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The LeadWhen Keir Starmer won a landslide Labour majority promising to pursue five governing "missions", the high-profile leftwing economist Mariana Mazzucato was credited as an inspiration. Two years on, her bracing new book helps shed light on why Labour in power has struggled to project the sense of direction that "mission-led government", as Mazzucato calls it, requires.A New Framework for Economic PolicySynthesising and extending her earlier work, here she proposes "a new economics of collective action around the common good". From this perspective, the economy is not a concatenation of rapacious independent forces, to be contained and offset by public policy, but a project – or rather a series of projects – with direction and purpose.The Five Principles of Common Good EconomicsThe "compass" in the title is really a set of five principles, all of which Mazzucato says such an economy should have: purpose and "directionality"; co-creation by citizens; collective learning; reward sharing; and accountability. Each of these principles is set out in detail. Co-creation implies grassroots participation in designing and redesigning government programmes, for example – because, "when people help define a problem and develop and implement solutions, they see them as theirs rather than something imposed on them".Reward Sharing and PredistributionReward sharing means ensuring the creators or rightful owners of economic value stand to benefit: from Indigenous people whose homes lie near raw material deposits, to social media users whose data fuels Big Tech's profits. That implies radical tax reform – including greater use of wealth taxes – and the robust use of conditions in public contracts, to make sure workers and taxpayers get their fair share: an approach she calls "predistribution".Critique of Labour's Economic ApproachAccording to Mazzucato's definition, Labour's attempt at mission-led government badly missed the mark. Its first and overriding goal – "kickstart economic growth" – cannot be a "mission" at all, because it lacks the necessary purpose. What, in other words, is that economic growth meant to be for? While her scope in this ambitious book is global, the analysis also dismantles Starmer's claim to be pursuing national "missions", by setting out just how radical – and radically different – that would look in practice.Practical Examples and Global Applications"The seeds of transformation are everywhere," she says, citing inspiring projects that range from delivering healthy and sustainable school meals in Sweden to the EU's mission to support cities to become climate-neutral, to the international Nagoya Protocol on sharing the benefits of genetic resources and traditional knowledge. Echoes of Mazzucato's mindset are detectable in some Labour policies – from using the threat of legislation to cajole pension funds to invest more in UK assets, to writing conditions on youth training into clean energy contracts.The Future of Economic DirectionEconomies work best, she believes, when they pursue grand collective goals – developing and distributing a vaccine for a pandemic; or confronting the climate emergency (or, though she doesn't lean on the example here, tooling up for a new and more frightening geopolitical era). We should ask, she says, "not which market failure do we want to be fixed, but what direction do we want the economy to sail in".

The Lead: A Record-Breaking CareerJames Milner has etched his name into football history by breaking the Premier League appearance record, a remarkable achievement that speaks volumes about his longevity, consistency, and unwavering dedication to the sport. The 40-year-old veteran has demonstrated an extraordinary level of professionalism throughout his career, earning admiration from teammates and rivals alike for his commitment to excellence both on and off the pitch.The Professional Profile: Beyond Ordinary DedicationFormer teammates paint a picture of a player who was exceptional from his early days. Michael Bridges, who roomed with Milner during his time at Leeds, recalls: "James Milner was the most dedicated and professional young player I've met. He also took the not inconsiderable transition from being at school to playing in the Leeds first team totally in his stride. Nothing fazed him. He was very level-headed."This level-headedness extended to Milner's lifestyle choices. While teammates socialized with alcoholic drinks, Milner remained steadfast in his commitment to peak physical condition, often opting for Ribena Toothkind instead. His dedication was so complete that teammates nicknamed him the "hydration monster" due to his intense focus on maintaining optimal hydration levels.The Technical Mastery: Versatility Across PositionsWhat sets Milner apart is not just his longevity but his remarkable versatility. Throughout his career, he has excelled in multiple positions, adapting his game to suit different tactical systems and managerial philosophies. Bridges notes: "Above all he's a very intelligent footballer who reads the game well and has the versatility to play in different positions for different types of managers. That's helped him."This adaptability has allowed Milner to remain relevant across different eras of football evolution. From his early days at Leeds to his current role, he has consistently demonstrated an ability to read the game and position himself effectively, even as the tactical demands of the sport have evolved.The Impact Analysis: Redefining ProfessionalismMilner's career offers a fascinating case study in modern professionalism. In an era where footballers often face intense scrutiny and shorter careers, Milner has bucked the trend through his extraordinary discipline and commitment. Steve Harper, who worked with Milner at Newcastle, draws a direct comparison: "His level of professionalism is right up there with Cristiano Ronaldo's. It's no coincidence that they're both still going strong."This approach has had ripple effects throughout the sport. Younger players now have a role model for how to maintain peak performance over an extended career. Milner's career demonstrates that longevity in professional football is not merely about talent but about lifestyle choices, work ethic, and mental fortitude.The Legacy: More Than Just AppearancesAs Milner surpasses Gareth Barry's previous record of 653 Premier League appearances, his legacy extends far beyond the numbers. Curtis Davies, who played with Milner at Aston Villa, emphasizes: "Breaking the appearance record will be testament to him and the way he has lived his life, and if anyone is going to go past Gareth Barry, another former Villa teammate, there's no better person than James to do so."Milner's career represents a different kind of greatness in modern football—one built on consistency, adaptability, and unwavering professionalism rather than just fleeting moments of brilliance. As he continues to add to his record, he stands as a testament to the values that can sustain a career at the highest level for more than two decades.

FCA has begun a 12‑week trial with US data‑analytics firm Palantir to test AI‑driven crime detection, while MPs and privacy groups warn the partnership could give the Trump administration a backdoor to UK financial data under the US Cloud Act.Details of the FCA‑Palantir AI trialThe trial will see Palantir’s platforms applied to a wide range of FCA data sets, including case intelligence files, lender fraud reports, consumer complaints and social‑media monitoring. The arrangement is at the 12‑week pilot stage and is intended to improve the regulator’s ability to spot financial crime.Financial stakes and contractual backdrop$375bn valuation of Palantir, co‑founded by Trump‑supporting billionaire Peter Thiel.Palantir holds contracts worth over £500m with NHS England and the Ministry of Defence.London mayor Sadiq Khan blocked a separate £50m two‑year deal between Palantir and the Metropolitan Police.Legal and sovereignty implicationsCritics argue that under the US Cloud Act, US authorities could compel Palantir to hand over any data it processes, potentially exposing UK citizens’ financial information to US surveillance regimes such as the Patriot Act and FISA. The FCA maintains that Palantir is only a “data processor”, that all data remains encrypted, and that the regulator retains control.Potential impact on UK data policyIf the trial proceeds without robust safeguards, it could set a precedent for further reliance on US‑based AI vendors, eroding confidence in the UK’s data sovereignty and prompting stricter procurement rules. Conversely, a successful pilot could accelerate AI adoption across UK regulators, influencing future contracts with private tech firms.Outlook and next stepsParliamentary committees are expected to request a detailed legal review of the Cloud Act’s applicability. The FCA has pledged to publish trial results, but pressure from MPs like Martin Wrigley suggests additional oversight may be imposed before any wider rollout.

Summer Arrival Brings Noctilucent Clouds to the Night SkyAs the northern‑hemisphere summer settles in, a rare high‑altitude spectacle lights up the western twilight: noctilucent clouds, or “night‑shining” clouds, glow with an electric‑blue hue just after sunset.High‑Altitude Glows at the Edge of SpaceThese formations sit at roughly 80 km above the surface—virtually the edge of space—making them the highest known clouds in Earth’s atmosphere. They become visible about half an hour after sunset, when the lower atmosphere is in shadow but the thin upper layer still reflects sunlight.Numbers Behind the PhenomenonTypical altitude: 80 kmFirst documented sighting: 1885Key historical event coinciding with appearance: 1885 Krakatoa eruptionSouthern‑hemisphere season start: around OctoberResearchers note that no recorded observations exist before 1885, despite the clouds’ striking visibility, prompting theories that they may be linked to industrial aerosols emerging in the late 19th century.Why Noctilucent Clouds Matter for Climate ScienceThe clouds serve as a natural laboratory for studying upper‑atmospheric processes. Possible drivers include:Industrial pollutants providing nucleation sites for ice crystals.Volcanic eruptions (e.g., Krakatoa) injecting particles into the mesosphere.Climate‑induced increases in water vapour reaching higher altitudes.Because their brightness and frequency respond to subtle changes in mesospheric temperature and composition, noctilucent clouds are increasingly viewed as a proxy for monitoring climate‑related shifts.Future Outlook: Monitoring Upper‑Atmosphere ChangesScientists plan to combine satellite lidar measurements with ground‑based observations to track seasonal trends and assess whether cloud frequency intensifies under a warming climate. Continued study will help determine if noctilucent clouds can act as an early‑warning indicator for broader atmospheric transformations.

The Global Bauxite Rush and Guinea's ContradictionIn the small village of Bembou Silaty, northwestern Guinea, 38-year-old Mamadou Aliou embodies the central contradiction of Guinea's bauxite boom. Working in the environmental health and safety department for a mining company while simultaneously advocating for his community's rights, Aliou represents the complex relationship between global resource demands and local realities."Before these companies arrived, we cultivated our land, and it sustained us," Aliou told Al Jazeera. "We could cover our daily needs, especially food. But now, when a piece of land is registered and belongs to a mining company, you have nothing there any more."The Strategic Value of Guinea's Bauxite ReservesGuinea holds the world's largest reserves of bauxite, the ore that becomes alumina and ultimately aluminum—a metal essential for car and aircraft frames, windows, wind turbines, and solar panels. Over the past three decades, the country has multiplied its bauxite production tenfold, with more than a dozen ongoing projects currently operating.As the global energy transition demands ever more aluminum, Guinea has found itself in a strategically crucial position. Approximately 75 percent of the bauxite exported by the country over the past decade has ended up in China, which produces 60 percent of the world's aluminum. Companies from Russia, the United States, and the United Arab Emirates have also established significant operations in the country to secure this valuable resource.Economic Disparities and Compensation ChallengesIn the traditional bauxite heartlands of Kindia and Boke, the main roads are notably well-maintained, and steady jobs in technical roles or transport logistics have created economic opportunities for some Guineans. In Bembou Silaty, however, the situation remains starkly different—a quiet village without electricity, where farming methods remain untouched by mechanization.People working in technical roles at the mine can earn up to about $300 a month, a significant sum in Guinea. For other locals who make a living from farming, most don't have a regular wage and rely on the yield from their crops. Across Guinea, an estimated half of the population depends on agriculture for their livelihood.Locals in Bembou Silaty say every hectare claimed by mining is a hectare lost to farming, in a country that spent more than $500m importing rice in 2024. "They give you compensation for your land, but it's not enough, and in the end, it's mismanaged," Aliou said. "Within a month or two, someone who received 50 or 100 million Guinean francs ($5,700-11,400) has nothing left. No land, no money. They have to start over, from below zero."Environmental Degradation and Water ContaminationThe environmental impact of bauxite mining in communities like Bembou Silaty has been profound. Not all homes in the village of about 5,000 have indoor toilets and plumbing. While a new water point serves nearly all residents, the water contains iron contamination.In neighboring villages, the situation is even more dire. "Since the mining companies came, we've had this problem with the water. The children get sick, and the parents too," said Mariama Kindi Diallo, a farmer. "The doctors tell us not to drink the rain or river water. There are no roads, no school, no phone signal. What are we supposed to do? We are asking for help to have a dignified life."Environmental concerns extend beyond water contamination. Surgical holes drilled into the ground mark where mining companies have tested for bauxite—a reminder to farmers that the impact on the land is felt even before extraction begins. In a recent report, Djami Diallo, the Guinean minister of the environment and sustainable development, stated that each year, certain companies had their impact studies and evaluation reports rejected for failing to comply with environmental standards.The Government's Push for Value AdditionTo address these challenges and increase the benefits for Guinea, the government of Mamady Doumbouya, which came to power in a 2021 coup, is attempting to reorganize the mining sector. It is pressing investors to process bauxite within Guinea, ensuring a portion of the value stays in the country.Processing bauxite into aluminum can multiply its price by 37 times. Instability in Iran amid the US and Israel's war has contributed to rising aluminum prices, which surpassed $3,600 per tonne in April. Doumbouya is set to lead the country for the next seven years, after winning the December 2025 elections with nearly 87 percent of the vote.Achieving this transformation, however, requires a huge increase in electricity generation—power that is non-existent in villages like Bembou Silaty and unreliable even in the capital, Conakry. Guinea is working with neighboring Senegal on a solution: Using Senegalese gas to generate enough electricity to process its bauxite on African soil.The Global Trail of Bauxite and MigrationThe story of Guinea's bauxite extends far beyond its borders. More than 3,000km away, in Parets del Valles, Spain, the journey's end plays out. For Spain, Europe's largest consumer of Guinean bauxite, more than 90 percent of its imports come from Guinea.The aluminium produced there feeds the automotive industry and serves both industrial and domestic purposes. In Spain, there is light, hot water, paved roads—all the base elements of a decent life that remain elusive in many parts of Guinea.Increasingly, more boats are leaving directly from Guinea, towards the Canary Islands and on to mainland Europe. According to Frontex, the European Union border security agency, more Guineans arrived in the Canary Islands, Spain, in 2023 (2,324) than in the previous 13 years combined. In 2024 and 2025 combined, another 6,000 Guineans arrived.Many left, following the bauxite trail, hoping to find something more in the places where their resources are both enjoyed and exploited. "If you compare the bauxite we export with what we get in return, the difference is enormous," Aliou reflects. "We gain almost nothing. Just enough to survive."

The Arsenal Bus Parade Incident About 75 people had to be rescued from height and 16 people were arrested during Arsenal’s victory bus parade on Sunday, emergency services said. Details of the Incidents The Metropolitan police said 16 arrests had been made in the area around the parade as of 9pm on Sunday. The force said arrests had been made on charges including drunk and disorderly behaviour, drug offences, sexual assault, and assaulting emergency workers. Officers were called to the scene of a stabbing on Hornsey Road just after 8.30pm and responded with paramedics and the air ambulance. Rescue and Fire Response The London fire brigade (LFB) said it rescued “approximately 75 people” from incidents at height during the event and encouraged fans to refrain from climbing on to rooftops. It also said they attended a fire at a hotel, believed to have been caused by a stray flare. Police Response and Safety Measures Officers have been granted additional stop and search powers responding to incidents in north London around the Arsenal parade. The force said on X that a “Section 60” of the Criminal Justice and Public Order Act 1994 had been authorised overnight for police in north London. Aftermath and Warnings The LFB assistant commissioner Pat Goulbourne said: “Fortunately, the fire caused only a small amount of damage to the exterior of the building. Pyrotechnics are also believed to have triggered the fire alarms at several other locations in the area. As supporters head home, we would urge them to avoid using pyrotechnics, particularly at stations, and to keep them away from buildings and other flammable materials.”

The Death of a Prominent Indigenous ActivistBrooklyn Rivera, an Indigenous leader, politician and activist, has died at age 73 after years in Nicaraguan state custody, prompting outcry from rights advocates. Nicaragua's government attributed his cause of death to a bacterial infection that took hold after a bout of COVID-19, but critics have expressed scepticism and outrage, as the announcement came after growing pressure to ascertain his welfare.Controversial Circumstances of CustodySince September 2023, Rivera has been held in state detention, without contact with the outside world. Until recently, there had been no confirmation of his imprisonment, and his family was barred from seeing him. On Wednesday, the Ministry of the Interior confirmed Rivera's detention and published photos of the Indigenous leader intubated in a hospital, describing his condition as "delicate".International CondemnationThe United States "demanded his unconditional release" in a statement posted to social media, blaming Nicaragua's leaders for "their singular role in his cruel treatment". The United Nations Group of Human Rights Experts on Nicaragua also condemned the circumstances, with member Reed Brody stating, "If he is dead, it cannot be said that the cause was illness... The cause would be that he was in government custody in conditions of enforced disappearance for over two years, denied independent medical oversight."Rivera's Legacy and ActivismA member of the Miskito Indigenous group, Rivera has advocated for the protection of his people's ancestral lands along Nicaragua's northeast coast, which has faced pressure from government and business interests seeking to exploit its rich deposits of gold, silver and other resources. Rivera was also involved in the fight against the country's first Sandinista government from 1979 to 1990, as the leader of the Misurasata armed group.Ortega's Crackdown on DissentNicaragua's government – led by spouses Daniel Ortega and Rosario Murillo, who serve as co-presidents – has long been criticised for its hardline rule and record of human rights abuses. Under Ortega and Murillo, dissidents have faced arrest, imprisonment, torture, exile and the revocation of their citizenship. Rivera was among the leaders who spoke out against Ortega's left-wing Sandinista government.Future Implications for Indigenous RightsRivera's death comes amid growing international scrutiny of Nicaragua's human rights record. His case highlights the ongoing struggle for Indigenous rights in Central America and the risks faced by activists who challenge government policies. The international community continues to pressure Nicaragua to release all political prisoners and respect human rights standards.

Executive Summary of the Suppression AllegationsLast week the New York Times and Washington Post disclosed that the FDA directed the withdrawal of two Covid‑19 vaccine safety studies and blocked a Shingrix safety abstract, despite peer‑review acceptance. The actions raise serious questions about political interference in vaccine safety surveillance.FDA Withdraws Peer‑Reviewed Vaccine Safety StudiesIn October, FDA scientists were instructed to pull two manuscripts that had been accepted by the journals Drug Safety and Vaccine. A February decision prevented the submission of Shingrix safety abstracts to a major drug‑safety conference. The agency commissioned the work, received the findings, but has not released them.Scale of the Suppressed Studies and Their FindingsStudy 1 examined 7.5 million Medicare beneficiaries for 14 pre‑specified adverse outcomes after 2023‑2024 Covid‑19 vaccination, using a self‑controlled case‑series design with up to 90 days follow‑up. Only anaphylaxis (~1 per million Pfizer‑BioNTech doses) rose above statistical noise.Study 2 analyzed 4.2 million recipients aged 6 months to 64 years, confirming rare febrile‑seizure and myocarditis signals already on product labels.The Shingrix analysis, covering millions, reaffirmed a low but elevated Guillain‑Barré risk noted on the vaccine’s package insert.Implications for Public‑Health Transparency Ahead of the World CupThe timing coincides with the 2026 FIFA World Cup across 11 U.S. host cities, a period when measles cases have surged to >9,000 in Mexico and Canada lost measles‑elimination status. The CDC has lost roughly a quarter of its workforce in the past year and has faced editorial pressure on its weekly reports. Suppressing reassuring safety data while allowing unsubstantiated adverse‑event claims to circulate undermines clinician confidence and public‑health surveillance.Future Outlook for Vaccine Surveillance and PolicyIf political appointees continue to block peer‑reviewed findings, the credibility of federal vaccine monitoring could erode, prompting calls for independent oversight or legislative action. Transparency of the existing data may become a focal point for lawmakers and health‑care professionals as the World Cup progresses and respiratory clusters emerge.

The Breakthrough in Breast Cancer TreatmentA landmark international study has revealed that millions of women with breast cancer could safely skip chemotherapy thanks to a genomic test that determines who needs the treatment and who doesn't. The randomised trial specifically examined whether the test could identify patients who would not benefit from chemotherapy, allowing them to avoid the potentially debilitating treatment without compromising their outcomes.The Scientific Evidence Behind the TestThe results of the Optima trial, which will be presented at the American Society of Clinical Oncology's annual meeting, are being hailed by experts as gamechanging. The five-year cancer-free survival rate was 93.7% in the group that skipped chemotherapy, which was statistically non-inferior to the 94.9% rate in patients randomly assigned to receive chemotherapy.The Prosigna genomic test analyzes the activity of 50 specific genes in tumor tissue to determine the molecular subtype and develops a risk of recurrence score to help doctors decide if chemotherapy is necessary. This precision medicine approach allows for personalized treatment decisions based on the unique characteristics of each patient's cancer.A Patient's Journey to Avoiding ChemotherapyKaren Bonham, a speech and language therapist from Swansea in Wales, was one of 4,429 patients with breast cancer recruited to the trial from countries including the UK, Norway, Sweden, Australia, New Zealand and Thailand. Diagnosed with cancer in 2017 at the age of 55 after routine breast screening, Bonham described the news as shocking."It certainly propels you into a world of uncertainty. Life priorities realign – you simply want to survive," she said. Dreading chemotherapy, she agreed to join the Optima trial after undergoing surgery. She was only days away from starting treatment and had already cut her hair short when the results came back in September 2017.While taking a walk on a Welsh beach, Bonham received a phone call from her hospital informing her she had been allocated to the group of patients that would not be having chemotherapy. "How to describe the initial feeling? Immense relief? Like Christmas? Certainly a mixture of the two," she said.The Future of Personalized Cancer CareToday, Bonham, now 64, retired and living in Cardiff, is free of cancer, healthy and shows no signs of the disease coming back. "It is coming up to nine years since my diagnosis," she said. "I am mindful of my diagnosis, alert to potential changes in my body but do not feel defined by [it]. I walk, enjoy yoga and live well."While not every woman with breast cancer will be able to skip chemotherapy—the treatment remains necessary and important for many—the trial results suggest that genomic testing can safely identify those who can avoid it. This approach represents a significant shift toward personalized medicine in oncology, reducing unnecessary treatment and its associated side effects while maintaining excellent outcomes."I hope that the trial will bring positive patient outcomes to many," Bonham said, reflecting on the potential impact of this research on future breast cancer patients.