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The Breakthrough in Addiction Treatment Results from a new clinical trial published in JAMA Network Open this month show that a single dose of psilocybin could be an effective treatment for cocaine addiction. The study found that 19 participants who received psilocybin were more likely to abstain from cocaine than 17 participants who received a placebo of diphenhydramine, a common antihistamine. Participants in both groups worked with therapists to process their experiences, highlighting the importance of the therapeutic context alongside the medication. The Urgent Need for Cocaine Addiction Treatments Dr. Peter Hendricks, a behavioral health professor at the University of Alabama at Birmingham and lead author of the study, emphasized the critical need for effective treatments. Currently, there are no FDA-approved medications for addiction to cocaine or other stimulants like methamphetamine. Overdoses involving stimulants are killing more Americans, and according to the latest UN global drug report, cocaine deaths are rising globally as cocaine production reaches an all-time high. Understanding the Mechanism Experts believe psilocybin works by increasing neuroplasticity and psychological plasticity – the ability to change thinking and behavior. Addictions inherently involve resistance to changing rigid, impulsive behaviors, which psychedelics may help overcome. Unlike traditional addiction medications that target the same neurochemical systems as the substance itself, psilocybin produces a profound altered state of consciousness within a structured psychotherapy context. It acts more like a catalyst within a therapeutic process rather than a maintenance medication. Addressing Cocaine Withdrawal Symptoms Cocaine withdrawal symptoms are primarily psychological rather than physically painful, including bad dreams, agitation, depression, and cravings. This psychological nature may make psilocybin particularly effective for cocaine addiction, as it can facilitate shifts in perspective and self-compassion that help people change their behavior. The therapeutic framework allows individuals to process their experiences and develop new insights about their addiction patterns, potentially breaking the cycle of craving and use. Diverse Clinical Trial Participation This study is notable as the first psychedelic clinical trial to include a majority of Black participants. While many spiritual rituals involving psychedelics originated in Indigenous societies in Latin America and Africa, US psychedelic culture today is often associated with Silicon Valley and elite, white personalities. Dr. Hendricks specifically recruited participants who were dependent on cocaine and wanted to stop, rather than advertising for psychedelic enthusiasts. This approach likely reduced the "expectation effect" and produced more generalizable results. Future Research Directions A critical commentary published alongside the study noted that the results might not be generally applicable because the study excluded people with comorbid depression and anxiety. However, experts point out that psilocybin shows promise for treating both conditions. The success of this trial is a clear indication that psilocybin for cocaine use disorder is a promising treatment that should proceed to larger-scale clinical trials. As research continues, the medical community may gain more insight into how psychedelics can be integrated into addiction treatment protocols.

Lead: A Ouija‑Board Dialogue with the CanvasSanya Kantarovsky describes his process as “like a Ouija board, I listen to the painting,” a sentiment that permeates his latest exhibition, Basic Failure, which opened in May 2026 at Venice’s Institute of Sciences, Letters and Arts. The show, timed with the 2026 Biennale, confronts viewers with dishevelled figures, uncanny transformations and a lingering sense of alienation. Basic Failure Opens in a Historic Venetian PalazzoSet within a palazzo of high ceilings, dark terrazzo‑marbled floors and walls lined with antique books, the exhibition begins with the diminutive portrait Boy With Cigarette. The painting’s pallid, down‑turned youth, rendered in thick blue brushstrokes, “feels both familiar and kind of alien at the same time,” according to the artist. Nearby, a child spins carefree, creating a visual tension between innocence and menace. Quantifying the Exhibition: Scale and ReachOpening date: May 2026Artist age: 44Venue capacity: approximately 200 visitors per hour during peak Biennale daysNumber of works displayed: over 30 paintings and installations Impact: Re‑defining the Supernatural in Contemporary ArtKantarovsky’s work draws on Russian literary darkness while echoing the metaphysical concerns of Pablo Picasso, Giorgio de Chirico and Milton Avery. By rendering subjects from memory rather than direct observation, he creates “narrative fragments” that challenge conventional storytelling in visual art. The exhibition’s dialogue with religious iconography—referencing Masaccio’s expulsion of Adam and Eve—adds a layer of cultural critique that resonates with the Biennale’s broader exploration of identity and displacement. Looking Ahead: The Future of Narrative FragmentationKantarovsky predicts that his “basic failure” methodology—embracing the inability to fully translate internal visions—will inspire a new wave of artists to explore the unconscious through fragmented, non‑linear imagery. As the Biennale draws global attention, the show is poised to cement his reputation as a provocateur who bridges psycho‑analysis and contemporary painting.

Utah Lawmakers Unite to Target Prediction MarketsRepublican leaders in Utah have formed a coordinated front to outlaw prediction‑market apps, arguing they are merely “gambling – pure and simple.” Governor Spencer Cox and state senator Brady Brammer pledged to use every state resource to block platforms such as Kalshi and Polymarket, even as the federal government under the Trump administration defends the sector.Legislative Push Expands State Gambling DefinitionIn March 2026 the GOP‑controlled Utah legislature passed a constitutional amendment that broadens the legal definition of gambling to include “proposition bets,” a term that covers bets on any individual action, statistic, occurrence or non‑occurrence. Governor Cox signed the measure, ensuring that prediction‑market contracts fall squarely under Utah’s anti‑gambling statutes.Bill HB0243 – adds “proposition bets” to the state’s gambling ban.February 2026 – Kalshi files a lawsuit alleging Utah’s actions violate federal CFTC jurisdiction.Attorney General Derek Brown – publicly declared prediction markets are “a bet dressed up in different clothing.”Valuation and Legal Landscape of Prediction Market PlatformsPrediction‑market platforms have surged in popularity and value. Kalshi is recently valued at $22 bn, while the industry faces roughly 20 federal lawsuits across the United States. Court outcomes have been mixed: a federal judge blocked criminal charges in Arizona, but Nevada and Tennessee have issued injunctions against the same platforms.$22 bn – Kalshi’s latest valuation.~20 federal lawsuits – nationwide legal pressure on prediction‑market firms.Mixed rulings – victories in Arizona, setbacks in Nevada and Tennessee.Implications for State vs Federal Regulation of Digital BettingThe Utah effort highlights a growing clash between state anti‑gambling laws and the Commodity Futures Trading Commission’s (CFTC) claim of exclusive jurisdiction over prediction markets as financial derivatives. While the Biden administration sought to restrict election‑related contracts, the Trump administration reversed course, reinforcing the CFTC’s authority. Utah’s challenge could force courts to clarify whether state gambling statutes can preempt federal commodities law.Potential Outcomes and National Legal Battles AheadLegal experts anticipate several possible trajectories: (1) federal courts may reaffirm CFTC jurisdiction, limiting Utah’s ability to enforce its ban; (2) the U.S. Supreme Court could take up the state‑federal conflict, setting a nationwide precedent; or (3) a compromise regulatory framework could emerge, allowing states to impose consumer‑protection measures while preserving the platforms’ derivative status. In any case, Utah’s aggressive stance is likely to influence other conservative states considering similar bans.

The Lead: US-Nigeria Joint Military Operation Against ISILThe United States military's Africa Command (AFRICOM) has conducted additional air strikes against ISIL (ISIS) fighters in northeastern Nigeria in coordination with the Nigerian government. These "additional kinetic" strikes, which took place on Sunday and were announced on Monday, represent the latest in a series of collaborative military operations between the two nations targeting terrorist groups in the region.The Event Details: Recent Strikes and Leadership DecapitationThe latest strikes occurred two days after both countries' presidents announced the killing of Abu-Bilal al-Minuki, described as the second in command of ISIL. Al-Minuki was targeted "along with several of his lieutenants" in a strike on his compound in the Lake Chad Basin, Nigerian President Bola Tinubu confirmed on Saturday. US President Donald Trump first made the announcement in a social media post on Friday without disclosing specific details about the operation.Before pledging allegiance to ISIL in 2015, al-Minuki was a prominent Boko Haram leader, according to the Nigerian army. He oversaw key ISIL operations in the Sahel and West African regions for the ISIL affiliate in West Africa Province (ISWAP).The Strategic Context: Expanding US Military Presence in NigeriaThis latest wave of US-Nigeria coordinated attacks comes as dozens of US soldiers have been deployed to Nigeria in recent months to help fight against armed groups, engage in intelligence sharing, and provide technical support. Nigeria's Defence Headquarters spokesman Samaila Uba clarified that US soldiers will not play a direct combat role but will share technical expertise under the full command authority of Nigerian forces."The removal of these terrorists diminishes the group's capacity to plan attacks that threaten the safety and security of the US and our partners," AFRICOM stated in its announcement. "AFRICOM remains committed to leveraging specialized US capabilities in support of our partners to defeat shared security threats."The Regional Impact: Power Vacuum and Shifting AlliancesDennis Amachree, former director of the US Department of State Services in Nigeria, told Al Jazeera that the killing of al-Minuki "is going to create a huge vacuum in the leadership and financing of ISWAP as many top officers were decimated with him." This assessment suggests that the targeted strikes may have a more significant impact than initially apparent, potentially disrupting the operational capabilities of ISWAP in the region.The Nigerian government has previously rejected Trump's accusation of mass killings of Christians in the country, with analysts noting that people across all faiths, not just Christians, are victims of armed groups. This context highlights the complex nature of the security challenges in Nigeria and the broader Sahel region.The Future Outlook: Escalating Counterterrorism OperationsLast Christmas, US forces launched air strikes on ISIL-affiliated fighters in northwestern Nigeria. When asked if this was part of a broader military campaign, Trump told The New York Times: "I'd love to make it a one-time strike. But if they continue to kill Christians, it will be a many-time strike." This statement suggests a potential escalation in US military involvement in the region, contingent on perceived threats.As the US continues to expand its counterterrorism operations in West Africa, the coordination with regional partners like Nigeria will be crucial. The success of these operations in degrading terrorist capabilities while maintaining local sovereignty will likely shape future security partnerships in the region.

Lead: Einstürzende Neubauten’s New Chapter in 2026The legendary Berlin outfit Einstürzende Neubauten closed the 15th Rewire festival with a surprise announcement: bassist Josefine Lukschy joins the band, marking the first personnel change since 1997. Frontman Blixa Bargeld assured fans that the group will continue recording, dispelling rumours that the 2024 album Rampen might be their swan song.Band Milestone: Adding Bassist Josefine Lukschy After Four DecadesAfter Alexander Hacke announced his exit in April 2025, the band conducted a discreet audition process, ultimately selecting Lukschy, a Berlin‑based musician known for the sludge‑rock project Crashpad. Their public introduction came in late March 2026, a year after Hacke’s departure. The new lineup debuted on stage at the Rewire festival, complete with the band’s signature tools—shopping trolleys, pipes, and metal sheets.Numbers that Frame the Journey1980: Band founded in West Berlin.1997: Last major lineup expansion (Jochen Arbeit, Rudolph Moser).2022: Live improvisations later used as foundations for Rampen.2024: Release of Rampen, the latest studio record.2025: Hacke’s departure after 45 years with the group.2026: Lukschy becomes the first non‑male member since the early co‑founders.Why This Matters for Berlin’s Cultural LandscapeThe addition of Lukschy reflects a broader shift in Berlin’s artistic scene, which has been grappling with budget cuts and debates over its global status. As a band that helped define the city’s industrial sound—later influencing acts like Nine Inch Nails and Swans—their evolution mirrors Berlin’s own transition from post‑war DIY rebellion to an established cultural institution. Bargeld’s recent Order of Merit underscores the band’s integration into the national cultural fabric, while Lukschy’s presence signals a new, more inclusive generation.Looking Ahead: What’s Next for the Iconic Industrial Pioneers?With a refreshed lineup, the group has hinted at a new record that will build on the improvised material from their 2022 shows. Fans can expect further festival appearances across Europe in 2026‑27, and potentially a collaborative project that blends Lukschy’s sludge‑rock sensibilities with the band’s signature metal‑scrap sound. Their continued relevance may also inspire a resurgence of experimental venues in Berlin, reinforcing the city’s reputation as a haven for avant‑garde music.

Opening the Silent Corridors of Cork’s AsylumThe Guardian’s latest review spotlights *Said the Dead*, a meticulously researched yet poetically daring study of the Cork Mental Hospital – once Ireland’s longest Gothic building, shuttered in the 1990s and now being turned into apartments. Doireann Ní Ghríofa uses the archive as a portal, giving voice to women whose stories were consigned to dusty casebooks.How Doireann Ní Ghríofa Reconstructed 19th‑Century Patient LivesWorking primarily from the hospital’s massive green casebooks, the author is forced to stop a century before the present to respect confidentiality, so the narrative centers on Victorian and Edwardian voices. She extracts vivid portraits – Bridget, a pregnant emigrant turned back home; Anna Martha, a painter who brandished a gun on magistrates; Dora, a sixteen‑year‑old yearning for death; and Muriel, wife of republican lord mayor Terence MacSwiney. The book also foregrounds Lucia Strangman, the first woman psychiatrist in the British Isles, as a thematic double for the author‑reader.Archive constraint: records stop at a 100‑year distance.Key patients: Bridget, Anna Martha, Dora, Muriel.Medical language: “fairies work on her nerves”, “dull”, “intelligent”.Why Revisiting the Asylum Matters for Irish Memory and Mental‑Health DiscourseThe review argues that the book does more than recount forgotten biographies; it interrogates the ethics of reading and surveillance. By positioning herself as “the Reader”, Ní Ghríofa acknowledges the power imbalance inherent in extracting lives from institutional records, echoing contemporary debates on mental‑health stigma and historical accountability. The work thus becomes a catalyst for broader conversations about how societies remember—and often erase—marginalised voices.What This Revival Signals for Historical Narrative and Public EngagementAs the former asylum is repurposed into luxury flats, *Said the Dead* reminds readers that commercial redevelopment can obscure painful histories. The book’s blend of scholarship and imagination may inspire similar projects that rescue silenced narratives, encouraging museums, publishers, and educators to foreground archival voices before they disappear beneath modern façades.

Opening Verdict: Spall’s Playful Return Powers Death ValleyThe latest season of Death Valley proves that a seasoned actor can turn a modest, self‑referential mystery into pure entertainment. Timothy Spall embraces the role of John Chapel with a breezy confidence that lifts the series above its deliberately simple plotting.Season Two’s Premise and Character ShiftsReturning to the Welsh valley, the show leans further into its show‑within‑a‑show conceit. Key developments include:Janie Mallowan (Gwyneth Keyworth) promoted to detective inspector, still affectionately called “J‑Dog”.John Chapel now openly courting Janie’s mother, Vonnie, sparking workplace tension.Cases range from a litter‑picking crew death to the murder of a hipster street‑food chef, each resolved with deliberately stagey deductions.The series balances absurdity with warmth, relying on guest cameos such as Alexandra Roach and Jim Howick to accentuate its cosy tone.Audience Reception and Broadcast DetailsWhile concrete viewership numbers have not been disclosed, the series is:Broadcast on BBC One.Available on BBC iPlayer in the UK.Streaming on BritBox in Australia.Critical response highlights Spall’s chemistry with Keyworth as the primary draw, noting the show’s intentional lightness as a virtue rather than a flaw.Why Cosy Crime Still Resonates in 2026In an era dominated by gritty procedurals, Death Valley offers a counter‑point: low stakes, predictable rhythms, and a focus on character rapport. Its meta‑commentary on television tropes—characters calling out “banality” and “hammy” performances—creates a self‑aware humor that appeals to viewers fatigued by relentless tension.Future Outlook for Death Valley and the Cosy Crime GenreIf the series maintains its current formula, it is likely to secure a niche audience that values comfort over complexity. Continued involvement from high‑profile talent like Spall could attract occasional viewers, while the show’s modest production values keep it financially sustainable for the BBC. The cosy crime niche appears set to thrive as a reliable alternative to more intense dramas.

The Wedding TragedyDrone strikes by Mali's army have killed at least 10 civilians as they prepared to celebrate a wedding in the central region of San, marking another escalation in the conflict since armed groups launched a widespread coordinated assault late last month. The strikes on Sunday occurred during a security crisis after attacks on the military government's positions last month by fighters from the al-Qaeda-linked Jama'at Nusrat al-Islam wal-Muslimin (JNIM) and Tuareg separatists known as the Azawad Liberation Front (FLA).A resident of the Tene locality, where the strikes took place, told the AFP news agency that "10 of our children" were killed. "What was supposed to be a moment of joy in the village turned into immense sorrow," he said, speaking on condition of anonymity. "The tragedy occurred as the villagers were preparing the second edition of this traditional collective wedding, a major cultural event for this community," a security source who requested anonymity for safety reasons told AFP.The Escalating ConflictMali has been in a critical security situation since JNIM teamed up with rebels in the FLA in April. A deadly offensive on April 25 and 26 targeted strategic towns and killed the country's influential defence minister. Kidal and other towns and villages in the north have been captured and are now controlled by the FLA and JNIM, who have since imposed a blockade on the capital, Bamako.Another wave of attacks by al-Qaeda-affiliated fighters was also reported on May 7, killing at least 30 people in central Mali. The villages of Korikori and Gomossogou in the Mopti region were targeted. Mali, which is rich in gold and other valuable minerals, has been dealing with unrest since 2012. It has faced a deepening security crisis driven by the FLA, JNIM and the Africa Corps, a Russian government-controlled paramilitary that replaced the private Wagner Group.International InvolvementMali's former colonial ruler, France, and the United Nations had deployed soldiers and peacekeepers to the country to try to control the violence by armed groups, but Bamako expelled their forces after military coups in 2020 and 2021 and is now using Russian fighters instead. Al Jazeera's Nicolas Haque, who has reported extensively from Mali, had said, according to military sources, "the fighters involved in this coordinated attack are targeting military armed compounds", adding that "there is an unprecedented level of panic" in the military ranks.Haque told Al Jazeera he learned from witnesses that Russian mercenaries were "fighting in Bamako, around the airport, where they have one of their headquarters". Alex Vines, Africa director at the European Council on Foreign Relations, told Al Jazeera that Malian authorities appear to have been caught off guard by the latest wave of attacks.

The Weekend's Football Action: Key Talking PointsThe latest round of Premier League matches and the FA Cup final provided plenty of talking points for football fans, from Manchester City's cup triumph to Liverpool's injury concerns and the ongoing VAR controversies that continue to divide opinion.Shaw's World Cup Hopes After Impressive SeasonLuke Shaw's first goal in over three years for Manchester United was a further reminder of the left-back's capabilities. This has been his best season at Old Trafford having featured in all 37 league games thus far, leaving his injury-prone past forgotten. Considering Shaw's experience and quality, he should be considered for a spot at the World Cup. Thomas Tuchel does not have a vast array of riches in the position and Shaw's consistency has been key to Michael Carrick's turnaround at Old Trafford. "He deserves to go," said Carrick after the win against Nottingham Forest. "His consistency, his performances, his experience, his qualities. He's an excellent full-back." Nico O'Reilly is the current first choice for England and he has a very different profile from Shaw, having converted from playing as a central midfielder under Pep Guardiola. Tuchel may want to take Shaw to provide variety and reliability, which would be a sensible approach.VAR Controversy Continues to Plague the GameAnother weekend of football brought another VAR controversy, this time at Old Trafford. Let's get this out of the way, it was handball. In a game with more on the line this latest VAR aberration would be hoisted up by abolitionists as another egregious example of why football is no better for the involvement of Stockley Park. "I think we need to have a meeting together to understand when it is a handball," said a measured Vítor Pereira post-match. We need a meeting to understand what good process is. Accidental handball was the final ruling; not sure that matters when it leads to a goal, but whatever. From the original incorrect decision to award the goal, it took the VAR three minutes to look at the ball clearly striking Bryan Mbeumo's hand, then another 60 seconds for the referee, Michael Salisbury, to go over to the screen and look at it again, only to ignore the referral and decide he was right the first time. That is far too long to make the wrong call. Pereira neatly summed it up with another damning understatement: "A lot of the time we don't understand the decisions."West Ham's Fight Against RelegationWhile it was hard to argue with Nuno Espírito Santo's assessment that West Ham had "a bad performance and a bad day" at St James' Park, his team are not Championship-bound just yet. Tottenham only need a point against Chelsea on Tuesday to effectively ensure their survival owing to their far superior goal difference, but they last took a point at Stamford Bridge four years ago. Their record against Chelsea is not reassuring: they have lost their past five meetings on the bounce by an aggregate scoreline of 12-4, with eight defeats from their last 10. Chelsea's players will have the added motivation of auditioning for the newly appointed Xabi Alonso, not that they need another reason to make their opponents' lives miserable. It could still easily come down to the final day, when Spurs face another difficult fixture against Everton. Nuno can only grit his teeth, hope Chelsea do his side a favour and, assuming Spurs's horrible run in west London continues, rally his troops for a desperate last stand against Leeds.Liverpool's Injury Woes ContinueAston Villa's season high represented another sobering low for Liverpool. Arne Slot's side failed to hurt Villa and were weak in defence, leaking two more goals at set pieces. Liverpool were without nine first-team players, including Alexander Isak, their £125m marquee signing who was not risked with a minor problem but could return against Brentford on the last day. Isak's season has been symptomatic of Liverpool's struggles. Is it just bad fortune or have Slot and his side simply underperformed? The truth is probably somewhere in the middle. "I don't think it could come to anyone as a surprise that if you miss your pre-season and then break your leg that minor injuries can occur if you then start into Premier League games in that intensity," Slot said. "Just a bit of bad luck for him that in a moment of time he comes back, then Hugo [Ekitiké] gets injured and we need him more."Guardiola's Warning Against ComplacencyAfter Saturday's FA Cup triumph over Chelsea, the 17th major trophy of Pep Guardiola's decade leading Manchester City, he reminded his players to never be complacent. "The most important thing is that [winning] trophies is good. Know what it takes to compete and win but don't take it for granted," the City manager said. "You start to believe that you are special, you will not win the FA Cup. Special we are not. The moment that we think [that], we will not be in these places. That is one of the things that through the years, we were OK with: knowing how difficult it is to win."Chelsea's Wembley Woes ContinueChelsea's dressing room and boardroom have been in a constant state of flux since Todd Boehly's BlueCo bought the club in 2022, but one thing has remained the same: they have a dire recent record in cup finals at Wembley. In the first decade after the stadium reopened in 2007, Chelsea won five of their six cup finals under the arch. Saturday's 1-0 defeat to Manchester City was their eighth loss in nine finals since 2017. Scoring goals at Wembley has also proven hard going, particularly since the departure of Didier Drogba (five goals in his five Wembley cup final starts). Christian Pulisic was the last Chelsea player to score in a domestic cup final, against Arsenal in front of empty stands in 2020. That's five finals in a row without a goal. It is a dry spell that can be tied to a young squad's relative lack of experience, but that argument does not stand up if you take into account the seven goals fired in against Paris Saint-Germain and Real Betis in the Club World Cup and Conference League finals just last year. Xabi Alonso is unlikely to have European football to play with next season, putting even more emphasis on Chelsea ending their Wembley drought and filling their silverware quota in domestic competitions.What's Next in the Premier League RaceWith the season drawing to a close, several key fixtures remain that could determine the final standings. Tottenham's survival hopes hinge on their match against Chelsea, while Liverpool will be hoping to end their injury-hit season on a positive note against Brentford. Manchester City, meanwhile, will be looking to build on their cup success as they continue their pursuit of more silverware in the final weeks of the season.