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The Lead The United States Centers for Disease Control and Prevention (CDC) has released data showing that deaths from drug overdoses fell by nearly 14 percent in 2025, continuing a third consecutive year of decline. Drug Overdose Deaths in Decline The data released on Wednesday shows that the US saw nearly 70,000 predicted overdose deaths in 2025, down from more than 81,000 in 2024. The downward trend has been welcomed in the US, which has struggled with a devastating overdose crisis fuelled largely by synthetic opioids. The Data Analysis Overdose deaths peaked during the COVID-19 pandemic, with 110,000 recorded in 2022, a surge associated with social isolation and obstacles to accessing treatment services. Experts have attributed the decline to various factors, such as wider availability of the overdose treatment naloxone, commonly sold under the brand Narcan. The Impact Analysis Testing strips that can detect fentanyl are also more common now, and regulatory changes in China have limited access to the chemicals used to manufacture the drug. While overdose deaths declined in most US states in 2025, seven states saw increases. In Arizona, Colorado and New Mexico, overdose deaths increased by 10 percent or more. The Prediction “I’m cautiously optimistic that this represents really a fundamental change in the arc of the overdose crisis,” Brandon Marshall, a Brown University researcher who studies overdose trends, told The Associated Press news service. The administration of President Donald Trump has pointed to the decrease overall as validation of its crackdown on drug trafficking.

The Western Australian Government's Climate Stance Western Australia has been known for its beautiful landscapes, beaches, and roads. However, its government has taken a stance on climate change that is concerning. They believe they shouldn't be expected to act on the climate crisis in the same way as the rest of Australia. Climate Targets and Emissions Documents released under freedom of information laws show that Western Australia's gas exports risk slowing Asia's shift to clean energy. The state's annual pollution increased by 4% last year, and its emissions have grown 17% since 2005. In contrast, other states have reduced their emissions. The Impact of Fossil Fuel Expansion The Western Australian government has continued to back fossil fuel expansions, arguing that gas exports reduce coal burning in Asia. However, experts say that gas is still a fossil fuel and contributes to greenhouse gas emissions. A US study found that liquified natural gas exports can be dirtier than coal when emissions from extraction, piping, processing, and shipping are counted. The Role of the Federal Government The Albanese government has given implicit support to Western Australia's climate position. However, experts say that the federal government should take action to address the issue. A question for the prime minister is whether he intends to do anything about Western Australia's climate targets risk. The Future of Fossil Fuel Projects A big decision lies ahead for the federal government: a verdict on the Browse development, Australia's largest untapped gas basin, is expected before the end of the year. Experts say there is a stronger than usual legal case that it could be blocked on environmental grounds, given the risk to protected species.

The Lead The V&A;'s "Rising Voices" exhibition attempts to condense three decades of art from across Asia, Australia, and the Pacific into just three rooms, creating both an impressive display and significant limitations in telling the full story of the region's diverse artistic traditions. The Exhibition's Cultural Treasures The opening room features an array of remarkable works including bark cloth paintings from Papua New Guinea, Indigenous Australian abstracts, shark sculptures from the Torres Strait, and Tahitian textiles. Indigenous and First Nations artists form the heart of the exhibition, with stunning pieces like Lila Warrimou and Pennyrose Sosa's hypnotic bark cloth paintings where every shape carries specific cultural meanings. Aline Amaru's Tahitian quilt tells the story of her husband's dynastic lineage, representing the rich cultural heritage preserved through art. Art as Historical and Political Resistance Many works in the exhibition carry the heavy burden of colonial history. Elisabet Kauage depicts Melanesian figures being transported in Captain Cook's ship, while Sri Lankan artist Pala Pothupitiye paints over historical colonial maps to expose injustices. Brenda V Fajardo portrays Filipino women enduring under colonial rule. Beyond historical contexts, many artists created work under political oppression—Svay Ken painted quietly through Cambodia's Khmer Rouge regime, Heri Dono produced his grotesque cubistic works under President Suharto's dictatorship, and Maryam Ayeen and Abbas Shahsavar depict contemporary Iranian life pressures. The Exhibition's Design Limitations The presentation of this vibrant art faces significant criticism. The exhibition employs "dull, grey and depressing lighting more akin to a funeral home" that fails to showcase the bright, colorful nature of the works. A single, mournful piano ballad loops loudly throughout the space, creating an unwelcoming atmosphere that discourages prolonged viewing. These design choices undermine the powerful and often beautiful artworks they're meant to highlight. The Challenge of Comprehensive Representation The fundamental issue lies in the exhibition's scope—attempting to represent art from dozens of countries, countless Indigenous populations, and multiple continents in just three rooms. Each segment—Pakistani miniature painting, Indigenous Australian photography, Papua New Guinean textiles—deserves its own comprehensive exhibition. The current format offers merely "a barely cracked window into a vast world" without providing a cohesive narrative thread connecting these diverse artistic traditions. The Future of Global Art Exhibitions The "Rising Voices" exhibition highlights both the richness of Asia-Pacific art and the challenges of representing such diversity within institutional constraints. Future exhibitions of this scale must either commit to comprehensive, in-depth explorations of specific artistic traditions or develop stronger curatorial frameworks that can meaningfully connect diverse works without reducing their cultural significance. The V&A; has presented a glimpse into a vast world of art, but there remains immense opportunity to more fully celebrate the incredible diversity of contemporary art from across this region.

The Legacy of a Scientific Pioneer My husband Peer Bork, who has died unexpectedly aged 62, was a bioinformatician with a remarkable ability to identify new directions in science and carry out world-class research to push them forward. Revolutionizing Microbiome Research During his career, he progressed from the statistical analysis of the sequences of individual protein molecules, via the analysis of the human genome, to the bioinformatics analysis of whole microbial communities. Peer pioneered the computational analysis of the human microbiome, introducing the concept of gut enterotypes – in work that was highlighted in many newspaper articles as well as on the radio and TV. He went on to study microbial ecosystems worldwide and, at the time of his death, was involved in expanding a consortium that he had initiated to systematically document coastal ecosystems in Europe. All these studies required the creation of bioinformatics tools – software and curated datasets – which are now widely used by the scientific community in academia and industry. A Life in Science Peer was born in the former East Berlin, where his father, Joachim, worked in economic statistics, and his mother, Regina, had an administrative job in the construction industry. Owing to his mathematical abilities, he won a place at a high school specialising in mathematics and science, the Heinrich-Hertz-Oberschule. After military service on the border between East and West Germany, he studied biochemistry at the University of Leipzig. He followed this with a PhD in bioinformatics under the supervision of Jens Reich at the Central Institute for Molecular Biology of the Academy of Sciences of the GDR in Berlin. International Scientific Career After the fall of the Berlin Wall in 1989, Peer joined the European Molecular Biology Laboratory (EMBL) in Heidelberg in 1991 as a visiting scientist. He and I met there and married in Canterbury, Kent, in 1994. We had two sons, Udo and Robin, and family life involved many trips between Germany and Britain. EMBL became Peer's scientific home and he rose up the ranks to become interim director general in 2025. He was dedicated to furthering EMBL – an intergovernmental research organisation with six sites, including the European Bioinformatics Institute near Cambridge. He was an outstanding mentor. Awards and Recognition He made science both challenging and fun. Among his awards, which included honorary doctorates and the 2009 Royal Society and Académie des Sciences Microsoft award, he was particularly proud of the Nature award for mentoring in science he received in 2008. Final Scientific Journey He died in Taiwan, where he was due to speak at an international conference on the microbiome. He loved to travel and make friends all over the world. Peer is survived by me, his sons, by a granddaughter and his mother.

The Lead: Preserving Environmental HistoryOver four years in the 1820s, Charles Waterton built a 9ft-high, 3-mile-long wall around the parkland and lake of Walton Hall in Yorkshire, creating what could be the world's first nature reserve. Now, the overlooked achievements of this innovative reserve and the crumbling wall that still surrounds Waterton's former home are being remembered through WallFest, a programme of 60 community events organised by a charity dedicated to protecting the wall and preserving its legacy.The Historic Wall: Engineering Environmental ProtectionThe wall, built between 1820-1824, was designed to be fox- and poacher-proof, enclosing Waterton's estate and creating a sanctuary for wildlife. After completing the wall and banning hunting and shooting, Waterton recorded 5,000 wildfowl on his lake and 123 species of birds, including those widely persecuted at the time, such as herons and kestrels. The boundary allowed hedgehogs and so-called vermin, like weasels, to roam freely through his reserve.Waterton's Environmental Legacy: A Pioneer Ahead of His TimeWaterton, an eccentric, controversial and pioneering environmentalist, implemented innovative conservation practices long before they became mainstream. He built nest boxes, special banks for sand martins and innovative bird hides, and offered local people sixpence for every hedgehog they brought into his reserve. Unlike sportsman-naturalists of the day, Waterton abhorred shooting and got into fistfights with armed poachers, thwarting their attempts to kill birds by placing dummy birds made from metal and wood in the trees.Waterton's environmentalism began after experiencing the natural wonders of the rainforests of Guyana, where he managed his father's sugar plantations. Upon returning to his family home in rapidly industrializing West Yorkshire, he was dismayed at the polluted state of waterways, woodlands stripped of birdlife and workers looking ill.The Conservation Challenge: A Wall in PerilToday, the historic wall has collapsed in places and is in urgent need of repair. Some sections have completely deteriorated, threatening the physical boundary that Waterton created and the historical significance it represents. The Friends of Waterton's Wall charity was created after Covid when local residents realized the wall they walked beside daily might not last another century.Waterton also launched one of the first known environmental legal actions, against a nearby soap works for releasing pollutants that killed trees and damaged his lake. Despite his visionary environmentalism, Waterton is mostly remembered for his eccentricity rather than his groundbreaking conservation efforts.WallFest: Community Action for HeritageThe WallFest events, taking place during May around the village of Walton, West Yorkshire, and in Waterton's former home (now a hotel), will help raise funds to repair the crumbling wall. The festival includes a short film supported by David Attenborough and various community activities designed to raise awareness of both the wall's condition and Waterton's environmental legacy."We're keen to raise the profile of the first nature reserve in the world," said John Smith, the chair of trustees of Friends of Waterton's Wall. "Waterton was a pioneering environmentalist, probably the first in this country. We also want to raise the profile of the wall itself and the need to preserve our heritage for future generations."The Future Outlook: Rediscovering an Environmental PioneerAccording to Barbara Phipps, a local resident and author of a biography of Waterton, his historical portrayal as "an amusing and strange fellow," in the words of Charles Darwin, was partly because he was a Catholic and was discriminated against, being excluded from mainstream careers in politics, law and the military.John Whitaker, a curator at Wakefield council's museums and castles and a trustee of the charity, also attributed the lack of acclaim for Waterton to his Catholicism. "He was a marginalised aristocrat, which is a weird situation to be in. He was never in the establishment. He was massively affectionate and incredibly progressive in many ways but also hugely contradictory."As WallFest aims to raise both funds and awareness, there's hope that Waterton's true legacy as an environmental pioneer will be properly recognized and that the historic wall will be preserved for future generations to appreciate.

Trump's Arrival Signals a Diplomatic ResetOn May 13, 2026, Donald Trump touched down in Beijing for a scheduled two‑day summit with Chinese President Xi Jinping. The meeting follows months of diplomatic overtures by the current U.S. administration, aiming to stabilize a relationship strained by trade wars, technology bans and regional security disputes.Agenda Highlights and Expected Talking PointsTrade imbalances and potential tariff adjustments.Technology transfer restrictions and semiconductor supply chains.Security concerns in the South China Sea and Taiwan Strait.Climate cooperation and joint infrastructure projects under the Belt and Road Initiative.Absence of Immediate Economic FiguresThe summit has not yet released concrete financial commitments or trade figures. Both delegations have emphasized that any agreements will be announced after detailed negotiations, leaving markets to await official statements.Strategic Implications for U.S.–China RelationsThe meeting could reshape the geopolitical landscape by:Providing a channel for de‑escalation of military posturing in the Indo‑Pacific.Potentially reopening dialogue on tariff reductions, which could affect global supply chains.Testing the new U.S. administration’s willingness to engage directly with a former president’s personal diplomacy.Outlook: What May Follow the SummitAnalysts anticipate that any breakthroughs will be incremental, focusing on confidence‑building measures rather than sweeping policy shifts. A successful summit could pave the way for a follow‑up working group on trade and technology, while a stalemate may reinforce the status quo of strategic competition.

The Global Obesity Landscape: Not a Uniform EpidemicA continuing rise in obesity around the world is not inevitable, research suggests, with rates in some countries levelling off or potentially in decline. Researchers say focusing on what has been described as a global epidemic of obesity hides large variations in trends across different countries, sexes and age groups.Majid Ezzati, a professor of global environmental health at Imperial College London and author of the study, said: "I think the thing that's really important is this diversity exists even across countries that have really similar economic, environmental, technological features. So countries may look the same on the surface of it but obesity looks different."Comprehensive Analysis Reveals Complex PatternsWriting in the journal Nature, the international team, which involved a network of almost 2,000 researchers, described how for each country they calculated the change in the prevalence of obesity each year between 1980 and 2024. They drew on data from 4,050 population-based studies involving 232 million participants aged five years and above.They found that the prevalence of obesity increased in almost all countries over the 45-year period. However, in most high-income countries, a rapid rise in the prevalence of obesity has been replaced by a slower increase, a plateau, or a potential decline.Regional Variations in Obesity PrevalenceThe rate of growth in obesity is slowing in adults in the US and UK, reaching a prevalence of 40-43% and 27-30% respectively in 2024. Obesity is increasing steadily in Finland, has plateaued in Germany and may have started to decline in France, where 24-25%, 20-23% and 11-12% of adults respectively were thought to have the condition in 2024.Slowdowns were often seen in children and adolescents before adults. For the former group, the slowdown started as early as 1990 in Denmark and rates stabilised in most high-income countries by the mid-2000s. Obesity has plateaued in boys and girls in the UK, US, Germany and Japan at prevalences of 10-12%, 20-23%, 7-12% and 3-7% respectively.Meanwhile, obesity among young people and adults in many low-income and middle-income countries continues to rise and in some cases this is accelerating.Understanding the Drivers Behind Divergent TrendsThe team say it is important now to unpick what is behind the trends in different countries. The situation is complex: while there may be shared reasons for obesity, such easy access to unhealthy foods or a decrease in physical activity, the team say country-specific factors rooted in social, economic and policy considerations could also be important, from perceptions around body image to the presence or absence of interventions such as healthy school meals.Naveed Sattar, a professor of metabolic medicine at the University of Glasgow, who was not involved in the work, said the study highlighted how obesity trends were diverging sharply across countries. "English-speaking nations are doing particularly poorly, with the UK now among the countries with the highest obesity levels worldwide," he said.Sattar said it was encouraging that some countries appeared to have reached a plateau in obesity rates. "Understanding what has worked in those settings is crucial as it could help shape more effective public health strategies for the UK," he said, although he noted there could be country-specific aspects or customs at play.Future Outlook and Potential InterventionsHe said the rapid rise in obesity across many developing countries was especially concerning, not least as it could result in increases in diabetes and cardiovascular conditions.He added: "Looking ahead, it will be important to see how wider use of effective weight-loss medicines affects obesity trends, particularly in the UK and the United States. Recent signs of stabilisation in the USA suggest there may be room for cautious optimism. Combining evidence-based medicines with strong public health measures could begin to shift obesity rates in the right direction."

Smithsonian's Monumental Celebration of America's 250 Years To paraphrase the musical Rent, 131,487,300 minutes – how do you measure, measure 250 years? Especially in a country navigating an election year fraught with divisions and disagreements over basic facts? That is the challenge facing the Smithsonian National Museum of American History in Washington DC as it marks the semiquincentennial of US independence. The museum's answer is with 250 objects that tell the American story, ranging from a revolutionary war-era gunboat to gloves worn by a "Miracle on Ice" hockey player, from Thomas Jefferson's desk to a Donald Trump fan's "Make America great again" hat. A Museum-Wide Journey Through American History Opening on 14 May, "In Pursuit of Life, Liberty & Happiness" will display 250 objects encompassing 250,000 sq ft across all three floors of the museum. They range from old to new, from big to small and from sublime to mundane. Seventy-six of them – many rarely or never seen by the public – will be concentrated in cases lining the entry halls, while the remainder will be embedded throughout the museum's existing galleries, connected by a "ribbon" design to guide visitors on a historical treasure hunt. Each is paired with an action verb to underscore the view of democracy as a "highly participatory sport." Among the star attractions is the Philadelphia, a 53ft, flat-bottomed wooden gunboat constructed in the chaotic, sweltering summer of 1776. On a recent preview tour, visitors stepped into a climate-controlled enclosure at the museum where the air was thick with the scent of 100% acetone. Behind viewing windows that allow the public to see the work in progress, two conservators clad in headlamps and respirators were meticulously wielding soft and stiff bristle brushes, dental picks and wooden dowel rods to strip away decades of accumulated lacquer from a rusted iron cannon and its surrounding timber. By the Numbers: The Scale of the Exhibition The exhibition features 250 objects spread across 250,000 square feet of museum space. Seventy-six of these objects – many rarely or never seen by the public – will be concentrated in cases lining the entry halls. The Philadelphia gunboat itself weighs 16,000 pounds and was constructed in 1776. The wreck languished underwater for 159 years before being salvaged in 1935, fully intact with its armament and hundreds of artifacts scattered across its deck. When raised, the boat revealed about 600 to 800 items, including cannons, carriages, wheels, a stew pot, a melting pot for pitch, shoe leather, buttons from regimental coats, and even a leather button that was probably from someone's breeches. Reframing America's Complex Narrative "How do you structure a commemoration, celebration and time for reflection?" asks Anthea Hartig, the museum's director. "What we landed on were those moments where individuals or communities had fought for recognition and advocated for their own sense of identity and self in their role in creating and becoming a part of the United States. But we also wanted to do the playful." Hartig describes the US as "amazing, beautiful, complicated", and cites the African American writer James Baldwin's celebrated observation: "American history is longer, larger, more various, more beautiful, and more terrible than anything anyone has ever said about it." The exhibition captures both the monumental and the intimate aspects of American history. Alongside iconic items like Thomas Jefferson's portable desk on which he drafted the Declaration of Independence, the Star-Spangled Banner that inspired the national anthem, and George Washington's military uniform, are personal artifacts like a faux-pearl necklace worn by Abigail Adams in the mid-18th century. The Future of Historical Commemoration Hartig adds: "We believe that this anniversary is so important not only to the nation but the world, and that our past 250 years are filled with so much history that it takes an entire museum to do it justice." The exhibition also incorporates modern technology to enhance the visitor experience, including a virtual reality experience that transports visitors back to the Philadelphia's construction 250 years ago. As the museum continues to preserve and interpret America's complex past, the exhibition represents a new approach to historical commemoration – one that embraces the full spectrum of American experiences, from the revolutionary to the contemporary, and from the sublime to the mundane.

The Daring Debut of Angel's Bone English National Opera takes a bold leap with Du Yun's Angel's Bone, a Pulitzer Prize-winning opera that tackles human trafficking head-on. This inaugural production at ENO's northern base, a collaboration with Factory International and the BBC Philharmonic Orchestra, features Kip Williams' innovative direction. The Unsettling Allegory The opera tells the story of two angels who fall into the clutches of a dysfunctional couple, leading to a descent into physical and sexual abuse. Du Yun's score is a genre-bending mix of contemporary classical and nightclub electronica, performed by a tireless ensemble of 10. The Data Analysis: A Complex Soundtrack The music operates at extremes, with key roles assigned to tuba and lute. The instrumental palette offers textural beauty, but also joyously kicks ass. The score is expertly conducted by Baldur Brönnimann. The Impact Analysis: A Powerful Statement The production is a powerful statement against human trafficking, with a clear and admirably clear storyline. However, the endlessly rotating walls can be problematic, forming an impenetrable barrier that obscures the screens at times. The Prediction: A Must-See Performance Despite some technical issues, the production is a must-see, with standout performances from Allison Cook as Mrs X E and Rodney Earl Clarke as her browbeaten husband. The production transfers to London later in the year, rejigged for the Coliseum's proscenium stage, and is one to catch.