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The Personal Mission Behind the InvestmentReed Jobs, son of Apple co-founder Steve Jobs, is bringing his oncology-focused venture capital fund Yosemite to the UK, seeking investment opportunities in cancer care. The 34-year-old's mission is deeply personal, stemming from witnessing his father's death from a rare form of pancreatic cancer in 2011 at age 56. "I saw my dad have cancer when I was a kid, and unfortunately that happens far too often. And that really motivated me to try to transform outcomes for other people out there," Jobs explains.Yosemite's Healthcare Investment StrategyThe San Francisco-based venture fund, named after the California national park where his parents married, manages over $1 billion in assets and has already invested in approximately 20 healthcare startups. Yosemite focuses on innovative approaches to cancer treatment, including gene therapy, cancer vaccines, radiopharmaceuticals, and artificial intelligence. Notable investments include Tune Therapeutics, Azalea Therapeutics, Chai Discovery, and Sage Care in the US, with several UK companies in their portfolio that haven't been publicly announced.Financial Backing and International PartnershipsYosemite receives investment from LifeArc, a UK not-for-profit group focused on rare diseases that was established in 2000 as part of the UK's Medical Research Council. The fund also has partnerships with Oxford and Cambridge universities, where it has provided philanthropic grants. Additional backing comes from US biotech company Amgen, Massachusetts Institute of Technology, Memorial Sloan Kettering Cancer Center in New York, and billionaire investor John Doerr, following a fundraiser earlier this year.UK's Position in Global Cancer Research"Research here is world class," Jobs states during his visit to London for a life sciences conference hosted by LifeArc. The UK's strong academic institutions and research environment make it an attractive location for healthcare investment. Yosemite's international investment strategy includes the UK, where the fund aims to connect with pharmaceutical partners and academics to advance cancer treatment possibilities.Future Vision for Cancer TreatmentJobs envisions a future where cancer shifts from being an "end-stage disease" to an illness that is diagnosed early, monitored, and treated—similar to advances made with HIV and cardiovascular disease. "Today far too many cancers are either diagnosed incidentally, because there's no good early biomarker, or only diagnosed once they are metastatic and extremely advanced," he notes. The fund is particularly focused on immunotherapy, which Jobs identifies as "one of the areas I think is going to have the most promise for patients in the next couple of decades."

The Art of the Midfield SpellEnzo Le Fée is not just a footballer; he is a magician on the pitch, capable of turning defensive chaos into attacking opportunities with a single glance. Describing himself as a "magician" off the field, Le Fée brings that same sense of wonder to his game, utilizing an unerring ability to spot attacking possibilities that others miss.Technical Versatility: Le Fée can operate as a deep-lying No 10, a No 6, or an No 8, adapting to Régis Le Bris’s tactical needs seamlessly.Defensive Discipline: Despite standing at 173cm, he is a surprisingly effective tackler and presser, proving that creativity requires a strong work ethic.Intelligent Play: He understands the rhythm of the game, knowing exactly when to slow down to draw defenders out or speed up to exploit space.A Breton Bond: The Le Bris-Le Fée DynamicThe success of Sunderland’s season is deeply rooted in the special relationship between Le Fée and his manager, Régis Le Bris. Their connection dates back to Le Bris’s time at Lorient, where he nurtured Le Fée’s precocious talent.Le Fée credits Le Bris with providing the confidence he needed to leave Roma and join Sunderland permanently. This mentorship has been crucial for Le Fée, who has overcome personal tragedy—losing his father to suicide at a young age—to become a leader in the dressing room.The Antidote to Robotic FootballIn an era dominated by aggressive grappling and set-piece strategies, Le Fée represents a refreshing return to instinctive football. His refusal to play a "painting-by-numbers" game has endeared him to Sunderland fans who crave joy and unpredictability.Le Fée’s philosophy aligns with his idol Pedri, emphasizing that football is about "what’s inside your head" rather than physical stature. This approach has made him a target for Premier League rivals, including Liverpool, who are reportedly keen on his services.The Magic Man's Next ActWith two games remaining in the season, Le Fée is focused on securing Conference League qualification for Sunderland. While he has ambitions to break into the France national team and play in the Champions League, he remains grounded, stating, "My head is here, my heart is here."Le Fée’s journey suggests a bright future, not just for Sunderland, but for elite European football, provided he continues to balance his creative flair with the defensive rigour required at the highest level.

The LeadFalling seriously ill, like falling in love, can happen all of a sudden – although this film is not exactly about either. Ryusuke Hamaguchi's new movie, co-scripted with the Franco-Japanese screenwriter Léa Le Dimna and his first not set entirely in Japan, is a bold and high-minded if rather pedagogic work that spreads itself over three hours. It's tender and sometimes beautifully made, but also contrived and occasionally features some too-good-to-be-true caring characters. Frankly, it's rather precious.The Film's International VisionHamaguchi and Le Dimna have taken as their starting point the nonfiction book "You and I: The Illness Suddenly Get Worse" by Makiko Miyano and Maho Isono, a meditative correspondence between a philosopher and medical professional on the subjects of love and mortality. Hamaguchi has opened this out to create a drama set in Paris and Kyoto, and it's incidentally hard not to suspect that Hamaguchi, like many a celebrated movie director spending so much time on the international festival circuit, has been led to create an uneasy international mixture.Care Home Dynamics and CharactersMarie-Lou (Virginie Efira) is the director of a private care home in Paris called the Garden of Freedom, where they practise a care technique called "humanitude," a time-consuming patient-centred approach that exasperates old-fashioned nurse Sophie (Marie Bunel). It needs more staffing facilities than the home is prepared to provide and, in any case, Marie-Lou has a bad habit of being patronising to those who question her. For all that, there are some lovely scenes with caregivers and patients, and these observant, unfussily compassionate moments are where the film works best.Cross-Cultural ConnectionsMarie-Lou is stressed and overworked, and her life is upended when she encounters an autistic Japanese teen called Tomoki (Kodai Kurosaki) in the street, apparently lost; he is being looked after by his grandfather, Gorô (Kyōzō Nagatsuka), an actor in town performing in an experimental piece about psychiatric care in which Tomoki is encouraged to take part if he feels like it. The show is directed by Mari (Tao Okamoto), and her stylish calm and intelligence entrances Marie-Lou; they are clearly on the verge of an intense friendship and perhaps more, although the film is reticent on this last point.Philosophical Exchanges and Narrative ConcernsMarie-Lou comes to a performance, stays for the Q&A; afterwards and reveals herself to be fluent in Japanese, asking questions of Mari in that language which touch on Mari's very serious illness. Some in the audience rather plaintively – and understandably – call for the conversation to be in French, though this film comes close to being insufferable when Gorô solemnly tells everyone that their exchange was so intimate and meaningful that the audience should be content with simply sensing that.The Film's Strengths and WeaknessesAll of a Sudden works best entirely outside the exotically overwritten, overthought bond between Mari and Marie-Lou. The realist set pieces are very moving, showing us patients with dementia surrounded by their families, and also showing us, often with photos of their younger selves in demanding jobs, how these patients have changed. The film's high concept is a little self conscious.All of a Sudden screened at the Cannes film festival.

Gunmen Storm Mussa School, Seizing Dozens of PupilsAt about 9 am (08:00 GMT) on Friday, suspected insurgents on motorcycles entered Mussa Primary and Junior Secondary School in the Askira-Uba Local Government Area of Borno State. Ubaidallah Hasaan, a nearby resident, reported that the attackers moved swiftly while classes were in session and carried away a large number of students.Scale of Recent Kidnappings Across NigeriaCurrent incident: "dozens" of students taken (exact number not disclosed).Earlier this month: 23 children abducted from an orphanage in Lokoja, Kogi State.Recent parallel raid: students seized from Baptist Nursery and Primary School in Oyo State.These events follow a pattern of mass abductions that have become a revenue stream for armed groups, echoing the infamous 2014 Chibok schoolgirl kidnapping.Why the Northeast Is Becoming a Security Black HoleThe community of Mussa lies adjacent to the Sambisa Forest, a long‑standing insurgent stronghold. Despite ongoing military operations, repeated attacks on schools highlight persistent gaps in state presence, especially in rural zones where government services are minimal.Analysts, including writer Gimba Kakanda, note that insurgencies thrive not only on ideology but also on terrain, supply routes, and local economies that operate beyond state control.Future Outlook: Anticipated Rise in Rural AttacksSecurity experts warn that attacks could increase throughout 2026, driven by weakened government reach and the profitability of kidnappings. Policymakers face pressure to bolster protection for schools, improve intelligence sharing, and address underlying socioeconomic drivers such as chronic poverty and educational exclusion.

The Target: A Senior Architect of Iran’s Proxy NetworkThe United States Department of Justice has taken a decisive step in dismantling Iran’s global terror infrastructure by arresting and charging Mohammad Baqer Saad Dawood al-Saadi, a 32-year-old Iraqi national identified as a senior commander of the Iran-backed group Kataib Hezbollah. The operation, executed with precision by the FBI and international partners, marks a significant blow to the group's operational capabilities.Federal prosecutors allege that al-Saadi has been an active member of the group since at least 2017, working closely with Iran’s Islamic Revolutionary Guard Corps (IRGC) to advance its regional operations. Investigators revealed that al-Saadi maintained personal relationships with top-tier military leaders, including the late IRGC-Quds Force commander Qassem Soleimani. The suspect reportedly used social media platforms like Snapchat and Telegram to promote agendas and celebrate bombings, effectively serving as a digital recruiter and strategist.Global Footprint: 18+ Attacks Across Three ContinentsThe scope of al-Saadi’s alleged activities reveals a sophisticated network designed to pressure the US and Israel. According to the criminal complaint unsealed in Manhattan federal court, the suspect is accused of involvement in at least 18 attacks and attempted attacks spanning the US, Canada, and Europe.European Targets: The complaint details a firebombing of a Bank of New York Mellon building in Amsterdam and a thwarted attack on a Bank of America office in Paris, where French police discovered a homemade petrol and firework bomb containing 0.65kg of explosives.North American Targets: Al-Saadi allegedly coordinated a shooting at the US consulate in Toronto and a stabbing in London that wounded an American citizen.Domestic Threats: The plot extended to US soil, where al-Saadi allegedly offered $10,000 in cryptocurrency to launch simultaneous attacks on a New York City synagogue and Jewish centers in California and Arizona.FBI Director Kash Patel confirmed that al-Saadi was arrested overseas and brought to the US, describing him as “another high-value target responsible for mass global terrorism.” Patel praised the operation as a “righteous mission executed brilliantly,” crediting US Ambassador Tom Barrack in Turkiye for leading the joint operation.Strategic Implications for US-Iran RelationsThe arrest underscores the persistent and evolving threat posed by the Iranian regime and its proxies. New York City Police Commissioner Jessica Tisch noted that the case “puts into stark relief the global threats posed by the Iranian regime and its proxies.”The timing of the arrest is particularly sensitive, occurring amidst heightened military conflict between the US, Israel, and Iran. Prosecutors allege that al-Saadi became a central figure in coordinating international retaliation through a front group, frequently utilizing teenage suspects to execute attacks, thereby complicating intelligence and law enforcement efforts.Legal Battle and Future EscalationAl-Saadi appeared in court on Friday, facing a six-count criminal complaint that includes conspiracy to provide material support to foreign terrorist organisations and conspiracy to bomb a place of public use. If convicted on the terrorism and explosives counts, he faces a maximum penalty of life in federal prison.Despite the serious charges, al-Saadi’s defense team has argued that he is a “political prisoner” and a “prisoner of war,” claiming persecution solely due to his ties to Soleimani. His lawyer also highlighted that al-Saadi has been kept in solitary confinement since arriving at a federal jail in Brooklyn, a condition the defense describes as “unusual.” As the legal proceedings unfold, this case is likely to serve as a precedent for future prosecutions of Iranian-backed operatives.

The Announcement and Its Immediate ContextPresident Donald Trump posted on Truth Social that a joint U.S. and Nigerian operation had killed Abu‑Bilal al‑Minuki, described as ISIL’s global second‑in‑command. The statement, released on May 16, 2026, frames the strike as a decisive blow against the “most active terrorist in the world.”Joint US‑Nigeria Operation Targets ISIL’s Global DeputyThe mission, described as “meticulously planned and very complex,” combined American special‑operations assets with Nigerian armed forces. While operational details remain classified, the collaboration follows months of heightened U.S. engagement in the Sahel, including troop deployments and intelligence sharing.Sanctions, Funding, and the Financial Footprint of al‑MinukiAl‑Minuki has been on the U.S. sanctions list since 2023, restricting his ability to move money internationally. The State Department previously identified him as a senior leader in ISIL’s General Directorate of Provinces, a unit that channels “operational guidance and funding around the world.” Removing him may disrupt cash flows that sustain affiliate networks in Africa.Strategic Ripple Effects for ISIL’s Sahel NetworkAnalysts note that the Sahel remains ISIL’s most fertile recruiting ground. The loss of a high‑level coordinator could hamper command‑and‑control links between the core organization and regional cells, potentially reducing the frequency of cross‑border attacks. However, the group’s decentralized structure may allow other lieutenants to fill the gap.What the Killing Means for Future US‑Africa Counter‑TerrorismThe strike underscores a deepening U.S. security partnership with Nigeria, which has hosted hundreds of American advisors since early 2026. Expect continued joint training, intelligence exchanges, and targeted operations aimed at dismantling remaining ISIL leadership in the region.

Ukrainian President Volodymyr Zelenskyy vowed a response on May 15, 2026 after a Russian missile flattened a nine‑storey apartment block in Kyiv’s Darnytskyi district, killing at least 24 people, including three children. He said the attacks on Russia’s oil and military facilities were “entirely justified” and warned that Moscow’s strikes would not go unpunished. The Deadly Strike on Kyiv’s Darnytskyi District The strike, described by Ukraine’s air force as the largest aerial assault since the war began, hit a residential building in the capital, prompting a day of mourning and a solemn ceremony in Kyiv. Casualties and Immediate Military Response 24 civilians killed in Kyiv, including 3 children. Ukrainian forces reported a retaliatory long‑range drone attack on Russian energy and military sites on the same day. In Russia’s Ryazan region, a drone strike killed 4 people, including a child, and damaged one of the country’s largest oil refineries. Escalation of Ukraine’s Long‑Range Counter‑Strikes Zelenskyy said he had discussed “long‑range strikes” with senior military, security and intelligence officials, targeting more than 20 decision‑making centres across Ukraine, as well as his own office and state residence. Implications for Peace Talks and Regional Stability The attack comes after a recent three‑day ceasefire brokered by U.S. President Donald Trump, during which 205 prisoners of war were exchanged. Both sides had pledged to release up to 1,000 prisoners each, but the new violence threatens to stall further negotiations. Outlook: Continued Conflict Amid Diplomatic Efforts While Russian President Vladimir Putin suggested the war was nearing its end, Zelenskyy dismissed the claim, indicating that Ukraine will continue to target Russian infrastructure. The cycle of retaliation suggests that any near‑term peace settlement remains uncertain.

The Lead: Trump's China Boeing Deal AnnouncementPresident Donald Trump announced that China has agreed to purchase 200 Boeing jets, with a potential for the order to rise to as many as 750 planes, marking a significant but smaller-than-expected breakthrough in the aerospace market between the two economic powers. The deal, which reportedly includes GE Aerospace engines, was disclosed by Trump to reporters on Air Force One on Friday, though neither the Chinese government nor Boeing has officially confirmed the purchase agreement.The Event Details: Diplomatic Aviation DealThe announcement came during Trump's trip to Beijing, where Boeing CEO Kelly Ortberg was part of a large group of US executives seeking to sell products and services to China. The deal "includes approximately 200 planes and a promise of up to 750 if they do a good job," according to Trump, though specific details about which types of jets and delivery timelines were not immediately available.Industry sources indicate that Boeing was originally in negotiations for at least 500 narrowbody jets tied to the Beijing summit, with dozens of widebody jets potentially following. Trump also mentioned that Chinese President Xi would pay a return visit to Washington in September, suggesting it may become the focal point for the next tranche of potential plane orders.China has a history of bundling new orders with repeat announcements when unveiling trade packages tied to diplomatic visits by US and European leaders, leaving uncertainty about how many of the 200 planes announced represent new business versus aircraft already in Boeing's order backlog.The Data Analysis: Market Value and Financial ImpactThe market reacted negatively to Trump's announcement, with Boeing shares dropping nearly 4% on Thursday after the initial news and falling an additional 2.6% on Friday. GE Aerospace shares also declined by 2%, reflecting investor concerns about the deal's size and terms.Aviation intelligence firm IBA estimates the value of the 200-aircraft order at roughly $17 billion to $19 billion, assuming 80% of the mix consists of MAX jets. "This number, however, could increase to $25 billion if a larger proportion [about 40 percent] of the total order is announced for the widebody aircraft," according to IBA's Samuel Kenekueyero.An order for more than 500 jets would represent the largest in aviation history, surpassing IndiGo's 500-aircraft deal for Airbus narrowbodies, though China's purchase would likely be split among its three major state-run carriers.The Impact Analysis: Shifting Aviation DynamicsThe deal, if confirmed, would help Boeing narrow the gap with rival Airbus, which has pulled far ahead in China in recent years. For China, such a substantial order would secure capacity to continue growing its aviation market, even as production of its home-grown COMAC C919 narrow-body aircraft falls short of ambitious targets.However, concerns about after-sales support continue to weigh on purchasing decisions. "The reason China isn't buying is very simple: no one wants to buy something without guaranteed after-sales maintenance and support," noted Li Hanming, an independent expert on China's aviation industry. "Last May, the US was still threatening export restrictions on parts. If they impose parts embargoes like that, who would still dare to buy Boeing?"Wendy Cutler, senior vice president at the Asia Society Policy Institute and former acting deputy US trade representative, pointed out that both sides did not agree to extend the trade truce, which expires in five months. "What we expected and haven't seen thus far is not only Chinese confirmation of the jet purchases, but other Chinese mega-purchases as well, particularly in the agricultural and energy sectors," she stated.The Prediction: Future Trade Relations and Aviation MarketWhile the current Boeing deal represents a step forward in US-China trade relations, it appears to be "heavy on atmospherics, but light on substance" according to Cutler. The smaller-than-expected order suggests that China is proceeding cautiously with major purchases amid ongoing trade tensions and concerns about potential future restrictions.The September visit by Xi to Washington could potentially unveil additional aircraft orders, particularly for widebody jets, which would significantly increase the deal's value. However, without concrete assurances on after-sales support and a more stable trade environment, China may continue to diversify its aircraft suppliers and accelerate development of its domestic COMAC program.For Boeing, this deal represents a necessary but insufficient victory in reclaiming market share in China, the world's fastest-growing aviation market. The company will need to address fundamental concerns about reliability and supply chain stability to secure its long-term position in this critical market.

Lead: The London cinema in Soho became a focal point for a new wave of Jewish dissent as the documentary Planet Israel: A Cautionary Tale screened on the eve of Nakba Day, exposing fractures in British Jewish opinion about Israel’s actions in Gaza and the broader national narrative. The London Screening that Amplifies Dissenting Jewish Voices The film, directed by Gillian Mosely, blends interviews with historians, rabbis and everyday Israelis to examine how trauma, nationalism and militarisation shape Israeli society after the October 7 attacks. Audience members, including Holocaust survivor Stephen Kapos, reacted viscerally to the film’s sound design and AI‑assisted animation, underscoring the urgency of the conversation. Polling Reveals Deepening Rift Within Britain’s Jewish Community 40% of British Jews say Israel’s conduct in Gaza has weakened their attachment to the country. More than 33% no longer identify as Zionists. Only 12% express approval of Prime Minister Benjamin Netanyahu. These figures come from the Institute for Jewish Policy Research, indicating a measurable shift in sentiment that aligns with the documentary’s themes. Shifting Discourse: From Zionist Consensus to Critical Debate New publications such as Israel: What Went Wrong? by Omer Bartov and Here Where We Live Is Our Country by Molly Crabapple echo the film’s questioning tone. The Movement for Progressive Judaism, representing roughly a third of UK synagogues, has framed criticism of Israeli policy as a “Jewish obligation,” warning that current political directions may clash with core Jewish values. Future Trajectories: How Jewish Critique May Reshape Israeli and Global Politics Historians like Avi Shlaim argue that the growing “crisis between Israel and world Jewry” could pressure Israeli leadership to reconsider its narrative and policies. If the trend continues, political parties in the UK and the United States may feel compelled to adjust their stances on Israel, while Israeli civil society could see increased internal debate and potential policy reforms. Mosely concludes that while politicians are slow to respond, the cultural shift sparked by documentaries, books and grassroots activism may eventually force a realignment of public consensus on Israel’s role in the region.