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The Challenges of FDA Approval Surviving the long road to FDA approval isn’t just about building great technology — it’s about keeping your team motivated, finding the right investors, and learning how to operate when timelines are uncertain. Lessons from BioticsAI This week on Build Mode, Isabelle Johannessen sits down with Robhy Bustami, co-founder and CEO of BioticsAI, a Startup Battlefield-winning company building an AI copilot for ultrasound to help detect fetal abnormalities. From a $100,000 prototype to FDA clearance, Bustami shares what it actually takes to build in one of the most regulated industries in the world. Building a Medtech Startup In this episode, they break down what it really looks like to build a medtech startup, including where you can’t “move fast and break things” and that every milestone takes time, coordination, and trust. Key Takeaways Team motivation is crucial during the long FDA approval process Finding the right investors is essential for medtech startups Adaptability is key when dealing with uncertain timelines Future Outlook As the medtech industry continues to evolve, startups like BioticsAI will play a critical role in shaping the future of healthcare technology. With the right approach and mindset, these companies can overcome the challenges of FDA approval and make a lasting impact.

The Emotional Departure of a Tottenham CaptainBethany England, the captain of Tottenham Hotspur Women, has confirmed her departure from the club at the end of the current season in an emotional video message shared with fans. The 31-year-old striker, who has been instrumental to the team's success during her three and a half years at the club, expressed her deep appreciation for the support she received during her time at Tottenham.Strategic Squad Evolution at TottenhamThe club's decision not to renew England's contract is part of a broader strategy to evolve the squad with younger players. Multiple sources have emphasized that Tottenham is expected to be aggressive and highly ambitious in the upcoming transfer market. This move comes alongside several other confirmed summer exits, including Amy James-Turner, Luana Bühler, Charlotte Grant, Josefine Rybrink, and Kit Graham, indicating a significant transformation of the squad.England's Remarkable Statistical LegacyDuring her time in the Women's Super League, England has established herself as one of the competition's most prolific scorers. She is the WSL's second-highest goalscorer in the division's 15-year history, with 89 goals—eight behind record holder Vivianne Miedema. In March 2026, she became only the seventh player to reach 200 WSL appearances, a testament to her consistency and quality at the highest level of women's football in England.Impact on Tottenham and Women's FootballEngland's departure represents a significant loss for Tottenham, both on and off the pitch. During her tenure, she helped the team reach the 2024 Women's FA Cup final and was crucial in steering the team clear of relegation during her first six months after arriving from Chelsea. Her leadership has been described as having "shaped a defining era" in Tottenham women's football history, driving up standards, professionalism, and desire within the squad.Future Outlook for England and TottenhamAs a free agent with an impressive track record, England is likely to be highly sought after by other clubs. Her experience, goal-scoring prowess, and leadership qualities make her an attractive addition to any team. Meanwhile, Tottenham appears set on a summer recruitment drive to rebuild their squad with younger talent, signaling a new direction for the club as they aim to compete at the highest level of women's football in the coming seasons.

The Interception of the Gaza Aid Flotilla Israel has intercepted 22 out of the 58 aid ships traveling through international waters and bound for the besieged Gaza Strip. The ships were part of a second Global Sumud Flotilla aimed at breaking the Israeli blockade by carrying humanitarian aid to Palestinians in Gaza. International Reactions The international community has reacted strongly to Israel's interception of the aid flotilla. Italy, Spain, and Turkey have all condemned the action, with Turkey's Foreign Ministry calling it 'an act of piracy'. Italy's Response Italy has called for the immediate release of Italian nationals on board the flotilla, condemning the seizure of the vessels and urging Israel to respect international law. Spain's Condemnation Spain's Foreign Ministry has 'energetically condemned' Israel's seizure of the flotilla, summoning Israel's charge d'affaires to convey its protest over the detention of the vessels. Turkey's Strong Words Turkey's Foreign Ministry has condemned Israel's seizure of the boats in the flotilla as 'an act of piracy', stating that Israel has violated humanitarian principles and international law. Hamas' Response The Palestinian group Hamas has condemned the interception, accusing Israel of committing a crime without accountability and calling for the release of those detained. Israel's Justification Israel's Foreign Ministry has called the flotilla organizers 'professional provocateurs', stating that its forces acted lawfully to prevent the breach of a lawful blockade.

The Rise of Fan Theories The HBO series The Pitt has become a sensation, captivating audiences with its intense medical drama and complex characters. As fans eagerly await the next season, they have begun to speculate about potential plot twists and relationships between characters. Romantic Relationships and Speculations One of the most popular fan theories revolves around the relationship between Dr. Michael 'Robby' Robinavitch (played by Noah Wyle) and Dr. Dennis 'Huckleberry' Whitaker (played by Gerran Howell). Fans have speculated that the two characters may be romantically involved, with some even creating fan art featuring the pair. The AI Conundrum Another theory suggests that the use of AI-driven medical tools could lead to a patient's death. This speculation centers around Dr. Baran Al-Hashimi (played by Sepideh Moafi), who has been promoting the use of AI in medical diagnosis. However, with an accuracy rate of only 98%, some fans believe that this could lead to a tragic mistake. The Mysterious Dr. Abbot Some fans have questioned the existence of Dr. Jack Abbot (played by Shawn Hatosy), suggesting that he may be a figment of Dr. Robby's imagination. However, with Dr. Abbot interacting with other characters, this theory seems unlikely. The Adoption Theory A poignant theory suggests that Dr. Robby may adopt an abandoned baby, known as 'Baby Jane Doe', who has been undergoing pediatric tests in the hospital. However, Noah Wyle has debunked this theory, stating that Dr. Robby will not be filling out adoption papers. Tragedy Strikes Some fans believe that tragedy may strike one of Dr. Robby's colleagues, specifically Dr. Trinity Santos (played by Isa Briones). With her struggles in her second year of residency and her rocky relationship with Dr. Yolanda Garcia, some speculate that she may make a critical mistake. The Unsung Hero Finally, some fans believe that Myrna, a character in a wheelchair, may be the real star of the show. While her role may seem minor, fans have praised her character for adding depth to the story.

The Health Crisis of a Jailed Opposition LeaderJailed Tunisian opposition leader Rached Ghannouchi has been urgently transferred to a hospital after experiencing a sharp deterioration in his health, according to his party Ennahdha. The 84-year-old former speaker of parliament and head of the Ennahdha party has been imprisoned since April 2023 in what his supporters and international rights groups describe as a politically motivated campaign to crush dissent.In a statement on Thursday, Ennahdha's media and communications office confirmed that prison authorities were forced to transfer Ghannouchi to hospital for treatment and continuous medical observation over the coming days. The party did not provide specific details regarding his current medical condition, but noted that he suffers from chronic illnesses that require constant family care and attention due to his advanced age.Multiple Prison Sentences and Arbitrary DetentionGhannouchi's hospitalization comes amid multiple prison sentences totaling over 25 years. He was initially arrested in April 2023 on charges of incitement and sentenced to one year in prison. In February 2024, a financial corruption court sentenced him to three years over accusations that his party received foreign contributions – a charge Ennahdha vehemently denied. In February 2025, he was handed a 22-year prison sentence on charges including plotting against state security."In light of this dangerous development, the movement renews its demand for the immediate release of Mr Rached Ghannouchi, considering him arbitrarily detained," the Ennahdha statement read. The party pointed to a 2024 decision by a United Nations committee of experts, which concluded that Ghannouchi is being prosecuted for his freedom of opinion and expression, and that the charges against him lack any legal or factual basis.Widening Crackdown on Political OppositionGhannouchi's situation is part of a broader crackdown on political opposition orchestrated by President Kais Saied. Elected in 2019, Saied – a former law professor – suspended the Tunisian parliament in 2021 and subsequently dissolved the legislature to rule by decree. He later pushed through a controversial referendum on a new constitution that vastly expanded presidential powers, which the opposition has described as a coup.Since consolidating power, Saied's government has targeted numerous opposition figures, journalists, lawyers, and activists. In November 2025, Jawhar Ben Mbarek, cofounder of the National Salvation Front, was hospitalised due to severe dehydration during a hunger strike protesting his detention. Shortly after, prominent opposition figure Ayachi Hammami was arrested in December 2025 to enforce a five-year prison sentence following a mass trial of opposition members.International Condemnation and Human Rights ConcernsHuman rights organisations, including Human Rights Watch (HRW) and Amnesty International, have consistently condemned the arrests. In a 2025 report, HRW stated that Tunisia's government had turned arbitrary detention into a cornerstone of repressive policy."Saied's government has returned the country to an era of political prisoners, robbing Tunisians of hard-won civil liberties," said Bassam Khawaja, HRW's deputy Middle East and North Africa director. Despite international criticism, Saied has denied accusations of authoritarianism, maintaining that his actions are necessary to fight corruption, rescue the country from political chaos, and hold those he labels as "terrorists" accountable.Future Outlook for Tunisia's Political LandscapeGhannouchi's hospitalization has intensified international scrutiny on Tunisia's human rights situation. With the health of the highest-profile opposition figure deteriorating, pressure is mounting on President Saied's government to address concerns about arbitrary detention and political prisoners. The Ennahdha party has emphasized that "the natural place for Mr Rached Ghannouchi is to be free in his home among his family," citing his constitutional right to necessary healthcare and international treaties ratified by Tunisia.As Tunisia approaches potential political transitions, the treatment of opposition figures like Ghannouchi will likely remain a critical point of contention both domestically and internationally. The international community continues to monitor the situation closely, with human rights organizations likely to further document and report on developments in the coming weeks and months.

Union Calls for Dispute Procedure Over FT’s Four‑Day Office PlanFinancial Times journalists, represented by the National Union of Journalists (NUJ), have unanimously voted to trigger the company’s formal dispute process. The union argues that management has "not made a compelling case" for increasing office attendance from the existing three days to four days a week by the end of 2026.Dispute invoked after a “fiery meeting” with managing editor Tobias Buck.NUJ officers were notified of the dispute this week.Potential escalation to a strike ballot remains on the table.Details of the Proposed Four‑Day Office PolicyThe FT’s proposal targets the London editorial team based at Bracken House, comprising roughly 500‑600 staff members. About two‑thirds of these employees are union members.Current arrangement: three days in the office, two days remote.Proposed change: mandatory presence for four days each week.Excludes other FT divisions (commercial, IT, events, HR, FT Specialist) and overseas bureaus, which would retain flexible hybrid schedules.Key concerns raised: discrimination against parents (especially mothers), financial strain, and breach of prior hiring commitments based on a three‑day model.Financial Context: FT’s Revenue Growth vs. Profit PressuresDespite the labour dispute, the FT reported solid top‑line performance:Global revenues rose 6% to £540 million in 2024.Global operating profit jumped 41% year‑on‑year to £42.2 million.UK‑specific revenue grew 2% to £454.6 million, but operating profit fell 19% to £7.3 million, attributed to inflation and the addition of 30 new employees.Paying audience expanded from 2.57 million (end‑2023) to 2.83 million (end‑2024); total FT readers reached 1.48 million, with 1.35 million digital subscribers.The FT is owned by Japanese media group Nikkei, which acquired it in 2015 for £844 million.Implications for UK Journalism and Hybrid Work TrendsThe dispute highlights a broader tension in the media sector between cost‑control, productivity expectations, and evolving work‑life balance norms.Potential precedent: If the FT enforces a stricter office mandate, other legacy publishers may follow, reshaping hybrid policies across the industry.Risk of talent attrition, especially among parents and younger journalists who value flexibility.Union pressure could force a renegotiation of hybrid contracts, influencing future collective bargaining in UK newsrooms.What May Come Next: Potential Strikes and Industry Ripple EffectsBoth sides remain in talks, but several scenarios are plausible:Negotiated compromise: A reduced office requirement (e.g., three‑and‑a‑half days) or opt‑out provisions for parents.Industrial action: A NUJ‑led strike could disrupt FT publishing schedules, prompting advertisers to reconsider placements.Sector‑wide impact: Other media organisations may pre‑emptively adjust hybrid policies to avoid similar disputes, accelerating a shift toward more flexible work models.Stakeholders will watch closely as the FT balances financial performance with staff morale and the evolving expectations of a post‑pandemic newsroom.

The Tactical Chess Match at the EmiratesNorth London witnessed a masterclass in defensive pragmatism mixed with attacking flair as Arsenal and Atlético Madrid settled for a 1-1 draw in the first leg of their Champions League semifinal. The match, played on April 30, 2026, was characterized by a high-intensity tactical stalemate, where Mikel Arteta attempted to unlock a stubborn Diego Simeone defense with intricate passing patterns, while Atlético relied on rapid transitions and counter-pressing to negate Arsenal's dominance.Defensive Resilience Meets Attacking IntentArsenal started the match with overwhelming possession, registering over 65% of the ball, but struggled to convert territory into clear-cut chances against a compact backline. The breakthrough came when Leandro Trossard found space in the box to slot home a cross from Bukayo Saka. However, Atlético's resilience was tested but not broken. Their equalizer arrived late in the second half through a well-worked set-piece routine, with Alexis Mac Allister converting from the penalty spot after a VAR review.Key Turning Points0-45': Arsenal dominated possession but struggled to break down the Atletico Madrid low block.52': Leandro Trossard breaks the deadlock with a clinical finish.78': Alexis Mac Allister equalizes from the penalty spot after a VAR review.90+3': Both teams had late chances to win it, but the score remained 1-1.Implications for the Title RaceThis draw is a significant psychological boost for Atlético Madrid, who travel to the Emirates with a valuable away goal. For Arsenal, the result prevents a potential psychological blow but highlights a recurring issue: the inability to kill off games against top-tier defensive units. The draw keeps the Premier League title race tight, as Arsenal's lead over their rivals has been reduced by a point.Outlook for the Second LegThe second leg at the Metropolitano promises to be a high-stakes thriller. With the tie evenly balanced, both managers are likely to switch from a cautious approach to a more aggressive one. Arsenal will need to find a way to bypass Atlético's midfield press, while Simeone's side will look to exploit the spaces left by Arsenal's full-backs pushing high up the pitch. The winner of this tie is expected to face either Real Madrid or Bayern Munich in the final.

Jesse Southwell’s Late Field Goal Secures NSW VictoryIn front of 20,000 fans at McDonald Jones Stadium, halfback Jesse Southwell slotted a decisive field goal with seven minutes remaining, sealing a 11‑6 win for the NSW Blues over the Queensland Maroons. Southwell, who moved from Newcastle to Brisbane earlier this season, described the contest as “the fastest and definitely the toughest” she’s ever played.Scoreline, Attendance and Key StatsFinal score: NSW Blues 11, Queensland Maroons 6Attendance: 20,000 spectatorsField goals: Southwell (NSW) – 1; Lauren Brown (QLD) – 1 (missed)Top tacklers: Keilee Joseph (QLD) – 32 tackles by half‑timeDebutants: Millie Elliott (NSW), Phoenix‑Raine Hippi (QLD), Otesa Pule (QLD)What the Win Means for Women’s Rugby LeagueThe narrow victory underscores the increasing competitiveness of the women’s game. After dominating the first two matches of last season (58‑18 aggregate), the Maroons were forced into a hard‑fought loss, signalling that the talent gap is closing. Coaching changes – with Nathan Cross taking the reins for Queensland – and the emergence of new stars like Southwell and Elliott suggest a deeper talent pool and heightened media interest.Looking Ahead to Games Two and Three in QueenslandQueensland will host the next two fixtures, turning the series into a true home‑and‑away showdown. The Blues will aim to protect their lead, while the Maroons will look to leverage home‑field advantage and the momentum of their debutants. If the current trend continues, the series could be decided by a single field goal or a late defensive stand, echoing the drama of this opening match.

The Comeback Story: Coleman's French RenaissanceThere are few Bordeaux Bègles players better qualified to explain how it feels to be at the center of European rugby's newest force quite like Adam Coleman. Three years ago, their paths collided in almost perfect timing, with Bordeaux mid-table and Coleman unceremoniously dropped into rugby purgatory after London Irish's collapse. His move to France has proven to be an inspired decision for both parties, with Coleman playing a pivotal role in UBB's rise to the top of club rugby, culminating in their Champions Cup triumph over Northampton last year.From Career Crisis to Champions Cup GloryColeman's career looked to be over when London Irish went out of business in the summer of 2023 before his move to France with Bordeaux. As a dual-international with both the Wallabies and Tonga, as well as experiencing rugby in almost all corners of the sport's geographical footprint, Coleman is used to the unconventional. Being one of the few non-French speakers in the Bordeaux squad hardly feels too challenging for the 34-year-old, who has taken this challenge in stride to give his career fresh impetus.The Financial and Professional Impact of Overseas RugbyWhen London Irish went down, Coleman genuinely didn't know what would happen next for his career. "But to come here, to meet the people and live in Bordeaux: it's an incredible place," he says. "You get this incredible lifestyle and the opportunity to play with so many great French internationals. There's all the benefits of playing overseas." This move represents more than just a career extension—it showcases how financial instability in one league can lead to unexpected opportunities in another, with clubs like Bordeaux benefiting from experienced international players seeking new challenges.Transforming French Rugby's European AmbitionsThis is no end-of-career French sojourn. There is history aplenty to be made in Bordeaux, with the reigning champions now just two wins away from joining the elite list of clubs who have gone back-to-back in European rugby's premiere competition. Coleman's arrival at Bordeaux in 2023 coincided with Yannick Bru joining as head coach, and while a maiden Top 14 title remains elusive, UBB's success in European rugby suggests more silverware is not too far away. "I can't comment on the last coach because I wasn't here but maybe it was a fresh start that UBB needed," Coleman explains. "It's really showed in the way we're playing and the professionalism of the team and really taking that step forward from where we were when I joined."Path to Back-to-Back Glory: Bath as the First HurdleBath are the first obstacle in Bordeaux's way this Sunday as they seek to defend their Champions Cup title. It promises to be an intriguing affair of contrasting styles. "They like to control the game, put a lot of structure into the game and we like to play a brand of more elusive rugby," Coleman says. "It'll be a good game of rugby." With players like Finn Russell in Bath's ranks and Louis Bielle-Biarrey in Bordeaux's—who Coleman describes as a "once in a generation player"—the quality on display will be exceptional. Coleman turns 35 later this year but there is no sign of him slowing down, with the French lifestyle and the journey Bordeaux are on having clearly gotten under his skin.