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A recent court of appeal decision suggesting it's impossible to determine which identical twin fathered a child has sparked controversy among genetics experts. Prof Michael Krawczak from Kiel University, Germany, argues that this is not the case. According to Krawczak, the germ cells of monozygotic twins differ with sufficient probability and to a sufficient degree to allow their respective children to be clearly assigned to either of them using molecular genetic techniques.Krawczak and his colleagues first proposed this approach in 2012 and demonstrated its practical feasibility in 2018. While the required molecular genetic testing is costly, currently in the five-figure range, Krawczak questions whether these costs would be a significant enough barrier to preclude genetic testing, given the potential consequences of inaction for those involved.The court's assertion that it was "not possible" to determine paternity in such cases is therefore disputed. Krawczak's comments highlight the potential for genetic testing to resolve paternity disputes in cases involving monozygotic twins, offering a solution to a complex and sensitive issue.

Conversations about mundane topics are often dreaded, but research suggests that people enjoy them more than they anticipate. A study involving 1,800 volunteers found that participants enjoyed chatting about dull subjects, such as the stock market or vegan diets, more than they expected. The findings indicate that by avoiding potentially dull exchanges, individuals may miss out on the mood boost and health benefits that come with connecting with others. Elizabeth Trinh, a PhD candidate in management and organisations at the University of Michigan, noted that people tend to underestimate how interesting and enjoyable conversations about boring topics can be. Trinh and her colleagues conducted a series of experiments to gauge how people responded to conversations on dull topics. Participants were asked to predict how much they would enjoy discussing topics they considered boring, and then engage in brief conversations about those topics. The results, published in the Journal of Personality and Social Psychology, showed that people consistently found the conversations more enjoyable than they expected. The surprise enjoyment arises because individuals base their expectations on static components, such as the topic and the other person, rather than dynamic components, like the conversation itself. Trinh suggests that people may benefit from lowering the bar for what makes a conversation worth having and reframing conversational goals. Instead of focusing on enjoyment, individuals could think about what they might learn from the conversation. Nicholas Epley, a professor of behavioural science at the University of Chicago, added that the fear of a boring conversation shouldn’t prevent people from starting one. “If a conversation is boring once you’re in it, you also have a surprising amount of power to make it better!”

Recent CDC data reveal a dramatic 1,200% increase in kratom‑related poisonings across the United States over the last ten years, with the most pronounced surge recorded in 2025. Researchers link this rise to the growing presence of 7‑hydroxymitragynine (7‑OH), a synthetically produced compound that mimics kratom’s effects but carries opioid‑like risks. Walter Prozialeck, pharmacology professor at Midwestern University, said the trend was expected, noting that the synthetic alkaloid has entered the market through energy drinks and other products since 2024. Christopher McCurdy of the University of Florida warned that marketing 7‑OH as “enhanced kratom” blurs the line for consumers, turning poison‑control calls into a conflated metric for both natural and synthetic products. By contrast, natural kratom (Mitragyna speciosa)—a Southeast Asian plant used for centuries as a pain reliever—has demonstrated a relatively favorable safety profile in animal and human studies. A 2018 statement from then‑HHS Secretary Brett Giroir rejected the DEA’s push to schedule kratom as a Schedule I substance, citing insufficient evidence of harm. Despite the scientific distinction, several states have moved to implement or propose blanket bans on all kratom products, prompting concern from clinicians and patient advocates. A recent user survey indicated that about 50% of respondents rely on kratom for chronic pain, while roughly 40% use it during addiction recovery. Personal testimonies underscore the plant’s therapeutic role. Jeff Maslan, a 68‑year‑old Californian with severe osteoarthritis, credits kratom with easing opioid withdrawal after multiple surgeries. Similarly, “Steven,” a disabled California resident, describes how kratom eliminated unbearable oxycodone withdrawal symptoms without producing the euphoric “warm fuzzy” feeling typical of opioids. Researchers emphasize that 7‑OH carries genuine opioid hazards, including addiction, severe withdrawal, and respiratory depression that can lead to fatal overdose. In animal models, 7‑OH demonstrated the same respiratory‑depression risk as classic opioids, whereas kratom’s primary alkaloid did not. Prozialeck and colleagues explain that kratom’s pharmacology is more nuanced: it partially activates opioid receptors while also engaging adrenergic and serotonin pathways, resembling a hybrid of a weak opioid and an SNRI‑type antidepressant. This multimodal action likely accounts for its lower euphoric potential and the reported boost in energy among users. Nevertheless, experts caution that kratom is not without risk. Fatal poisonings often involve co‑ingestion of potent opioids such as fentanyl, suggesting that some users may cycle between kratom and stronger substances, raising overdose danger due to reduced opioid tolerance. Additionally, heavy‑metal contamination has been detected in certain kratom batches, though the source—soil, processing, or storage—remains unclear. Given these complexities, the consensus among scholars like Austin Zamarripa (Johns Hopkins) is that natural kratom should remain accessible, while concentrated 7‑OH products merit stricter regulation. “These products may offer meaningful benefits to some individuals, and those benefits could be lost if access is restricted too broadly,” Zamarripa said, urging a differentiated policy approach. As the debate unfolds, patients like Steven worry that a sweeping ban would ignore the nuanced safety profile of the plant. “There’s corn on the cob, there’s high‑fructose corn syrup, there’s whiskey— all derived from corn but fundamentally different,” he remarked, highlighting the need for targeted, evidence‑based regulation rather than a one‑size‑fits‑all prohibition.

The recent 10-day space mission of the Artemis II crew has garnered attention, but the true test of endurance might not be in space, but in an office setting. Commander Reid Wiseman, mission specialists Christina Koch and Jeremy Hansen, and pilot Victor Glover spent time in a capsule described as “not much bigger than a family tent”. While they navigated the challenges of confined space, their experience pales in comparison to the complexities of office politics.Anyone who has worked in an office can attest that surviving with colleagues in a confined environment is a significant test of endurance. The Artemis II crew had to get along without time off, which would be challenging even for experienced professionals. The quirks and habits of colleagues can become amplified in such settings, leading to increased tension and stress.The writer of this piece reflects on their own experience in a mundane office job at a stationery firm. They recall the boredom and impotence that led to a fixation on trivial matters, such as a dispute over a window being open or closed. This petty feud became an all-consuming battle that defined their time at the office.The writer notes that, unlike the Artemis II crew, they had the option to leave the office at the end of the day. However, their obsession with the window dispute led them to spend more time at their desk, avoiding breaks and social interactions. The comparison between the crew's space test and the writer's office experience highlights the universal challenges of working with others.Ultimately, the Artemis II crew's achievement is impressive, but it also underscores the importance of interpersonal skills and conflict resolution in any confined or high-stress environment. As the writer concludes, surviving an office job can be just as challenging as surviving in space.

Eamonn Holmes, the 66‑year‑old presenter of GB News’s breakfast programme, is recovering in hospital after suffering a stroke last week.A GB News spokesperson confirmed that the Northern Irish broadcaster is responding well to treatment and has requested privacy while focusing on his recovery. The network added that “his colleagues and everyone at GB News wish him a speedy recovery and look forward to welcoming him back when he is ready.”In Holmes’s absence, the channel said that Alex Armstrong will co‑anchor the morning slot alongside Ellie Costello for the coming week.Holmes, who previously fronted ITV’s This Morning and co‑presented with his former wife Ruth Langsford for 14 years, has a documented history of serious health issues. He has undergone spinal surgery, a double hip replacement, and endured multiple falls, including a live on‑air incident when a studio chair collapsed.Speaking about that on‑air fall, Holmes recalled, “It was a bit of a shock for me because I’d had a fall in my bathroom two weeks earlier that hospitalised me, and it hit me again right in the back.” He described the aftermath as “really, really sore.”His health struggles have also impacted his personal life. In 2022, Holmes told the Sun that chronic pain and mobility problems strained his marriage to Langsford, and he later disclosed a dislocated pelvis in 2021 that led to three slipped discs.Holmes is now in a relationship with 44‑year‑old counsellor Katie Alexander. The pair were photographed together at a recent event, with Holmes using a wheelchair.GB News chief executive Angelos Frangopoulos expressed support, stating, “Eamonn is a loved member of the GB News family, and we’re with him every step of the way as he recovers.”

It's been a year since the Trump administration's sweeping cuts to the federal workforce, and the effects are still being felt. Tens of thousands of employees were offered buyouts or faced termination, leaving many to navigate a difficult job market. Maggie, a former employee of the US Office of Personnel Management, took a buyout offer in May 2025. She has since applied to over 250 jobs but is still waiting for an ethics letter to start work elsewhere. 'I couldn't be without health insurance through the delivery of my baby,' she said, highlighting the challenges faced by those who lost their jobs. The federal workforce has declined by about 355,000 employees since Trump took office, with 18,000 workers leaving in March 2026 alone. The cuts have left remaining government workers overwhelmed, trying to keep essential public services afloat. Charles Melton, a 20-year veteran of the US Department of Agriculture, took early retirement but still helps former colleagues with job applications. 'I'm still mad as hell,' he said. 'We just got thrown away like garbage.' The impact on public services has been significant, with customer service at the Social Security Administration worsening and healthcare workers at the Department of Veterans Affairs reporting ongoing staffing issues. The shutdown of USAID has resulted in hundreds of thousands of deaths worldwide due to the spread of infectious diseases and malnutrition. The White House has declined to comment, but Scott Kupor, OPM's director, stated that 'reshaping the federal workforce is essential to building a government that works for the American people, not the bureaucracy.'

Oil tanker workers stuck in the Gulf for six weeks are reaching their limit, with mental health concerns escalating due to the prolonged standoff. A crew member, who spoke to the Guardian, revealed that the situation is becoming increasingly unbearable.The worker, one of 20,000 seafarers trapped by Iran's chokehold on the Strait of Hormuz, expressed frustration and despair, stating that any hope of being freed had evaporated. The crew member's tanker is anchored near dozens of loaded tankers, with many feeling unwilling and unable to traverse the strait, even if a ceasefire allowed them to do so.90% of the crew on the tanker want to exercise their right to refuse to sail, citing safety concerns. The situation has taken a toll on the crew's mental health, with one member suffering a 'mental breakdown' and being checked on regularly by colleagues.The International Transport Workers' Federation (ITF) has received about 1,000 inquiries from seafarers on 300 different vessels, with 20% seeking repatriation. The union and other organizations are trying to provide support, but the situation remains dire.The shipping companies are expected to find new crew members willing to work in hazardous areas, offering double pay and promotions. However, the workers stuck on the tankers hope that their vessel will be taken to anchorage to allow new crew to take their places.The situation has reignited calls for shipowners to replace their crews with mariners willing to offer relief, highlighting the human cost of the conflict.

A Network Rail worker has emerged victorious in a race harassment case after his colleagues left an anti-Islam English Defence League (EDL) leaflet in his locker. Parmjit Bassi, based at Eastleigh depot in Hampshire, was found to be a victim of a racist attack when a co-worker stuffed the EDL leaflet in his locker, questioning what individuals were doing to protect their children from Islam.The leaflet, produced by the far-right group EDL, asked questions that implied a threat to the worker, regardless of his religious background. Bassi, who is not a Muslim, was also accused of committing a high-profile stabbing when colleagues placed a newspaper page in his locker about a knife attack.The Southampton employment tribunal ruled that the incidents were 'clear slights' against Bassi's race and that Network Rail managers had a 'laissez-faire attitude' towards them. The tribunal concluded that the company's inaction was 'weak management' that only strengthened the bullies' position at the expense of Bassi.Bassi successfully sued Network Rail and is now in line to receive compensation. The case highlights the importance of addressing workplace bullying and racial harassment. The tribunal's decision emphasizes that racial harassment can occur even if the victim does not belong to the targeted group, in this case, Islam.The incidents led to Bassi being moved to a different team and eventually dismissed in April 2021. He appealed against the decision but it was upheld, leading him to take Network Rail to the employment tribunal with claims of racial harassment and unfair dismissal, both of which were successful.

President Donald Trump issued a stark warning that the United States would eradicate Iran’s “civilisation” unless the regime reopens the Strait of Hormuz and complies with his demands. The statement, posted on his Truth Social account less than twelve hours before the self‑imposed deadline, declared that a whole civilisation could die “tonight, never to be brought back again.” Trump set the cutoff for compliance at 8 p.m. Washington time (00:00 GMT) on Tuesday, framing the moment as a decisive point in what he called a long‑standing struggle against Iranian extortion and corruption. For more than two weeks, the president has threatened to strike Iran’s civilian infrastructure—bridges, power stations, roads and other non‑military assets—if his terms are not met. Legal analysts have warned that such actions would constitute a war crime under international law. “It’s horrific. It’s pure evil. It’s disqualifying,” said Yasmine Taeb, legislative and political director of MPower Change Action Fund, condemning the president’s rhetoric as that of “a deranged, unstable madman.” She called for a stronger response from both U.S. lawmakers and the global community. Democratic leaders reacted forcefully. Senate Majority Leader Chuck Schumer labeled Trump “an extremely sick person,” while House Minority Leader Hakeem Jeffries urged Republican colleagues to “put patriotic duty over party and stop the madness,” warning that the conflict could spiral into a world war. Representative Rashida Tlaib suggested invoking the 25th Amendment to remove Trump, citing the recent bombing of a school in Minab that killed over 170 children. Congressional attempts to curb the president’s war powers have stalled; a recent resolution to limit his authority failed to pass, leaving the legal basis for the campaign in question. Critics argue that launching a military operation without congressional approval violates the U.S. Constitution, which reserves the declaration of war to Congress. Republican reactions were muted. Representative Mike Lawler downplayed the threat, stating that any strikes would target only Iran’s energy and civilian infrastructure to cripple the regime’s economy, and affirmed that Trump is acting within his constitutional authority as commander‑in‑chief. The conflict, which began on February 28 when the United States and Israel allegedly killed Iranian Supreme Leader Ali Khamenei and other senior officials, has already claimed more than 2,000 lives, including civilians in schools, residential blocks and medical facilities. Iran’s retaliatory rocket and drone attacks have hit Israeli and U.S. assets across the Middle East, while Iranian forces have blocked the Strait of Hormuz, driving global energy prices higher. Despite the heavy toll, Iran’s governing structure appears intact, bolstered by the Islamic Revolutionary Guard Corps, designated by the United States as a terrorist organization. No major defections or anti‑government protests have emerged, and Khamenei’s son, Mojtaba Khamenei, has assumed a leading role. Trump, while maintaining a hardline stance, left a narrow window for diplomacy, suggesting that “maybe something revolutionary wonderful can happen.” He framed the deadline as “one of the most important moments in the long and complex history of the world,” promising that “47 years of extortion, corruption, and death will finally end.” Vice President J.D. Vance echoed the president’s message, warning Iran that the United States possesses additional, undisclosed tools and will employ them if Tehran does not alter its conduct, emphasizing the U.S. desire for free flow of oil and gas.