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The conflict that erupted in April 2023 between Sudan’s army and the Rapid Support Forces has driven the country’s humanitarian situation to catastrophic levels, according to the international non‑governmental organisation Humanity & Inclusion.Three years on, the NGO warns that civilians are enduring a deepening crisis, while people with disabilities are confronting extreme challenges as violence continues, essential services crumble, and unexploded ordnance spreads across former battle zones.Humanity & Inclusion estimates that 11.6 million Sudanese have been displaced by the fighting, and that **more than 33 million people now require humanitarian assistance**—roughly half the nation’s population. By the end of January 2026, over **3 million displaced individuals had begun returning home**, including **700,000 who had fled abroad**. Most of these returns have been to states where hostilities have eased, such as Khartoum, the Blue Nile and Gezira regions.The organisation highlights that **4.6 million Sudanese—about 16 % of the total population—live with disabilities**. In conflict‑affected areas this proportion is likely higher due to war‑related injuries, trauma, and deteriorating health conditions. The NGO stresses that disabled persons “face extreme challenges in fleeing violence, accessing aid, and protecting themselves from harm,” and are often among “the first to be left behind,” exposing them to heightened risks of violence, abuse, discrimination and exclusion.Adding to the peril, Humanity & Inclusion points to the lingering presence of **explosive remnants of war**, describing them as a “new and deadly danger” for millions returning to their homes. Unexploded ordnance—including antipersonnel mines—has contaminated former front lines, residential areas, schools, hospitals, places of worship and roadways, severely restricting access to essential services and livelihoods.These findings underscore the urgent need for intensified humanitarian response, targeted protection measures for people with disabilities, and comprehensive clearance of explosive hazards to prevent further civilian casualties and enable the safe return of displaced populations.

A tragic incident unfolded early on Thursday off the northern coast of France, near Calais, as four people died while attempting to board an inflatable dinghy to cross the English Channel to the UK. The group of migrants waded into the sea to reach a small boat positioned offshore, but things went wrong, and they struggled in the water.Christian Fourcroy, the mayor of Equihen-Plage, confirmed that two women and two men lost their lives in the incident. A fifth person remains in a critical condition. Emergency services launched a rescue operation along the coastline between Equihen and Ecault, France, and 38 other people were rescued, including one with a medical emergency.The Boulogne prosecutor has opened an investigation into the deaths. This incident is part of a surge in attempted crossings and deaths in recent days. French maritime authorities reported rescuing 102 people in two separate operations on Wednesday while trying to cross the channel. Just last week, two people died in a similar incident off the coast north of Calais.Despite heightened enforcement efforts by France and the UK, 4,776 people crossed the channel between January 1 and April 4 this year, following over 41,000 crossings in 2025. The UK remains a destination for many undocumented migrants due to family ties, language, and the prospect of work. However, the journey is frequently perilous, with overcrowded boats and unpredictable conditions putting lives at risk.The issue has intensified political debate across Europe, with Paris and London seeking to deter crossings through a 'one in, one out' scheme, allowing some migrants to enter the UK legally in exchange for the return of others who arrive by boat. Rights groups argue that such measures fail to address the root causes driving people to risk the journey, emphasizing the need for safer pathways to be created.

Lebanon has declared a national day of mourning following a devastating wave of Israeli attacks that killed at least 254 people and injured over 1,165 in a single day. Prime Minister Nawaf Salam has mobilized 'all of Lebanon's political and diplomatic resources to stop the Israeli killing machine.'Israeli Prime Minister Benjamin Netanyahu stated that Lebanon is not part of the ceasefire between the US and Iran, a position echoed by US Vice President JD Vance, who said, 'We never made that promise.'Pakistani Prime Minister Shehbaz Sharif, who mediated the ceasefire, claimed the deal included a pause in fighting in Lebanon. However, Iran's Foreign Minister Abbas Araghchi warned that Washington must choose between a ceasefire or 'continued war via Israel,' emphasizing that it 'cannot have both.'Iranian President Masoud Pezeshkian said a halt to Israeli attacks in Lebanon was a key condition of Iran's 10-point plan for securing an end to the Middle East war. However, a US official stated that Iran's published ceasefire plan is not the same set of conditions agreed on by the White House.US Vice President JD Vance will lead the country's delegation for talks with Iran in Pakistan, while French President Emmanuel Macron has urged that Lebanon be included in the ceasefire as the 'best path to peace.'The conflict has also affected the Gulf region, with Kuwait, UAE, Qatar, Saudi Arabia, and Bahrain reporting damage and disruptions from Iranian strikes. The situation remains volatile, with Israel's Prime Minister Netanyahu stating that Israel is prepared to 'return to battle' if necessary.

President Donald Trump declared on Truth Social that U.S. troops, aircraft and naval vessels will stay positioned around Iran until what he termed the "REAL AGREEMENT" is fully honored, warning that any failure by Tehran will trigger "bigger, better, and stronger" military action.Trump’s message, posted late Wednesday, underscores Washington’s demand that Iran abandon any nuclear weapons ambitions and guarantee safe passage through the strategically vital Strait of Hormuz. He added that U.S. forces are "loading up and resting, looking forward to its next conquest," a rhetoric that heightens concerns of a rapid escalation.The announcement follows a two‑week ceasefire brokered by Pakistan that paused six weeks of combat and briefly steadied global markets worried about disruptions to oil shipments through Hormuz. However, the truce remains precarious.Iranian semi‑official outlets ISNA and Tasnim released a chart suggesting the Islamic Revolutionary Guard Corps (IRGC) had laid sea mines in the strait, marking a "danger zone" that forced some vessels to navigate farther north near Larak Island. The chart, dated Feb. 28 to Apr. 9, leaves it unclear whether the mines have been cleared.On the ground in Tehran, public sentiment is deeply skeptical. One woman told Al Jazeera that any day without bloodshed would be "very good," while another dismissed the ceasefire as meaningless while Israel continues its bombardment of Lebanon. A third resident called the truce "a theatrical show" orchestrated by Trump.Negotiations are further complicated by Tehran’s rejection of a sweeping U.S. proposal. Iran insists on an end to Israeli attacks on Lebanon and the lifting of sanctions—conditions Washington has yet to accept.Despite the uncertainty, Iranian officials hinted at a diplomatic push: Ambassador Reza Amiri Moghadam announced on X that a delegation would arrive in Islamabad for talks based on ten Iranian‑proposed points, though he later deleted the post. Pakistan’s capital simultaneously announced two days of unannounced holidays, adding to the opacity.Israel has intensified its campaign in Lebanon, killing at least 182 people in a single day, which Tehran warns could render further negotiations "unreasonable" under the current circumstances.In Washington, opposition to the conflict is mounting. Senator Cory Booker announced that Democrats intend to invoke the War Powers Resolution to force a congressional vote, condemning Trump’s actions as "unauthorised" and "reckless war‑mongering" that the American public does not support.The convergence of U.S. military posturing, Iranian skepticism, Israeli escalation, and domestic political pressure creates a volatile environment where the fragile ceasefire could unravel, threatening regional security and global energy markets.

In a stark address delivered as the cease‑fire in the Iran conflict teetered, IMF Managing Director Kristalina Georgieva warned that the war will leave a permanent scar on the global economy, slowing growth beyond the IMF’s original projections for 2026. Georgieva noted that, had the hostilities not erupted six weeks ago, the Fund would have been poised to raise its 2026 growth outlook. Instead, even the most optimistic scenario now entails a downgrade, and a swift return to pre‑war conditions appears unlikely. The uncertainty surrounding the cease‑fire—exacerbated by divergent positions of Washington and Tehran—has already pushed oil prices higher, reflecting fears of continued disruptions to shipments through the Strait of Hormuz, a vital conduit for world energy supplies. According to the IMF’s upcoming World Economic Outlook, the conflict’s “scarring effects” will translate into lower living standards worldwide. The Fund had previously forecast global growth of 3.1% in 2026, a modest slowdown from 3.2% in 2025, buoyed by a tech‑driven investment surge. Georgieva emphasized that the war arrived when the economy was riding “considerable momentum” from technology investment and supportive financial markets. She outlined the mechanisms of damage: damaged infrastructure, supply‑chain interruptions, eroded confidence, and prolonged uncertainty over oil and gas production in the region. These factors will depress growth regardless of whether a peace agreement is ultimately reached. Georgieva highlighted that the most vulnerable will be net oil‑importing nations, poorer economies and small island states, which stand to feel the brunt of higher energy costs and reduced trade flows. She urged governments to avoid unilateral measures such as export bans or price controls, warning that such actions could "pour gasoline on the fire" and further destabilise markets. With many countries already carrying elevated debt levels and higher borrowing costs, the IMF chief called for targeted, temporary assistance to protect the most at‑risk households. She cautioned against broad tax cuts or blanket energy subsidies, which could stoke inflation and strain fragile public finances. Central banks, she added, should keep policy rates steady while remaining ready to act against inflationary pressures. Bank of England Governor Andrew Bailey, who also chairs the Financial Stability Board, echoed the IMF’s concerns, describing the conflict as a "very big shock" that has heightened market volatility. He stressed that the situation remains fluid and that policymakers must stay vigilant. Overall, the IMF’s message is clear: the Iran war will reshape the global growth trajectory for the foreseeable future, and coordinated, prudent policy responses are essential to mitigate its lasting impact.

Israel's attacks on Lebanon have intensified, with the country launching its largest and most destructive attack on Lebanon in years, killing at least 300 people and wounding over 1,100. The attacks have sparked widespread panic and overwhelmed hospitals in the Lebanese capital, Beirut.The escalation has significant implications for the US-Iran ceasefire, which was agreed upon just days ago. Iranian leaders are accusing the US of failing to uphold the truce and threatening to back out of it unless Washington restrains its ally, Israel. 'The U.S. must choose – ceasefire or continued war via Israel. It cannot have both,' Iran's foreign minister, Abbas Araghchi, wrote on Twitter/X.The conflict has been fueled by Netanyahu's actions, who has sought to expand the conflict out of Gaza and into a wider war with Hezbollah in Lebanon. The Israeli prime minister has undermined ceasefire talks and blocked potential deals, adding new conditions or changing his mind at the last minute. 'There is no ceasefire in Lebanon,' Netanyahu said in a recorded message, as Israel continued its attacks.The situation is volatile, with Hezbollah showing it is not as weak as Israel and the US had thought. The militia has fought pitched battles with invading Israeli troops and fired hundreds of rockets and drones at northern Israel. The conflict has forcibly displaced over 1.1 million people, many of whom are living on the streets.

A 47‑year‑old woman who had endured three life‑threatening autoimmune diseases for more than a decade is now living a near‑normal life after an experimental CAR‑T cell therapy reset her immune system at University Hospital Erlangen in Germany.Before the procedure she had exhausted nine different treatments with no lasting benefit, relying on daily blood transfusions and continuous anticoagulation to manage her illnesses.Within weeks of the infusion, doctors observed rapid improvement in all three conditions—a world‑first outcome. She has remained in treatment‑free remission for 14 months and has largely returned to everyday activities.Prof Fabian Müller, who led the team, called the speed and depth of the response “remarkable” and said the therapy “significantly improved her quality of life.” He emphasized that clinical trials are required to determine how durable the effect is and whether it can help other autoimmune patients.The patient suffered from three distinct disorders: autoimmune haemolytic anaemia (AIHA), where rogue immune cells destroy red blood cells; immune thrombocytopenia (ITP), which depletes platelets and raises bleeding risk; and antiphospholipid syndrome (APS), which promotes dangerous blood clots. All three stem from malfunctioning B‑cells.With no conventional options left, doctors turned to CAR‑T therapy, a technique that has revolutionised treatment for certain cancers. They harvested her white‑blood cells, isolated the T‑cells, engineered them to recognise the CD19 protein on B‑cells, and reinfused the modified cells.The engineered T‑cells swiftly eliminated the pathogenic B‑cells. She received her last blood transfusion a week after treatment and was able to perform routine tasks within two weeks. Follow‑up tests showed a reconstituted, healthy B‑cell population, suggesting an immune reset. The findings were published in the journal Med.She still exhibits a mildly low white‑cell count and slightly elevated liver enzymes, which researchers attribute to the cumulative impact of prior therapies rather than the CAR‑T product.Rheumatology expert Prof Ben Parker of Manchester University NHS Foundation Trust described the case as encouraging, noting that “the prolonged response off normal therapy suggests there has been an immune reset.” However, he warned that case reports alone cannot confirm efficacy and highlighted ongoing trials for lupus, myositis, multiple sclerosis, systemic sclerosis, vasculitis, and other autoimmune conditions.

The recent two-week ceasefire announced by US President Donald Trump in the war on Iran has sent shockwaves through Israel. The move has been met with criticism from Israel's opposition leader, Yair Lapid, who called it one of the greatest 'political disasters in all of our history'. Prime Minister Benjamin Netanyahu's office issued a statement supporting the US decision, claiming that 'Iran no longer poses a nuclear, missile and terror threat to America, Israel, Iran's Arab neighbours and the world.' However, Netanyahu's war aims of preventing 'Iran from developing nuclear weapons' and creating 'the conditions for the Iranian people so they can remove the cruel regime of tyranny' remain unachieved.Despite significant military successes over the past 40 days of attacks on Iran, neither of Netanyahu's goals has been achieved. The Iranian regime is still in place, its ballistic missile programme could be rebuilt quickly, and it still has 440kg of enriched uranium at 60 percent purity, enough for 10 bombs.Analysts say that Iran has emerged stronger as a result of the war, with key victories including the survival of the Iranian government and its decision to close the Strait of Hormuz, one of the world's key energy arteries. The ceasefire has also given Iran an opportunity to continue with newly imposed levies on ships for safe passage through the Strait.Criticism of Netanyahu's handling of the war has been swift, with Ofer Cassif of the left-wing Hadash party saying that the prime minister has 'failed politically, failed strategically, and didn't meet a single one of the goals that he himself set'. Ahron Bregman, a senior teaching fellow at the Department for War Studies at King's College London, said that 'Israel achieved almost nothing tangible' and that the ceasefire has 'strained the US relationship'.

Celebrations erupted in Tehran after officials announced a two‑week ceasefire with the United States, creating a window for diplomatic talks aimed at de‑escalating the regional conflict.Iran consented to suspend hostilities, with negotiations slated to begin on Friday in Pakistan. President Donald Trump pledged to halt military operations provided Tehran fully reopens the Strait of Hormuz, a vital maritime corridor. Iran’s foreign minister added that safe passage through the strait will be coordinated with Iranian armed forces throughout the truce.The breakthrough followed a direct appeal by Pakistan’s Prime Minister Shehbaz Sharif, who urged Trump to extend his negotiation deadline and called on Iran to restore strait access.Iranian officials framed the ceasefire as a “victory”, asserting that their preconditions for talks were accepted and that Trump’s acknowledgment of progress on key disputes validates Tehran’s stance. They emphasized that national unity, patience, and military resilience were decisive factors.In their assessment, the earlier U.S.–Israeli strategy of targeting Iranian leadership failed, while the ensuing conflict demonstrated Iran’s capacity to sustain prolonged military operations.Trump, speaking to AFP, described the agreement as a “total and complete victory”, insisting that Iran’s uranium stockpiles would be “perfectly taken care of” under the deal and crediting China for facilitating the negotiations.Despite the truce, Democratic lawmakers announced they will continue impeachment efforts against Trump, condemning his rhetoric toward Iran as “genocidal” and “unhinged.”