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Riki Lindhome's 'Dead Inside' is a refreshing and emotionally involving comedy that chronicles her journey to become a mother. The show is a beautifully judged hour of entertainment, tackling topics such as pregnancy loss, IVF, and surrogacy with humor and sensitivity.Lindhome's modesty and unassuming approach make the show feel less like a typical autobiographical performance. She signs off most of her songs with a demure 'that's it,' and the production values are similarly understated. The show features witty and bittersweet numbers, including a parody of Disney princesses and a song asking 'will you be my bio-dad?'The show also touches on awareness-raising dimensions, including the challenges of surrogacy and the importance of transparency in the process. Lindhome's performance is compelling and persuasive, engaging the audience's heart, head, and funny bone.'Dead Inside' is a must-see comedy that will leave you entertained and moved. It is currently running at Soho theatre, London until 18 April.

Scientists at London's Institute of Cancer Research and the RCSI University of Medicine and Health Sciences in Dublin have announced a new AI-driven approach to identify how patients with advanced bowel cancer will respond to bevacizumab, a drug recently introduced by the NHS. The method uses PhenMap, an AI tool that integrates complex data on the genetic makeup of tumors, allowing researchers to track patterns of how different patients react to the drug. This development aims to spare potentially thousands of patients from being given drugs that would be ineffective in fighting their cancers. In the UK alone, nearly 10,000 cases of advanced bowel cancer are identified every year, with young adults seeing a particular rise in diagnoses. Bowel cancer has the second-highest mortality rate of any cancer, behind only lung cancer. While survival rates can be as high as 98% when caught early, the five-year survival rate for advanced bowel cancer can be as low as 10%. The study tracked 117 European bowel cancer patients who had been treated with chemotherapy and bevacizumab. Researchers identified a group of patients who all had the same gene mutation and were at a high risk of having negative reactions. The scientists behind the tests now hope to expand the number of patient samples and see if the results can be used in treatments for other types of cancer. Anguraj Sadanandam, a professor in stratification and precision medicine at the ICR, said: “Once bowel cancer spreads to other parts of the body, there are very few treatment options available for patients. It is therefore positive that patients can now access the targeted drug bevacizumab on the NHS. However, we know that the majority of patients won’t benefit from the drug, meaning thousands of people in England could be facing unpleasant side effects unnecessarily.” Sadanandam added that while the findings were encouraging, the tool would need to be tested on a larger cohort to be validated. “In future, I hope this approach will lead to a test that can be used by clinicians, to ensure patients receive personalised care that has the highest chance of working against their cancer.”

At the break of day in Keswick, the air still carries a chill despite it being April. From a drystone wall on St John’s Vale, I watched the sky race past Helvellyn, while bright daffodils bowed on a nearby farm as if shivering in the breeze. The surrounding trees stood still, and a shaft of sunlight ignited the bracken below the crags, turning it a vivid colour that starkly contrasted with the dead grass and dark scree. This scene illustrates a place where change has settled gently, with farms preserving their protective belts of trees that nestle comfortably against the fell’s edge.The low fields echoed with the call of curlews, and although some farmers elsewhere lament a lack of moisture, the land here was saturated; the river ran brown with flood‑water and the becks churned white. Many ewes were gathered for lambing, yet one independent ewe chose to give birth alone on a small green shelf in a ghyll above a stream. The newborn lamb was still damp and trembling when a farmhand arrived in his tractor, loading the pair onto a hay‑lined trailer to bring them back to the safety of the farm, fearing the lamb might tumble into the beck as its mother went to drink.

Asha Bhosle, the iconic voice of Bollywood for over seven decades, has died at age 92 in Mumbai, according to her family. The two‑time Grammy nominee passed away on Sunday at Breach Candy Hospital, where she had been admitted for "extreme exhaustion" and a chest infection. Her son, Anand Bhosle, confirmed the news to reporters, stating, "My mother passed away today. Her last rites will be held tomorrow at Shivaji Park in Mumbai." Throughout her prolific career, Bhosle recorded more than 12,000 songs in multiple Indian languages, shaping the soundscape of Bollywood cinema from the 1970s through the 1980s and beyond. Prime Minister Narendra Modi expressed his sorrow, describing himself as "deeply saddened" by the loss of a cultural legend whose music resonated across generations. The nation now prepares to bid farewell to a figure whose contributions to Indian music remain unparalleled, with funeral services set for Shivaji Park, a venue symbolic of her enduring legacy.

A heartfelt tribute has been paid to Dame Jenni Murray, a renowned figure in British radio, known for her exceptional broadcasting skills and generosity of spirit. The author recalls her kindness and guidance when they appeared as a guest on Woman's Hour in the 1990s, discussing their novels on topics such as motherhood and dieting. Dame Jenni shared valuable insights into the art of radio broadcasting, including the importance of not discussing the main topic in the green room to save the best lines for the show. She also emphasized the need to turn off mobile phones before entering the studio, a lesson she occasionally forgot herself, much to the frustration of her producers. Her warm and approachable nature made her a beloved figure, both on and off the air. The author fondly remembers her staying on for a glass of wine in the BBC canteen after shows and her remarkable charity work, particularly with the Young Oncology Unit at the Christie hospital in Manchester. Dame Jenni's infectious humor and big-heartedness inspired others to get involved in charitable initiatives, leading to successful fundraising dinners and a significant impact on the community.

GSK has revealed promising early results for its treatment for gynaecological cancers, Mocertatug Rezetecan (Mo-Rez), as its chief executive, Luke Miels, seeks to speed up drug development at the group.The company reported that in an early-stage trial, Mo-Rez shrank or eliminated tumours in 62% of patients with ovarian cancer where chemotherapy had failed, and in 67% of those with endometrial cancer.GSK acquired the Mo-Rez cancer treatment, an antibody-drug conjugate (ADC), from China’s Hansoh Pharma in late 2023, and has trialled it in 224 patients around the world, including the UK, over the past year. Few patients needed to stop treatment because of side-effects, the most common being nausea. It is administered every three weeks via intravenous infusion.Combined with data from a separate, intermediate trial in China, these results give GSK the confidence to go straight to late-stage trials, with five clinical studies planned globally in the next few months, including on patients in the UK.Presenting the results at the Society of Gynecologic Oncology’s annual meeting on women’s cancer in Puerto Rico, Hesham Abdullah, GSK’s global head of cancer research and development, said: “Treatment of gynaecological cancers remains a major challenge, with a pressing need for new therapies that offer improved response rates. With Mo-Rez we now have compelling evidence of a promising clinical profile.”Endometrial cancer affects 1.6 million women globally, with 417,000 new cases each year. Ovarian cancer affects 843,000 people, with 240,000 new cases annually.Abdullah described Mo-Rez as a “key asset” in the company’s growing cancer portfolio, expected to be a blockbuster drug with peak annual sales of more than £2bn, which GSK hopes will help it achieve its 2031 sales target of £40bn.

Springtime in a typical British suburb is a chorus of birds, buzzing insects and the occasional rumble of a mini‑digger. While sparrows spar and tits clash over territory, a crew of contractors is often busy erasing hedges, bushes and trees, leaving behind a stark trench of bare earth. In one April afternoon, a once‑lush front garden was reduced to a skip full of uprooted branches and a strip of exposed soil. Despite the nation’s reputation as a garden‑loving society, the trend toward concrete is accelerating. An RHS audit published last year found that 42% of domestic garden space in the United Kingdom has been paved over, with timber fences replacing wild privet and driveways smothering mossy lawns. The loss is not merely aesthetic; it erodes habitats that support a remarkable share of the country’s wildlife. According to the Royal Horticultural Society, over 50% of Britain’s butterflies, amphibians and reptiles, and more than 40% of its bird and mammal species rely on garden habitats. The new David Attenborough series Secret Garden underscores this, describing urban gardens as “almost as diverse as a tropical rainforest.” Yet, as the series aired, another garden was being stripped to the ground, highlighting the tension between media‑driven reverence and on‑the‑ground reality. Socio‑economic factors compound the issue. One in eight households in the UK has no garden at all, and lower‑income families and ethnic minorities are disproportionately deprived of green space. Even owners of gardens often lack the time, money, or confidence to cultivate biodiverse oases, viewing gardening as a burdensome chore. Experts suggest a radical, yet simple, alternative: do nothing. Allowing dandelions, thistles, and stray grasses to flourish provides nectar for pollinators, while bare patches become nesting sites for bees and birds. Unraked leaves serve as winter shelters for insects, and dead stalks become food for aphids, which in turn feed higher‑up predators. The “negative space” of an untended garden can therefore become a hotbed of ecological activity. Conservationists argue that embracing this messiness could reverse the decline of urban biodiversity. As one commentator mused, “If Sir David Attenborough could return for a bonus episode, he might show us that a tangled, overgrown garden is not a failure but a vibrant ecosystem in its own right.” By Emma Beddington, 12 April 2026

Asha Bhosle, the iconic voice of Bollywood, passed away at age 92 after being hospitalized in Mumbai with severe exhaustion and a chest infection, her family confirmed.Her son, Anand Bhosle, told reporters that his mother died on Sunday and that her last rites would be performed the following day at Shivaji Park in Mumbai.Over a career that stretched across nearly eight decades, Bhosle recorded more than 12,000 songs, pioneering cabaret and Western‑influenced styles that broadened the sonic palette of Indian cinema.India’s Prime Minister Narendra Modi expressed deep sorrow, noting that her "extraordinary musical journey" enriched the nation’s cultural heritage and will continue to inspire future generations.Born on 8 September 1933 into a musical family, she was the younger sister of the celebrated vocalist Lata Mangeshkar, often referred to as “India’s nightingale.” While comparisons were inevitable, Bhosle forged a distinct path, embracing genres from pop to folk.Her early years were marked by hardship, including a turbulent marriage at the age of 16, yet she rose to become one of Indian cinema’s most versatile singers, earning the prestigious Dadasaheb Phalke Award in 2000 and receiving two Grammy nominations.Even in her later years, Bhosle remained artistically active, collaborating with the British virtual band Gorillaz on their album The Mountain, demonstrating her enduring global appeal.Beyond music, she pursued a passion for cuisine, establishing the Asha’s restaurant chain in Dubai and the United Kingdom, further cementing her status as a cultural entrepreneur.Agence France‑Presse and Associated Press contributed to this report.

Celtic overtook rivals Rangers to sit second in the Scottish Premiership after a narrow 1‑0 win against St Mirren, while Hearts preserved their lead at the top with a late‑filled 3‑1 triumph over Motherwell.At Celtic Park, Alex Oxlade‑Chamberlain broke the deadlock in the 15th minute. After a blocked attempt from Benjamin Nygren, Kieran Tierney delivered a precise cross that Oxlade‑Chamberlain struck into the bottom corner, giving Celtic a comfortable first‑half advantage.St Mirren dominated possession in the second half but failed to create clear chances, allowing Celtic to hold onto the solitary goal.The encounter marked the first meeting between the sides since St Mirren’s surprise 3‑1 cup win over Celtic in December, a result that proved difficult to repeat.For the first time since November, the Green Brigade were welcomed back to Celtic Park, adding a vibrant backdrop to what many view as a dress rehearsal for next week’s Scottish Cup semi‑final.At Tynecastle, Motherwell took an early lead through Emmanuel Longelo. Hearts responded quickly when Cláudio Braga equalised with an overhead kick. The match seemed poised for a draw until Lawrence Shankland converted a penalty after Stephen Welsh was judged to have fouled Landry Kaboré. Kaboré then added a third in stoppage time, sealing the three‑point win for Hearts.In the north, Stephen Robinson ended his winless streak since moving from St Mirren to Aberdeen, guiding his side to a 2‑0 victory over Hibernian at Pittodrie, with Kevin Nisbet scoring in each half.At Tannadice, Zac Sapsford rescued Dundee United with a late penalty, completing a dramatic 3‑2 comeback against Livingston. The hosts had led through a first‑half goal by Will Ferry, but Livingston responded with a quickfire double from Lewis Smith before United equalised via substitute Krisztian Keresztes.Meanwhile, Kelle Roos produced a crucial stoppage‑time penalty save against Dundee striker Joe Westley, earning Kilmarnock a vital point in their relegation battle. The decision followed a lengthy VAR check that delayed the penalty by six minutes.Kilmarnock’s earlier clash with Dundee saw a roller‑coaster finish: Joe Hugill opened the scoring, Simon Murray equalised for Dundee, Michael Schjønning‑Larsen restored the lead for Kilmarnock before Scott Wright’s late goal forced extra‑time drama.