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The Lead Doctors, scientists, and researchers shared new research about ways to tackle cancer at the 2026 American Society of Clinical Oncology (Asco) annual meeting, the world's largest cancer conference. Breakthroughs in Cancer Treatment The event in Chicago, attended by 40,000 health professionals, featured more than 200 sessions and 2,700 poster presentations on this year's theme, “the science and practice of translation: improving cancer outcomes worldwide”. Smart Drugs in Cancer Treatment Researchers have developed a smart drug that stops cancer cells hiding. The experimental tablet, GRWD5769, can help shrink tumours by at least 30% in six of the world’s most common forms of the disease, delegates in Chicago were told. 26 of 83 patients with cervical, bladder, liver, bowel, lung or head and neck cancers who were given GRWD5769 alongside cemiplimab had tumour reductions of at least 30%. 15 had tumour reductions of at least 30%. A Daily Pill for Pancreatic Cancer A pill that doubles survival time in patients with pancreatic cancer was presented at the conference. In a trial of 500 patients, all of whom had pancreatic cancer that had spread, the pill, daraxonrasib, doubled survival time, with fewer side-effects compared with chemotherapy. Patients who took the drug lived substantially longer, for an average of 13.2 months, compared with 6.6 to 6.7 months for patients who had chemotherapy. Safely Skipping Some Treatments Some patients can safely skip some treatments, according to research presented at the conference. A genomic test could pave the way for a new era of personalised medicine, enabling doctors to determine which patients can safely skip chemotherapy. The Optima trial, led by University College London, followed 4,000 patients with newly diagnosed breast cancer in the UK, Norway, Sweden, Australia, New Zealand and Thailand. Those with a low score on the genomic test could be treated safely with hormone therapy alone. The Future of Cancer Treatment Urgent action is required to cope with rising cancer cases. The world faces a cancer workforce crisis, experts said, with a shortage of 100 million staff expected by 2050 when 100,000 people will be being diagnosed every day. A 21% increase in cancer incidence is predicted, according to a report presented at the conference. The rate is set to rise from 165 per 100,000 people in 2025 to 200 per 100,000 in 2050.

The Rollercoaster of Graham Potter’s Managerial CareerIn a candid interview, the 51‑year‑old English coach admits that “you’ve got to face the bad stuff” after a series of highs and lows that saw him leave Brighton’s stability, endure a seven‑month stint at Chelsea, and later struggle at West Ham before finding a new purpose with the Sweden national team. From Brighton Stability to Chelsea’s Short‑Lived TenurePotter departed the comfort of Brighton in September 2022 to take over at Chelsea. The move lasted only seven months, ending in a mutual parting as the club failed to meet expectations. West Ham Struggles: Six Wins from Twenty‑Five MatchesGames managed: 25Victories: 6Result: Dismissed in September 2025 after a poor start to the seasonThe spell at West Ham was described by Potter as “lost in dysfunction”, with the team unable to translate his ideas into results. Sweden’s World‑Cup Revival Under Potter’s Swedish‑Style EthosAfter his club setbacks, Potter accepted a short‑term role with Sweden in October 2025. The team, previously stuck in a “doldrums” qualifying group, earned a playoff spot via Nations League performance. Key moments included:Viktor Gyökeres’ hat‑trick in the 3‑1 semi‑final win over UkraineGyökeres’ 88th‑minute winner in the 3‑2 playoff final against PolandThese victories secured Sweden’s place at the 2026 World Cup, and Potter’s contract was subsequently extended to 2030. He says he “feels very Swedish” and notes that two of his children were born in Sweden. Looking Ahead: Potter’s Contract to 2030 and Sweden’s Group‑F ChallengeSweden will open the tournament against Tunisia in Monterrey on 14 June 2026, then face Japan, the Netherlands and Tunisia in Group F. Potter highlights the importance of set‑pieces and squad harmony, especially with key players like Alexander Isak and Gyökeres available, while coping with the injury to Dejan Kulusevski.With a contract secured until 2030, Potter’s “Swedish” methodology will be tested on football’s biggest stage, offering a chance to rewrite his managerial narrative after the club disappointments.

Iraq has clinched a historic spot at the 2026 World Cup, becoming the final nation to qualify and ending a 40‑year absence from football’s biggest stage. The Epic Journey to Mexico and Qualification Twenty hours on a bus, a charter plane out of the Middle East, and a one‑off game carrying the expectations of 48 million people defined Iraq’s road to the tournament. After a two‑year, 21‑match qualification marathon, the Lions of Mesopotamia travelled overland to Jordan, endured a 24‑hour flight delay, and finally landed in Monterrey for the inter‑continental playoff against Bolivia. Coach Graham Arnold gave his squad three days to recover before the decisive match, insisting they “don’t use it as an excuse.” The plan worked: a 2‑1 victory, sealed by a corner‑kick goal from 24‑year‑old forward Ali Al‑Hamadi, booked Iraq’s place at the World Cup for the first time since 1986. Numbers Behind Iraq’s Historic Qualification 21 matches played over more than two years 48 million Iraqi fans cheering the campaign Travel itinerary: 20‑hour bus ride → charter plane → 24‑hour flight delay → 3‑day recovery period Playoff result: Iraq 2 – Bolivia 1 First World Cup goal scorer: Ali Al‑Hamadi (on loan at Luton Town) What Iraq’s Return Means for Middle‑East Football The qualification marks a symbolic victory for a nation scarred by decades of conflict, sanctions and political instability. Football has become a “vehicle for happiness” for Iraqis, offering a rare moment of unity and pride. The success also revives the legacy of the 2007 Asian Cup triumph, reminding the region that Iraqi football can still compete on the continental stage. Beyond national morale, the achievement may inspire investment in grassroots programs across the Middle East, encouraging other war‑torn nations to view sport as a pathway to global recognition. Looking Ahead: Iraq’s Group‑of‑Death Challenge and Prospects With only a short preparation window, the squad will train in Spain and face friendlies against Spain and Andorra before heading to the United States. Drawn in a “group of death” with France, Norway (featuring Erling Haaland) and Senegal, Iraq’s path is steep. Arnold’s experience—guiding Australia to the round of 16 at Qatar 2022—provides tactical know‑how, but success will hinge on the team’s “mindset of shocking the world.” Midfielder Aimar Sher, born in Iraq but raised in Sweden, epitomises the blend of diaspora talent and home‑grown determination that could fuel an upset. If the Lions can translate their fighting spirit into disciplined performances, they may not only spoil a party but also rewrite the narrative of Middle‑East football on the world stage.

Liverpool's Swift Managerial ChangeRichard Hughes and Michael Edwards have acted with decisiveness and a clear sense of what Liverpool's difficult situation demanded in switching head coaches within six days, although the appointment of Andoni Iraola removes just one layer of uncertainty from Anfield. Several others remain, including their roles in leading Liverpool's recovery alongside Arne Slot's successor.With supporters turning against Slot's football and more players liking Mohamed Salah's critical social media post than wishing the Dutchman well following his sacking, Liverpool could not allow disillusionment to fester and needed to move fast. Sporting director Hughes and Edwards, chief executive of football for the club's owner Fenway Sports Group, have delivered.Iraola's Appointment: Style and PhilosophyIn Iraola, who was coveted by Milan, Bayer Leverkusen and Crystal Palace after improving Bournemouth in each of his three seasons on the south coast, those in charge of football operations at Liverpool have hired a coach who promises a version of the aggressive attacking style that captivated the Kop under Jürgen Klopp. But winning is what captivates Anfield most of all and there is much more to the appointment of Iraola than style of play.Liverpool's new head coach has demonstrated a flair for improving individual players and handling disruption with minimal fuss. Slot may have lost his way on all counts, but still delivered Champions League qualification in the most trying circumstances and under a most unforgiving spotlight.Liverpool's Investment and Performance DeclineThe urgency behind the move for Iraola was not only a reaction to external pressures and the despondency that had set in at Anfield over the final weeks of last season. Several attractive clubs are in the market for a new manager before the World Cup and there is a limited pool of talent available.With the Basque holding talks with Leverkusen and Milan, and Liverpool's powerbrokers convinced of his suitability and ability, FSG needed to sign off on their recommendations quickly. The World Cup will disrupt Iraola's first pre-season and there is much to be done to turn the trajectory of a team in decline.New signings are the obvious place to start. Slot believed the addition of two wingers this summer would catapult Liverpool back to the levels of his title-winning campaign, finally filling the voids left by Luis Díaz's departure and Salah's dramatic drop in form. Liverpool agree with their former head coach on that score and two wingers remain their priority.The Challenge of Managing at AnfieldBournemouth operate in a completely different environment. Iraola surviving at the Vitality Stadium after a nine-game winless start to his Premier League career is testament to that. "We didn't start well and, probably, you were thinking: 'Who the fuck is this guy?'" Iraola joked at his Bournemouth farewell.Anfield would not be pondering that question during a nine-game winless run but screaming it at those responsible. Unwavering support for a Liverpool manager is not guaranteed, as Slot discovered 13 months after delivering the title in his debut season and having faced unprecedented challenges in his second.But Iraola has been hired because Liverpool also firmly believe he can get the best out of players already in the building. The judgment of Hughes and Edwards is likely to stand or fall by this conviction. Liverpool's reputation for astute trading and forward thinking, well established in the Klopp/Edwards era, has taken a battering after last summer's record investment of almost £450m yielded dismal results.Iraola's Path to Liverpool's RecoveryLiverpool remain convinced they acquired talent that can deliver the biggest prizes. The eyes on last season say differently, although there is substance to the argument that Slot struggled to find the best position for Florian Wirtz or play to the strengths of Alexander Isak. Liverpool's former head coach could respond with an injury list that restricted Isak, Wirtz and Hugo Ekitiké to less than two hours together on the same pitch last season.Isak appeared ill-suited to Liverpool on the few occasions he was match fit but a more dynamic approach under Iraola, who wants the ball released into his forwards as early as possible, should make the Sweden international more effective. Wirtz, clearly gifted but too often on the periphery in his debut Liverpool campaign, should also benefit from the shift in style plus the addition of two fast wingers.Iraola's work with defenders is another part of his appeal to Liverpool. At Bournemouth he coached Illia Zabarnyi, Dean Huijsen and Milos Kerkez into talents worthy of big money moves to Paris Saint-Germain, Real Madrid and Liverpool respectively. Not one has had the same impact since leaving the Vitality Stadium.

The LeadIran were one of the first teams to secure qualification for the 2026 World Cup and, compared to previous campaigns, they had a relatively smooth path to the tournament. However, preparing the team for the competition has been anything but easy, with geopolitical conflicts threatening their participation.Tactical Flexibility Amidst Geopolitical ChallengesIran's conflicts with the US and Israel threw their involvement at the World Cup into serious doubt – all three of their group games take place in the US. Nevertheless, in their two friendlies in March against Nigeria and Costa Rica, Iran showed that they have different plans in mind for the World Cup. In the first match against Nigeria, they lined up in a 3-6-1 formation – a setup described as the team's "defensive plan B", likely designed for the group meeting with Belgium. In the second game against Costa Rica, Ghalenoei used a 4-4-2 formation, indicating that he intends to shift tactics depending on the opponent. The primary system remains 4-2-3-1, which Iran used in most of qualifying.Group Stage Fixtures and Strategic AdjustmentsIran will face New Zealand on June 15 in Los Angeles, Belgium on June 21 in Los Angeles, and Egypt on June 26 in Seattle. Despite the problems and controversies surrounding the national team, who moved their World Cup base camp from the US to Mexico just weeks before the tournament, manager Amir Ghalenoei still believes his side are capable of achieving something special. "We've had many problems recently, but the players tried their best and made sacrifices. They worked so hard [through qualification] and sacrificed a lot, so it is my job to thank them. They can do something epic in the World Cup."The Coach's Redemption MissionAmir Ghalenoei was a diminutive midfielder who played mainly for Esteghlal, one of Tehran's two biggest clubs. As a coach, Ghalenoei went on to become one of the most decorated managers in Iran, although his aggressive personality has prevented him from becoming universally popular. This is his second spell in charge of the national team. He first took over after the 2006 World Cup but was dismissed following Iran's elimination from the 2007 AFC Asian Cup – an episode he still recalls bitterly. Success this summer would give Ghalenoei an opportunity to settle old scores with his longtime critics.Captain Mehdi Taremi: Iran's Key AttackerMehdi Taremi has never truly been a fan favourite, but there is no doubt that if Iran are to achieve something significant at the World Cup, their hopes will rest on the form of a player who has delivered consistently for Porto, Inter, and Olympiakos. Having spent several years competing at the highest level in Europe, Taremi has developed confidence and authority, to the point that he is now influential in the team's internal decisions as well. He is a hard-working striker who also contributes defensively. His greatest strength lies in making runs in behind the opposition's defence and finding himself one-on-one with the goalkeeper.Rising Star: Mehdi Ghayedi's Potential ImpactMany in Iran expected Mehdi Ghayedi to develop into a major star, but controversy and off-field distractions seem to have followed him everywhere. So far he has failed to achieve the level of consistency and continuity that had been expected of him but he is only 27 and should be in his peak years. The lightning-fast Al-Nasr (UAE) winger could, in fact, become Ghalenoei's surprise weapon in North America. With his dazzling dribbling skills and precise finishing, Ghayedi is capable of producing eye-catching moments. After spending some time sidelined through injury, he marked his return to the national team with a stunning goal against Costa Rica in March.The Unsung Hero: Saman Ghoddos' VersatilitySince making his debut almost a decade ago, Saman Ghoddos has been a reliable, consistent member of the Iran squad. However, since he has never played for an Iranian club, he has not benefited from the traditional support of club fans, and as a result, has received less media attention. Nevertheless, thanks to his good character and professionalism, the former Brentford player – who can play almost anywhere on the pitch – is a well-liked figure within the team. Born in Malmö, Sweden, he left the Premier League for Kalba in the UAE in 2024.Probable Starting XI and Key AbsencesA few players can feel certain of their place in the starting lineup regardless of the formation. Alireza Beiranvand will be Iran's first-choice goalkeeper for a third consecutive World Cup. Shojae Khalilzadeh is the only centre-back guaranteed a starting spot, while Saeid Ezatolahi, if fully fit, is the undisputed No 6 in midfield. Up front, whether Iran play with one striker or two, Mehdi Taremi – wearing the captain's armband – will lead the line. Another star forward, Sardar Azmoun, has been left out. He is a divisive figure in Iran after the publication of photos with the ruler of the United Arab Emirates, who supported the US and Israel during the war.

The World Cup 2026 KickoffThe FIFA World Cup 2026 is set to begin on June 11 across North America with 48 teams competing over 39 days. The tournament will feature star players like Messi and Ronaldo and culminate in the final on July 19.North America's Historic TournamentFrom superstars Lionel Messi, Cristiano Ronaldo, Kylian Mbappe and Harry Kane to young guns such as Lamine Yamal, Arda Guler, Yan Diomande and more, football's brightest talents will assemble across the United States, Canada and Mexico. This marks the first time the World Cup will be hosted by three nations, expanding to 48 teams from the previous 32.Key Tournament DatesJune 11: Mexico vs South Africa – opening game of the 2026 World Cup in Mexico CityJune 12: Canada vs Bosnia and Herzegovina, USA vs Paraguay – opening matches of the other cohostsJune 14: Germany vs Curacao – Curacao become the smallest nation to play at a World CupJune 15: Spain vs Cape Verde – Cape Verde make their World Cup debutJune 16: Argentina vs Algeria, Austria vs Jordan – Argentina begin their title defence, and Lionel Messi starts his sixth World Cup campaign; Jordan play their first World Cup matchJune 17: Portugal vs Democratic Republic of the Congo, Uzbekistan vs Colombia – Portugal's Cristiano Ronaldo makes his sixth World Cup appearance; Uzbekistan play at a World Cup for the first timeJune 27: Group stage endsJune 28-July 3: round of 32July 4-7: round of 16July 9-11: quarterfinalsJuly 14-15: semifinalsJuly 18: bronze matchJuly 19: World Cup finalMust-See Group Stage MatchesIn order of their dates, here are some of the most anticipated group stage matchups:June 13: Brazil vs Morocco (Group C)June 14: Netherlands vs Japan (Group F)June 16: France vs Senegal (Group I)June 17: England vs Croatia (Group L)June 18: Mexico vs South Korea (Group A)June 20: Germany vs Ivory Coast (Group E)June 20: Netherlands vs Sweden (Group F)June 22: Norway vs Senegal (Group I)June 22: Argentina vs Austria (Group J)June 24: South Africa vs South Korea (Group A)June 25: Japan vs Sweden (Group F)June 26: Norway vs France (Group I)June 26: Uruguay vs Spain (Group H)June 27: Colombia vs Portugal (Group K)Global Impact and LegacyThe expanded format and three-nation hosting arrangement represents a significant shift in how the World Cup is organized and presented. This tournament will test FIFA's ability to manage logistics across multiple time zones and cultural contexts while maintaining the tournament's prestige and competitive integrity.The Future of Football's Premier EventAs football continues to evolve globally, the 2026 World Cup sets new precedents for scale and accessibility. The tournament's success will likely influence future expansions and hosting models, potentially establishing a new standard for mega sporting events in the 21st century.

The LeadTunisia is preparing for the 2026 World Cup with a fresh approach, having qualified without conceding a single goal in 10 matches. The North African nation has undergone significant changes, with new leadership and a focus on rebuilding around young talent as they prepare to face Sweden, Japan, and Netherlands in Group F.Coaching Transition and Tactical ShiftTunisia's qualification campaign was marked by instability, with three different coaches leading the team: Jalel Kadri, Montasser Louhichi, and Sami Trabelsi. The current manager, Sabri Lamouchi, took charge after Tunisia's elimination from the Africa Cup of Nations in January. Lamouchi's appointment carries special significance as he came close to representing Tunisia in 1993 but ultimately chose France, a painful memory for supporters. Since taking charge, Lamouchi has emphasized rebuilding around young players and has limited the squad to just three goalkeepers, addressing a controversy that arose when Tunisia took four to Qatar in 2022.Key Players and New FacesThe team's transformation is evident in its personnel. Hannibal Mejbri has emerged as the face of this national team, wearing the iconic No. 10 shirt previously held by Wahbi Khazri. After struggling to establish himself at Manchester United, the midfielder has flourished at Burnley and is now the first name on the teamsheet. Another rising star is 22-year-old attacking midfielder Ismaël Gharbi, developed at Paris Saint-Germain and now on loan at Augsburg. Despite limited playing time at his club, Lamouchi's faith in him has earned him a place in the World Cup squad.Tactical Approaches and FormationLamouchi has experimented with different formations during his tenure, using a 4-3-3 system against Haiti and a 4-2-3-1 against Canada. The flexibility in approach suggests he will adapt his tactics based on opponents at the World Cup. The team's defensive strength during qualification—conceding no goals—indicates a solid foundation regardless of the specific formation chosen for each match.Group Stage ChallengesTunisia faces a challenging Group F that includes Sweden, Japan, and Netherlands. Their fixtures will see them play in Monterrey against Sweden (June 14) and Japan (June 20), before concluding in Kansas City against the Netherlands (June 25). The geographical spread of venues presents logistical challenges for both the team and supporters traveling from North Africa.Fan Expectations and SupportTunisian fans are expected to provide passionate support despite the significant cost of traveling to the United States and Mexico. The supporters have developed a reputation for being enthusiastic ambassadors for their country, with no history of violence at recent tournaments. Their presence will be crucial in creating a home-away-from-home atmosphere for the team during their matches.Future ProspectsWhile Lamouchi has not set specific World Cup objectives in his contract, targets for the next Africa Cup of Nations have been clearly defined. The focus on youth development suggests Tunisia is building for sustained success beyond 2026, with the current squad representing a transition between generations. The blend of experienced leadership and emerging talent positions the team to potentially exceed expectations on the world stage.

Sweden secured their 2026 World Cup berth in a thrilling 3‑2 playoff victory over Poland, a turnaround driven by new coach Graham Potter and striker Viktor Gyökeres. With a challenging Group F draw and several injury concerns, the Swedes head to North America hoping the "Potter effect" can carry them beyond the group stage.The Potter Revival: Coaching TurnaroundAfter a disastrous qualifying start under Jon Dahl Tomasson (one point from four games), the Swedish FA sacked the Dane in October 2025 and appointed Graham Potter. Potter, famed for lifting Östersund from the fourth tier to Europa League glory, reinstated a disciplined defensive shape – initially a back‑four, then a pragmatic 5‑3‑2 in the playoffs – and emphasized swift counter‑attacks. His philosophy restored confidence, culminating in a 3‑1 semi‑final win over Ukraine and the decisive 3‑2 final against Poland.Group F Fixture Breakdown and Stats14 June: Sweden vs Tunisia – Monterrey, 20:00 local (03:00 BST, 12:00 AEST)20 June: Sweden vs Netherlands – Houston, 12:00 local (18:00 BST, 03:00 AEST)25 June: Sweden vs Japan – Dallas, 18:00 local (00:00 BST, 09:00 AEST)Sweden entered the tournament with six goals scored in the two‑leg playoff, four of which came from Gyökeres. The team’s defensive record improved to conceding only one goal across the playoff ties.Strategic Implications for Sweden’s World Cup CampaignThe shift to a compact defence and rapid transitions suits the physical demands of North American venues. However, the squad faces notable absences: captain Dejan Kulusevski is sidelined with injury, and striker Alexander Isak remains a fitness question after a mixed start at Liverpool. Depth will be tested against technically adept Netherlands and a disciplined Japanese side.Looking Ahead: Sweden’s Prospects in North AmericaIf Potter can maintain the defensive rigidity and harness Gyökeres’s goal‑mouth, Sweden could realistically target a knockout‑stage berth. Emerging talents such as Gustaf Lagerbielke and midfield anchor Jesper Karlström may provide the extra spark needed against tougher opponents. The next few weeks will reveal whether the "Potter effect" can translate into a historic World Cup run.

Koeman's Tactical Dilemma Amid Injury CrisisRonald Koeman faces arguably his most challenging managerial stint as he prepares the Netherlands for the 2026 World Cup. The Dutch head coach, known for his perfectionism and attacking football philosophy, has been forced to reconsider his options due to an unprecedented injury list that has sidelined nearly half of his preferred starting XI.Xavi Simons: Suffered an ACL injury in April, out until next year.Jerdy Schouten: Recovering from an ACL injury.Matthijs de Ligt: Struggling with fitness after a back problem.Frenkie de Jong: Missed most of the season.Denzel Dumfries: Sidelined for four months.Memphis Depay: Sustained a serious hamstring injury.This injury wave means Koeman may have to abandon his favored 4-3-3 formation to field the fittest available squad rather than the most naturally talented one that aligns with traditional Dutch footballing philosophy.Group F Fixtures and Tournament ExpectationsThe KNVB (Royal Dutch Football Association) has set strict performance metrics for the tournament, with a minimum target of reaching the semi-finals. Koeman himself is aiming even higher, targeting the ultimate prize. However, they must first navigate a highly competitive Group F.14 June: v Japan, Dallas20 June: v Sweden, Houston25 June: v Tunisia, Kansas CityThe Oranje will need to hit the ground running against high-caliber opponents like Japan and Sweden to build momentum for the knockout stages.The Shift from Attack to Defensive SolidityHistorically known for producing world-class forwards, the current Dutch generation's strongest asset is undeniably its defense. The team is anchored by Liverpool's Virgil van Dijk, who serves as Koeman's extension on the pitch. At 33 years old, Van Dijk is the undisputed leader, bridging the gap between the dressing room and the coaching staff.Supporting him is the unsung hero, Micky van de Ven. The Tottenham defender brings exceptional pace and energy to the backline. Having fought his way up through Volendam and Wolfsburg, Van de Ven provides the physical resilience Koeman needs to compensate for the missing attacking flair.Can the Dutch Defense Win the Tournament?The Netherlands' success in 2026 will hinge on their ability to adapt. Koeman's personal resilience, balancing the rigors of a World Cup with his wife's ongoing cancer treatment, mirrors the mental grit he demands from his squad. If Van Dijk can marshal a solid defense and the midfield can stabilize despite the absences of De Jong and Simons, the Dutch have the tactical discipline to exceed expectations and make a deep run in the tournament.