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Israel has confirmed that it has struck a uranium processing facility in the central Iranian city of Yazd, in an escalatory move that comes as regional diplomats have been attempting to broker an agreement to halt the joint US-Israeli war on Iran.The Israeli Air Force said it hit a plant used to extract raw materials essential to the uranium enrichment process, describing it as a 'unique facility' in Iran's nuclear infrastructure. Iran's Atomic Energy Organization confirmed the strike, but said there were no casualties or radiation leaks.A projectile also hit near the Bushehr Nuclear Power Plant, Iran's Atomic Energy Organisation said. The attack caused 'no casualties, financial, or technical damage,' the organisation said.Friday marked day 28 of the conflict, and the assault by the Israeli army was part of a broad wave of attacks on sites across the country. The Khondab Heavy Water Complex in central Iran was hit, as well as two major steel plants: the Khuzestan Steel facility and the Mobarakeh Steel complex in Isfahan.Foreign Minister Abbas Araghchi said Iran will 'exact heavy price' for Israeli attacks on several important infrastructure sites. 'Israel has hit 2 of Iran's largest steel factories, a power plant and civilian nuclear sites among other infrastructure,' said Araghchi in a post on X.Strikes also hit areas in and around Tehran, the city of Kashan and Ahwaz, while 18 people were killed in Qom. More than 1,900 people have been killed in US-Israeli attacks on Iran since the war began on February 28.Iranian officials said US-Israeli strikes have damaged at least 120 museums and historical sites across the country since hostilities began.Negar Mortazavi, a senior non-resident fellow at the Center for International Policy, told Al Jazeera that even Iranians who had been critical of their own government increasingly view the war as an assault on the Iranian people rather than its leadership, saying the targeting of water, electricity, gas, cultural heritage, schools and hospitals was 'unacceptable.'Israeli Defence Minister Israel Katz said Israel would 'intensify' its campaign and expand the range of sites it targets, accusing Tehran of deliberately directing missiles at Israeli civilians.

The UK is on the brink of a medicine shortage crisis, with experts warning that the country is just weeks away from feeling the effects of the ongoing conflict in Iran. The war has already disrupted the supply of essential raw materials, including oil, gas, crop fertiliser, and helium.The pharmaceutical industry, which relies heavily on imports, is particularly vulnerable to these disruptions. India, known as the 'pharmacy of the world', produces a significant proportion of generic drugs and active pharmaceutical ingredients (APIs) used globally. However, with the Strait of Hormuz largely closed due to the conflict, the transportation of these vital supplies is becoming increasingly difficult.Medicine prices are also expected to rise as a result of the conflict. The US-Israel war on Iran has doubled air freight costs, which could make some medicines loss-making to supply to the NHS. While suppliers have long-term pricing agreements with NHS hospitals, they have more flexibility to increase prices for drugs supplied to GP practices and pharmacies.The UK's reliance on imported medicines is significant, with about half of its medicines produced domestically, a third coming from India, and another chunk from the EU. During the Covid pandemic, paracetamol and other painkillers were in short supply in Britain and elsewhere, as drugmakers in India struggled to keep up with demand.Medical distributors typically stock six to eight weeks of supplies to avoid shortfalls, but if the conflict drags on, drug shortages could emerge in only a few weeks' time. Experts warn that the overall ripple effect on the industry is significant, with the patient ultimately picking up the tab, either directly or via public health systems like the NHS.

Mohaddeseh Fallahat recalled the ordinary morning of February 28 when she prepared her children for school, never imagining it would be the last time she would see them alive. That simple morning routine now haunts her as she struggles to cope with the devastating loss of her two children.Speaking through tears to the United Nations Human Rights Council in Geneva via videolink, Fallahat described the unbearable pain of sending her children off with a smile, only to be met with silence. "My heart burns with pain," she shared, as the memory of their final words—"Mum, come pick us up after school"—repeats endlessly in her mind.Her children were among more than 170 people killed when United States Tomahawk missiles struck the Shajareh Tayyebeh Girls' School in Minab, southern Iran, during the initial hours of the US-Israeli assault. The majority of victims were schoolgirls, marking one of the deadliest attacks on educational facilities in recent memory.Iran's Foreign Minister Abbas Araghchi addressed the council with strong condemnation, asserting that the attack was no mere miscalculation. "No one can believe that the attack on the school was anything other than deliberate and intentional," he stated, pointing to the advanced precision technologies claimed by American and Israeli forces.Araghchi accused the US and Israel of "slaughtering [victims] in cold blood" and committing "the worst humanitarian crimes with impunity." He called on UN member states to denounce what he described as a "blatantly unjustified" war on Iran, warning that indifference would bring no lasting security or peace.UN special rapporteur on the right to education, Farida Shaheed, presented evidence suggesting the school was "each struck individually by precision munition," indicating intentional targeting. However, ongoing investigations suggest the attack may have resulted from "outdated intelligence" used by the US military.Shaheed emphasized that "the killing of children can never, ever be justified" and highlighted the broader impact on education in Iran, where more than 600 schools and education facilities have been destroyed or severely damaged by US-Israeli attacks, with at least 230 children and teachers confirmed dead.UN Human Rights chief Volker Turk reinforced that targeting schools constitutes a grave violation of international law, stating: "Whatever differences countries have, we can all agree they will not be solved by killing schoolchildren."

Ella Baron, a renowned cartoonist, has created a thought-provoking cartoon titled 'Ella Baron on Donald Trump and the Iran war – cartoon' for The Guardian. The cartoon, which can be viewed on The Guardian's website, offers a visual commentary on Donald Trump's approach to the Iran war and its implications on global politics.The cartoon is part of The Guardian's series on US-Israel war on Iran, providing readers with a unique perspective on the complex relationships between the United States, Israel, and Iran. By using satire and humor, Ella Baron aims to stimulate discussion and raise awareness about the potential consequences of conflict in the Middle East.As a prominent cartoonist, Ella Baron's work often addresses pressing global issues, and this cartoon is no exception. Her depiction of Donald Trump's involvement in the Iran war is likely to spark conversation and debate among readers, encouraging them to think critically about the situation.

Iran's men's football team, Team Melli, has been training in southern Turkiye as they prepare for two upcoming friendly matches before the FIFA World Cup. The team's preparations come against the backdrop of the US-Israel war on Iran, which is likely to attract heightened attention during the World Cup.The team held a training session in Belek, Antalya, with tightly restricted media access. Officials stated that they wanted to avoid distractions before the matches, which are critical to their World Cup preparations.Iran's football federation is in discussions with FIFA about moving its World Cup matches to Mexico from the US due to concerns over player safety. The friendly matches were originally scheduled to take place in Jordan but were moved to Turkiye following the outbreak of the war on Iran.The team will play against Nigeria on Friday and Costa Rica on Tuesday. Striker Sardar Azmoun was omitted from the squad after posting a picture on his Instagram feed of a meeting with Dubai's ruler Mohammed bin Rashid Al Maktoum. Iranian media reported that Azmoun had been expelled from the national team for a perceived act of disloyalty to the government.

Israeli Defence Minister Israel Katz confirmed that an Israeli air strike killed Alireza Tangsiri, commander of Iran's Islamic Revolutionary Guard Corps (IRGC) navy, on Wednesday night. Katz stated that the assassination targeted other 'senior officers of the naval command'.Katz described Tangsiri as the man 'directly responsible for the terrorist operation of mining and blocking the Strait of Hormuz to shipping'. He added that Tangsiri was 'blown up and eliminated'. Tangsiri was a 'well-known commander' who shaped Iran's naval doctrine and developed drones for military maritime use. He was also involved in overseeing Iran's efforts to assert control over the Strait of Hormuz by blocking some vessels.Since the start of the US-Israel war on Iran on February 28, Israel has announced the assassination of several top Iranian officials. The civilian toll is significant, with at least 1,937 people killed, including 452 women and children, and 24,800 injured, according to Iran's Deputy Health Minister Ali Jafarian.Admiral Brad Cooper, commander of US Central Command, said the assassination of Tangsiri 'makes the region safer'. US forces have destroyed about 92 percent of Iran's large naval vessels in ongoing operations.

UK Chancellor Rachel Reeves is facing pressure to raise taxes on businesses generating 'windfall' profits linked to the US-Israel war on Iran to fund emergency cost of living support for UK households.A group of leading charities, campaigners, and trade unions, including Greenpeace UK, the National Education Union, and Tax Justice UK, have written an open letter to Keir Starmer and Reeves, urging the government to strengthen its existing North Sea energy windfall tax and introduce new levies for firms in other sectors that stand to financially benefit from the conflict.The letter highlights that energy companies, banks, agricultural commodities businesses, defence companies, and tech firms are likely to profit from the economic fallout of the war. The group argues that the extra revenue generated from taxing these 'excess profits' could be used to support households struggling with the cost of living and invest in the UK's future energy security.R Reeves has signalled that the government is ready to provide targeted help for households grappling with the economic fallout from the Middle East conflict, amid a surge in energy prices since the onset of the war. The chancellor has also warned companies that she will not tolerate corporates profiteering from the crisis, telling bosses that the Competition and Markets Authority has been put on notice to detect and crack down on price gouging.The UK already has a windfall tax on North Sea oil and gas firms, the energy profits levy, which is due to run until 2030. However, Reeves had been planning to ease the tax before the US and Israel attacked Iran on 28 February.

The US-Israel war on Iran has effectively closed the Strait of Hormuz, a critical shipping route for materials used in the production of various everyday products. As the conflict enters its fifth week, global oil shortages are forcing countries to take severe measures to conserve their reserves. While US gas prices have surged to their highest level in years, the impact of rising oil prices extends far beyond drivers. Oil is a crucial component in the supply chain, powering machines that manufacture goods and fueling trucks that transport them to stores. The price increases come at a time when many Americans are already strained by rising housing costs, grocery bills, and electricity statements. A recent Gallup poll found that a third of Americans have had to skip meals and forego other needs to afford their healthcare. Oil and Gas The average cost of gas in the US has jumped about 30% over the last month, with the national average hitting $3.97, the highest since 2023. Diesel, which fuels many trucks transporting goods, has increased by about 50%, or $1.69 more than it did a year ago. Higher diesel costs could soon affect transportation costs and grocery prices, as roughly 85% of agricultural goods are transported by trucks. The impact of oil and gas shortages on the supply chain can be categorized as first-order effects, such as higher prices at the gas pump, and second-order effects, including potential price increases for crops, semiconductor chips, and medical devices. Fertilizer Farmers are struggling as the spring growing season approaches, facing higher fertilizer costs and falling commodity prices. A third of global urea trade, a solid nitrogen fertilizer, passes through the Middle East region, with about 20% of imported fertilizer to the US coming from Qatar. Nitrogen fertilizer is critical to grow corn, which is cultivated by about 500,000 farmers in the US. The White House has promised to minimize disruptions to the US economy, with alternative sources of fertilizer being sought from around the world. Helium The conflict has disrupted the global helium supply after Iranian attacks in Qatar, the second-largest producer of helium after the United States. Helium is a key import used in aerospace, magnetic resonance imaging (MRI), and semiconductor chips that power AI. Jet Fuel Increases in oil prices could result in higher airfare and shipping costs. The price of jet fuel has doubled since the start of the war, according to the International Air Transport Association. United Airlines announced last Friday that it would have to cut flights due to the surging cost of fuel. < h2>Mortgage Rates Just as US mortgages were starting to fall in February, the average 30-year fixed mortgage rate ticked up to its highest level in months, reaching 6.22%. Mortgage rates are closely tied to the overall state of the economy, and the US Federal Reserve's decision to leave rates unchanged last week cited uncertainty in the economy, particularly with conflict in the Middle East.

US President Donald Trump has asserted that negotiations to end the war on Iran are ongoing, claiming Tehran is eager to make a deal. Speaking at the White House, Trump stated the US is talking to 'the right people' about a potential agreement, mentioning a 'very big present' related to 'oil and gas' allegedly gifted by Tehran. Trump's claims come as fighting continues, with Iran launching attacks on Israel and a strike near Iran's Bushehr nuclear plant. Iran's parliament speaker, Mohammad Baqer Ghalibaf, had previously dismissed Trump's claims as 'fake news.' Media reports suggest Washington has sent Iran a 15-point plan to end the war, which includes ending Iran's nuclear program and reopening the Strait of Hormuz. A Reuters/Ipsos poll found 61% of Americans disapprove of the attacks on Iran, while 35% approve. Iran's Ministry of Foreign Affairs acknowledged receiving messages from 'friendly countries' indicating a US request for negotiations. Negar Mortazavi, a senior non-resident fellow at the Center for International Policy, stated Iran would seek to end the war on its 'own terms,' including establishing deterrence and economic gains. Despite Trump's diplomatic efforts, Israeli military spokesman Effie Defrin said Israel's war plan remains 'unchanged,' aiming to 'deepen the damage and remove existential threats.' The US is reportedly preparing to send thousands of soldiers to the Middle East, fueling fears of a longer conflict.