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Health Apr 13, 2026

AI Breakthrough: Predicting Bowel Cancer Patients' Response to NHS Drug

Researchers have developed an AI-driven method to predict how patients with advanced bowel cancer w…
Scientists at London's Institute of Cancer Research and the RCSI University of Medicine and Health Sciences in Dublin have announced a new AI-driven approach to identify how patients with advanced bowel cancer will respond to bevacizumab, a drug recently introduced by the NHS. The method uses PhenMap, an AI tool that integrates complex data on the genetic makeup of tumors, allowing researchers to track patterns of how different patients react to the drug. This development aims to spare potentially thousands of patients from being given drugs that would be ineffective in fighting their cancers. In the UK alone, nearly 10,000 cases of advanced bowel cancer are identified every year, with young adults seeing a particular rise in diagnoses. Bowel cancer has the second-highest mortality rate of any cancer, behind only lung cancer. While survival rates can be as high as 98% when caught early, the five-year survival rate for advanced bowel cancer can be as low as 10%. The study tracked 117 European bowel cancer patients who had been treated with chemotherapy and bevacizumab. Researchers identified a group of patients who all had the same gene mutation and were at a high risk of having negative reactions. The scientists behind the tests now hope to expand the number of patient samples and see if the results can be used in treatments for other types of cancer. Anguraj Sadanandam, a professor in stratification and precision medicine at the ICR, said: “Once bowel cancer spreads to other parts of the body, there are very few treatment options available for patients. It is therefore positive that patients can now access the targeted drug bevacizumab on the NHS. However, we know that the majority of patients won’t benefit from the drug, meaning thousands of people in England could be facing unpleasant side effects unnecessarily.” Sadanandam added that while the findings were encouraging, the tool would need to be tested on a larger cohort to be validated. “In future, I hope this approach will lead to a test that can be used by clinicians, to ensure patients receive personalised care that has the highest chance of working against their cancer.”
#bevacizumab #NHS #bowel cancer
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Tv And Radio Apr 13, 2026

Guardian's Weekly Podcast Picks: History Fails, Bizarre News, True‑Crime Thriller, Celebrity Chat and Northern Quirks

The Guardian highlights five new weekly podcasts ranging from a history‑focused series that debunks…
History’s Greatest Fails pairs author Elizabeth Day with historian Dan Jones to explore celebrated historical missteps. After a witty reunion anecdote about their Cambridge days, the duo tackles the myth of Richard III’s villainy and promises a future episode on Henry VIII and Anne Boleyn, dubbed the "Ross and Rachel of early modern history."Strangely follows presenters Poppy Damon and Luke Jones as they plunge into off‑beat news stories, such as the macabre tale of a surgeon who amputated his own legs and the obscure origin of Neil Hopper’s "eunuch‑maker" moniker. The show balances factual depth with a tongue‑in‑cheek tone.Passenger Seat is a slow‑burn true‑crime podcast produced by Pennsylvania writer Tom Joudrey. The inaugural season recounts the 2012 kidnapping of Jennifer Hurst in Ohio, unraveling the puzzling motive behind the crime and the surprising gratitude she later expressed in court.Big Bro With Kid Cudi marks rapper Kid Cudi’s entry into the "celebrity podcast industrial complex". His first interview features Kylie Jenner, who drops the usual Kardashian PR veneer to discuss family dynamics, her upcoming acting role in the film The Moment, and a brief nod to Timothée Chalamet.Northern News reunites comedian Amy Gledhill with Ian Smith to spotlight odd and delightful headlines from the north of England that often slip under the radar. Regular contributors such as Stevie Martin, Alison Spittle and Phil Wang add extra comic flair.
#widely #available #episodes
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Sports Apr 12, 2026

City's 3-0 thrashing of Chelsea slashes Arsenal's lead and reignites title chase

Manchester City dismantled Chelsea 3-0 at Stamford Bridge, cutting Arsenal's nine‑point advantage t…
Manchester City delivered a decisive 3-0 victory over Chelsea at Stamford Bridge, a result that reduced Arsenal's nine‑point cushion to six and gave Pep Guardiola's side fresh impetus in the Premier League title race.City seized control early in the second half, with Nico O'Reilly heading in from a Rayan Cherki cross in the 51st minute. Six minutes later, Cherki’s incisive play produced a disguised pass to Marc Guéhi, who finished to make it 2-0. A third goal followed as a swift counter‑attack saw Cherki again on the ball, delivering a cross that O'Reilly converted, sealing the win.The match also highlighted individual milestones: Cherki notched his 10th league assist, becoming the first debutant since Dimitri Payet (2015‑16) to reach double‑digit assists in a Premier League season. Meanwhile, Guéhi recorded the first away player to keep two clean sheets at Stamford Bridge in a single campaign, having previously done so with Crystal Palace.Strategically, the win narrows the gap to Arsenal, leaving City six points behind with a game in hand. Should City overcome Arsenal at the Etihad this weekend, they could overtake the Gunners and re‑establish themselves as front‑runners for the title.Chelsea, hampered by the absence of injured captain Reece James and the suspension of Enzo Fernández, struggled to match City’s intensity. Their disciplinary record remains a concern, having amassed the league's highest number of yellow cards for dissent (16). Despite moments of promise from Cole Palmer, Pedro Neto and João Pedro, the Blues lacked the cutting edge in the final third and were out‑classed in midfield.Guardiola’s halftime adjustments proved pivotal; the team increased tempo, sharpened passing angles, and pressed higher, turning a sluggish first half into a dominant second‑half display. The victory not only restores confidence after a recent FA Cup win over Liverpool but also underscores City’s ability to respond swiftly to rivals’ slip‑ups, a pattern that has defined many of their recent title pursuits.
#Manchester City #Chelsea #Arsenal
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Sports Apr 12, 2026

Pep Guardiola’s Spring Surge: City’s 3‑0 Chelsea Win Narrows Title Gap with Arsenal

Manchester City’s dominant 3‑0 victory over Chelsea, highlighted by a early header from academy gra…
Manchester City delivered a commanding 3‑0 win at Stamford Bridge on April 12, 2026, a result that brings them within a single game’s reach of the league leaders, Arsenal. The victory, part of City’s impressive April record of 19 wins and 4 draws from 23 matches, underscores Pep Guardiola’s reputation as a spring‑time title avenger. The opening goal arrived in the 10th minute when Nico O’Reilly headed a close‑range effort past the Chelsea keeper, a moment described as a “free header” that ignited the Etihad‑like atmosphere among the travelling fans. Within the next 17 minutes, Marc Guéhi and Jérémy Doku added their names to the scoresheet, exposing a Chelsea defence that resembled a “shop‑worn bead curtain”. Guardiola’s side now sits six points behind Arsenal with a game in hand. A win at the Etihad next Sunday would reduce the deficit to three points, and a subsequent victory at Burnley could see the two clubs level on points, with City holding the superior goal difference. Arsenal, meanwhile, are grappling with a dramatic slump. After a nine‑point lead that seemed unassailable, the Gunners suffered a home defeat to Bournemouth, leaving them vulnerable to a potential “quadruple collapse” over the next sixteen days. City’s recent form has been nothing short of dominant: in their last three fixtures they have beaten the league leaders, the title‑holders, and the Club World Champions, scoring nine goals while keeping a clean sheet. The squad’s depth is evident, with five different scorers contributing to the tally. In contrast, Chelsea’s performance highlighted the widening gulf at the top of the table. Manager Liam Rosenior, still finding his footing after a mid‑season appointment, has yet to secure a win against the league’s elite, having lost to Guardiola, Luis Enrique and Mikel Arteta. Guardiola, ever the seasoned tactician, appeared composed even when Chelsea showed brief bursts of energy. His sideline attire—a practical anorak and brown shoes—mirrored his methodical approach, while midfield dynamo Bernardo Silva moved with the poise of a “captive prince” amid the chaos. As the season edges toward its climax, City’s blend of experience, tactical flexibility, and spring‑time confidence positions them as genuine title contenders. The next few weeks will determine whether Guardiola’s “alpha‑dog” energy can finally translate into the Premier League crown, or if Arsenal can rally to retain their lead.
#city #like #title
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Environment Apr 12, 2026

UK Gardens Losing Ground: RHS Finds 42% Paved Over as Conservationists Call for Wild‑Space Revival

A recent RHS audit reveals that 42% of Britain’s garden area has been concreted, sparking alarm amo…
Springtime in a typical British suburb is a chorus of birds, buzzing insects and the occasional rumble of a mini‑digger. While sparrows spar and tits clash over territory, a crew of contractors is often busy erasing hedges, bushes and trees, leaving behind a stark trench of bare earth. In one April afternoon, a once‑lush front garden was reduced to a skip full of uprooted branches and a strip of exposed soil. Despite the nation’s reputation as a garden‑loving society, the trend toward concrete is accelerating. An RHS audit published last year found that 42% of domestic garden space in the United Kingdom has been paved over, with timber fences replacing wild privet and driveways smothering mossy lawns. The loss is not merely aesthetic; it erodes habitats that support a remarkable share of the country’s wildlife. According to the Royal Horticultural Society, over 50% of Britain’s butterflies, amphibians and reptiles, and more than 40% of its bird and mammal species rely on garden habitats. The new David Attenborough series Secret Garden underscores this, describing urban gardens as “almost as diverse as a tropical rainforest.” Yet, as the series aired, another garden was being stripped to the ground, highlighting the tension between media‑driven reverence and on‑the‑ground reality. Socio‑economic factors compound the issue. One in eight households in the UK has no garden at all, and lower‑income families and ethnic minorities are disproportionately deprived of green space. Even owners of gardens often lack the time, money, or confidence to cultivate biodiverse oases, viewing gardening as a burdensome chore. Experts suggest a radical, yet simple, alternative: do nothing. Allowing dandelions, thistles, and stray grasses to flourish provides nectar for pollinators, while bare patches become nesting sites for bees and birds. Unraked leaves serve as winter shelters for insects, and dead stalks become food for aphids, which in turn feed higher‑up predators. The “negative space” of an untended garden can therefore become a hotbed of ecological activity. Conservationists argue that embracing this messiness could reverse the decline of urban biodiversity. As one commentator mused, “If Sir David Attenborough could return for a bonus episode, he might show us that a tangled, overgrown garden is not a failure but a vibrant ecosystem in its own right.” By Emma Beddington, 12 April 2026
#Royal Horticultural Society #UK gardens #wildlife refuges
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News Apr 11, 2026

Benin’s 2026 Presidential Vote Pits Economic Continuity Against Security and Democratic Concerns

Benin’s presidential election on April 12 will likely deliver a smooth transition to finance minist…
Benin is set to choose a new head of state on Sunday, April 12, 2026, in an election that appears to favor the governing coalition’s nominee, finance minister Romuald Wadagni. The 49‑year‑old, a former Deloitte executive, has been hand‑picked by outgoing President Patrice Talon, who is constitutionally barred from seeking a third term after a decade in power. With roughly eight million eligible voters on the rolls, the contest requires a candidate to secure more than 50 % of the vote; otherwise a runoff would be scheduled for May 10. In practice, only two names appear on the ballot: Wadagni, representing the Progressive Union Renewal‑Republican Bloc alliance, and Paul Hounkpe, the 56‑year‑old former teacher and culture minister who runs under the Cowry Forces for an Emerging Benin (FCBE) banner. Wadagni’s campaign emphasizes continuity of Talon’s economic reforms. Under Talon, Benin’s budget tripled and the country posted its strongest GDP growth in over twenty years, with the International Monetary Fund estimating a 7 % expansion in 2025. Investment in trade, agriculture and the Cotonou port has driven this performance, though benefits remain uneven, especially in the poorer northern regions. Security concerns dominate the northern frontier, where al‑Qaeda and IS‑linked militias from the Sahel have intensified cross‑border raids. Recent attacks by the JNIM network killed 54 soldiers in 2025 and another 15 in early 2026. A failed coup attempt in December 2025, allegedly motivated by neglect of troops in the north, left about 100 suspects awaiting trial. Wadagni has pledged to create municipal police forces to protect border towns, while Hounkpe warns that the current administration has sidelined citizens despite macro‑economic gains. Beyond economics and security, the election raises questions about Benin’s democratic health. Talon’s government has been criticized for suppressing protests, extending presidential terms from five to seven years, and enabling the president to appoint Senate members—moves that have effectively eliminated opposition representation. In the January parliamentary vote, Talon’s allies captured all 109 seats, and the main opposition party, the Democrats, failed to field a presidential candidate. Observers note that voter turnout will be a key barometer of public sentiment. The last presidential election saw only about 50 % participation. Al Jazeera reporter Ahmed Idris described the atmosphere at a governing‑party rally in Cotonou as “lively,” but cautioned that it may not reflect the broader mood in a nation where democratic space appears to be shrinking. Should Wadagni win, he pledges to build on a decade of “economic transformation,” expanding development hubs and healthcare access while maintaining fiscal discipline. Hounkpe, positioned as a moderate alternative, promises to lower basic commodity prices and secure the release of political prisoners detained under Talon’s rule. The outcome will shape Benin’s trajectory at a critical juncture: balancing sustained economic growth, confronting escalating security threats from the Sahel, and navigating the tension between authoritarian tendencies and the country’s reputation as one of West Africa’s more stable democracies.
#benin #talon #country
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News Apr 11, 2026

Israel Criticizes South Korea's President Over Video of Palestinian Abuse

Israel has criticized South Korean President Lee Jae Myung for sharing a video of Israeli soldiers …
Israel has criticized South Korean President Lee Jae Myung for sharing a video of violence against Palestinians by the Israeli army. The video, verified by Al Jazeera, shows Israeli soldiers pushing an apparently lifeless Palestinian man from a rooftop in the occupied West Bank town of Qabatiya in September 2024.Lee Jae Myung raised concerns about documented abuses committed by Israeli forces, posting on X: "I need to look into whether this is true, and if so, what measures have been taken." The Palestinian ministry of foreign affairs described the incident as a "crime" that exposes the Israeli army's "brutality".Israel's foreign ministry responded, saying the case had been "investigated and addressed", without providing details on any punishments for the soldiers involved. Data from Action on Armed Violence shows that Israel has closed 88% of investigations into abuses by its forces in Gaza and the occupied West Bank without charges or findings of wrongdoing.The incident has sparked a public row between Israel and South Korea, with Israel's foreign ministry accusing Lee of spreading "anti-Israeli" news. South Korea's foreign ministry attempted to ease tensions, saying Lee's comments reflected a broader appeal for "universal human rights".Lee doubled down on Saturday, responding to Israel's criticism with a pointed reply: "It's disappointing that you don't even once reflect on the criticisms from people around the world who are suffering and struggling due to relentless anti-human rights and anti-international law actions."
#israeli #israel #palestinians
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Features Apr 11, 2026

Makeshift ‘University City’ Revives Gaza’s Academic Life Amid Ongoing Siege

A US NGO has built a modest ‘University City’ in al‑Mawasi, Gaza, providing up to 600 displaced stu…
The new academic term began in Gaza in late March, but the usual bustle of students catching buses to campus has been replaced by the stark reality of displacement.Israel’s relentless campaign has turned most university buildings into rubble and shelters, forcing a shift to online learning that many students in tents cannot access due to lack of electricity, water, food and reliable internet.Against this backdrop, a glimmer of hope has emerged. In the overcrowded al‑Mawasi district of Khan Younis, the US‑based NGO Scholars Without Borders has erected a makeshift “University City,” a wooden and metal structure designed to bring students back into a real lecture hall."Our mission is to bring education closer to students in a better environment," said Hamza Abu Daqqa, the organisation’s Gaza representative.The facility houses six halls that can accommodate up to 600 students each day. Powered by solar panels, it offers internet access, improvised green spaces and even a small business incubator to help students explore entrepreneurial ideas.University City operates on a rotating weekly schedule, allocating each day to a different institution so that multiple universities can share the limited space. Priority is given to courses that require hands‑on instruction, such as practical labs and discussion‑based classes.Prominent Gaza institutions—including the Islamic University, Al‑Azhar University and the Palestine College of Nursing—have already begun using the site.For many students, this is the first time in years they have set foot in a space that feels like a real university. "When I saw this place, I was amazed," said 20‑year‑old nursing student Mariam Nasr, who fled Rafah and now travels four kilometres on foot to attend classes.Another first‑year student, Amr Muhammad, echoed the sentiment: "Being here with other students, discussing and engaging in class makes a huge difference."The broader picture remains grim. UN experts have labeled Israel’s systematic targeting of Gaza’s academic sector as “scholasticide.” More than 7,000 university students and staff have been killed or injured, and over 60 university buildings have been completely demolished, according to the Euro‑Med Human Rights Monitor.Materials for University City were sourced entirely within Gaza, a testament to the community’s resilience amid soaring costs and scarce resources. Yet the initiative is hampered by the same blockade that restricts reconstruction supplies, fuel and safe transport.Students still face daily hurdles: damaged roads, limited cash, and unreliable transport—often relying on worn‑out vehicles, donkey carts or long walks. "My father could only give me eight shekels (about $2.64) for a ride," Mariam explained, highlighting the economic strain.Even once inside the halls, challenges persist. Power outages and unstable internet make it difficult to print materials or follow online lectures, forcing many to rely on old phones and intermittent connections.Nevertheless, the atmosphere inside University City is one of determination. "For medical education, in‑person learning is essential," said Dr Essam Mughari of the Palestine College of Nursing. "Seeing students gather again restores something vital."For students like Mariam, the drive to continue studying is deeply personal. "My cousin, a nurse, was killed when an airstrike destroyed her family’s house. I study to heal others and honor her memory," she said.While University City now serves hundreds daily, thousands of Gaza’s students remain without comparable facilities. Abu Daqqa stresses that the project is only the beginning: "We have built dozens of makeshift schools, but the need is far greater. Imagine what could be done if the needed resources were allowed through."
#students #gaza #but
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Sport Apr 11, 2026

Mullins Makes History with I Am Maximus' Third Consecutive Grand National Win

Willie Mullins' horse I Am Maximus won the Grand National for the third consecutive year, marking a…
Willie Mullins has made the seemingly impossible look easy, securing his third consecutive win at the Grand National with I Am Maximus. This victory not only cements Mullins' reputation as a master trainer but also etches his name in the history books alongside Fred Rimell and Ginger McCain with his fourth Grand National win.The road to victory was far from straightforward. I Am Maximus, ridden by Paul Townend, faced significant challenges, including being blocked multiple times during the race. However, Townend's calm and strategic riding ultimately paid off, allowing I Am Maximus to secure a thrilling win.This achievement is all the more impressive given the challenging conditions. Mullins noted that this winter was the wettest he had experienced in 40 years, which made preparing his horses particularly difficult. Despite these obstacles, Mullins' team successfully primed I Am Maximus for the big event.The victory also marks a significant milestone for owner JP McManus, who has now secured his fourth Grand National win, a record. McManus expressed his admiration for Mullins and Townend, while also hinting at ambitions to equal Red Rum's legendary three consecutive National victories.Mullins, who will turn 70 in September, shows no signs of slowing down. He emphasized his passion for racing and his desire to continue building on his successes. With a clear focus on creating more history-making moments, Mullins and his team are already looking ahead to the next challenge.
#mullins #you #but
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