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The Guardian’s latest science podcast examines the worldwide campaign to wipe out Guinea worm disease, a parasitic infection that could become the second human disease ever eradicated after smallpox. Hosted in 2026, the episode highlights why the disease remains a focal point for public‑health leaders and what its elimination would mean for global health security.Guinea worm, transmitted through contaminated water, has been the target of an intensive eradication effort led by the World Health Organization and partners in endemic regions. The podcast underscores the progress made: cases have plummeted from millions in the 1980s to just a handful today, illustrating the power of coordinated surveillance, safe‑water interventions, and community education.Despite the gains, experts caution that complete eradication is not guaranteed. Residual hotspots in remote villages, logistical challenges in delivering clean water, and the need for sustained funding pose ongoing risks. The discussion stresses that a lapse in commitment could allow the parasite to rebound, undoing decades of progress.Historically, smallpox remains the only disease humanity has fully eradicated, a milestone achieved in 1980 after a global vaccination campaign. The potential success of the Guinea worm program would mark a watershed moment, demonstrating that eradication is feasible beyond vaccine‑preventable illnesses and could inspire similar initiatives for other neglected tropical diseases.Listeners are encouraged to support the effort through the Guardian’s science podcast platform, where additional resources and ways to contribute are provided. As the episode concludes, the hosts reiterate that the fight against Guinea worm is both a test of global solidarity and a template for future disease‑elimination campaigns.

A devastating fire swept through a coastal village in Malaysia's Sabah state, destroying approximately 200 homes and leaving hundreds of people without a place to live.The fire broke out in the Sandakan district at around 1:32 AM on Sunday (17:32 GMT, Saturday), according to the district's fire and rescue chief, Jimmy Lagung. The blaze spread rapidly due to strong winds and the close proximity of the houses, which are built on stilts in one of Sabah's water villages.The affected community includes some of the country's poorest residents, such as stateless and indigenous groups. As of now, about 445 people have been displaced and are registered at a temporary relief center in Sandakan.The head of the Sandakan District Disaster Management Committee, Datuk Walter Kenson, stated that the homes of the affected residents are no longer safe to live in. In response, Malaysia's Prime Minister Anwar Ibrahim announced that the federal government is coordinating with Sabah authorities to provide basic assistance and temporary relocation for those affected.The priority, according to the Prime Minister, is the safety of the victims and immediate assistance on the ground. The government is working to address the immediate needs of the displaced individuals.

Tens of thousands of displaced Lebanese families have begun returning to their homes in southern Lebanon, despite ongoing Israeli attacks and home demolitions near the border. The return comes after a 10-day truce between Lebanon and Israel.On Saturday, a steady stream of vehicles carrying mattresses, bags, and flags was seen traveling south as families evaluated the condition of their homes. However, many found their homes destroyed or damaged beyond habitation, making them hesitant to stay.The Lebanese army has advised residents to postpone their return, while Hezbollah has warned that it has its "finger on the trigger" should Israel breach the agreement. Senior Hezbollah official Mahmoud Qamati cautioned that "Israeli treachery is expected at any time, and this is a temporary truce".Lebanese authorities report that nearly 2,300 people were killed and over one million displaced throughout the conflict, primarily from southern Lebanon and Beirut's southern suburbs. Local media and residents indicate that Israeli forces continue demolition operations across several border villages.The Israeli military has established a "Yellow Line" in southern Lebanon, similar to what it did in the Gaza Strip, designating a military zone and buffer inside the area.

Israel and Lebanon dispute a new 10‑km “Yellow Line” zone in southern Lebanon, set up hours after a 10‑day ceasefire began Thursday night after 46 days of Israeli bombardment, prompting legal concerns.The ceasefire, intended to halt 46 days of Israeli air strikes and a ground incursion, was quickly undermined as Israeli troops carried out demolitions, artillery shelling and land‑clearing operations in border villages, actions that many observers say breach the agreement.Israel describes the zone as a reinforced security buffer extending roughly 10 km north of the border, intended to "root out Hezbollah" and remain under Israeli control. Prime Minister Benjamin Netanyahu emphasized that the strip is "much stronger, more intense, more continuous and more solid" than any previous arrangement and that Israeli forces will not withdraw.Lebanese officials and Hezbollah reject the move, labeling it an occupation of sovereign territory that violates the ceasefire's premise. The group warned that any unilateral Israeli actions would be met with resistance and called the truce "an insult to our country."Analysts note that the ceasefire text contains contradictory clauses: it calls for a cessation of hostilities while simultaneously preserving Israel's right to take "all necessary measures in self‑defence" against "planned, imminent, or ongoing attacks." This wording, according to Al Jazeera’s Heidi Pett, gives Israel broad latitude to interpret threats and continue operations.Since the ceasefire’s start, Israeli forces have launched air strikes targeting alleged fighters near the Yellow Line and have demolished homes in the town of Haneen. Artillery fire has also been reported near Beit Lif, al‑Qantara and Toul, and bulldozers continue land‑clearing work across several southern Lebanese villages.Hezbollah has linked the ceasefire to broader regional diplomacy, noting that a stable truce in Lebanon is a prerequisite for any meaningful US‑Iran talks. Iranian officials have echoed this stance, warning that continued Israeli aggression could jeopardise future negotiations.Some commentators, such as Abed Abou Shhadeh, argue that Israel may be using the Yellow Line as leverage for future talks, potentially turning a temporary buffer into a longer‑term occupation—mirroring Israel’s historic hold on the Shebaa Farms, the Syrian Golan Heights and parts of the West Bank.Both Israeli and Lebanese officials publicly affirm that the ceasefire remains in effect, yet the ongoing military activities suggest a de‑facto erosion of its terms, raising fears among Lebanese citizens that the "Yellow Line" could become a permanent foothold for Israeli forces inside Lebanon.

Israeli forces announced on Saturday, April 18, 2026, that they have established a “yellow line” in southern Lebanon to deter perceived terrorist incursions and reinforce a 10‑day ceasefire that began on Thursday. The Israeli Defence Forces (IDF) said troops operating south of the newly‑drawn line identified militants violating cease‑fire understandings and advancing from north, posing an "immediate threat." Violations, the IDF claimed, justify self‑defence actions not limited by the truce. This is the first instance the IDF has used the term “yellow line” outside the Gaza Strip, where a similar demarcation has split the territory into heavily controlled eastern zones and relatively freer western areas since the October 2023 ceasefire. In Gaza, the line has been enforced with lethal force and extensive house demolitions; analysts fear a comparable approach could be applied in Lebanon. Al Jazeera’s Nour Odeh described the move as a continuation of the “Gazafication” of southern Lebanon, noting Israeli Defence Minister Israel Katz has instructed the army to demolish border villages using the “Beit Hanoon and Rafah models.” She warned that Lebanese Shia villages could be treated as equivalent to Hamas‑run areas in Gaza. Despite the ceasefire, Israeli artillery struck the Lebanese towns of Beit Leif, Qantara and Touline on Saturday, and demolition crews continued razing homes. The IDF justified these attacks as pre‑emptive actions against fighters approaching Israeli positions, stating that “actions taken in self‑defence and to remove immediate threats are not restricted by the ceasefire.” Hezbollah Secretary‑General Naim Qassem responded, insisting that a ceasefire must be reciprocal. “There is no ceasefire from the side of the resistance only; it must be from both sides,” he said, adding that the group will remain armed until Israel fully withdraws from southern Lebanon. Qassem outlined a roadmap for post‑truce steps: release of prisoners, return of displaced residents, and a large‑scale reconstruction effort backed by Arab states. He also signalled openness to a new political chapter for Lebanon, provided national sovereignty is respected. The latest truce follows a previous agreement dating back to November 27, 2024, which the United Nations says has been breached over 10,000 times by Israel, resulting in hundreds of Lebanese casualties. Israel continues to demand Hezbollah’s disarmament as a precondition for a lasting peace, while the Lebanese government, under President Joseph Aoun, remains wary of both Hezbollah’s influence and Israeli incursions. In a diplomatic development, U.S. President Donald Trump announced that Israeli Prime Minister Benjamin Netanyahu and President Aoun could meet in Washington within the next two weeks to discuss ending hostilities. The proposed talks could shape the future of the “yellow line” policy and the broader stability of the Israel‑Lebanon frontier. Analysts warn that the introduction of a “yellow line” in Lebanon may signal a shift toward harsher border enforcement, echoing Gaza’s restrictive regime. If Israel proceeds with village demolitions, the move could exacerbate humanitarian concerns and fuel further resistance, undermining the fragile ceasefire and regional security.

The conflict between Israel and Lebanon has led to a significant humanitarian crisis, with at least 2,196 people killed and over one million displaced in Lebanon. The ceasefire, announced by US President Donald Trump, aims to facilitate negotiations for a more permanent security and peace agreement.The truce came into effect at 21:00 GMT and includes Hezbollah, a Lebanese armed group backed by Iran. However, ceasefire violations have been reported by Lebanese forces, with several Israeli attacks recorded and intermittent shelling targeting villages.The terms of the ceasefire agreement allow Israel to preserve its right to self-defense while not carrying out offensive military operations. Israel's Prime Minister Benjamin Netanyahu stated that the agreement does not preclude Israel's demand for the disarmament of Hezbollah.The ceasefire has been met with skepticism by some, with former Israeli diplomat Alon Pinkas expressing doubts about Netanyahu's commitment to the agreement. Hezbollah has also urged caution, with Ali Fayyad stating that the group will approach the ceasefire with vigilance.The conflict has significant implications for the region, with US-Iran negotiations potentially influencing the situation. Trump's announcement of the ceasefire coincided with his statement that a deal to end the war on Iran was 'very close'.

Following a 10-day truce agreement between Lebanon and Israel, tens of thousands of displaced Lebanese have begun returning to their homes in southern Lebanon. The truce, which came into effect on Friday, has brought a fragile calm to the region, with many residents eager to assess the damage to their homes and communities.Despite the ceasefire, Lebanon's army has accused Israel of several early violations, including intermittent shelling of southern Lebanese villages. Hezbollah has warned that it has its 'finger on the trigger' in case of Israeli violations, while French President Emmanuel Macron has expressed concerns that the ceasefire 'may already be undermined by ongoing military operations.'The conflict has resulted in over 2,100 deaths and 1.2 million displaced in Lebanon, according to Lebanese authorities. Israeli Defence Minister Israel Katz has stated that the ceasefire does not mean Israel's campaign against Hezbollah is over, and that the group's fighters will have to be disarmed one way or another.As residents return to their hometowns, some have pledged to stay, while others have expressed fears that the fragile truce could collapse. The ceasefire could ease tensions in US-Iran negotiations, with Iran viewing the regional conflict as interconnected.

The Premier League weekend fixtures are set to kick off with several highly anticipated matches. Brentford will face Fulham on Saturday at 12:30 PM at the Gtech Community Stadium. The referee for this match is Paul Tierney, who has given an average of 3.75 cards per game this season. In another match, Leeds will host Wolves at Elland Road on Saturday at 3 PM. The referee for this fixture is Tim Robinson, who has given an average of 4.22 cards per game this season. Newcastle will welcome Bournemouth to St James' Park on Saturday at 3 PM. The referee for this match is Tom Bramall, who has given an average of 4.05 cards per game this season. Tottenham will host Brighton at the Tottenham Hotspur Stadium on Saturday at 5:30 PM. The referee for this fixture is Stuart Attwell, who has given an average of 4.85 cards per game this season. In a highly anticipated match, Chelsea will face Manchester United at Stamford Bridge on Saturday at 8 PM. The referee for this match is Michael Oliver, who has given an average of 3.04 cards per game this season. On Sunday, Aston Villa will host Sunderland at Villa Park at 2 PM. The referee for this fixture is Sam Barrott, who has given an average of 3.63 cards per game this season. Everton will welcome Liverpool to Goodison Park on Sunday at 2 PM. The referee for this match is Chris Kavanagh, who has given an average of 3.88 cards per game this season. Nottingham Forest will host Burnley at the City Ground on Sunday at 2 PM. The referee for this fixture is Tom Kirk, who has given an average of 4.50 cards per game this season. In the final match of the weekend, Manchester City will host Arsenal at the Etihad Stadium on Sunday at 4:30 PM. The referee for this highly anticipated match is Anthony Taylor, who has given an average of 3.92 cards per game this season. The Monday night match features Crystal Palace hosting West Ham at Selhurst Park at 8 PM. The referee for this fixture is Darren England, who has given an average of 4.47 cards per game this season.

Marcus Rashford's future at Manchester United hangs in the balance as his loan spells at Aston Villa and Barcelona come to an end. The 28-year-old has not played for United since December 2024 and is currently on loan at Barcelona, who have the option to purchase him for €30m (£26m).Manchester United sit comfortably in third place in the Premier League, seven points above sixth-placed Chelsea, but will not want to see the gap close come full time at Stamford Bridge. A return to Europe's top table is vital for United, which would result in players' wages increasing, including Rashford's salary reaching £325,000 per week on his deal, which runs until 2028.Michael Carrick, United's manager, has stated that the door is not completely closed on Rashford playing for United again. 'There's decisions to be made in time on certain things, and obviously Marcus is in that situation. But at this point in time, nothing's been decided,' Carrick said. 'Certainly from my perspective, whoever's here I want to work with, make the best out of, and help them improve.'Rashford's situation is complicated by United's desire to sell him, but few clubs could match his current earnings. Carrick will want to see his team bounce back from Monday night's home defeat by Leeds, but faces a defensive crisis with Harry Maguire and Lisandro Martínez out of the lineup.