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The Lead The World Health Organization (WHO) has approved the first malaria treatment for babies, marking a significant milestone in the global fight against the disease. Coartem Baby, developed by Novartis and the Medicines for Malaria Venture (MMV), is designed for infants as small as 2kg (4.4lb) and comes in sweet cherry-flavoured tablets that can be dissolved into liquids, including breast milk. The Event Details Coartem Baby contains two antimalarial drugs, artemether and lumefantrine. The treatment has been shown to be safe and effective for newborns and young infants, addressing a critical gap in malaria care. According to the WHO, up to 18% of children under six months in parts of Africa are infected with malaria, but there has historically been no safe treatment for the smallest of them. The Data Analysis Malaria remains a significant public health challenge, particularly in sub-Saharan Africa. In 2024, there were 610,000 deaths from malaria, about three-quarters of which were under-fives in Africa. The approval of Coartem Baby is expected to significantly impact malaria treatment and prevention efforts, particularly in regions with high rates of malaria. The Impact Analysis The introduction of Coartem Baby is a major breakthrough in the fight against malaria. Dr Tedros Adhanom Ghebreyesus, the WHO director general, noted that "for centuries, malaria has stolen children from their parents, and health, wealth and hope from communities." The approval of this treatment offers new hope for communities affected by malaria and brings the global health community closer to achieving its goal of eliminating the disease. The Prediction With the WHO prequalification of Coartem Baby, public-sector procurement of the treatment is expected to increase in many countries with high rates of malaria, particularly in sub-Saharan Africa. Novartis has committed to making the treatment available "on a largely not-for-profit basis in malaria-endemic regions." As more countries introduce Coartem Baby into their health systems, the impact on malaria-related mortality and morbidity is expected to be significant.

The Marathon Match that Defined the WeekendLeeds Rhinos demonstrated remarkable resilience in a bruising encounter against Wakefield Trinity, securing a win that extends their unbeaten run. The match, which lasted well over two hours, was marred by a serious head injury to Wakefield's Cameron Scott, necessitating a lengthy stoppage in the early stages. Despite being reduced to 12 men on the field at various points due to sin-bins for Sivo and Ash Handley, Leeds held firm.Maika Sivo's Historic Scoring RateFijian winger Maika Sivo delivered a performance of sheer dominance, claiming a hat-trick that brings his season tally to 17 tries in just nine Super League games. His clinical finishing was the difference maker, with half-back Jake Connor providing the service. Sivo's efficiency places him among the elite goal-kickers of the modern era, making him a focal point of Leeds' attacking strategy.Connor's Case for England: A World Cup StatementWhile Sivo grabbed the headlines, Jake Connor's influence was equally pivotal. Providing four try assists, Connor orchestrated Leeds' attack with precision. His performance serves as a powerful rebuttal to his omission from last year's Ashes series, putting immense pressure on new England coach Brian McDermott to select him as the starting scrum-half for the Rugby League World Cup.Leeds Rhinos: The Title Contenders' ResilienceBrad Arthur's side has now won 8 of their last 10 games, keeping them ahead of St Helens on points difference. The victory underscores a growing trend: Leeds is not just winning, but winning ugly when necessary. Their ability to withstand Wakefield's fightback and maintain composure under pressure suggests they are the team to beat in the current Super League season.

Mikel Arteta dismissed the notion that Premier League clubs cannot match the quality of European giants after Bayern Munich and Paris Saint‑Germain produced what he called “the best game of the season” in their Champions League semi‑final.Arteta’s Benchmark: Bayern vs PSG as the Gold StandardSpeaking after Arsenal’s recent 2‑1 defeat to Manchester City, the manager highlighted the “night‑and‑day” contrast between the German and French sides and the English league. “When I look at that game, Bayern v PSG, it’s probably the best game I ever witnessed in the quality of two teams… but when I look at the amount of minutes and the freshness of those players, then I’m not surprised,” he said.Freshness vs. Fixture Congestion: The Numbers Behind Arsenal’s Squad HealthInjuries: Kai Havertz (muscle), Jurriën Timber (muscle), Martin Ødegaard (knee doubt)Upcoming fixtures: Premier League match vs Fulham (Saturday), Champions League second‑leg vs Atlético Madrid (following week)Player availability: Arteta noted that PSG and Bayern fielded “all of them, at their very best” whereas Arsenal are missing several key figures.Implications for the Premier League: A Growing Competitive Divide?Arteta’s comments suggest a widening gap caused by deeper squads and fewer injuries among Europe’s elite clubs. If English sides cannot maintain comparable fitness levels, their ability to compete on both domestic and continental fronts may be compromised, potentially reshaping transfer strategies and squad rotation policies.Looking Ahead: Arsenal’s Path to Closing the GapArteta believes a win over Fulham could put Arsenal six points clear of Manchester City, but stresses that “having every player available and fit at their best” remains the decisive factor. He expects Havertz to return for the Atlético clash and hopes Gabriel Magalhães avoids suspension, aiming to blend freshness with tactical consistency to challenge the “different worlds” narrative.

The LeadPremier League news updates from around the league, including Tottenham's injury crisis, Liverpool's improving form, and Manchester United's upcoming clash with Liverpool. De Zerbi on Spurs' Injury CrisisRoberto De Zerbi has ruled out Dominic Solanke for Sunday's trip to Aston Villa and is unsure if the striker will feature again in Tottenham's battle against relegation. De Zerbi emphasized that victory over Villa would not be a 'miracle' and doubled down on his belief that the club will stay up. Slot on Liverpool's Improving FormArne Slot expects Alexander Isak and Florian Wirtz to drive Liverpool forward after seeing significant contributions recently. The two most expensive signings in the club's history have had largely underwhelming first seasons, but Slot believes they are finally starting to find their feet. Carrick on Manchester United vs LiverpoolMichael Carrick says Manchester United's meeting with Liverpool on Sunday is a 'different ball game', irrespective of where the clubs stand in the table. Carrick insists any clash between the country's two most successful clubs remains a big draw. The Data Analysis Tottenham have 8 players out injured, including Solanke and Xavi Simons. Liverpool's Isak and Wirtz have scored 7 goals and 10 assists between them this season. Manchester United are third in the table with 61 points, three points ahead of Liverpool. The Impact AnalysisThe Premier League relegation battle is heating up, with Tottenham, Nottingham Forest, and other teams fighting to stay up. Liverpool and Manchester United's clash on Sunday could have significant implications for the top-four race. The PredictionTottenham's victory over Villa would not be a 'miracle', according to De Zerbi. Liverpool's improving form could see them push for a top-four finish, while Manchester United's win over Liverpool could boost their own top-four hopes.

Lead: Why this match mattersLeeds United host Burnley at Elland Road on 8pm BST, a fixture that could cement Leeds' Premier League survival or plunge them back into a relegation battle. Burnley, already relegated and without a permanent manager, are fighting for pride in their final top‑flight game.Leeds' safety hopes versus Burnley's relegation battleBoth clubs earned promotion last season with exactly 100 points in the Championship, yet their trajectories have diverged dramatically. Leeds sit on 40 points, double Burnley's tally, and are just above the safety line. Burnley remain at the bottom with no points from recent matches and are managed on an interim basis by Mike Jackson.Numbers on the board: points, fixtures and oddsLeeds United: 40 points after 36 gamesBurnley: 20 points (approx.) and already relegatedLeeds' remaining tough fixtures: away at Spurs and West HamKick‑off time: 20:00 BSTImpact on the Premier League landscapeA Leeds win would likely secure their place for another season, reducing the pressure on clubs fighting the drop and shaping the final table. Conversely, a loss could see Leeds dragged into a relegation scrap for the first time in 23 years, a rare occurrence for a 40‑point side. For Burnley, a victory would be a morale boost but would not alter their relegation fate, highlighting the stark contrast between survival battles and end‑of‑season formality.Looking ahead: possible scenariosIf Leeds claim three points, they move to 43 points, putting them comfortably above the drop zone. A draw keeps them at 41 points, still likely safe but dependent on other results. A loss forces Leeds into a must‑win situation in their final two games. Burnley, regardless of outcome, will finish the season with a managerial transition and will need to regroup for the Championship campaign.

Lead: A jam‑packed weekend of live sport across the UK and beyondThe Guardian’s weekend guide promises nonstop action: Premier League clashes that could reshape the title race, County Championship cricket battles, a high‑stakes 2,000 Guineas at Newmarket, the return of Formula One in Miami and a decisive Women’s Champions League semi‑final.Saturday’s marquee fixtures: football, cricket, horse racing and F1Football (8am‑12pm BST): Premier League match‑day live coverage, with key games such as Ipswich v QPR, Millwall v Oxford and Wrexham v Middlesbrough shaping promotion and relegation.Cricket (11am): County Championship day two, featuring Surrey, Leicestershire, Glamorgan, Yorkshire, Northamptonshire and Derbyshire.Horse racing (11.30am): 2,000 Guineas at Newmarket – Bow Echo and Gstaad lead a 15‑runner field.Formula One (5pm & 9pm): Miami Grand Prix returns after a five‑week hiatus, with new regulation tweaks under scrutiny.Data analysis: Numbers that matter for titles and betsKey statistics highlighted include:Newcastle sit 14th after four straight defeats, raising questions over Eddie Howe’s future.West Ham sit two points ahead of 18th‑placed Tottenham, three behind Nottingham Forest and four behind Leeds United.Arsenal need a win over Fulham to push six points clear of Manchester City.Max Verstappen called recent car changes a “tickle”, hinting at possible driver market movement.Impact analysis: How the outcomes could reshape leagues and championshipsVictories in Saturday’s football fixtures could cement promotion hopes for clubs like Wrexham while deepening relegation battles for others. In cricket, the drawn County Championship matches may prompt a review of the points system, potentially increasing the reward for outright wins. The Miami Grand Prix will test whether regulatory changes improve racing spectacle, influencing F1’s global audience and sponsor confidence. Arsenal’s Women’s Champions League win over Lyon puts them in a strong position for a first title since 2016.Prediction: What to watch for in the coming weekExpect intense Premier League drama on Sunday with Bournemouth v Crystal Palace, Manchester United v Liverpool and Aston Villa v Tottenham—all likely to impact the top‑four race. In cricket, day three of the County Championship will be crucial for teams still seeking their first win. The Women’s Champions League second leg in Lyon will decide if Arsenal can clinch the trophy. Finally, the Miami Grand Prix’s regulatory tweaks will be judged by lap times and fan reaction, setting the tone for the rest of the F1 season.

Lead: The Final Weekend Holds the Keys to PromotionThe last round of fixtures sees three clubs locked in a high‑stakes race for the Championship’s two promotion spots. Ipswich Town must beat QPR to stay in the driver’s seat, while Millwall and Middlesbrough need victories and a favourable result elsewhere to keep their dreams alive.Final‑Day Showdown at Portman Road, The New Den and BeyondSaturday’s lunchtime fixtures pit Ipswich against 14th‑placed QPR at Portman Road, Millwall host relegated Oxford United at The New Den, and Middlesbrough travel to Wrexham. The matches are set to decide whether the clubs ascend to the Premier League or endure another season in the second tier.Points, Goal Difference and the Mathematics of PromotionIpswich Town sit on 89 points with a +5 goal‑difference advantage over Middlesbrough.Millwall are on 87 points, two behind Ipswich, and must win to stay within reach.Middlesbrough have 88 points but a -5 goal‑difference deficit that makes a win essential.A draw for Ipswich drops them to 90 points; Millwall would need a win to reach 90 and hope Middlesbrough slip.What Promotion Means for the Clubs and the ChampionshipFor Kieran McKenna’s Ipswich Town, a return to the Premier League would mark his third promotion in four and a half years, cementing his reputation as a promotion specialist. Alex Neil’s Millwall aim to end a 36‑year exile from the top flight, a narrative that could boost the club’s commercial profile and fanbase. Kim Hellberg’s Middlesbrough seek to restore a recent Premier League stint, preserving the investment made in the squad and avoiding the financial hit of another season in the Championship.Scenarios for the Final Whistle and BeyondIf Ipswich win and both rivals drop points, Ipswich secure automatic promotion.If Ipswich draw and Millwall win, Millwall leapfrog into second place on goal difference.If Ipswich lose, a win for either Millwall or Middlesbrough could hand them the second spot, with goal difference deciding the order.Should all three win, Ipswich finish top, Millwall second, and Middlesbrough miss out.Regardless of the outcome, the drama underscores the Championship’s reputation for delivering nail‑biting finishes and highlights the fine margins that separate promotion glory from another year of second‑tier football.

In a war‑torn Ukrainian city, a concrete deer shaped like folded paper has become a beacon of hope, now en route to the 2026 Venice Biennale. The piece, created by Zhanna Kadyrova, has travelled from the frontlines of Pokrovsk through Paris, Warsaw, Prague, Vienna and Brussels, gathering stories of survival and a new mythology along the way. A Concrete Deer Becomes a Symbol of Hope The sculpture was first installed in 2018 on a plinth that once held a Soviet Su‑7 bomber in Pokrovsk, Donetsk region. Intended as a simple, touchable landmark for locals, it later turned into a poignant reminder of peace when the city fell under Russian fire. From Eastern Ukraine to UNESCO: The Deer’s Epic Overland Journey In August 2024, as combat approached, curator Leonid Marushchak coordinated the risky evacuation of the deer, using angle grinders, a hammer drill and a crane to free it from its concrete base. The sculpture was then loaded onto a flat‑bed truck and began a circuitous tour of European capitals, stopping at UNESCO’s Paris headquarters before heading to Venice. Timeline and Logistics: Numbers Behind the Relocation 30 August 2024 – Deer lifted from its plinth in Pokrovsk. September 2024 – March 2025 – Transported through Warsaw, Prague, Vienna and Brussels. April 2025 – Displayed in UNESCO gardens, alongside Alexander Calder’s Spirale. May 2025 – Arrived in Venice, docked in the lagoon for the Biennale. Distance covered: roughly 2,500 km across five countries. Why the Deer Resonates: Cultural and Political Impact The deer now embodies a “new mythology” for displaced Ukrainians. Visitors—refugees, locals and tourists—touch the sculpture and make wishes, turning a public art piece into a living memorial of a city that may soon be reduced to rubble. Its presence at UNESCO underscores the intersection of cultural heritage protection and wartime loss, while the Biennale’s decision to host both Ukraine and a reinstated Russian pavilion adds a fraught political layer. What Lies Ahead: The Deer’s Role at the 2026 Venice Biennale Featured in the Ukrainian pavilion titled Security Guarantees, the deer will serve as a visual metaphor for the displacement of millions of Ukrainians. Curators hope the work will shift the conversation from a binary “anti‑Russian” narrative to a broader reflection on survival, cultural continuity, and the power of art to travel beyond borders. As the Biennale progresses, the deer’s journey may inspire similar cultural rescue projects across conflict zones.

Undefeated super‑bantamweight champion Naoya Inoue will face fellow unbeaten rival Junto Nakatani in a sold‑out, high‑profile bout at the Tokyo Dome on 2 May, a fight many are calling the biggest in Japanese boxing history.A Historic Showdown at the Tokyo DomeThe press conference on Thursday revealed both fighters entering with perfect 32‑0 records and multiple‑weight world titles. Inoue, the 33‑year‑old “Monster,” has captured world belts at 108 lb, 115 lb, 118 lb and 122 lb, while Nakatani brings a three‑inch height edge, a one‑inch reach advantage, and a southpaw stance that could pose new challenges.Inoue: 27 KO wins, 205 rounds boxed, 5 ft 5 in, 121.92 lb, 67½ in reach, orthodox.Nakatani: 24 KO wins, 164 rounds boxed, 5 ft 8 in, 121.47 lb, 68½ in reach, southpaw.Financial Stakes: Inoue’s Earnings and the Economics of Japanese BoxingTicket demand was extraordinary – 55,000 seats sold out almost instantly and over 100 cinemas across Japan booked out for live screenings. While exact purses remain undisclosed, Sportico reported Inoue’s 2025 earnings at roughly ¥9.7 bn ($62 m) including endorsements. His previous Tokyo Dome appearance in May 2024 generated over ¥1 bn in commercial revenue, suggesting Saturday’s payday could eclipse even his lucrative Saudi bout.Cultural Ripple: Boosting Boxing’s Profile in JapanThe fight has captured national attention, with major sports dailies dubbing it 「世紀の一戦」 (“Fight of the Century”). Local celebrations, such as the City Border Challenge festival in Kanagawa, underscore the event’s grassroots excitement. Inoue hopes the bout will draw new fans, describing it as an opportunity to “engrave my fighting spirit in your memory” and showcase boxing’s excitement to a broader audience.What the Outcome Could Mean for the Sport’s FutureIf Inoue prevails, his dominance could cement his legacy as the sport’s premier draw, attracting more high‑profile events to Japan and increasing sponsorship opportunities. A victory for Nakatani would shake the pound‑for‑pound hierarchy, potentially opening a new era of rivalry and expanding the market for Japanese fighters abroad. Either scenario promises to reshape the commercial and cultural landscape of boxing in the region.