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President Donald Trump has announced a new policy threatening to impose 100% tariffs on US pharmaceutical companies that do not agree to lower their drug prices. This move is part of his effort to address the high cost of prescription medications in the US.The tariffs will specifically target branded drugs and their active ingredients, while generic drugs, which account for over 90% of medicines sold in the US, will be exempt for at least one year. Additionally, certain specialty drugs, such as orphan, veterinary, and other specialty drugs, will be exempt if they are from countries with which the US has a trade deal or meet urgent public health needs.Drugmakers that enter into pricing agreements with the White House and onshore drug production will be exempt from the tariffs. Companies planning to increase their domestic manufacturing will face a 20% tariff that will escalate to 100% over four years.The policy has been met with criticism from industry groups, such as the Midsized Biotech Alliance of America (MBAA), which argues that it creates an "unfair two-tiered system" that benefits large companies with diversified portfolios.Trump has been under pressure to lower drug prices, with US patients often paying nearly triple what patients pay in other developed nations. The announcement comes as the White House faces pressure from consumers to address rising costs amid other tariff-related price increases and high gas prices triggered by geopolitical tensions.

The UK’s chancellor, Rachel Reeves, is set to sit down with the chief executives of Sainsbury’s, Tesco and Morrisons on Wednesday. The meeting aims to gauge the scale of possible price hikes and shortages of essential household goods as the nation grapples with a sharp rise in energy, fuel and fertiliser costs triggered by the ongoing Middle East conflict. A Treasury source described the gathering as a "fact‑finding, open discussion" intended to identify any supply squeezes and to forecast the impact on the cost of living over the coming months. Allan Leighton, executive chair of Asda, will not attend but has publicly urged the government to "stand up and start doing stuff" to aid farmers and curb fuel prices, warning that food costs will inevitably climb if the conflict persists. Simon Roberts, chief executive of Sainsbury’s, cautioned that price increases are "unlikely to rise until the summer" thanks to long‑term contracts on energy and fertiliser that currently keep a lid on costs. Nevertheless, UK growers are sounding the alarm. Producers of tomatoes, cucumbers, peppers and aubergines say higher input costs could force them to pull plants from the ground, creating potential gaps on supermarket shelves. Lee Stiles, secretary of the Lea Valley Growers’ Association – the region often dubbed London’s "salad bowl" – is lobbying for indoor food producers to be classified as "energy‑intensive users" alongside steel, chemicals, cement and glass, thereby qualifying for additional support with surging energy bills. Stiles also called on retailers to renegotiate contracts with growers to reflect the cost surge since the Middle East conflict began. He warned that the upcoming increase in standing charges on 1 April – a fixed daily fee for accessing the gas and electricity network – will further strain producers’ margins. "Growers have already invested in plants and labour for three to four months," Stiles said. "When you do the maths, the numbers don’t add up. They would lose less money by sending workers home, pulling the plants out and turning off the boiler." If domestic growers cut the season short, European glasshouses, which normally supply the UK’s salad market at this time of year, may struggle to fill the void, risking a repeat of the fresh‑produce shortages experienced in early 2023. The British Poultry Council (BPC) echoed these concerns, highlighting pressures on supplies of oil, gas, fertiliser and essential feed components. "These factors are creating sustained upward pressure on the cost of poultry production," the BPC warned, adding that while some cost increases may be absorbed, others will inevitably be passed on to consumers. Richard Griffiths, BPC chief executive, noted that while many farmers have long‑term energy deals, costs such as diesel are rising rapidly, and there are fears that vital medicines could become unavailable at any price. In response, the government has announced a £117 cut to household energy bills, an increase to the legal minimum wage, and the launch of a £1 billion "crisis and resilience" fund aimed at helping vulnerable households with expenses such as heating oil.

Coordinated strikes by United States and Israeli forces hit Tehran, Isfahan and several other Iranian cities on Tuesday, prompting widespread power outages and extensive damage to civilian sites. The Ministry of Energy confirmed that shrapnel from the raids ruptured a primary power‑transfer line, but the outage was restored within a few hours. Among the most critical targets was the Tofigh Darou pharmaceutical complex in the Karaj industrial zone. The facility, which supplies over 90% of Iran’s domestically produced medicines—including cancer and multiple‑sclerosis treatments—sustained heavy damage from multiple projectiles. In central Iran, Isfahan endured a barrage of heavy bunker‑buster bombs over a nearby mountainous area, likely aimed at military installations. The explosions triggered secondary blasts that illuminated the night sky and produced reverberating shockwaves across the city. North‑west of Tehran, in Zanjan, a building identified as the administrative department of the Hosseinieh Azam religious centre was struck, resulting in at least four fatalities and several injuries. Iranian authorities now claim that more than 2,000 people have been killed by US‑Israeli attacks since the conflict erupted on 28 February, with residential blocks, schools, hospitals and historic sites also affected. Additional targets this week included civilian nuclear facilities, major steel producers, petrochemical plants, and the Iran University of Science and Technology, where an imaging satellite was developed. A professor linked to Iran’s missile programme and his two children were assassinated at their home in northern Tehran. U.S. President Donald Trump reiterated threats to strike Iran’s oil and gas infrastructure, power plants and water‑desalination facilities. Despite the onslaught, the Islamic Revolutionary Guard Corps (IRGC) continues to project defiance. A spokesperson for the Khatam al‑Anbiya Central Headquarters declared that Tehran’s adversaries are “humiliated and on the path of destruction,” while senior commander Ali Fadavi warned that American warships are vulnerable and allegedly transmit false transponder signals. The IRGC also released footage of ballistic missiles aimed at Israel and surrounding nations, and claimed to have downed two U.S. MQ‑9 Reaper drones, promising retaliatory strikes against technology firms linked to the United States and Israel. Domestically, the judiciary announced the execution of two members of the foreign‑based Mojahedin‑e‑Khalq (MEK) group, labeling them terrorists. This follows a series of recent executions tied to the January protests and broader dissent. Authorities also issued new indictments against roughly 200 individuals accused of assisting the U.S. and Israel, including alleged “mercenaries” who disseminated strike footage abroad. Penalties for national‑security offenses now encompass asset confiscation and capital punishment. President Masoud Pezeshkian convened his first cabinet meeting since the war’s onset in a makeshift, blue‑covered space, emphasizing that any peace negotiations will safeguard Iran’s “dignity, security and national interests.” Israel’s Channel 14 reported that Pezeshkian sought greater negotiating leverage with the United States, a request allegedly rebuffed by IRGC chief Ahmad Vahidi.

Israeli and U.S. forces launched a series of air strikes on Tuesday that struck Tofigh Daru Research and Engineering Company, one of Tehran’s largest producers of anaesthetics and anti‑cancer medicines. The state‑run firm, owned by the Social Security Investment Company, saw its drug‑production line damaged, according to an official post on X. In the north‑western city of Zanjan, a separate strike hit the Husseiniya Azam, a Shia congregation hall adjacent to a mosque. Iranian Red Crescent teams rescued two people from the rubble; one of the victims died and several others were injured. Further attacks were reported in the western province of Kermanshah, where a civilian contracting company in Qasr‑e Shirin – a border town with Iraq – was hit. One person was killed and eight injured, the Mehr news agency said. Heavy bombing was also confirmed in Isfahan, a strategic hub for Iran’s defence industry and home to key nuclear facilities such as Natanz. Local officials indicated that the strikes may have targeted “military sites,” though the exact locations and damage assessments remain unclear. Iranian officials condemned the operations. Former foreign minister Javad Zarif denounced the targeting of the pharmaceutical plant as a deliberate attack on a medical facility, calling the aggressors “desperate” and accusing them of “diabolical delusions.” Governor‑level security official Akbar Salehi echoed these concerns, noting that the strikes appeared aimed at military installations without specifying which ones. The broader conflict has already claimed 1,937 Iranian lives since the joint U.S.–Israeli campaign began on 28 February, while 20 Israelis have been killed. Recent Israeli interceptions using the Iron Dome and David’s Sling systems have limited damage on Israeli soil, but impact sites were reported in Tel Aviv, Bnei Brak and Petah Tikva. Amid the escalating violence, diplomatic channels remain active. U.S. Secretary of State Marco Rubio told Al Jazeera that communications between Washington and Tehran continue, primarily through intermediaries, and that the U.S. aims to achieve its war objectives “in weeks, not months.” Pentagon chief Pete Hegseth added that negotiations to end the conflict are “very real, ongoing and gaining strength.” Iran’s Islamic Revolutionary Guard Corps (IRGC) claimed a retaliatory strike, saying it hit an Israeli container ship in the Gulf with a ballistic missile and that Iranian drones targeted a group of U.S. Marines near a UAE military base. Public sentiment in Iran has turned sharply hostile, with pro‑state demonstrations erupting in Tehran as citizens protest the continued air raids. The atmosphere, described by Al Jazeera’s Tohid Asadi as a “cloud of mistrust,” reflects growing frustration over diplomatic dead‑ends and the relentless cycle of attacks.

In a recent editorial, the Guardian highlighted the danger of Israel applying the same brutal tactics used in Gaza to Lebanon, and Medical Aid for Palestinians echoes that warning.Field reports from Lebanon describe a climate of terror fueled by mass forced‑displacement orders and relentless military strikes, including assaults on healthcare workers. Aid groups are scrambling to assist Palestinian refugees who have fled their homes, while many others remain trapped, deepening panic in already overcrowded camps plagued by poverty and scarce services.The Israeli military appears to be mirroring Gaza’s playbook: terrorising civilians, imposing forced displacement, and targeting humanitarian and medical infrastructure. Despite a declared cease‑fire in Gaza, Israeli attacks have killed more than 690 Palestinians since October, and restrictions on aid are creating lethal shortages of medicines and equipment.Meanwhile, the West Bank endures escalating settler violence and an Israeli annexation agenda that now threatens to extend into Lebanon, further destabilising the region.Medical Aid for Palestinians stresses that impunity for attacks on civilians and health services endangers both the populations they serve and the organisation’s staff across Gaza, the occupied West Bank and Lebanon.According to the statement, the UK government must not cherry‑pick when to uphold international law. It calls for decisive action to hold all perpetrators accountable, warning that inaction will lead to catastrophic human costs. The world, it asserts, cannot allow the horrors witnessed in Gaza to be replayed in Lebanon, and governments should not become complicit allies of such atrocities.

The UK's National Health Service (NHS) is facing potential medicine shortages due to supply chain disruptions, with the head of NHS England, Jim Mackey, warning that some medicines could run out in weeks or even days. Mackey cited the country's reliance on imports, with 75% of medicines coming from abroad, as a major concern.Mackey revealed that a team is in place to focus on identifying potential risks in the supply chain, and that the NHS is working to mitigate the impact of any disruptions. He stated that the NHS generally has enough medicine to last a few weeks, but that some products may only have days' worth of supply.The concerns about medicine shortages come amid the ongoing conflict in the Middle East, which has raised worries about cost implications and supply disruption. Experts have noted that pharmacies are seeing disturbing spikes in prices, which can be an early indicator of challenges.The UK government has stated that there are currently no reported medicine shortages as a result of the conflict, but that they are monitoring the situation closely and have established processes in place to manage disruption across the health and social care sector.

Eli Lilly, the US pharmaceutical group behind the Mounjaro weight-loss drug, is seeking to resume its investments in the UK after pausing them last year. The company is in talks with UK ministers to regularly increase NHS drug prices and end a rebate scheme. Patrik Jonsson, president of Eli Lilly's international business, expressed optimism about reaching an agreement this summer.The talks will also explore 'innovative' pricing plans, such as linking payments for anti-obesity drugs to whether the treatment helps patients return to work. This comes as the US pharmaceutical industry increases pressure on the UK, with Keir Starmer agreeing to the first increase in NHS cost-effectiveness thresholds in 27 years. The threshold was raised from £20,000 to £30,000 a year for every year of life gained to £25,000 to £35,000.Eli Lilly was one of several pharmaceutical companies that ditched or paused almost £25bn in planned investments in the UK last year. The company paused its plans to invest in a laboratory site in central London. Jonsson stated that the resumption of Eli Lilly's investment would depend on the outcome of its talks with the government.He emphasized that prices for medicines in the UK had been 'far too low for far too long' and that the threshold couldn't remain static for another three decades. The UK agreed to pay 25% more for new medicines by 2035 as part of a US-UK drug pricing deal, which could eventually reach £9bn a year.Large pharmaceutical companies have protested about a 'rebate' scheme, under which they are required to pay back a chunk of revenue from sales of branded medicines. This scheme is expected to fall in 2026, although Jonsson believes payments 'should actually get down to zero' over time.

The UK is on the brink of a medicine shortage crisis, with experts warning that the country is just weeks away from feeling the effects of the ongoing conflict in Iran. The war has already disrupted the supply of essential raw materials, including oil, gas, crop fertiliser, and helium.The pharmaceutical industry, which relies heavily on imports, is particularly vulnerable to these disruptions. India, known as the 'pharmacy of the world', produces a significant proportion of generic drugs and active pharmaceutical ingredients (APIs) used globally. However, with the Strait of Hormuz largely closed due to the conflict, the transportation of these vital supplies is becoming increasingly difficult.Medicine prices are also expected to rise as a result of the conflict. The US-Israel war on Iran has doubled air freight costs, which could make some medicines loss-making to supply to the NHS. While suppliers have long-term pricing agreements with NHS hospitals, they have more flexibility to increase prices for drugs supplied to GP practices and pharmacies.The UK's reliance on imported medicines is significant, with about half of its medicines produced domestically, a third coming from India, and another chunk from the EU. During the Covid pandemic, paracetamol and other painkillers were in short supply in Britain and elsewhere, as drugmakers in India struggled to keep up with demand.Medical distributors typically stock six to eight weeks of supplies to avoid shortfalls, but if the conflict drags on, drug shortages could emerge in only a few weeks' time. Experts warn that the overall ripple effect on the industry is significant, with the patient ultimately picking up the tab, either directly or via public health systems like the NHS.

The ongoing United States-Israeli conflict with Iran has triggered severe disruptions to global LNG supplies in the Gulf, creating the most significant energy market disruptions in recent years. The critical Strait of Hormuz, through which 27 percent of the world's maritime oil trade and 20 percent of LNG shipments pass, has been brought to a near standstill.In response to the conflict, oil-producing nations such as Saudi Arabia have rerouted oil through alternative pipelines, while Qatar has completely halted LNG production at its Ras Laffan and Mesaieed facilities following attacks on its energy infrastructure. This disruption comes as natural gas makes up about a quarter of global energy consumption, raising widespread concerns about the impact on nations heavily reliant on gas imports.Natural gas is formed over millions of years from decomposed organic matter subjected to intense heat and pressure beneath the Earth's surface. LNG represents natural gas that has been cooled to -162 degrees Celsius through cryogenic processing, shrinking it to a 600th of its gaseous volume. In its liquid state, LNG is colorless, odorless, and non-flammable, making it safe and efficient to transport across vast distances.Before liquefaction, the gas undergoes purification through water-based solvents and molecular sieve beds to remove impurities including carbon dioxide, hydrogen sulfide, water, and mercury. Heavier hydrocarbons are then separated from methane and ethane through fractionation. The resulting fuel is typically composed of 85 to 95 percent methane, with small amounts of ethane, propane, butane, and nitrogen.LNG is stored in large insulated tanks without requiring high-pressure infrastructure, then pumped onto double-hulled carriers for shipment to terminals worldwide. At destination facilities, LNG is heated using seawater or warm water baths until it vaporizes—a process known as regasification—before being distributed through pipelines for consumption.Once returned to a gaseous state, LNG serves multiple purposes globally. Residential applications include cooking, heating, and electricity generation, while supporting hot water systems in homes and heating for commercial buildings. In power generation, LNG offers a comparatively low-carbon alternative to coal and oil. Industrial applications span fertilizers, plastics, paints, and medicines, with LNG also used to fuel heavy-duty vehicles and ships.The disruption has particularly affected agricultural production, as Gulf nations export close to half the world's traded urea—a key fertilizer component. Natural gas serves as both the primary feedstock and fuel for fertilizer manufacturing, with the halt in production forcing producers across the region to suspend or reduce operations.While primarily valued as an energy source, LNG processing yields significant by-products with industrial and medical applications. The most notable is helium, extracted during cryogenic processing. With global helium production estimated at 180 million cubic meters annually, the disruption to Qatar's LNG facilities has removed approximately 5.2 million cubic meters from the market each month—accounting for about a third of global monthly production.Helium is critical for cooling superconducting magnets in MRI and CT scanners, with the average MRI machine requiring about 1,700 liters of liquid helium. The element is also vital to the data center industry, where it conducts heat away from silicon components, preventing damage to semiconductors. Additionally, the natural gas value chain generates petrochemical derivatives that serve as feedstock for manufactured goods, including medical-grade plastics.According to the International Gas Union's 2025 World LNG Report, 411.24 million tonnes of LNG were traded in 2024. The United States emerged as the largest exporter with 88.4 million tonnes, followed by Australia (81 million tonnes), Qatar (77.2 million tonnes), Russia (33.5 million tonnes), and Malaysia (27.7 million tonnes). Together, these top five suppliers account for more than three-quarters of global LNG supply.China was the largest importer with 78.6 million tonnes in 2024, followed by Japan (67.7 million tonnes), South Korea (47.1 million tonnes), India (26.1 million tonnes), and Taiwan (21.8 million tonnes). These top five importers constituted nearly 59 percent of all global LNG imports that year.South Asian nations face particularly severe risks from the current conflict. Pakistan, where natural gas accounts for 28 percent of electricity generation for its 250 million people, and Bangladesh, where gas supplies half of all electricity for its 176 million population, are heavily dependent on Gulf imports. Qatar and the United Arab Emirates supply approximately 99 percent of Pakistan's LNG imports and 72 percent of Bangladesh's.In response to the energy crisis, Pakistan has implemented emergency measures including a four-day workweek for government employees and extended school holidays. Bangladesh has reduced gas supplies and is seeking nearly $2 billion in international loans to fund energy inputs and maintain price stability. India, which relies on Gulf nations for about half of its LNG and generates 5 percent of its electricity from gas, has shifted toward coal usage as LNG disruptions continue.