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The conflict between the US and Israel against Iran has taken a devastating toll on the country's healthcare system. At least 2,076 people have been killed and 26,500 wounded in Iran since the US and Israel first launched strikes on the country on February 28.Iranian President Masoud Pezeshkian has strongly condemned the attacks, appealing to international health organizations to respond to the crisis. On Thursday, he wrote on X: “What message does attacking hospitals, pharmaceutical companies and the Pasteur Institute as a medical research center in Iran convey?”The Pasteur Institute, a key center for medical research and vaccine production in Tehran, has been targeted. The institute, founded over 100 years ago in collaboration with the Institut Pasteur in Paris, conducts research on infectious diseases, produces vaccines, and provides advanced diagnostics.According to the World Health Organization (WHO), over 20 attacks on healthcare facilities in Iran have been verified since March 1, resulting in at least nine deaths, including an infectious diseases health worker and a member of the Iranian Red Crescent Society.Some of the facilities hit include:Red Crescent warehouse in Bushehr province, which was destroyed by a drone strike on Friday morning.Tofigh Daru Research and Engineering Company, one of Iran’s largest pharmaceutical companies, which was hit on March 31.Delaram Sina Psychiatric Hospital in Tehran, which was significantly damaged on March 29.Ali Hospital in Andimeshk, which sustained damage from an explosion on March 21.Gandhi Hospital in Tehran, which was damaged during attacks on a nearby television communications tower on March 2.International humanitarian law states that health establishments and units, including hospitals, should not be attacked. The United Nations Security Council resolution 2286 was adopted unanimously in 2016, condemning attacks on healthcare and calling on nations to respect international law.The attacks on healthcare facilities are not limited to Iran. Israel has also targeted healthcare facilities in Lebanon and Gaza, resulting in significant damage and loss of life.

President Donald Trump escalated rhetoric on Thursday, stating that the United States has yet to begin a full‑scale campaign against Iran’s remaining infrastructure and hinting that bridges and electric power plants could be next targets. The comment followed the release of video showing a U.S. strike on the newly completed B1 bridge that connects Tehran to Karaj, an attack that Iran reports killed eight people and injured 95. Iranian Foreign Minister Abbas Araghchi condemned the strike on civilian infrastructure, describing it as evidence of the “defeat and moral collapse” of the aggressor. In a statement posted on X, he warned that such attacks would not force Iran to surrender. The conflict, now entering its fifth week, has begun to ripple through regional and global markets. Instability around the Strait of Hormuz—a vital conduit for oil and gas—has prompted nations to scramble for alternative shipping routes. Satellite images this week captured smoke over Iran’s Qeshm Island, underscoring the heightened risk to infrastructure near the strategic waterway. Amid stalled negotiations with Iran’s new leadership, Trump’s intensified language comes as the United Nations Security Council prepares to vote on a resolution that could authorize member states to use “defensive means” to keep the strait open. Araghchi warned that any provocative action in the Council would only worsen the situation. Iranian media have begun listing potential retaliation targets, naming major bridges in Kuwait, Saudi Arabia, the United Arab Emirates and Jordan as possible future strike points. The semi‑official Fars News Agency highlighted these crossings as vulnerable following the Karaj bridge attack. The Islamic Revolutionary Guard Corps (IRGC) claimed responsibility for recent strikes on U.S.-linked industrial sites in the Gulf, including steel facilities in Abu Dhabi and aluminium plants in Bahrain. The IRGC warned that if attacks on Iranian industries continue, “the next response will be much more painful” and will focus on the occupier’s core infrastructure. Health infrastructure has also suffered. Iran’s Health Ministry reported that U.S. and Israeli raids severely damaged the Pasteur Institute of Iran, a key research center for diseases such as cholera and COVID‑19. Ministry spokesperson Hossein Kermanpour called the strike “a direct assault on international health security.” WHO Director‑General Tedros Adhanom Ghebreyesus echoed the condemnation, noting that the institute is now unable to deliver health services. The WHO has documented more than 20 attacks on Iranian healthcare facilities since the start of March. In a separate claim, Iranian officials said air defenses downed a second U.S. F‑35 fighter jet over central Iran, suggesting the pilot’s survival was unlikely. The United States has not responded to the allegation. Israel’s military reported a fresh barrage of Iranian missiles, which triggered air‑defence alerts and caused damage to homes, vehicles, and a train station in Tel Aviv. The widening hostilities, combined with threats to critical energy and health infrastructure, highlight the growing regional volatility and its potential to disrupt global markets.

In a scene reminiscent of Henry James’s observation that the only certainty with a young American abroad is surprise, the current US president continues to bewilder European partners with erratic statements.President Trump has publicly ridiculed British Prime Minister Keir Starmer and the Royal Navy as feeble, mocked French President Emmanuel Macron over personal matters, urged allies to secure their own oil supplies, and declared that withdrawing the United States from NATO is "beyond reconsideration". These comments come as the conflict in Iran, ignited by Trump and Israeli Prime Minister Benjamin Netanyahu, drags on without a clear resolution, fueling his domestic political anxieties.European officials responded not with shock but with weary irritation, noting that Trump’s unpredictability is now a permanent feature of US policy, steering the continent away from the liberal international order. Analysts warn that NATO’s credibility is eroding, turning the alliance into a "paper tiger" even as Russian President Vladimir Putin watches closely.Britain, hoping to serve as a diplomatic conduit between Washington and Brussels, finds its position increasingly precarious. Post‑Brexit economic vulnerabilities and the looming state visit of King Charles to the United States offer little strategic gain and risk becoming a diplomatic embarrassment.Prime Minister Starmer has deliberately avoided direct confrontation with Trump, instead pledging to deepen the United Kingdom’s economic and security ties with the European Union. This shift aims to reassure Labour factions leaning toward the Liberal Democrats and Greens, while also hoping that shared security concerns will coax European capitals into offering more robust economic support.In a world where traditional alliances are fraying, European leaders face mounting pressure to forge genuine security cooperation rather than merely increasing defence spending. The consensus is clear: delay is no longer an option for Europe to secure its own future.

The United States has reaffirmed that it is still prepared to engage Tehran in diplomatic talks, despite the ongoing US‑Israel war against Iran and President Donald Trump’s renewed threats to target the country’s civilian infrastructure. State Department spokesperson Tommy Pigott told Al Jazeera that President Trump had pursued negotiations with Iran before the conflict erupted, but accused the Iranian regime of persisting in its quest for a nuclear weapon. "The president is always open to diplomacy, but he’s also clear that we will see our objectives fulfilled here," Pigott said, underscoring the administration’s dual track of diplomatic engagement and military pressure. In a primetime address aired on Wednesday, Trump echoed his earlier claims that the United States is winning the war, yet offered no concrete roadmap for ending the hostilities or reopening the Strait of Hormuz – a chokepoint whose closure by Tehran has driven global energy prices higher. The conflict began on February 28, shortly after a round of Geneva talks that Omani mediators and Iranian officials described as “positive.” Last year, Israel struck Iran’s three primary nuclear facilities in an operation the White House dubbed “Midnight Hammer.” Iran continues to deny any intention to develop a nuclear weapon, while Israel is widely believed to possess an undeclared nuclear arsenal. Former intelligence chief Tulsi Gabbard testified to Congress that Iran was not rebuilding enrichment capacity before the June 2025 attacks, and later reiterated that there have been no efforts to restore its nuclear program since the strikes. Nevertheless, Tehran insists on the right to enrich uranium domestically and has ruled out negotiations over its missile program and support for groups such as Hezbollah and Hamas. Pigott emphasized that the United States is maintaining high‑level diplomatic contacts across the region, stating, "We see diplomatic engagement at the highest levels of this administration, with our partners in the region, to pursue our interests and explore what can happen here." The spokesperson also accused Iran of targeting civilians and civilian infrastructure, describing the threat of a nuclear‑armed Tehran as "intolerable." In response, Iran has launched missile and drone attacks against U.S. and Israeli assets, as well as energy facilities, hotels, and airports throughout the Middle East. Trump later posted footage of a U.S. strike on a major Iranian bridge, warning that similar attacks could follow. He wrote on social media, "IT IS TIME FOR IRAN TO MAKE A DEAL BEFORE IT IS TOO LATE, and there is nothing left of what could become a great country." In the same speech, he threatened to destroy Iran’s power plants and, earlier in the week, suggested the United States could also target water desalination stations – actions that legal experts say would constitute collective punishment under international law. Barbara Slavin, a distinguished fellow at the Stimson Center, told Al Jazeera that Trump appears to be "scrambling" to intensify the war in hopes of forcing a resolution before the conflict turns into a definitive failure.

The ongoing conflict between Israel and Iran has been a major concern in the Middle East, with escalating tensions and international diplomatic efforts aimed at de-escalation. Several factors could potentially bring an end to the conflict, including diplomatic negotiations, economic sanctions, and shifts in regional alliances. However, the situation remains complex and volatile, with multiple stakeholders involved and competing interests at play. The international community continues to monitor the situation closely, seeking to prevent further escalation and promote a peaceful resolution to the conflict.

The UK is leading a coalition of approximately 40 nations in virtual talks to address the ongoing blockade of the Strait of Hormuz by Iran. The waterway, crucial for global energy supply, has been blocked since the US and Israel initiated a war on Iran on February 28.The blockade has had severe economic repercussions, causing global oil prices to skyrocket above $100 per barrel, a roughly 40% increase from pre-war levels. This surge has forced countries, particularly in Asia, to implement fuel rationing and reduce industrial production. For instance, Malaysia has ordered all civil servants to work from home to conserve energy.The US has opted out of these talks, with President Donald Trump stating it's not the US's responsibility to reopen the strait, suggesting that European countries should secure their own oil. In response, UK Prime Minister Keir Starmer is chairing a video conference with over 40 countries, including France, the Netherlands, Germany, Italy, Canada, Australia, and the United Arab Emirates.The meeting's agenda includes assessing diplomatic and political measures to restore freedom of navigation, ensure the safety of trapped ships and seafarers, and resume the movement of vital commodities. The UK government has also outlined plans to clear the strait of landmines and protect tankers crossing the area.Experts suggest that while the coalition's efforts are crucial, the blockade's resolution is uncertain without an arrangement with Iran. Iran has demanded international recognition of its authority over the Strait of Hormuz as one of its conditions for a ceasefire. The country's parliament is also considering legislation to collect tolls from ships transiting the strait.Analysts argue that reopening the strait by force would require US and European allies to collaborate. However, under current circumstances, the coalition's success seems doubtful unless a negotiated arrangement with Iran is reached.

Thames Water is reportedly close to securing a pact with England and Wales’ water regulator, Ofwat, that would prevent the imposition of fresh fines for the next four years, contingent on a substantial commitment to upgrade its infrastructure.The proposal, first tabled in June 2025, originates from the utility’s creditors, who are keen to avoid a scenario where the struggling company is temporarily renationalised. These lenders had already injected £3 bn of emergency financing last year to keep the business afloat.Having amassed a £17.6 bn debt burden since privatisation, Thames Water has been battling potential insolvency for over two years. A previous attempt to sell the firm collapsed when the preferred bidder, KKR, pulled out at the last minute.Under the contemplated agreement, Ofwat would accept “undertakings” from Thames Water, meaning the company would focus on rectifying the underlying service failures rather than paying penalties to the government. However, the deal would not shield the utility from possible sanctions by the Environment Agency or from ongoing legal actions.Pressure is mounting as Thames Water is projected to run out of cash in October, intensifying the urgency of reaching a resolution. Any settlement must undergo a three‑month public consultation, a process likely to attract criticism given that customer water bills are set to rise by more than a third by 2030, before accounting for inflation.Creditors have pledged that all outstanding fines will be settled and that regulators will gain greater transparency and accountability over the company’s efforts to curb pollution, leakage, and other performance targets introduced a year ago.Thames Water itself emphasised a “market‑led solution” that delivers swift improvements for both customers and the environment while progressing its operational and financial turnaround plan. The utility highlighted that it has launched its largest upgrade in 150 years, allocating a record £1.26 bn in capital investment—a 22% year‑on‑year increase in the first half of the 2025‑26 financial year—focused on fixing leaks, reducing pollution, and enhancing water quality.An Ofwat spokesperson noted that the regulator is carefully reviewing the creditors’ plans to ensure they produce a genuine turnaround in performance and bolster the company’s financial resilience for the benefit of both customers and the environment.

Britain is confronting the most severe energy shock since the early 1970s, as exports of oil, gas and fertiliser from the Middle East have abruptly stopped. The government says a response plan exists, but details remain vague. It is unclear whether the UK is better prepared for the fallout from Donald Trump’s war with Iran than it was for the pandemic six years ago. Ministers are sending a "we have your back" message to the public while simultaneously signalling to financial markets that any assistance will be limited and targeted. Contingency planning is especially difficult when dealing with an unpredictable leader like Trump. Britain’s heavy reliance on imported energy and food means that reassurance can only hold for a short time. The economy entered the conflict already on shaky ground: unemployment rose steadily throughout 2025 and growth stalled to a virtual standstill in the final quarter of that year. The sudden loss of Middle‑East energy and fertiliser supplies now adds a colossal supply shock. Last year, Trump’s “liberation day” tariff hikes served as a dry run for a far more serious confrontation. This time, the war is taking place in a region that is both volatile and crucial to the global economy. In the past two weeks, the repercussions have been felt across Asia – the Philippines declared a state of emergency, Sri Lanka introduced a four‑day work week, and South Korea announced budget measures to help households cope with soaring energy bills. The continent is the most dependent on Gulf‑exported energy, making the impact there the sharpest. The International Monetary Fund warned that the shock will drive higher prices and slower growth worldwide. Shortages push fuel and food prices up, eroding disposable income, prompting businesses to cut staff, and increasing the risk of recession. The UK, already projected to be one of the poorest‑performing major economies in 2026, could see its fresh graduate cohort face a brutal job market. Trump’s claim that the war could end within two or three weeks appears desperate. Even a rapid cease‑fire would leave substantial collateral damage, creating a stagflation scenario that could hurt Republican prospects in the upcoming mid‑term elections. British officials hope a swift resolution will limit economic damage, allowing a short‑term inflation spike to subside and the Bank of England to resume interest‑rate cuts. Treasury plans include scrapping the planned autumn fuel‑duty rise and providing targeted help for the poorest households, though the path is unlikely to be that simple. Currently, the Treasury is hesitant to act boldly for fear of unsettling bond markets. History – the 2008 banking collapse and the 2020 pandemic – shows that governments can act decisively without triggering a market backlash, using tools such as aggressive rate cuts, increased borrowing, and quantitative easing. The Bank of England has warned of a "substantial negative supply shock" and is expected to soften markets for future rate cuts, which are inevitable. Finance Minister Rachel Reeves could mitigate labour‑market pain by reversing recent increases in employers’ National Insurance contributions, subsidising public transport, and even lowering speed limits to conserve energy. The war, like the pandemic and Russia’s invasion of Ukraine, underscores the fragility of global supply chains and the need for greater British self‑reliance. Investing heavily in renewable energy is essential, but the UK also imports roughly 40% of its food and has not run a manufacturing trade surplus since 1982. In a world of disrupted supply lines, a robust plan for economic self‑sufficiency is more urgent than ever. Larry Elliott is a Guardian columnist.

Global markets were jolted on Thursday as oil prices skyrocketed and stocks sank following a televised address by Donald Trump, in which he vowed to take 'extremely hard' action against Iran in the coming weeks. This development has dashed investor hopes of a swift resolution to the conflict in the Middle East.Brent crude prices jumped by 8% to surpass $109 a barrel, reversing the previous day's decline when hopes of de-escalation had briefly pushed the international benchmark below $100 a barrel.Asian markets were particularly hard hit, with Japan's Nikkei index falling 2.4%, China's CSI 300 index dropping 1.36%, and South Korea's Kospi tumbling 4.8%. In Europe, Germany's Dax fell 2%, France's Cac 40 dropped 1.15%, and Italy's FTSE Mib was down 1.45%. The FTSE 100 in London initially opened 0.7% lower but later stabilized, buoyed by gains in fossil fuel companies BP and Shell, which rose 4.5% and 3.1% respectively.Government borrowing costs also increased, with the yield on 10-year UK gilts rising four basis points to 4.886% and the two-year UK bond yield rising six basis points to 4.36%, reflecting growing fears of inflation due to higher energy costs.Chris Beauchamp, chief market analyst at IG, noted that investors are betting on the impact of delayed oil supply deliveries from the Gulf, given Trump's failure to provide guidance on a potential end to the US-Israeli conflict with Iran. 'Instead of 'no more war', we got 'no, more war!', Beauchamp said, highlighting the market's concerns about hundreds of millions of barrels of oil that may not be delivered soon.The US dollar gained 0.6% against a basket of major currencies as investors sought safe-haven assets, pushing the pound down by almost a cent to $1.321. The market turmoil is already affecting consumers, with the Bank of England warning that 1.3 million more homeowners may see their mortgage payments rise due to financial shocks from the Iran conflict.Additionally, data from the RAC showed that petrol and diesel prices jumped by a record amount in March, with the average price of a litre of unleaded petrol rising by 20p to 152.83p by the end of the month, surpassing the previous monthly record.