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The UK medicines regulator has opened an inquiry into a growing number of clinics that sell injectable peptides while promoting them as cures for everything from ageing to injury recovery. The investigation, disclosed by the Guardian, focuses on whether these businesses are breaching the Human Medicines Regulations 2012 by making unauthorised medicinal claims. Interest in peptide‑based treatments has surged in recent years, driven by social‑media influencers, some healthcare professionals, and direct‑to‑consumer marketers. Yet the scientific foundation for most of these claims is weak, with the bulk of research confined to animal models or cell‑culture studies. According to an MHRA spokesperson, any clinic that advertises a peptide as having therapeutic benefits must treat the product as a medicine, which triggers a comprehensive regulatory framework. "If clinics offering peptide injections make medicinal claims for those treatments, the products will be considered medicines and subject to regulation," the agency warned, adding that it will act against any identified breaches. Guardian reporters identified several high‑ranking Google search results that list peptides such as Cortexin (promoted for neuroprotection), BPC‑157 (claimed to aid tissue repair), and Thymosin Alpha (advertised to boost immunity). After being contacted, one clinic removed the statements from its website. Another clinic, while acknowledging the limited human evidence, continued to market seven specific peptides, providing price lists (£350 per month for a single peptide, £450 for two) and offering delivery via vials, syringes, or pre‑filled pens for an additional fee. During a free consultation, a clinician highlighted the experimental nature of the products, noting the absence of large‑scale, randomised clinical trials and recommending a break of four to eight weeks between treatment cycles to mitigate unknown risks. The clinician suggested BPC‑157 for post‑exercise recovery, describing it as a facilitator of cellular repair and blood flow, but warned against its use in smokers or individuals with a family history of cancer due to potential angiogenic effects. The second peptide discussed was MOTS‑C, portrayed as a mitochondrial enhancer that could improve stress resilience, lower insulin resistance, and reduce visceral fat by boosting cellular energy production (ATP). The MHRA confirmed it is reviewing whether the clinician’s statements constitute medicinal claims. The clinic defended its approach, emphasizing that it clearly informs clients that the peptides are not licensed medicines and that the evidence base is largely pre‑clinical. In a broader statement, Lynda Scammell, head of borderline products at the MHRA, explained that peptide products may be marketed as cosmetics, supplements, or medicines, and each case is assessed on its intended use, pharmacological effect, and supporting evidence. She added, "We disregard claims that products are for ‘research purposes’ if it is clear that such claims are being used as an attempt to avoid medicines regulations." Peptides are short chains of amino acids, some of which occur naturally (e.g., insulin). While synthetic peptide analogues like semaglutide and tirzepatide have secured approval for weight‑loss treatments, many of the compounds promoted by these clinics remain experimental and lack the rigorous safety and efficacy testing required for medicinal products.

Les Kiss is set to take over the Wallabies in July, inheriting a side desperate to climb back to the top of world rugby. He faces a tight schedule – 14 months and 19 Tests – before the 2027 Rugby World Cup that Australia will host. Describing his mandate, Kiss stresses that he is not aiming for a radical overhaul. "It's not a revolution, it's evolution," he told the Guardian. "Core values like discipline, accountability and strategic planning stay firmly in place." What makes Kiss an outlier is his background: a former rugby league international who never played union at senior level. He says this forced him to "earn his stripes" in the union code, learning that culture and standards in the locker room drive performance on the field. His personal story is rooted in a family that escaped the Hungarian Revolution and settled in Bundaberg, and a playing career that saw him sprint down the wing before a knee injury sidelined him for four years. Those experiences, he believes, forged the resilience he now brings to coaching. After a stint in marketing and junior coaching, Kiss transitioned to union coaching, first as a defence coach for the Springboks (2001‑02), then as an assistant with Ireland (2009‑15), director of Ulster Rugby, and finally a three‑year spell with London Irish in the Premiership. Returning to Australia in 2024 to lead the Queensland Reds, he guided the franchise to its most prolific try‑scoring season in three decades, back‑to‑back quarter‑final appearances and record crowd numbers. The Reds sit 4‑2 in the 2026 Super Rugby Pacific season and are eyeing a top‑four finish. Kiss’s coaching philosophy centres on connection. "Coaching is about rapport and building something strong together," he says, adding that he is fully invested and treats every team like family. His transition to the Wallabies will be smoothed by a close partnership with current head coach Joe Schmidt. The two have shared roughly 40 Tests, developing a strong rapport that Kiss believes will help him "understand the breakdown" and set the right structures for success. The emerging "Kiss army" already includes former All Blacks staffer Scott McLeod as defence coach, analyst Eoin Toolan, set‑piece specialist Tom Donnelly, scrum guru Mike Cron, and consultant Laurie Fisher. Skills coach Mick Byrne and U20s boss Chris Whitaker also remain on board. While his new responsibilities grow, Kiss assures fans he remains 100% committed to the Reds, vowing not to let the franchise down despite his expanding duties. On the player front, Kiss highlights a blend of seasoned talent and fresh faces that could power Australia’s World Cup campaign. The likes of Mark Nawaqanitawase, Max Jorgensen, former winger Dylan Pietsch, and NRL convert Zac Lomax are poised to add dynamism, while 18‑year‑old prodigy Treyvan Pritachard offers a glimpse of the future. Ultimately, Kiss believes the Wallabies embody a uniquely Australian style – inventive, physical, and expressive – forged in backyard games and a culture of resilience. "The Australian way isn’t formulaic; it’s about solving problems on the field in our own special way," he concludes.

A stunning visual recap of the week's top stories, curated by photographer Jim Powell, has been published by The Guardian. The selection of images provides a glimpse into global events and everyday life across various countries.The photographs, presented in a gallery format, highlight significant moments that have shaped the week. While specific details about each image are not provided, the collection offers a unique perspective on international news and culture.Published by The Guardian on April 3, 2026, this visual series is a testament to the power of photography in storytelling and global connectivity.

US senators have strongly rebuked Ticketmaster for increasing ticket fees following a regulatory crackdown on hidden charges. This move has been described as a 'bait and switch' tactic, leaving consumers with higher costs.The Federal Trade Commission (FTC) had mandated Ticketmaster to disclose all concert ticket fees upfront, known as all-in pricing, starting last May. In response, the company removed the order processing fee charged at the end of a transaction. However, documents obtained by the Guardian reveal that Ticketmaster simply raised other fees to offset the loss, potentially violating the FTC's ban on misleading fees.Senator Richard Blumenthal from Connecticut expressed his concerns, stating, 'Ticketmaster seems to believe it has a get-out-of-jail-free card to ignore antitrust and consumer protection laws. The FTC is going to have to choose whether to protect consumers and enforce the law, or cave to Ticketmaster lobbyists.'The FTC had sued Ticketmaster and its parent company, Live Nation Entertainment, last September for hiding mandatory fees until the end of the transaction. Ticketmaster claims it complies with the FTC's all-in pricing rules.In response to the criticism, Ticketmaster stated, 'Since May 2025, tickets on Ticketmaster.com have displayed the full price upfront in line with the FTC's all-in pricing rule. We also provide explanations of fees during the purchase process and maintain a dedicated page with additional information.'Senator Elizabeth Warren from Massachusetts also criticized Ticketmaster, saying, 'Too many giant monopolies think the law doesn’t apply to them, and it’s American families who are forced to pay the price.'An ongoing federal trial is examining whether Ticketmaster operates an illegal monopoly in the live music industry. The company denies these allegations.

Friko, the Chicago‑based indie outfit, is gearing up for the launch of their second LP, Something Worth Waiting For, slated for 24 April. The record, described as a “radiant ramble” through modern indie rock, reflects the band’s recent touring experiences and explores themes of yearning, growth, and stability.The lead single, "Choo Choo", bursts with a road‑trip vibe, pairing vocalist‑guitarist Niko Kapetan’s urgent, quavering delivery with guitarist Korgan Robb’s atmospheric riffs. Critics note a vocal timbre reminiscent of Modest Mouse’s Isaac Brock and Sparks’ Russell Mael, while the track’s lyrical nods to classic American road food add a playful, homespun charm.Since their 2024 debut Where We’ve Been, Where We Go From Here, Friko has expanded from a duo (Kapetan and drummer Bailey Minzenberger) to a full four‑piece, adding Robb and touring bassist David Fuller. The new album also benefits from the touch of Grammy‑winning producer John Congleton, known for work with Mannequin Pussy, The Mountain Goats, and St Vincent. His influence shines on the Bowie‑esque chamber‑pop ballad "Seven Degrees", underscoring the group’s evolving sound.In addition to the album news, the Guardian’s weekly Add to Playlist roundup spotlights a curated selection of fresh tracks. Highlights include Wallis’s techno‑laden “Biscuit,” Beth Orton’s intense “The Ground Above,” Toronto pop‑star Chxrry’s catchy “Hall of Fame,” and a collaborative anti‑immigrant‑detention compilation track by Wendy Eisenberg’s trio Darlin’. The list also features Jeff Parker’s hopeful “Like Swimwear (Part One)”, a dubstep‑rap hybrid “Duro” from Skrillex and Young Miko, and Cass McCombs’s garage‑rock anthem “Seeing the Elephant”.Listeners can stream the full playlist on Spotify, Apple Music, Tidal, or other services, ensuring the week’s most inventive indie and electronic releases are just a click away.

The Guardian’s investigation has revealed that the company responsible for the unauthorised partial felling of a 500‑year‑old oak in Whitewebbs Park, Enfield, was Ground Control, a maintenance business that reports a turnover of £190 million. The tree was cut down in September 2025 on behalf of Mitchells & Butler Retail (MBR), the owner of the Toby Carvery restaurant chain. MBR initially defended the action, claiming its contractor warned that the oak was diseased and posed a safety risk. However, a coalition of experts – including a Forest Commission investigator and ancient‑tree specialist Russell Miller – found the tree to be healthy with no imminent danger. Miller described the alleged “hazard” as an old, semi‑occluded wound that did not justify felling the entire tree. According to Dr. Ed Pyne of the Woodland Trust, the delay in identifying the contractor highlights a broader lack of transparency: "What evidence exists that the tree was dangerous? What qualifications did the operatives have?" He added that the justification for the removal remains unsubstantiated. Ground Control’s own documentation shows the work was assigned to its grounds‑maintenance team rather than its specialist arborists, a detail that fuels further criticism of MBR’s decision‑making process. Sources close to the firm say an internal review was conducted by a contracts manager, not a tree expert. Enfield Council, which owns the park, has launched legal action to evict Toby Carvery after MBR refused to apologise or offer compensation. The council also referred the incident to the police, but officers declined to investigate, deeming it a civil matter. Complicating the dispute, MBR is majority‑owned by investment group Enic, which holds strong financial ties to Tottenham Hotspur. The football club plans to develop a women’s training academy on 17 hectares adjacent to the park, a proposal opposed by the local campaign group Guardians of Whitewebbs. The group has secured a judicial review of the planning permission, set for June. In a statement last April, MBR asserted that its “specialist arboriculture contractors” deemed the split and dead wood a serious health‑and‑safety risk. A Toby Carvery spokesperson declined further comment, citing ongoing legal proceedings. The revelation of Ground Control’s involvement adds a new layer to the controversy, raising questions about corporate responsibility, environmental stewardship, and the adequacy of legal protections for historic trees in urban green spaces.

The increasing congestion of Earth's orbit with satellites is raising concerns about the environmental impact of space activities. A recent UN report highlighted the urgent need for sustainable practices to manage potential orbital congestion and environmental impacts.One of the most pressing issues is the risk of space debris, also known as 'space junk', which includes discarded rocket stages and defunct satellites. The surge in orbital activity has created a significant collision risk, and there have already been a handful of crashes. In 2007, a Chinese anti-satellite weapon test intentionally blew up a weather satellite, creating a dangerous cloud of space debris.Researchers fear that the impact of space activities on the ozone layer, which shields the planet from radiation, could be significant. A study found that roughly 10% of particles in the stratosphere contain metals that originated from space activities such as rocket launches.The Guardian has launched an interactive project to visualize the tens of thousands of human-made objects spinning around the globe. The project reveals a significant problem which, if left unchecked, could disrupt some of humanity's most important services such as the internet and weather prediction.As a global society, we rely on satellites constantly, not only to help us navigate around using Google Maps, but also to provide internet access and, critically, predict the weather. Space-based monitoring of the Earth also allows researchers to track deforestation, desertification, glacier and ice-cap melt, and the spread of oil spills.

The Easter bunny has been a staple in many films, often depicted as cute and harmless, but sometimes also menacing and deadly. The Guardian has ranked Easter bunny movies, providing a list of 20 films that showcase the versatility of the Easter bunny character. The list includes Who Framed Roger Rabbit (1988) at number one, a film that combines live-action and animation, featuring a character with characteristics of many cartoon critters. Other notable mentions include Wallace & Gromit: The Curse of the Were-Rabbit (2005) at number three, a stop-motion animated film by Aardman, and Watership Down (1978) at number two, an animated adaptation of Richard Adams's novel. The list also features films like Monty Python and the Holy Grail (1975), which includes a scene with the holy hand grenade of Antioch, and Donnie Darko (2001), which features a sinister figure in a metal-faced bunny suit. Other films, such as No Surrender (1985), Fatal Attraction (1987), and The Favourite (2018), also make the list. The ranking showcases a wide range of Easter bunny depictions, from cute and harmless to menacing and deadly, demonstrating the versatility of the character in cinema.

A US court has dismissed a lawsuit from WhatsApp's former security chief, who alleged that parent company Meta ignored internal flaws he flagged about the messaging app's digital defenses.Abdullah Baig, who claims he was fired in retaliation for raising these concerns, had alleged that billions of users had been put at risk because of these vulnerabilities. Thousands of employees could view sensitive user data, including profile photos and location, Baig claimed in the lawsuit filed in September. A judge ruled he had not presented enough evidence to move forward.The US district court in northern California ruled last month to dismiss Baig's claims, with the judge, Laurel Beeler, writing on 19 March that 'the complaint does not contain sufficient facts to show that the plaintiff reported violations of SEC rules or regulations.'Baig was head of WhatsApp's security division from 2021 to 2025. He said he had expressed concerns about cybersecurity issues to his supervisor five times but was ignored; he also said he wrote directly to Meta's CEO, Mark Zuckerberg, about what he saw as a violation of US Securities and Exchange Commission rules and escalating retaliation against him. He also claimed that the company didn't fix the hacking of more than 100,000 accounts daily – and focused instead on user growth. At the time, WhatsApp said in a statement that he was 'a former employee dismissed for poor performance' who had filed a suit based on distorted claims.A WhatsApp spokesperson said: 'This ruling reaffirms what we've said all along: These claims have no merit. We're proud of our strong record of protecting people's privacy and security, and will continue building on it.'Baig's lawyer suggested in a statement emailed to the Guardian that the legal fight was not over. 'Mr Baig is not done fighting for users,' said Wilmer Harris, who represents Baig. 'The judge dismissed on pleading grounds, not merit, and we look forward to addressing those deficiencies and ensuring Meta has to finally engage with the substance of Mr Baig's allegations.'