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At least 50 new accounts on Polymarket, a prediction market platform, made substantial bets on a US-Iran ceasefire on Tuesday, resulting in profits of hundreds of thousands of dollars. These bets were placed despite escalating rhetoric from Donald Trump and few signals of an imminent deal.An analysis of blockchain data shows that one wallet, created on Tuesday at 10am ET, placed roughly $72,000 in bets at an average price of 8.8¢ and cashed out for a profit of $200,000. Another wallet, which joined the platform on April 6, won $125,500.The trading pattern of newly created accounts placing strategic, well-timed bets has raised questions about insider trading and the need for regulation in prediction markets. Bipartisan groups of senators and representatives have introduced legislation to broaden the definition of insider trading to include prediction markets.“This is why these markets need regulation,” said Todd Phillips, a professor at Georgia State University. “We can’t have people trading with inside information and expect other traders are going to be OK being in these markets.”Polymarket and other industry players, including Kalshi, have acknowledged the need to broaden the definition of insider trading on their platforms.

Iran and the United States each declared a triumph after agreeing to a two‑week ceasefire that was announced just before President Donald Trump’s deadline to force Tehran’s surrender. The conflict, which began on 28 February, has already claimed 2,076 lives in U.S.–Israel strikes on Iran and has caused thousands more deaths across the region. The fighting has also shocked global energy markets, stranding oil tankers and pushing prices to unprecedented levels. Trump announced on Truth Social that the United States would halt bombing Iran after receiving a “workable” 10‑point ceasefire proposal, adding that “almost all of the various points of past contention have been agreed to.” Iran, for its part, said it would reopen the Strait of Hormuz to commercial traffic, even as some citizens denounced the government’s perceived capitulation. Both parties are set to resume Pakistan‑mediated talks in Islamabad on Friday, though analysts warn that earlier red lines may resurface. Key terms of the Tuesday agreement: the United States will suspend air strikes for two weeks, citing that it has already achieved its military objectives and is close to a “definitive agreement concerning long‑term peace.” Iran’s foreign minister, Abbas Araghchi, pledged to halt “defensive operations” and to allow safe passage through the Strait of Hormuz, while also indicating willingness to fund reconstruction from fees collected on transiting ships. Domestic reaction in Iran remains volatile. University of Tehran professor Foad Izadi noted that the public’s pessimism stems from two prior escalations—June’s 12‑day war and the February 28 strikes—both of which occurred amid ongoing negotiations. Earlier demands: The United States had presented a 15‑point plan on 25 March, calling for a 30‑day ceasefire, immediate reopening of the Strait, Iran’s de‑commissioning of its nuclear facilities, a total ban on uranium enrichment, handover of nuclear stockpiles to the IAEA, cessation of support to regional proxies, strict limits on ballistic missiles, and a full lift of sanctions, among other items. Iran responded with a 10‑point proposal that emphasized a non‑aggression commitment from the United States, controlled passage through the Strait, acceptance of its enrichment programme, comprehensive sanctions relief, withdrawal of U.S. combat forces, compensation for war damages via shipping fees, and a binding UN Security Council resolution. Both sides have already made concessions. Iran moved from demanding a permanent ceasefire to accepting a two‑week pause, and it shifted from insisting on reparations to proposing reconstruction funding from Strait fees. The United States, meanwhile, has softened its demand for an “unconditional” Iranian surrender and has not reiterated its earlier insistence on dismantling Iran’s missile capabilities. One of the most contentious issues remains the status of Lebanon. While Pakistan’s prime minister said the ceasefire would extend to Lebanon, Israeli Prime Minister Benjamin Netanyahu denied any such inclusion, and Israel launched a major bombing campaign in Beirut shortly thereafter, killing hundreds. Looking ahead, analysts highlight that the United States is unlikely to concede on the complete withdrawal of its roughly 50,000 troops stationed across 19 Middle Eastern sites—a demand Tehran has placed on the table. The outcome of the upcoming talks will hinge on whether Washington can accommodate Tehran’s broader political and economic requests without compromising its strategic objectives.

During Donald Trump’s January 2025 inauguration, Giorgia Meloni was the only European leader invited, underscoring a brief period of close personal and diplomatic ties between Italy’s right‑wing government and the new U.S. administration. A month earlier she had been photographed sharing a private conversation with Trump at the Élysée Palace while President Emmanuel Macron celebrated the reopening of Notre‑Dame. From the outset of Trump’s second term, the Italian premier was hailed by the U.S. president as a “real live wire” and the European ally who could help “straighten out the world.” Meloni embraced the role, describing Trump as a “brilliant man” and promising to "make the West great again" together. That camaraderie has now eroded. In the wake of the US‑Israeli military action against Iran, Meloni told reporters during a Gulf‑region visit that "when we don’t agree, we must say it", explicitly rejecting the war. Her stance was reinforced a week earlier when Italy denied U.S. bombers permission to refuel at a southern base. Political analysts note that Meloni’s shift marks a decisive break from Trump’s agenda. Roberto D’Alimonte, a political‑science professor at Luiss University, warned that her earlier attempt to act as a bridge between Trump and European allies has become a “liability” she now seeks to repair. Public opinion reflects the change. Recent polls show a solid majority of Italians oppose the Iran war, and support for Trump in Italy has plunged from 35 % to just 19 %. The backlash also manifested in a recent referendum on judicial reform, where 61 % of voters aged 18‑34 rejected Meloni’s proposal—a defeat analysts link more to dissatisfaction with her foreign‑policy alignment than to the reform itself. Beyond politics, the conflict threatens Italy’s economy. As the EU’s second‑largest natural‑gas consumer—accounting for roughly 40 % of its energy mix—Italy is feeling the impact of soaring energy prices caused by the near‑total shutdown of traffic through the Strait of Hormuz. The Bank of Italy now projects only a 0.5 % growth rate for 2026‑27, down from earlier forecasts, while the national statistics office reported that Italy’s fiscal deficit has breached the EU’s 3 % ceiling, limiting fiscal flexibility ahead of next year’s elections. Despite these pressures, Meloni has not completely abandoned the United States. In March she declined Trump’s request to dispatch Italian warships to the Strait of Hormuz, aligning with other European nations, yet she stopped short of condemning the US‑led operation outright. Experts argue that Meloni’s approach is deliberately cautious. “She is pragmatic and politically skilled,” D’Alimonte said. “She will continue to balance criticism of Trump’s aggressive foreign policy with the need to preserve strategic ties, moving step‑by‑step toward a stronger European alignment without burning bridges.”

Mircea Lucescu, a Romanian football great and serial trophy winner as a player and coach, has passed away at the age of 80. Lucescu's death was confirmed by the Bucharest University Emergency Hospital, where he was admitted after reportedly suffering a heart attack on Friday morning.Lucescu was one of the most successful Romanian football coaches and players, known for being the first to qualify the Romanian national team for a European Championship in 1984. He had a lengthy coaching career spanning almost half a century, from the late 1970s to World Cup 2026 qualifying.As a player, Lucescu captained his country at the 1970 World Cup. His coaching career included stints with Shakhtar Donetsk, where he won the UEFA Cup in 2009 and accumulated 22 trophies, making him the most successful manager in the club's history.Lucescu also coached Turkish and Romanian national teams and had spells with Italian clubs such as Pisa, Brescia, Reggiana, and Inter Milan. His contributions to Romanian football have been widely praised, with Romanian President Nicusor Dan paying tribute to him as "one of the most respected figures in the history of Romanian and European football".UEFA President Aleksander Ceferin remembered Lucescu as "one of the game's true originals – a man of rare football intellect, remarkable dignity and passion". Lucescu's legacy continues to inspire generations of football players and fans.

Researchers have made a significant breakthrough in understanding why weight-loss medications, such as GLP1 receptor agonists, work better for some individuals than others. A recent study published in Nature has identified genetic variations in two genes involved in gut hormone pathways that regulate appetite and digestion. These genetic variations may help account for different weight-loss results or side-effects when taking glucagon-like peptide 1 (GLP1) medicines, which mimic natural gut hormones to regulate appetite, insulin release, and digestion. The study analyzed data from 27,885 patients on GLP1 drugs and found that specific genetic variants were associated with slightly more weight loss or side-effects like nausea and vomiting. The findings suggest that genetic differences may contribute to why people respond differently to weight-loss jabs. However, the overall impact of genetics appeared to be modest, with non-genetic factors such as sex, drug type, dose, and duration appearing to explain a substantially larger proportion of variability. The study's results reinforce that while there is substantial variability in response to GLP1 therapies, genetics is only one part of a much more complex picture. According to Marie Spreckley, an obesity expert at the University of Cambridge, the study provides plausible evidence that genetic variants could affect outcomes. However, she notes that the magnitude of these genetic effects is small in clinical terms, and that behavioral, clinical, and treatment-related factors remain the dominant drivers of outcomes. The study's authors suggest that their findings could support future efforts to use genetic information when making treatment choices for obesity. However, Spreckley cautions that the evidence is not yet sufficient to support using genetic information to guide treatment decisions in routine clinical practice.

In the spring of 2002, the modest Free Butt pub on Brighton’s seafront buzzed with a restless energy. Future stars such as Natasha Khan, then a university art student, danced atop the bar while the Yeah Yeah Yeahs thundered through their first UK dates. Behind the scenes, band frontmen like Guy McKnight of Eighties Matchbox B‑Line Disaster served pints, and budding engineers like Steve Ansell of Cat on Form fine‑tuned the sound. The atmosphere felt like a rite of passage, where any performer could slip from a cramped stage to national attention.Unlike the neatly branded scenes of New York’s garage‑rock revival or London’s Libertines‑driven hype, Brighton’s early‑2000s scene resisted a single aesthetic. Rock groups emerged from rehearsal rooms and tiny clubs with wildly different looks and sounds, creating a cultural mosaic rather than a monolithic movement.Electrelane’s guitarist recalls recording their debut Rock It to the Moon in a studio once owned by the Levellers, and crafting their sophomore effort inside a former public toilet. These unconventional spaces proved surprisingly fertile, underscoring the city’s DIY spirit.By the turn of the millennium, the big‑beat dominance of Fatboy Slim and Skint Records had faded, making way for a grassroots rock surge. Sea Power relocated from Reading to Brighton, drawn by the city’s “dilapidated charm and fresh sea air”. Their self‑organized Club Sea Power nights at the Lift offered a chaotic yet liberating platform that eventually caught Rough Trade’s attention.Women played a pivotal role in shaping the scene’s infrastructure. Promoters Lisa Lout and Anna Moulson, both still active, booked seminal shows—including the Strokes’ first UK gig at the Lift in 2001—and helped launch the Great Escape festival. Their efforts ensured that bands such as the Pipettes, Electrelane and Bat for Lashes could share stages and media coverage.Artists recall the city’s palpable sense of belonging. Rose Dougall of the Pipettes describes a landscape where “alternative culture was on every street, from vintage shops to the colour of the houses,” and where “small venues made it feel attainable to launch a project.” Similarly, Brakes frontman Eamon Hamilton contrasts Brighton’s walk‑able, collaborative vibe with London’s darker, more competitive energy.Music journalism mirrored the scene’s intensity. Everett True and photographer Steve Gullick launched Careless Talk Costs Lives in 2002, a deliberately short‑run magazine that championed female writers and bands at a time when the industry was still heavily male‑dominated.As rents surged through the 2010s, many of the cheap flats, rehearsal rooms and iconic venues that underpinned the scene vanished. The Free Butt closed, independent record stores shuttered, and the once‑abundant low‑cost infrastructure dwindled, prompting a migration of creative energy down the coast to places like Margate, Ramsgate, Folkestone and Shoreham.Nevertheless, the remnants of Brighton’s network continue to nurture new talent, from the Kooks to Dream Wife and Gazelle Twin. The city’s strength lies not in a singular sound but in its capacity to host a “constant collision of wildly dissimilar bands,” allowing artists to develop authentically and fearlessly.

Emma Sing, a 25‑year‑old Rugby World Cup winner and multiple Six Nations grand‑slam champion, says she is aiming to secure the England full‑back jersey for the upcoming Women’s Six Nations. Despite her impressive résumé – three Premiership Women’s Rugby titles with Gloucester‑Hartpury, 13 England caps since 2022 and three appearances at the 2025 World Cup – Sing insists there is no personal rivalry with fellow full‑back Ellie Kildunne, the Harlequins star who finished second in the BBC Sports Personality of the Year awards after her breakout World Cup performances. "The media love to pit us against each other, but in camp we lift each other up," Sing explained. "She is incredibly fast and agile, while I bring a more physical presence – I’m roughly 10 kg heavier – and I add reliable goal‑kicking to the mix." Sing’s background is equally diverse: she holds a degree in bio‑veterinary science from Hartpury University and grew up on a Devon farm, a heritage she jokes gives her "farm strength" on the field. Statistically, Sing has been a prolific scorer. Over the past two league campaigns she topped the points table, primarily through accurate place‑kicking, and currently sits as the second‑highest points scorer in the season, trailing only Zoe Harrison. Her consistency earned her four player‑of‑the‑match awards, even after a recent knee injury sidelined her for a few games. Coach John Mitchell acknowledges the competition at full‑back but hints at a broader role for Sing. "We may explore her in the midfield," he said, noting her strong ball‑carrying and defensive fend. The prospect gains urgency after regular No 12 Tatyana Heard was ruled out with a foot injury. Former England captain Katy Daley‑McLean echoed the sentiment, observing that Sing’s traditional full‑back skill set – solid defence and dependable kicking – offers a different dynamic to Kildunne’s "X‑factor" flair. As the tournament approaches, Sing remains focused on translating her club form – highlighted by Gloucester‑Hartpury’s 22‑17 victory over Saracens in March – into more England starts. "I’m training hard and leaving the selection to Mitch; whichever style suits the game will win the shirt," she affirmed.

Israel's recent bombing of a densely populated residential area near Lebanon's largest public hospital, Rafik Hariri University hospital, has resulted in at least five deaths and 50 injuries. This attack is consistent with Israel's strategy in Lebanon, where human rights organizations and medical workers report that the IDF is targeting hospitals and medics, sometimes in ambulances or first aid centers.Israel's actions in Lebanon mirror its tactics in Gaza, where hospitals and medical equipment were destroyed, and medical workers faced extraordinary challenges, including forced evacuations and threats. The Israeli military claims that Hezbollah exploits medical facilities for 'terrorist activity,' but has not provided evidence to support these claims.The consequences of these attacks are dire. According to the World Health Organization, over 90 'attacks on healthcare' have been reported in Lebanon since March 2, resulting in 137 injuries and 53 deaths. These attacks have led to a crisis of trust in healthcare systems, with patients fearing that hospitals are no longer safe.The precedent set in Gaza and now Lebanon is a dangerous one for future conflicts. When even ambulances are targeted, the rules of engagement are being distorted. The international community must hold Israel accountable for these actions, which are crimes under international law.

British computer scientist Adam Back has vehemently denied claims that he is the elusive creator of Bitcoin, known as Satoshi Nakamoto. A recent report in the New York Times had suggested that Back was Nakamoto, but he quickly took to social media to refute the claims. In a thread on X, Back stated, 'I also don’t know who satoshi is, and I think it is good for bitcoin that this is the case, as it helps bitcoin be viewed [as] a new asset class, the mathematically scarce digital commodity.' This denial comes after a years-long effort to unmask Nakamoto, the mysterious author of the bitcoin white paper which laid the theoretical foundations for modern digital currencies. The speculation surrounding Nakamoto's identity has been ongoing for years, with previous attempts pointing to Nick Szabo, Hal Finney, and an 'unknown Australian genius' who was later revealed to be a fraud. The latest trail led to Back, a London-born computer scientist and entrepreneur, who was a member of an online anarchist cryptography community called the cypherpunks in the early 1990s. Journalist John Carreyrou claimed to have found similarities between Back and Nakamoto by analyzing decades of old internet postings and shared niche interests. However, Back attributed the similarities to 'a combination of coincidence and similar phrases from people with similar experience and interests.' Not everyone is convinced by Back's denial, with some speculating that he may still be Nakamoto. Stephen Murdoch, a professor of computer science at University College London, noted that while there are indications that it could be Back, 'there’s no smoking gun.' Meanwhile, Dr. Jacky Mallett, an assistant professor of computer science at Reykjavík University, suggested that Satoshi was 'almost certainly more than one person,' citing updates to the bitcoin code that suggest multiple contributors. Back is the owner of a bitcoin treasury firm that is merging with a publicly traded company. If he were indeed Nakamoto and the owner of 1.1m coins worth tens of billions of pounds, he would have to disclose this to the Securities and Exchange Commission, as it could materially affect the bitcoin market.