination.The Narrative ChallengesThe story becomes restless, turning at one point to a sci-fi concert for eggs (a recurring motif in the director's work), then to a violent vigilante attack. Neither set piece is as rooted in its own worldbuilding nor as absurdly entertaining as the rest.The Thematic ImpactAs it makes its meandering case for art as salvation and farms as the lifeblood of humanity, and the scarecrows karaoke a cover of It's Not Easy Bein' Green, you begin to feel a little like you're watching an overexcited improv troupe. But with an extraordinary aesthetic and a committed cast – Gaëtan Vourc'h's gormless activist is a particular treat in his ebullient strangeness – these droll effigies are excellent company in their rejection of despair.

The Return of Smoggie QueensPhil Dunning's Middlesbrough-set LGBTQ+ comedy returns to BBC Three tonight at 10pm, promising more endearingly lo-fi hijinks at Keith's World of Carpets. The gang are throwing a coming-out party for Stewart, but after Keith busts out his terrifying homebrew ("fermented for 37 years"), everything gets a bit psychedelic. The timing isn't great for Dickie (Dunning) when his ex turns up. While the show never quite manages to be uproarious, viewers can expect to snigger happily throughout.Other Notable TV TonightBeyond Smoggie Queens, tonight's television lineup offers a diverse range of programming:Unreported World (7.30pm, Channel 4) - Explores faith-based treatments in the Philippines amid soaring healthcare costsHidden Treasures of the National Trust (9pm, BBC Two) - A literary-themed opener exploring Agatha Christie's Greenway Estate in DevonHacks (9pm, Sky Atlantic) - Final season focuses on legacy and the stories celebrities tell about themselvesFirst Dates (10pm, Channel 4) - Fred Sirieix hosts another batch of hopeful romanticsSt Denis Medical (10.40pm, BBC One) - Nurse Pam takes temporary charge with surprising consequencesThe Running Man (7am, 8pm, Sky Cinema Premiere) - Edgar Wright's new adaptation of Stephen King's dystopian thrillerThe Cultural Significance of LGBTQ+ RepresentationSmoggie Queens represents an important example of authentic LGBTQ+ representation in mainstream television. The show's setting in Middlesbrough, a working-class northern English town, provides a refreshing counterpoint to the more common metropolitan portrayals of LGBTQ+ life. Its return to BBC Three demonstrates the channel's continued commitment to diverse programming that reflects the full spectrum of British experience.The Evolution of Drag Comedy on TelevisionDrag comedy has evolved significantly from its early appearances on television, moving from novelty acts to nuanced character studies. Shows like Smoggie Queens contribute to this evolution by placing drag performers at the center of narratives that explore identity, community, and belonging. The show's lo-fi aesthetic and focus on character-driven comedy rather than spectacle represents a maturation of the genre.The Future of Regional Comedy ProgrammingThe return of Smoggie Queens highlights a growing trend toward regionally specific comedy programming that moves beyond London-centric narratives. By setting the show in Middlesbrough and embracing local dialects, cultural references, and landscapes, the program offers viewers an authentic representation of northern English life. This approach not only provides refreshing diversity but also challenges the traditional power dynamics in British television production.

The Film's Premise A new short film, Vitória Régia (Amazon Water Lily), has imagined a future where a far-right coup in Brazil succeeds, and the Amazon rainforest is surrendered to the United States. The film depicts a dystopian scenario where Brazilian democracy is annihilated, and the military takes power. A Nightmarish Scenario The film's plot centers around a scenario where Jair Bolsonaro's plot to seize power after the 2022 election is successful. The military takes control, censoring the media, purging ideological 'deviants,' and transferring control of the Amazon to Washington in exchange for its support of the coup. The Data Analysis The film highlights the potential consequences of such a coup, including the exploitation of the Amazon's natural resources by US interests. The film's director, Denis Kamioka, noted that the film was shot in March 2025, nearly a year before Donald Trump's administration took a similar stance in Venezuela. The Impact Analysis The film's lead actor, Alice Braga, said that the film became 'almost a documentary' given the similarities between the film's plot and real-life events. The film aims to draw attention to the threats facing Brazil's Indigenous peoples and their centuries-long quest to defend their traditional lands. The Prediction The film's creators hope that it will serve as a warning about the dangers of far-right extremism and the importance of protecting democracy and the environment. With Bolsonaro's politician son Flávio poised to challenge the leftwing incumbent, Luiz Inácio Lula da Silva, for the presidency, the film's message is more relevant than ever.