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The Plague, directed by Charlie Polinger, is a gripping debut feature that plunges into the psychological depths of a boy's water polo training camp in the summer of 2003. The film impressively captures the brutal hierarchy driven by braggadocio, bullying, hazing, and gaslighting among the young campers.The story follows Ben, a latecomer to the camp, played by Everett Blunck, who desperately tries to ingratiate himself with the cool crowd led by the impish Jake, played by Kayo Martin. Ben aims to avoid the pariah status of Eli, played by Kenny Rasmussen, who is supposedly afflicted with a made-up disease dubbed 'the plague' by the group.The film's stylistic bite is reminiscent of David Fincher's work, with a stunning initial submerged shot of a pool glittering like a starfield. Polinger also showcases a keen ear for the nonsense conversations among the 12-year-old campers, discussing topics such as 90s rock outfit Smash Mouth and the ethics of bestiality.While the film flirts with body horror, it never quite resolves its suggestion that the plague could be psychosomatic. Despite this, the young performers stand out in their unfiltered rawness, particularly Blunck, Martin, and Rasmussen. The film is a memorable education in the laws of the tween jungle, with Joel Edgerton providing a reassuring presence as Coach Daddy Wags.The Plague is set to be released on digital platforms from April 20, 2026.

New research indicates that individuals carrying the red‑hair allele have been evolutionary winners in Europe for more than 10,000 years. The study, led by Harvard scientists, examined DNA from nearly 16,000 ancient remains and over 6,000 living Europeans, providing robust proof that human biology continues to evolve long after farming began. Researchers identified 479 genetic variants that show clear signs of positive selection. Among these are genes linked to red hair and fair skin, as well as variants that affect susceptibility to coeliac disease, diabetes risk, baldness and rheumatoid arthritis. The authors suggest that the advantage of red hair may stem from its association with lighter skin, which enhances vitamin D synthesis in low‑sunlight environments—a crucial benefit for early European farmers. Prior to this work, only about 21 traits had been documented as having risen through natural selection, such as lactase persistence. The scarcity of earlier examples had led some to argue that directional selection was rare after modern humans left Africa. By leveraging an unprecedented volume of ancient genomic data and advanced computational methods, the team demonstrated that selection pressures intensified during the transition from hunter‑gatherer societies to agricultural ones, reshaping hundreds of genes across West Eurasia. "With these new techniques and the sheer scale of ancient DNA, we can now observe how selection sculpted our biology in near real‑time," said Dr. Ali Akbari, the study’s first author. Beyond vitamin D, the rise of certain disease‑related alleles poses intriguing puzzles. A mutation that heightens the risk of coeliac disease emerged around 4,000 years ago and has steadily increased, implying that carriers may have enjoyed other survival advantages despite the autoimmune threat. Similarly, the immune‑regulating gene TYK2, which markedly raises tuberculosis susceptibility, grew in frequency between 9,000 and 3,000 years ago before declining, hinting at a complex balance between pathogen defense and disease risk. The analysis also uncovered negative selection against genetic profiles that promote a high body‑fat percentage, supporting the classic “thrifty genes” hypothesis: traits advantageous for storing energy during scarce hunter‑gatherer periods became detrimental once agriculture ensured a steadier food supply. "This work lets us assign both place and time to the forces that have shaped us," noted Prof. David Reich, senior author and Harvard Medical School geneticist. While the findings are confined to West Eurasian populations, they raise broader questions about whether similar evolutionary dynamics occurred elsewhere. The full study appears in Nature.

Chris Walton, a renowned biologist and lecturer at Cranfield University, has passed away at the age of 69 due to brain cancer. He was widely respected for his pragmatic approach to getting things done and was often referred to as an honorary engineer by his colleagues.Walton's research focused on volatile organic compounds (VOCs) in various matrices, including breath, sweat, blood, urine, and faeces. He discovered links between specific VOCs and different human diseases, developing new methods to measure them. His work on environmental sensors, particularly low-cost air-quality monitors, was also notable.Born in Batley, West Yorkshire, Walton was the first in his family to attend university, graduating from Leicester University with a degree in biology in 1978. He later earned an MSc in biological computation at York University and a PhD from Coventry University.Walton's career spanned various institutions, including Imperial College London and EDS, an IT service provider. He joined Cranfield University in 1998 and became a lecturer in analytical technology. He was known for his sympathetic ear for students and his wise advice to younger colleagues.Walton is survived by his partner, Lorraine Morgan, and his daughter, Elizabeth.

The ongoing conflict between Israel and Iran has led to a substantial increase in global fuel prices, affecting Americans and forcing them to make difficult trade-offs. Many are struggling to access essential items, including medication and groceries, while others are facing financial insecurity and even homelessness.The impact of rising gas prices is being felt across various aspects of life, from accessing essential medicines to facing the brink of homelessness amid an already rising cost of living. For Mandy, a 42-year-old mother in central Utah, higher gas prices have made it harder to visit one of her children, who has disabilities and lives hours away.“Before [Donald] Trump and [Israeli prime minister Benjamin] Netanyahu started their war, gas in my town was $2.70 a gallon. Now it’s $4.19 and I’m terrified it’s going to go closer to $5 before all is said and done. One of our children is disabled and lives in a group home two and a half hours away,” she said.Rising gas prices are also affecting people’s ability to access necessary medication. Lisa, a 56-year-old living with disabilities on a tribal reservation in Oregon, said rising gas prices had disrupted her ability to access necessary medication.“My caregiver and I have had to cut back our trips to pick up my prescriptions, even though they are necessary. Because I live in rural Oregon, the basic necessities are 40 minutes away, so if a doctor calls in an additional prescription after I’ve already been in town for the week, that prescription has to wait for the following week for me to pick it up,” she said.The strain is also being felt by food banks and pantries. Melissa Meyer, chief executive of IPM Food Pantry in Cincinnati, Ohio, said rising gas prices had driven more people to rely on food pantries – even as those same costs strain the operations of local food banks and their volunteers.“Increased gas prices put additional costs on our operations as we must increase gas costs for picking up and delivering food across five counties of south-west Ohio … We are not cutting back our services in any way, yet,” she said.The rising cost of fuel is also having indirect effects, such as impacting small businesses and artists. Cathi Newlin, a 63-year-old ceramic artist in Sacramento, California, who also cares for her husband with Parkinson’s disease, said her income had been hit as consumers pull back.“A substantial portion of our household income is generated from the sale of my art and the classes I teach. These are surely luxury items in any economy but when people have to spend more on basics like gasoline, they don’t have as much money or desire to spend on art. The rise in oil prices very much affects my income and the price of my materials,” Newlin said.

Aaron Pierre delivers a storming, almost hypnotic performance as Randle P. McMurphy, instantly igniting the stale atmosphere of a 1960s American psychiatric ward. His swagger‑filled stride and sudden, childlike scampers create a compelling contrast that keeps the audience on edge.From the opening moments, McMurphy clashes with the authoritarian Nurse Ratched (Olivia Williams), provoking the other patients to rebel, play, and celebrate life beyond the ward’s walls. Pierre’s physicality—alternating between boisterous hugs and a frantic, vulnerable laugh—captures the character’s chaotic charisma.Director Clint Dyer, fresh from his acclaimed 2022 Othello, reshapes the narrative by casting the inmates almost entirely with Black actors. This choice injects a fresh political dimension, turning the patients into “pawns in a system designed to disempower.” Each time Ratched addresses them as “boys,” the line feels like an implicit sneer.While the script does not overtly discuss race—apart from Chief Bromden’s (Arthur Boan) Indigenous background—the production foregrounds the systemic misogyny embedded in both the novel and the 1963 Dale Wasserman adaptation. McMurphy’s mantra, “I fight and fuck,” teeters between liberated individualism and a problematic reclamation of alpha‑male tropes.Olivia Williams, who stepped into the role of Nurse Ratched late in rehearsals, gives the character a “ramrod spine and starched smile.” Her performance underscores the unchecked cruelty of a regime where the doctor (Matthew Steer) is a peripheral, snickering figure, leaving Ratched’s authority unchecked and increasingly vicious.Ken Kesey’s own experience as a government‑run LSD guinea‑pig informs the play’s visceral critique of psychiatry. The production’s lighting, designed by Chris Davey, erupts in scarlet and blue hues that echo the anti‑psychiatry movement of the 1960s, while the depiction of medication, group therapy, and electroconvulsive therapy feels deliberately brutal.Staged in the round at the Old Vic, the audience becomes a “ring of often appalled observers.” Ben Stone’s set design, with its white and pond‑green tiles beneath a soaring ceiling, creates a claustrophobic floor that simultaneously aspires upward—mirroring the characters’ yearning for freedom.The ensemble, led by Giles Terera’s refined Dale Harding, adds subtle layers of tension through nuanced tics and gestures. Dyer bookends the show with a reference to Congo Square in New Orleans, a historic site of Black and Indigenous resistance, framing the play’s cruelty through a lens of cultural resilience—though the production remains largely filtered through a male gaze.The production runs at the Old Vic until 23 May 2026, offering London audiences a bold, politically charged reinterpretation of a classic American drama.

For the first time, a detailed map identifies the UK’s most severe ammonia pollution hotspots in regions where intensive pig and poultry farms are most concentrated.The analysis, produced by Compassion in World Farming (CiWF) and the environmental group Sustain, shows the highest emission densities in Lincolnshire, Herefordshire and Norfolk. These counties host a large number of confined‑livestock units that drive dangerous levels of ammonia, a nitrogen‑based gas primarily released from animal manure.In the United Kingdom, agriculture accounts for 89% of national ammonia emissions. When released into the atmosphere, ammonia reacts with other pollutants to form fine particulate matter (PM2.5), a leading cause of premature death. The Committee on the Medical Effects of Air Pollutants (COMEAP) estimated that PM2.5 exposure caused between 28,861 and 29,000 early deaths in 2010.The timing of the report is notable: the government is currently reviewing planning regulations that would make it easier to approve new intensive livestock facilities, despite growing concerns over air quality, water contamination and local opposition.Health professionals warn that ammonia‑derived PM2.5 fuels heart disease, stroke, asthma and chronic lung conditions. Dr Amir Khan, a GP and CiWF patron, said, “As a GP, I see first‑hand the toll that air pollution takes on people’s health – and ammonia from intensive farming is a major, yet often overlooked, part of that problem.”Beyond human health, excess nitrogen from ammonia deposition acidifies soils and pollutes rivers. Recent activism in Shropshire halted a proposed poultry megafarm of 230,000 chickens after campaigners argued the council failed to assess the full environmental impact.Rising numbers of industrial poultry units—known as IPUs—along the River Wye and River Severn valleys are identified as a key driver of river pollution. Chicken manure is especially rich in phosphates, which deplete oxygen in waterways and threaten aquatic life.Calculations for the map were based on permitted stocking numbers and average ammonia production factors for different livestock categories, including broiler chickens, indoor egg layers and pigs.Local residents are already feeling the impact. Michele Franks, who lives near a Lincolnshire poultry megafarm, described how shed clean‑outs force her to stay indoors, causing “chest tightness, eye irritation and breathing difficulties” that can last for days.CiWF and Sustain are calling for an end to the expansion of factory farming. Anthony Field, head of Compassion in World Farming UK, warned, “Factory farming sits at the heart of the UK’s ammonia crisis. By cramming large numbers of animals into confined spaces and relying heavily on fertilisers, these intensive systems release far more ammonia than the environment or our bodies can cope with.”

The integration of artificial intelligence (AI) into various industries is revolutionizing the concept of 'creative destruction' in capitalism. This phenomenon, where outdated technologies are replaced by new ones, can be brutal, especially when machines exhibit cognitive skills, enabling them to think and learn. In an ideal scenario, policymakers would have ample time to adjust and mitigate the transition's impact. However, the current economic landscape, marked by weak growth and high energy prices due to the conflict in the Middle East, complicates matters. The closure of the Strait of Hormuz has led to shortages of raw materials and higher energy costs, which, coupled with the availability of labor-saving technology, could lead to rapid and large-scale job destruction. The Incentive to adopt machines over human labor will increase as businesses seek to cut costs amid economic uncertainty. The International Monetary Fund's recent downgrade of growth forecasts and warnings of a global recession further exacerbate this trend. As a result, companies will be more inclined to adopt AI, potentially leading to a significant rise in unemployment. While AI optimists argue that new technologies will create more jobs than they destroy in the long run, there are concerns that this time may be different. The impact of AI could be more transformative and disruptive than previous technological advancements. Moreover, there's a risk that the jobs destroyed by AI may be better paid than those created, potentially leading to a decline in living standards. The article concludes that the future depends on whether AI will enhance or replace human jobs. Policymakers have a narrow window to prepare their economies and societies for the challenges posed by AI, focusing on reskilling, reindustrialization, and redistribution. Failure to act quickly may result in the benefits of AI being captured by a small minority, while the majority faces the consequences of mass unemployment.

German director Christian Petzold, known for his elegant and disquieting films, presents 'Miroirs No 3', a psychological mystery that delves into the complexities of grief and family dysfunction. The film, starring Paula Beer as Laura, a talented pianist struggling with depression, navigates the aftermath of a sudden violent trauma.The story takes a fascinating turn when Laura, who survives a catastrophic car crash, meets Betty, an intense and enigmatic woman, played by Barbara Auer. Betty's character is shrouded in mystery, and her relationship with Laura becomes increasingly complex. As Laura becomes entangled in Betty's family dynamics, the film masterfully crafts an atmosphere of tension and unease.Petzold's direction weaves a narrative that eschews macabre twists and instead, steers towards a redemptive conclusion. The film's use of Maurice Ravel's Miroirs, particularly the third movement 'A Boat on the Ocean', adds a dreamlike quality to the proceedings. This subtle touch showcases Petzold's skill in creating an elegantly contrived study of an unhappy family group.The performances, particularly from Beer and Auer, bring depth to the film's exploration of emotional trauma and the complexities of human relationships. As the story unfolds, the audience is left questioning the characters' motivations and the true nature of their interactions. 'Miroirs No 3' is a thought-provoking and hauntingly beautiful film that solidifies Petzold's reputation as a master of modern European cinema.

Japan has taken a significant step in its foreign policy by easing its arms export rules, marking a departure from its eight-decade-long pacifist stance. This move comes as trust in US President Donald Trump declines, with him wavering on security commitments to allies and involvement in conflicts in Iran and Ukraine.The Japanese government has approved a record defense budget of $58 billion for 2026, reflecting a push to strengthen military and coastal defenses amid rising global tensions. The new budget forms part of a broader $784 billion national budget for the fiscal year beginning in April 2026.Under the new budget, over $6.2 billion is earmarked to enhance Japan's 'standoff' missile capabilities, including the purchase of domestically produced and upgraded Type-12 surface-to-ship missiles. This move is seen as a response to China's growing military presence in the Asia-Pacific region.Japan's key defense contractors, Toshiba and Mitsubishi Electric, are hiring staff and adding capacity to capitalize on demand for arms. Countries such as the Philippines and Poland are expected to become customers of Japanese arms.The easing of arms export rules is part of Japan's efforts to shape its own security policy and reduce its military dependence on the US. This shift is driven by the need to build defense supply chains in Asia that do not rely on the US, particularly in light of Washington's preoccupation with wars in the Middle East and Ukraine.Japanese companies are eager to boost sales by selling their products abroad, with Toshiba planning to hire 500 people over the next three years and constructing new testing and manufacturing facilities. The company's vice president, Kenji Kobayashi, noted that 'reputational risk is not what it used to be.'The US has welcomed Japan's initiatives to boost defense spending and take regional security into its own hands, with US Secretary of Defense Pete Hegseth praising Japan's investment in its defense capabilities.