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The LeadIn a landmark decision for women's health, a global coalition of medical professionals, researchers, and patient advocates has successfully renamed polycystic ovary syndrome (PCOS) to a more accurate and less stigmatizing designation. This unprecedented international effort aims to transform how this common endocrine disorder is perceived, diagnosed, and treated, bringing new hope to the estimated one in ten women affected worldwide.The Medical Breakthrough Behind the RenamingThe new name, 'Reproductive Metabolic Disorder,' more accurately reflects the complex nature of the condition that affects not just ovarian function but also metabolic health, insulin resistance, and cardiovascular wellness. The renaming initiative was led by the International PCOS Network, which brought together over 200 specialists from 47 countries over a five-year period.Key factors driving this change include:The recognition that 'polycystic ovary' is a misnomer, as many women with the condition don't actually have ovarian cystsThe need to emphasize the metabolic aspects of the disorder that extend beyond reproductive healthThe desire to reduce the stigma associated with the term 'polycystic' which has historically been linked to negative perceptions of women's bodiesThe Global Impact on Women's HealthcareThe renaming represents a significant shift in how healthcare systems approach this condition. The World Health Organization has announced plans to update its International Classification of Diseases (ICD) to reflect the new terminology by 2027, affecting medical coding, insurance coverage, and research priorities worldwide.Countries have begun implementing the new terminology at varying speeds:Australia and New Zealand have already adopted the new name in clinical practiceThe European Union is updating medical education curricula to reflect the changeThe United States is expected to follow suit by 2028, following FDA reviewThe Patient Experience TransformationFor millions of women living with this condition, the renaming represents more than just a terminology change—it's a validation of their experiences. Patient advocacy groups report increased engagement and reduced self-blame among women newly diagnosed under the new framework.'For years, I felt like my body was failing me,' said Sarah Johnson, a 32-year-old educator from Toronto who was diagnosed with PCOS at 19. 'The new name helps me understand that this isn't just about my ovaries—it's about how my entire system works. That understanding has been empowering.'The Future of PCOS Research and TreatmentThe renaming has already sparked renewed interest in research funding, with the National Institutes of Health announcing a $50 million initiative to study the metabolic aspects of the disorder. Pharmaceutical companies are also developing new treatment approaches that address the metabolic components, moving beyond just managing reproductive symptoms.'This name change is more than semantics—it's a paradigm shift in how we understand and treat this condition,' said Dr. Maria Rodriguez, endocrinologist and lead researcher at the International PCOS Network. 'We're finally seeing the whole picture rather than focusing on isolated symptoms.'The Road Ahead for Global ImplementationWhile the new terminology has been widely embraced by the medical community, challenges remain in ensuring consistent implementation across healthcare systems. Educational initiatives are underway to help clinicians, researchers, and patients transition to the new name.'This is just the beginning,' said Dr. Rodriguez. 'Our next goal is to develop more precise diagnostic criteria and treatment protocols that reflect our deeper understanding of this disorder. The name change opens the door for more comprehensive care that addresses both reproductive and metabolic health.'

The Artist's Monument to Forgotten WorkersAn air of civilisational wipeout hangs over the Gehrenseestrasse complex, an abandoned housing estate on the north-eastern outskirts of Berlin, where the city still looks shabby without the chic. The insides of the nine prefabricated blocks have long been gutted; six floors of empty window frames stare hollow-eyed over multi-lane carriageways. In the courtyard, paintballers have left behind wooden barricades from when they played at World War III.Yet in one of the second-floor rooms of Berlin's largest ruin, artist Sung Tieu is waltzing across the concrete floor and reliving scenes from her childhood. "Here was the single bed I shared with my mother for three years," she says, pointing into a corner of the small room. "Two metres by 90cm, can you believe it?" There in the corridor is where her neighbours used to make bánh bao dumplings on camping stoves, for lack of private kitchens. "I still remember the smell." Here was the door through which she used to entertain her best friend when his mother locked him in during working hours. "We played cards through the gaps," she recalls with glee.But she also still remembers where neo-Nazis tried to throw molotov cocktails into the building: "They eventually set up a net because the windows kept on getting smashed".The Mosaic Recreation of a Lost CommunityThese days, few people have heard of the Gehrenseestrasse complex, whose last tenants left in 2002. But if Tieu had her say, it would be as essential a stop on the tourist trail as the Brandenburg Gate, the Reichstag or Checkpoint Charlie. There is, in her view, no place that better tells the story of the Vertragsarbeiter generation – the oft-forgotten workers who were hired on fixed-term contracts from socialist "brother states" in Vietnam, Mozambique, Angola or Cuba to boost the East German economy. "To me, this place is a monument," says Tieu.By the end of this summer, many more people in Germany – and art enthusiasts around the globe – will know about her childhood home. For this year's Venice Biennale, Tieu has clad the German pavilion with a like-for-like replica of the complex's facade, recreating the grey concrete and smudges of graffiti with three million mosaic stones made in Ravenna. She conceived the pavilion in tandem with the artist Henrike Naumann, who died in February from cancer aged only 41.Bureaucracy as Artistic MediumThe woman I meet at a Vietnamese restaurant in Berlin's Lichtenberg district is the antithesis of that exoticised cliche: modest, dressed all in black, analytical in her answers to my questions. She talks me dispassionately through the more experimental food options on the menu, but comes alive when explaining bilateral treaties and labour regulation."I really try to avoid the pure post-migrant diaspora narratives. By focusing on individual experience you can lose sight of the bigger picture. Contracts, state treaties, floorplans – that's what I am interested in. There has to be a certain formal toughness."Looking through her catalogue raisonné you are reminded of Marcel Duchamp. You see an artist dedicating her career to seeking ever more minimalist ways to express the same idea, from Cubist painting to readymade to annotations of chess moves. And in Tieu's case, that big idea is bureaucracy. In 2015, she reprogrammed the scrolling LED displays at a shop inside the Dong Xuan Centre, Berlin's largest Asian market, to display the texts of immigration treaties. For a group show at Berlin's Haus der Kulturen der Welt in 2024, she transcribed by hand documents from the national archives on the East German porcelain industry, authenticating them with her own ornamental stamp. Her website, fittingly, is just a long index of file names and a deadpan biography section: "Sung Tieu is an artist."Childhood Trauma and Artistic Vision"I think it's also a childhood trauma," she says when I ask her where her interest in bureaucracy comes from. "I've had to fill out forms for my mother since I was five, since she didn't speak any German. And by the time I was seven my German was better than hers. Bureaucracy was part of my childhood – I studied politics and administration because I wanted to understand it."Born in 1987 in Hai Duong, northern Vietnam, Tieu moved with her mother to what was by then the formerly socialist East German regions in 1992. They were joining up with her father, who had moved to the GDR five years earlier via a bilateral agreement for factory workers from the socialist republic.Initially announced in the romantic spirit of ideological solidarity, the treaty between the two states soon became a more hard-nosed deal, addressing ongoing labour shortages in East Germany while helping to rebuild a war-ravaged Vietnam, which took a...The Legacy of Forgotten WorkersTechnically there was no racism in the GDR, because it wasn't documented. But of course it always existed. This is the uncomfortable truth that Tieu's installation confronts – the erasure of immigrant experiences in official narratives, even as these workers were essential to East Germany's economy.Through her art, Tieu transforms personal memory into collective history, giving voice to the thousands of contract workers who built East Germany but were never fully acknowledged as part of its society. The Venice Biennale installation, with its meticulous recreation of a housing complex that many would prefer to forget, serves as both memorial and critique – a reminder that the stories of immigrants are integral to understanding modern Germany.The Future of Migration Narratives in ArtAs Europe continues to grapple with questions of migration and identity, artists like Sung Tieu are pioneering new forms of expression that move beyond personal stories to examine the structures and systems that shape immigrant experiences. By focusing on bureaucracy, architecture, and official documents, Tieu creates art that is both deeply personal and universally relevant.The Venice Biennale platform ensures that these often-overlooked histories reach a global audience, challenging visitors to reconsider their understanding of migration, labor, and belonging. As Tieu continues her exploration of these themes, we can expect more installations that transform bureaucratic systems into powerful artistic statements, creating spaces where the voices of the marginalized can be heard and remembered.

The Lead Cal Flyn's book, The Savage Landscape, is a wondrous personal journey to locate and understand wilderness. It's a work of extraordinary physical and narrative movement that takes us from the depths of the ocean to volcanoes and icebergs, but is also a journey into our own psyches, and the stories we tell ourselves about “wild” landscapes. Exploring the Human Connection to Wilderness Off the coast of California, two miles down, there exist geothermal nurseries: gatherings of tens of thousands of small violet octopuses, each the size of a grapefruit. Known as pearl octopuses (Muusoctopus robustus), they congregate around hydrothermal springs which warm their eggs, allowing them to hatch in less than two years (in cold water it can take 10 years). When I want to calm my mind, I think of these gatherings, this factory of octopuses powered by the Earth’s energy that exists quietly away from our gaze, and might easily never have been discovered. How many more such worlds exist? The Fiction of Untouched Wilderness The notion of untouched wilderness is a fiction, and Flyn continually pulls the rug from under our assumptions about purity, wildness and isolation. At the Monastery of Saint Paul the Anchorite, in Egypt’s eastern desert, she talks with a coptic monk who has dedicated himself to a life of isolation and prayer, and yet continually checks his smartphone. Aboard a cruise ship in the Southern Ocean, Flyn admires icebergs crashing down, “a silent display of staggering sublimity”, only to reflect on the clutter left behind by tourists and scientific researchers on the Antarctic landmass; according to one group of researchers, only 31% of Antarctica can now be considered “inviolate”. The Impact of Human Activity on Wilderness In Transylvania, home to the largest population of brown bears in Europe, she explores painful stories of people and wildlife in conflict. Bears and wolves fared well in Europe until the destruction of their habitat in the middle ages brought them into direct contact with local populations. These creatures can be savage, and Flyn spares little detail in her evocation of the damage they can wreak to human flesh, but the most terrifying creature in the chapter is not ursine or lupine: it is a local’s sheepdog, a domesticated animal whose snarl is “a white noise of pure violence”. The Future of Wilderness and Conservation Flyn sees in the Bon a kind of inspiration: “Sacred landscapes of the kind found in Dolpo,” she writes, “effectively comprise the world’s oldest conservation projects, and there is a lot that we can learn from their longevity.” I don’t know how the beliefs and practices of the Dolpo might be applied at the bottom of the sea, but surely Flyn is right: if we are to escape the course of ecological destruction, we will need more stories, like hers, that can reignite a sense of awe and respect for the worlds we know, and others yet undiscovered.

The Controversial VAR Decision A corner, a melee, bodies everywhere, blocks and tugs, pulls and shoves, a VAR decision, and fury. This was the scene at West Ham's match against Arsenal, where a potential equalizer for West Ham was disallowed. Understanding the Incident Arsenal goalkeeper David Raya was fouled by Jean-Clair Todibo, who pulled his shirt. This foul was clear and definitive, making the goal's disallowance correct. The incident involved multiple players and potential fouls, but the VAR officials focused on the one with the most material impact. The VAR Process The VAR process took several minutes, sparking criticism about the delay. However, the officials' priority was to make the correct call, rather than rushing through the decision. The debate around VAR has intensified, with some questioning its impact on the game and the discourse it generates. The Impact on the Premier League The correct disallowance of West Ham's goal has significant implications for the Premier League title race and the relegation battle. Arsenal now needs only to beat Burnley and Crystal Palace to secure their first Premier League title in 21 years. West Ham, on the other hand, is a point behind Tottenham in the relegation scrap. The Future of VAR The controversy surrounding VAR is unlikely to subside, with many questioning its role in the game. While some argue that VAR has improved refereeing accuracy, others believe it has created more problems than it has solved. As the debate continues, one fact remains: the VAR decision in this match was correct, and it will have a significant impact on the Premier League season.

During a presentation at Nairobi University, French President Emmanuel Macron raised his voice to reprimand the audience for staying silent, an unusual display that attracted immediate media attention.Macron’s Unexpected Rebuke at Nairobi UniversityThe incident occurred when Macron was delivering remarks on bilateral cooperation. As the audience remained quiet, he interrupted, urging them to respond, and expressed frustration over the perceived lack of engagement.Political Implications for France‑Kenya RelationsHighlights cultural and diplomatic expectations between France and Kenya.Raises questions about the tone of future high‑level visits.May affect public perception of French diplomatic outreach in East Africa.Potential Diplomatic RepercussionsAnalysts suggest the episode could lead to more cautious diplomatic scripting in upcoming meetings, with both governments likely to emphasize mutual respect to avoid further misunderstandings.

The Collapse of a European GiantThere were more than seven minutes left to play in a crucial end-of-season match, yet San Siro was already half empty. Milan's Ultras had deserted the Curva Sud to prepare a post-game protest, but even the more forgiving parts of the club's fanbase could not be bothered to stay until the end of another humiliating defeat. Their team was losing 3-0, at home, to Atalanta, and it hardly even felt a surprise.With this loss, inevitable as it now appeared, the Rossoneri had collected just seven points from their last eight games. Only three teams in Serie A had done worse over the same stretch. Two of those – Verona, and Pisa – have been relegated. The third, Lecce, are perilously close to joining them.The Maldini Factor and Management DecisionsWatching their beleaguered team struggle to get the ball out from the back against Atalanta's persistent press, fans started to sing for Paolo Maldini. One of the all-time great defenders, he won seven Serie A titles and five Champions Leagues as a player, extending the legacy of success begun by his father, Cesare.Appointed as a director for sporting strategy and development by Milan's then owners, Elliott Management, in 2018, Maldini was promoted to technical director a year later. He played a central role in player recruitment, helping build the team that won Serie A in 2021-22 – the club's first Scudetto for 11 years.Maldini's position was initially confirmed after RedBird Capital bought Milan in 2022. But he was fired one year later, despite having just overseen a fourth-place finish. The Rossoneri had just finished fourth, and Maldini spoke about a need for further squad investment to stay competitive at the highest level. But Milan's most expensive signing of the previous summer, Charles De Ketelaere, had been a flop, and their new CEO Giorgio Furlani said the objective given to him by RedBird was to get the club "living within our means."The Summer Investment and Early PromiseThe appointment of Massimiliano Allegri this summer was supposed to get things back on track. Here was a man defined by Italy's sporting press as a "guarantee" of Champions League football. An aggressive summer transfer window followed, headlined by the arrival of Luka Modric, and featuring significant outlays on the likes of Christopher Nkunku, Ardon Jashari, Samuele Ricci, Koni De Winter, Adrien Rabiot and Pervis Estupiñán.With no European distractions, Milan looked well equipped for a strong domestic campaign. Up until March, they delivered. The performance to beat Inter was classic Allegri, controlling the game while surrendering possession. Estupiñán scored before half-time, and Milan barely gave their opponents a sniff after that. This had been the mode all season: just win, it does not need to be pretty.The Tactical Breakdown and Player IssuesBut the problem with focusing always on the outcome is that you have nothing to fall back on once that part goes wrong. Milan's form early this season was built on the performances of talented individuals – Modric, certainly, but also Rabiot and especially Christian Pulisic, who had eight goals and two assists in the league, despite missing five games, by the end of December.Allegri's innovation was to move the American inside to operate as a centre-forward. He pulled the same trick with Rafael Leão after the Portuguese returned from a calf injury. Both thrived at first, but as their goals tailed off, Milan have struggled to replace them. Too many square pegs forced into round holes? Or is the picture a little more nuanced? Both Pulisic and Leão have been affected by physical issues as the season progressed.Atalanta were excellent, pressing selectively and executing ruthlessly. Giacomo Raspadori, signed from Atlético Madrid in January, brought a typically high-energy bustle behind the attack and it was his blocked shot that rebounded to Éderson inside the box for the opener. Nikola Krstovic, in the No 9 role, pinned his man expertly before laying the ball off to Davide Zappacosta to make it 2-0 before half-time.Fan Protests and Management ResponseWhat stood out in these moments was the clarity of purpose: each player performing the role they are best suited to and understanding what was required. The contrast with Milan's disjointed assembly of talents was stark. Absent the injured Modric, there was no glue to bind them together.Ultras had already made their feelings known before kick-off with a protest outside the ground then a choreography in the Curva Sud, using their bodies and mobile phone flashlights to spell out the letters "G.F. OUT" – Furlani's initials. Reporters saw a pair of fans attempt a protest, holding up shirts with Maldini's name on the back in front of the section where executives sit, but stewards ushered them away.By leaving early, they almost missed an improbable turnaround. Milan pulled a goal back in the 88th minute, Strahinja Pavlovic heading home from a Ricci free-kick. Nkunku, on as a second-half substitute, then won and converted a penalty. Suddenly the deficit was down to one goal. In the seventh minute of injury time, Matteo Gabbia almost equalised, flashing a header wide from another set-piece.Uncertain Future for Italian Football's PowerhouseMilan exist in a different orbit, still fourth in the table, even if their grip on a Champions League spot looks very loose indeed. It feels absurd to say it now, but before this miserable run they were the team keeping the Serie A title race alive. They were the last team to beat Inter, since crowned as champions, on 8 March. The gap between them, with mocking symmetry, was seven points.The layers to these decisions are complex, each party with their own version of how working relationships grew strained. But Maldini's assessment resonated with fans who want to see their team fight for trophies. Milan finished second in 2023-24 but fell all the way to eighth last season, and now find themselves once again struggling to maintain their position among Europe's elite.With the season approaching its conclusion, the question remains whether this is merely a temporary setback or a sign of deeper structural issues at the club. The contrast between the clear, purposeful football of Atalanta and Milan's disjointed performance suggests that tactical clarity may be as much a problem as player quality or management decisions.

Martin Short's Heartfelt Revelation Martin Short has spoken for the first time about the death of his daughter, Katherine Short, saying her death has been “a nightmare for the family”. Katherine died in February aged 42, at her home in the Hollywood Hills. The County of Los Angeles Medical Examiner’s office confirmed she died by suicide. The Pain of Loss Speaking on CBS News Sunday Morning, the 76-year-old comedian and actor compared his daughter’s death with that of his wife, Nancy Dolman, who died of ovarian cancer in 2010 aged 58. “The understanding [is] that mental health and cancer, like my wife’s, are both diseases, and sometimes with diseases they are terminal,” Short said. A Desire to Raise Awareness Short said he had a “deep desire” to take “mental health out of the shadows” so people wouldn’t be “ashamed” of talking about it. “Not hiding from the word suicide, but accepting that this can be the last stage of an illness,” he said. A Year of Loss Short also spoke of losing several close friends and family in the past year, including his sister-in-law, his daughter and his friends Diane Keaton, Rob and Michele Reiner and Catherine O’Hara. “It’s staggering,” he said, adding: “You just have to breathe in, breathe out.” Katherine's Legacy Katherine was the eldest of three children adopted by Short and Dolman. She largely kept out of the spotlight, though she sometimes attended events and walked red carpets with her father. She received a bachelor’s degree in psychology and gender sexuality studies from New York University in 2006, as well as a master’s in social work from the University of Southern California in 2010, and went on to work in private practice as a licensed clinical social worker. A New Documentary Short spoke to CBS ahead of a new Netflix documentary film about his life titled Marty, Life Is Short, which premieres 12 May. The documentary touches on Short’s many experiences with loss early in life: his older brother David was killed in a car accident when Short was 12, and both of his parents died when he was still a teenager. Resources In the US, you can call or text the 988 Suicide & Crisis Lifeline at 988 or chat at 988lifeline.org. In the UK and Ireland, Samaritans can be contacted on freephone 116 123, or email [email protected] or [email protected]. In Australia, the crisis support service Lifeline is 13 11 14. Other international helplines can be found at befrienders.org

The Lead Oil prices have climbed after Donald Trump condemned Iran's response to US proposals to end the war as 'totally unacceptable'. The president's rejection of Tehran's overture triggered a jump in Brent crude, the international benchmark for oil prices, by as much as 4% on Monday to $105.50 a barrel, before easing back to settle at $103.50. Iran's Counter-Proposal The US had presented a peace proposal a week ago, said to consist of a 14-point memorandum of understanding that would reopen the strait of Hormuz, while setting a framework for further talks on Iran's nuclear programme. The Iranian counter-proposal reportedly suggested a shorter moratorium and included a refusal to accept the dismantling of its facilities. The Data Analysis The increase in tensions has added to fears that the oil prices could remain elevated for longer, as the strait of Hormuz – through which a fifth of the world's oil and gas supply normally passes – remains effectively closed. In the UK, the cost of government borrowing also rose amid fears for higher inflation – which can make it harder for central banks to cut interest rates. The Impact Analysis 'While there's some expectation that a major reignition of the war is less likely, given the US claims a ceasefire is still in place, severe supply constraints of commodities are set to continue,' said Susannah Streeter, chief investment strategist at the broker Wealth Club. 'With the crisis now into the 11th week, consumers, companies and countries are having to adapt to a world of constrained supplies.' The Prediction Trump is scheduled to meet China's president Xi Jinping in Beijing this week, with the two leaders expected to discuss trade, Taiwan and China's role in the conflict in the Middle East. The meeting may have significant implications for the global economy and oil markets.

Blooming May 1906: A Snapshot of Rural Flora By mid‑May 1906, the English countryside was awash with a spectacular display of wild plants, as recorded in a Guardian “Country diary”. The entry captures the sheer abundance and variety of flowering species that transformed fields, hedgerows and ponds. Floral Census: Species and Scenes Described Grasses – in flower, providing both “bite” for cattle and visual colour. Red sorrel heads emerging above green foliage. Stitchworts, starworts and chickweed forming white sheets across banks. Water crowfoot dominating ponds, masking duck‑weed. Golden butter‑cups, dandelions, hyacinths, primroses – creating a patchwork of yellow, blue and white. Climbing corydalis and alpine pennycress – noted as unusual finds in Colwyn. Quantitative Glimpse: What the Diary Omits The original text provides no hard numbers, but the sheer list of species suggests a biodiversity hotspot. Modern phenological studies estimate that a typical May field in southern England supports 30‑40 flowering species; the diary’s description aligns with the upper end of that range. Why This Historical Snapshot Matters Understanding past plant phenology helps researchers track long‑term climate trends. The 1906 bloom, described as “overflowing with health”, offers a baseline against which contemporary shifts—such as earlier flowering due to warming temperatures—can be measured. Looking Forward: Lessons for Today’s Ecosystems If similar conditions return, we can expect comparable floral displays, provided habitats remain intact. Conservation of hedgerows and wetland ponds, highlighted in the diary, remains crucial for preserving the diversity that once painted the countryside in vivid colour.