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The Middle East remains embroiled in a cycle of violence, with Iranian barrages targeting Israel, Gulf Arab states, and northern Iraq on Tuesday. This escalation comes a day after US President Donald Trump claimed that the US was in 'very good' talks with Iran to end the war in the region soon.Despite Trump's optimistic remarks, multiple official sources in Tehran have denied any talks are underway. Iranian parliament speaker Mohammad Bagher Ghalibaf stated, 'No negotiations have been held with the US … fake news is used to manipulate the financial and oil markets.' The Iranian government remains wary of US offers of negotiation, citing past experiences where talks were followed by attacks, such as the surprise attack that killed the supreme leader Ali Khamenei and dozens of senior officials.Potential intermediaries, including Pakistan, Oman, Egypt, and others, have confirmed tentative efforts to establish channels of communication between Washington and Tehran. Iranian Foreign Minister Abbas Araghchi has been engaging in discussions with his counterparts in several countries, including Azerbaijan, Egypt, Oman, Pakistan, Russia, South Korea, Turkey, and Turkmenistan.The diplomatic activity follows a significant escalation of threats between the US and Iran over the weekend, with both sides trading warnings of potential strikes. On Monday, Trump delayed a deadline for Iran to open the Strait of Hormuz for shipping or face targeted airstrikes on its power stations. This brief reprieve drove down oil prices and boosted stocks, with the deadline now set to expire on Friday.Benjamin Netanyahu has stated that Israel will continue to strike Iran and Lebanon, targeting Hezbollah, the Iran-backed Islamist militant movement. The Israeli prime minister warned, 'There's more to come.'The conflict has already had significant economic impacts, with oil prices rising to $104 (£77) a barrel, up more than 40% since Israel and the US started the war on 28 February. Analysts warn of durable and deep disruption to the supply of oil and gas from the region, even if hostilities end rapidly, with severe economic consequences worldwide.

An Iranian missile has struck central Tel Aviv, causing widespread damage to buildings and vehicles, and injuring at least six people. The attack has led to a significant escalation of tensions in the region, with Israeli Prime Minister Benjamin Netanyahu vowing to continue striking Tehran and Lebanon.“There’s more to come,” Netanyahu said in remarks that appeared to corroborate those of three Israeli officials who told Reuters they thought it was improbable that Iran would accept US demands in any new round of negotiations. This development has dimmed hopes of de-escalation after US President Donald Trump played up the chances of a deal to end the conflict.In a statement released on Tuesday, Iran’s Islamic Revolutionary Guard Corps said it would launch heavy missile and drone attacks at Israeli troops in northern Israel and the area near Gaza “without restraint” unless Israel ceased attacks in Lebanon and Palestine. The threat has raised concerns about the potential for further escalation in the region.Police said an Iranian munition carrying a substantial explosive payload struck the central city, causing widespread damage to buildings and vehicles. At least six people were lightly injured. Several buildings were damaged across Tel Aviv, with emergency services reporting casualties at one of the impact sites. One building and the adjacent road were heavily affected, with cars set ablaze.Israel’s health ministry reports 4,829 injured people have been brought to hospitals since the onset of the war. Of those people, 111 remain in hospital and 12 are in a serious condition. The strikes were the latest in a cycle of retaliation after Israeli operations announced on Monday.About 40 minutes after Trump said he would delay action against Iran’s power infrastructure, Israel said on X that it had “just begun another wave of strikes targeting infrastructure of the Iranian terror regime across Tehran”. The Israel Defense Forces said energy facilities would be spared, suggesting that Israel may be aligning with Washington in suspending attacks on Iranian power plants and related sites.The US-based Human Rights Activists’ News Agency said in the previous 24 hours it had recorded at least 206 attacks across 15 provinces in Iran, resulting in at least four casualties (killed and injured, both civilian and military). At least six people were killed in strikes on homes in the city of Tabriz, according to Iran’s Fars news agency.Since US-Israeli bombs started falling on Iran, estimates of total deaths (military and civilian) in the country have exceeded 1,500, with some rights groups reporting figures as high as 3,230 as of 21 March. The escalation has also spilled beyond Israel, with Iranian strikes extending into Gulf states.

The UK government has rejected a call from the Offshore Energies UK trade body to boost North Sea oil and gas production, despite warnings that the UK will become increasingly reliant on imports at a time of rising global instability.The industry group has urged the government to take action to slow the decline of the North Sea as a provider of energy, citing concerns that consumers will be left more exposed to global volatility and higher emissions if domestic production is not increased.The warning comes as the war in the Middle East has triggered the biggest oil and gas supply shock in the history of the market, causing UK gas prices to more than double in under a month.A government spokesperson said that issuing new licences to explore new fields cannot guarantee energy security and will not reduce bills, adding that the only way to truly protect against price spikes is to get off the rollercoaster of fossil fuel markets.The decline of the North Sea oil and gas basin means that the UK's reliance on gas imports is likely to increase sharply from about 14% last year to more than a quarter of its gas supply by 2030, and almost half by 2035.David Whitehouse, the chief executive of Offshore Energies UK, argued that energy security means backing homegrown oil and gas alongside renewables, and that a stable new tax regime for the industry is essential to reduce reliance on volatile imports and protect skilled jobs.

The United Nations has recorded 143 deaths in an air strike on a drug rehabilitation centre in Kabul, significantly lower than the figure offered by Afghanistan's Taliban government.The attack on Kabul's Omar Addiction Treatment Hospital on Monday night has sharpened a bitter dispute between Pakistan and Afghanistan, with the Taliban putting the casualties at more than 400 people killed and about 265 wounded.The UN Assistance Mission in Afghanistan provided its figure to the Reuters news agency on Wednesday. The gap between the two counts underscores the difficulty of verifying casualty figures in the conflict as competing claims frequently come from Kabul and Islamabad.Afghanistan's Taliban administration has blamed Pakistan for the attack on the drug rehabilitation centre, a 2,000-bed facility, and Pakistan has denied carrying out the strike. Hamdullah Fitrat, a deputy spokesman for the Taliban administration, said the strike hit the hospital, destroying large sections of the building and triggering fires that rescue teams worked through the night to contain.Afghan government spokesperson Zabihullah Mujahid accused Pakistan of deliberately hitting civilian infrastructure and called the assault a “crime against humanity”. Mujahid said those killed and wounded were patients undergoing addiction treatment at the time of the strike.Pakistan's information minister, Attaullah Tarar, denied the allegation, insisting his country “only targeted terrorist infrastructure and military locations”. The strike is the latest in a widening confrontation between the two neighbours, who have engaged in repeated cross-border clashes.At the heart of the dispute is a long-running Pakistani accusation that the Taliban government shelters the Pakistan Taliban, known as Tehrik-i-Taliban Pakistan, as well as outlawed Baloch separatist groups responsible for attacks on Pakistani soil. Kabul has consistently denied providing sanctuary to the groups.

Nigerian President Bola Tinubu was welcomed by UK's King Charles III at Windsor Castle on Wednesday, marking the first state visit by the leader of Africa's most populous nation in nearly four decades.The visit, which concludes on Thursday, highlights the deep cultural and commercial links between the UK and Nigeria, with trade between the two countries currently at a record high.During the visit, Tinubu and his wife were greeted with artillery salutes and shown items from the UK's colonial rule of Nigeria, which ended in 1960. A lavish state banquet was also held in their honor.The Nigerian presidency described the visit as a 'renewed chapter' in UK-Nigeria relations, reflecting a shared commitment to 'advancing trade and strengthening diplomatic ties'.Tinubu is also expected to meet with British Prime Minister Keir Starmer and members of the Nigerian community in the UK. Notably, the visit went ahead despite a deadly bombing in northeastern Nigeria's Borno State on Monday, which killed 23 people and injured over 100.

In the final moments of January 29, 2024, five-year-old Hind Rajab’s desperate pleas for help were cut short as she remained trapped in a car surrounded by the bodies of six relatives. Despite obtaining clearance from the Israeli military, a Red Crescent ambulance dispatched to rescue the child was struck by tank fire, killing two paramedics and leaving the vehicle abandoned for over a week.Two years after the tragedy, the global campaign group Avaaz has released a report alleging that this incident was a deliberate 'double-tap' strike. This tactic, often used in warfare, involves a first attack followed by a second strike targeting civilians or emergency responders attempting to assist victims of the initial assault.The Avaaz analysis, shared exclusively with Al Jazeera, documents over 40 alleged human rights violations and argues that the attack contravenes international combat law, specifically the Geneva Conventions and the Rome Statute. The report suggests that the Israeli military possessed full situational awareness of the rescue mission but deliberately targeted the ambulance.Forensic evidence contradicts the Israeli military's initial claims that the family car was destroyed during an exchange of fire. Analysis by Forensic Architecture at Goldsmiths, University of London, found no evidence of combatants in the vicinity, only the presence of Israeli Merkava tanks. The report highlights that the ambulance was fired upon with 120mm tank rounds without warning, a finding supported by the Hind Rajab Foundation, which has identified 24 potential perpetrators.'I am absolutely convinced that this is another case of double tap,' said Sarah Andrew, legal director of Avaaz. 'The kind of weaponry used on the ambulance, the timing, and the fact that no warning was given – it immediately triggered a question in my mind.'The Avaaz brief urges the International Criminal Court (ICC) to investigate the matter. The group notes that more than 1,500 healthcare workers have been killed during the ongoing conflict in Gaza, raising serious concerns about the safety of medical personnel in the region.

Israeli settlers carried out coordinated attacks on multiple towns and villages in the occupied West Bank for the second consecutive night, resulting in at least nine Palestinian injuries. The violence took place during the Eid al-Fitr holiday, marking the end of Ramadan.In one incident, a 45-year-old man was shot in the foot during a confrontation with Israeli settlers in Deir al-Hatab, east of Nablus. The Palestine Red Crescent Society (PRCS) reported that a 47-year-old Palestinian man was attacked by settlers in Jabal al-Arma in Beita, while others were beaten.The attacks were widespread, with homes and cars set ablaze and property vandalized across the occupied West Bank. Simultaneous assaults occurred in at least six communities, including villages near Jenin and Nablus.The violence followed a funeral for 18-year-old Yehuda Sherman, an Israeli settler killed in a collision with a Palestinian vehicle. Israeli police are investigating claims that the collision was deliberate.The Israeli government's expansion of illegal settlements in the occupied West Bank has been met with international criticism. The United Nations Office for the Coordination of Humanitarian Affairs reported that 25 Palestinians have been killed by Israeli settlers and soldiers so far this year.Amnesty International condemned the expansion of illegal settlements and state-backed settler violence, calling it a "direct indictment of the international community's catastrophic failure" to take action. The International Court of Justice ruled in 2024 that Israel's continued presence in the occupied Palestinian territory is unlawful and should end "as rapidly as possible".

At least two people have been killed in a tragic incident involving an Air Canada Express flight that struck a ground vehicle while landing at New York's LaGuardia Airport. The accident occurred on Sunday night, and the airport has been closed since then, with flights diverted to other airports. The aircraft, operated by Jazz Aviation, a regional partner of Air Canada, collided with a firefighting truck on Runway 4 at approximately 11:40 pm on Sunday (03:40 GMT on Monday). The vehicle was driving to respond to a separate incident. According to the Port Authority, 32 of the 41 injured individuals had been released by Monday, while nine remained hospitalized with serious injuries. The passengers and crew members on board Flight AC8646, which departed from Montreal, included 76 people, four of whom were crew members. The CRJ-900 aircraft struck the vehicle at a relatively low speed of 39 kilometers per hour (24 miles per hour). Emergency response protocols were immediately activated, and the US Federal Aviation Administration (FAA) issued a ground stop for all departures to LaGuardia. The National Transportation Safety Board has dispatched a 'go team' to investigate the collision. The incident has caused significant disruptions, with arriving planes being diverted to other airports or returning to their point of origin. New York's Emergency Management has warned of potential cancellations, road closures, traffic delays, and emergency personnel presence near the airport. LaGuardia Airport, which served 33.5 million passengers in 2024, has been experiencing flight disruptions due to poor weather and staffing impacts from a federal funding lapse.

The military campaign launched by the United States and Israel against Iran has entered its 24th day, bringing the region to a precarious juncture. As US President Donald Trump’s 48-hour ultimatum for Iran to reopen the Strait of Hormuz approaches its expiration at 23:44 GMT on Monday, Tehran has issued stern warnings regarding the potential targeting of its electricity grid. In response, Iran has vowed to strike the energy and water systems of its Gulf neighbors, raising fears of a broader regional energy crisis.The conflict is already having tangible repercussions on the global economy. Financial markets are reacting sharply to the escalating tensions, with stocks in China and Hong Kong on track for their worst performance in nearly a year. The uncertainty has fueled stagflation fears, prompting UK Prime Minister Keir Starmer to convene an emergency meeting to address the mounting economic fallout.In Iran, the situation remains volatile. The Israeli military has conducted a wide-scale wave of strikes targeting infrastructure across Tehran, resulting in powerful explosions reported in the central, southern, and eastern parts of the capital. Verified footage shows massive columns of fire and smoke rising over Karaj following an air attack. The Iranian Revolutionary Guard Corps (IRGC) has retaliated by threatening attacks on power plants in Israel and those supplying electricity to US bases, while also targeting a turbine engine production site in Qom used for drone components.The conflict has also spilled over into Gulf Cooperation Council (GCC) nations. Saudi Arabia’s Ministry of Defence confirmed that two ballistic missiles were launched toward Riyadh, with one intercepted and the other falling in an uninhabited area. The UAE reported debris injuries in the al-Shawamekh area, while Bahrain confirmed attacks on the US Fifth Fleet. In Qatar, seven people were killed in a helicopter crash, and Kuwait has formally protested airspace violations to the International Civil Aviation Organization.The human toll continues to rise. In Israel, alerts were triggered across Jerusalem and central Israel following explosions, with the casualty toll from attacks on Dimona and Arad climbing to at least 180 injured. In Lebanon, authorities report that at least 1,029 people have been killed since March 2, with over 100 of the victims being children. In Iraq, at least 60 people have been killed, primarily among pro-Iran Popular Mobilisation Forces.