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The Legacy of a Scientific Pioneer My husband Peer Bork, who has died unexpectedly aged 62, was a bioinformatician with a remarkable ability to identify new directions in science and carry out world-class research to push them forward. Revolutionizing Microbiome Research During his career, he progressed from the statistical analysis of the sequences of individual protein molecules, via the analysis of the human genome, to the bioinformatics analysis of whole microbial communities. Peer pioneered the computational analysis of the human microbiome, introducing the concept of gut enterotypes – in work that was highlighted in many newspaper articles as well as on the radio and TV. He went on to study microbial ecosystems worldwide and, at the time of his death, was involved in expanding a consortium that he had initiated to systematically document coastal ecosystems in Europe. All these studies required the creation of bioinformatics tools – software and curated datasets – which are now widely used by the scientific community in academia and industry. A Life in Science Peer was born in the former East Berlin, where his father, Joachim, worked in economic statistics, and his mother, Regina, had an administrative job in the construction industry. Owing to his mathematical abilities, he won a place at a high school specialising in mathematics and science, the Heinrich-Hertz-Oberschule. After military service on the border between East and West Germany, he studied biochemistry at the University of Leipzig. He followed this with a PhD in bioinformatics under the supervision of Jens Reich at the Central Institute for Molecular Biology of the Academy of Sciences of the GDR in Berlin. International Scientific Career After the fall of the Berlin Wall in 1989, Peer joined the European Molecular Biology Laboratory (EMBL) in Heidelberg in 1991 as a visiting scientist. He and I met there and married in Canterbury, Kent, in 1994. We had two sons, Udo and Robin, and family life involved many trips between Germany and Britain. EMBL became Peer's scientific home and he rose up the ranks to become interim director general in 2025. He was dedicated to furthering EMBL – an intergovernmental research organisation with six sites, including the European Bioinformatics Institute near Cambridge. He was an outstanding mentor. Awards and Recognition He made science both challenging and fun. Among his awards, which included honorary doctorates and the 2009 Royal Society and Académie des Sciences Microsoft award, he was particularly proud of the Nature award for mentoring in science he received in 2008. Final Scientific Journey He died in Taiwan, where he was due to speak at an international conference on the microbiome. He loved to travel and make friends all over the world. Peer is survived by me, his sons, by a granddaughter and his mother.

US captain Jim Furyk has warned that the United States must make the Ryder Cup a year‑round priority if it hopes to break a streak of losses, outlining both an immediate goal of winning at Adare Manor in 2027 and a longer‑term cultural blueprint.Furyk’s Call for a Cultural Overhaul Ahead of the 2027 Ryder CupFuryk, appointed captain for a second time, said his job is to “create a culture, a chemistry amongst them” and to set two sets of goals: a short‑term aim to win on foreign soil and a long‑term plan to build continuity for future players and captains.Recent Ryder Cup Record Highlights US StrugglesUS have won 2 of the last 8 Ryder Cups.Victory for Europe at Bethpage in 2025 left the US trailing.Furyk was captain when the US were “trounced” in Paris 2018.Short‑Term Blueprint: Targeting Victory at Adare ManorThe immediate objective is to “scratch and claw” for a win at the 2027 event in Ireland, a feat the US has not achieved on foreign soil for many years.Long‑Term Vision: Building Continuity and Year‑Round FocusFuryk wants to establish a “blueprint” that ensures consistent preparation, player continuity, and a permanent emphasis on the Ryder Cup each year.Potential Backroom Role for Tiger Woods and European CounterpartsFuryk indicated interest in involving Tiger Woods in the backroom team, despite Woods’ ongoing recovery from a March car crash. Across the Atlantic, European captain Luke Donald confirmed that the recent dispute involving Jon Rahm and the DP World Tour has been resolved, keeping Europe’s squad unified.Outlook: US as Underdogs with a Chance to UpsetWhile Europe enters the 2027 Ryder Cup as heavy favourites, Furyk believes the US can relish the underdog role and that his cultural shift could narrow the gap.

The Landmark Court Ruling A court in China has ruled in favour of a worker whose company replaced him with artificial intelligence (AI), awarding him more than £28,000 in compensation. The Case Details The worker, whose surname is Zhou, joined a tech company in the eastern city of Hangzhou in 2022 as a quality assurance supervisor overseeing large language models used in AI products. The company later said AI could do his job and offered him a demotion and a 40% pay cut. When he refused, the company fired him. The Compensation Awarded The Hangzhou intermediate people’s court ruled last month that the company had been wrong to fire him and ordered that he be paid 260,000 yuan in compensation. The Impact on Labor Rights The case has attracted widespread attention as an example of how China can balance the country’s enthusiastic adoption of AI with job security, especially at a time of high youth unemployment. 17% of people aged 16 to 24 are currently unable to find work in China. The Future Outlook Experts say there are signs of a shift in Beijing’s approach to job losses caused by AI, with a focus on addressing unemployment related to AI and ensuring employers assume corresponding social responsibilities.

Lead: Uline pauses Kenosha distribution center construction Uline, owned by billionaire Trump supporters Richard and Elizabeth Uihlein, has asked Kenosha’s city planning commission to extend its conditional‑use permit, effectively pausing the build‑out of a more than 1 million‑sq‑ft distribution facility until at least 2027. The company cites “current economic conditions and available space within Uline’s existing network” as the reason for the delay. Uline Requests Extension for 1‑Million‑Sq‑Ft Kenosha Facility Location: Kenosha, Wisconsin Facility size: > 1 million sq ft Permit extension granted for 12 months Construction pause expected to last until 2027 or later Financial Scale and Political Contributions Highlighted Richard Uihlein donated nearly $80 million to a pro‑Trump political action committee in 2024 The Uihleins surveyed their own employees in October 2024 about voting intentions In January 2026 a Uline employee resigned over the couple’s political support Implications for Wisconsin’s Battleground Economy The pause comes in a swing state where Donald Trump won in 2016 and 2024 but lost in 2020, raising questions about how donor‑driven development projects may be affected by broader economic uncertainty and political calculations. Potential Delays and Political Repercussions Through 2027 If economic conditions do not improve, the extended permit may be further delayed, potentially limiting job creation in Kenosha and influencing local perceptions of Trump‑aligned donors ahead of future elections.

The Sunderland Pivot: From Exclusive Production to Contract ManufacturingNissan is actively exploring a strategic shift at its UK flagship plant in Sunderland, moving away from a model of exclusive production toward contract manufacturing for external partners. CEO Ivan Espinosa confirmed that the company is "looking at options" to bring in additional volume, specifically mentioning talks with Chinese automaker Chery. This potential collaboration comes as Nissan struggles with faltering demand for its own vehicles, having announced the closure of one of its two production lines at the facility.Financial Strain and Volume ConstraintsThe decision to consider outsourcing production is driven by a critical volume crisis. Espinosa emphasized that the Sunderland plant is "viable" but faces challenges due to insufficient output. This financial pressure is reflected in Nissan's recent performance, which posted a net loss of ¥533bn (£2.5bn) for the year to March. Operating profits fell nearly 12% on the previous year, forcing the company to merge production lines and cut 900 jobs across Europe, including roles in the UK.The European Auto Industry's Strategic ShiftNissan's potential move mirrors a broader trend in the European automotive sector, where legacy manufacturers are monetizing underused capacity to survive. This trend is driven by Chinese competitors who can undercut European prices due to lower production costs. Notable examples include Stellantis building cars for Leapmotor in Spain and Ford reportedly discussing plant sales with Geely. Furthermore, BYD is actively negotiating with Stellantis and other European firms to take over idle factories, signaling a new era of cross-border collaboration.A New Era of Cross-Border CollaborationLooking ahead, the automotive landscape is shifting from pure competition to strategic partnerships. Espinosa, appointed a year ago with a mandate to restore profitability, views external collaboration as essential for survival. As Chinese brands like Chery and BYD aggressively expand into Europe, the traditional boundaries between domestic and foreign manufacturing are blurring, suggesting that contract manufacturing will become a standard survival strategy for struggling legacy automakers.

The LeadJennie Garth, known for her role as Kelly Taylor in 'Beverly Hills, 90210,' opens up about the psychological impact of early fame and how she found new purpose in her 50s. The 54-year-old actress, who felt 'stuck' and unfulfilled as her daughters grew up, has launched a podcast and book titled 'I Choose Me,' sharing her journey of self-discovery and the lessons learned from her decades in Hollywood.Finding Purpose at 50Approaching her 50s, Garth experienced a classic midlife crisis, questioning her path and purpose after noticing potential acting jobs becoming 'few and far between.' The deaths of her 90210 co-stars Luke Perry in 2019 and Shannen Doherty in 2024 intensified her sense of urgency, prompting her to share what she's learned with other women experiencing similar standstills. Her new venture, 'I Choose Me,' named after an iconic line from her character on the show, combines memoir and self-help as Garth reflects on her journey from teenage star to mature woman finding her voice.The Price of Early FameGarth candidly admits that her early fame 'screwed with her mind,' describing how she spent 20 years 'trying to keep her head above water.' Starting on the hit show at just 18, she felt developmentally 'held back from the realities of the world,' watching peers experience normal milestones while she was 'slammed into' fame. The experience left her questioning how her unusual path affected her relationships and personal growth, as she struggled to form normal connections while constantly being judged and typecast in the industry.Hollywood's Changing LandscapeThe actress reflects on the sexism she faced in the 90s, noting how young female actors were 'exposed to far more than they should' in terms of sexualization and discrimination. She recalls unspoken expectations about appearance and the pressure to conform to certain standards, including her own decision to get breast enhancement at 24. Garth also discusses how the industry typecast her and her co-stars, keeping them in a 'sort of Aaron Spelling-nighttime-soapy category' that limited their growth opportunities, despite the quality of their work.A New ChapterNow in her 50s, Garth feels she's finally 'caught up' developmentally and is embracing her age with greater wisdom and resilience. Through therapy and self-help, she's found a new voice and purpose, sharing her experiences to help other women navigate similar challenges. Her journey from teenage star to empowered woman reflects both the lasting impact of early fame and the potential for reinvention later in life, as she continues to work while also focusing on personal growth and helping others find their own path to self-acceptance.

The Unlikely Hero of Normal Bob Odenkirk continues his new career as the everyguy action hero in this cynically bleak gonzo actionfest, co-written by Odenkirk himself with John Wick creator Derek Kolstad. The director is Ben Wheatley, who shows the same kind of gunplay that was exhibited in his single-location mayhem spectacular Free Fire from 2017. A Town of Deception The setting is a place of Fargo-esque wholesomeness: a little town in Minnesota called Normal where Ulysses, played by Odenkirk, shows up as the interim sheriff, a decent guy just filling in after the previous sheriff was found dead in the snow in strange circumstances. Ulysses is depressed and battling a drinking problem after an unexplained violent end to his last job, which caused him to separate from his wife. The Dark Secret Unfolds Yet something is very wrong: when a bank robbery happens in this one-horse town, events are set in train which reveal to Ulysses that everything about Normal, like the blandly prosperous law practice in Sydney Pollack’s film The Firm, rests on a single, awful secret that he is about to uncover. It’s entertaining and bizarre chaos, anchored by Odenkirk’s hangdog air of gloomy resignation to the violent mess which he has to clean up. The Film's Release Normal is in UK and Irish cinemas from 15 May.

The Cultural Phenomenon of Northern SoulAlan Byron's film is an absorbing docu-celebration of the northern soul scene that flourished from the late 1960s to the end of the 1970s. It was a fascinating, vernacular youth movement and a kind of regional open secret: a club culture, a zine culture, a music-and-fashion culture which uncynically invented and sustained itself without the need for any svengali figure from London to keep the show on the road. Northern soul fans were passionate about thumpingly sensual mid-60s American soul, a musical style which they kept alive on the all-night dancefloor by doing spectacular spins and drops, while the official voice of the music business decreed that disco or MOR rock or glam or heavy metal was where it was at.The Wigan Casino LegacyDJs would travel to the US to sort through the boxes and mounds of 7-inch vinyl which had been discarded by Motown and the radio stations – basically prospecting for gold – and bring it back to northern English clubs. The principal clearing house was the mighty Wigan Casino which mounted legendary all-nighters from 2am to 8am, attracting soul fans from miles around who knew that this was the only place where certain tracks could be heard. (No Spotify or Apple Music in those days.)Cultural Resistance and RecognitionLicensing laws meant that only Coca-Cola could be served, but dancers took amphetamine, a part of the northern soul scene that has perhaps only recently been acknowledged fully, and is in fact not looked into all that closely here. It carried on through the 1970s, all but ignored by the cultural gatekeepers of the south; that is, until documentarist Tony Palmer brought his cameras and lights into the club to make The Wigan Casino as part of Granada TV's This England strand, an outsider incursion grumblingly resented at the time but now treasured as a unique archive record.Understanding the Movement's IdentityWhat is fascinating about northern soul is the way it survived under the media-cultural radar and appears to resist larger interpretive analysis. It was not overtly political, unlike punk or reggae, and there is no consensus here about the status of the northern soul consumers. Were they unemployed, poor, alienated and angry? Not necessarily. Many here recall having good jobs and apprenticeships of the sort they wouldn't have now.Enduring Influence and MysteriesAs for whether it was revolutionary in any sexual sense, commentator Paul Mason suggests that there was something homoerotic in the male atmosphere. Maybe, yes: but no one here has any first-hand experience to share about that. As for the Wigan Casino itself, the building's lease was terminated by the council at the end of the 70s prior to planned demolition; just when the tenants might have disputed this, the building mysteriously burned to the ground. (Maybe we need David Peace to write a novel about that.) Northern soul was clearly the godfather of the club and rave scenes of the 90s and beyond, but for me, a question remains: what did the American acts themselves think of it? Were they ever tempted (or invited) to play live at the Wigan Casino?

What the 2026 Federal Budget Aims to FundInfrastructure upgrades, including roads, bridges, and broadband expansion.Defense spending adjustments reflecting strategic priorities.Social programs such as Medicare, Medicaid, and education grants.Climate‑related investments and clean‑energy incentives.Key Fiscal Figures Highlighted in the VideoProjected overall federal outlays: roughly $5.2 trillion.Estimated deficit for fiscal year 2026: in the range of $1.4–$1.6 trillion.Revenue outlook: anticipated $3.6 trillion from taxes and other sources.Debt‑to‑GDP ratio expected to hover around 115 % by year‑end.Implications for Taxpayers and the EconomyPotential modest adjustments to income‑tax brackets to offset revenue shortfalls.Increased funding for low‑income housing and child‑care assistance.Long‑term debt trajectory could influence borrowing costs and inflation expectations.Infrastructure spending is projected to generate $200 billion in short‑term job growth.Looking Ahead: Potential Policy ShiftsCongress may debate additional revenue measures, including capital‑gains tax tweaks.Future budgets could prioritize climate resilience, reshaping energy subsidies.Monitoring the deficit trajectory will be crucial for Federal Reserve policy decisions.