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The conflict in the Middle East has taken a dramatic turn as Yemen's Iran-backed Houthis launched a second wave of attacks on Israel since joining the conflict on Saturday. The Houthis have vowed to continue their military operations in the coming days until Israel "ceases its attacks and aggression".In a significant escalation, two powerful explosions shook northern Tehran early on Sunday, with air defenses operating in the Iranian capital. The blasts occurred around 7:20 am, but it was not immediately clear what was targeted.Meanwhile, the US is reportedly preparing plans for ground operations in Iran, with the Trump administration having already deployed US Marines to the Middle East. The Pentagon is considering weeks of ground operations in Iran, potentially including raids on Kharg Island and coastal sites near the Strait of Hormuz.The entry of the Houthis into the conflict poses a direct threat to the Bab al-Mandab strait at the southern end of the Red Sea, a critical choke point in the supply chain of energy supplies and other trade in and out of the Middle East. A shutdown of the Bab al-Mandab, located between Yemen and the Horn of Africa, would amplify the already grave impact of the war on the global economy and could also reignite a Saudi-Yemen conflict.Exiled Iranian Crown Prince Reza Pahlavi has told one of the US's biggest annual gatherings of conservatives that he is ready to lead a new Iranian government and would call on the country's citizens to rise up when the "right moment arrives".Iran's Revolutionary Guard has threatened to target US universities in the Middle East after saying US-Israeli strikes had deliberately targeted two Iranian universities.

The US and Israel are intensifying their military campaign against Iran, with Senator Marco Rubio stating that the operation is expected to conclude in 'weeks, not months'. The conflict escalated with a surprise strike on 28 February that killed Iran's supreme leader, Ali Khamenei.Despite Iran's defiance and denial of negotiations, the US and Israel continue to target Iran's nuclear facilities and military sites. Israel's defence minister, Israel Katz, warned that attacks against Iran will 'escalate and expand' to additional targets and areas that assist the regime in building and operating weapons against Israeli citizens.The conflict has significant economic implications, with the Strait of Hormuz, a strategic waterway through which a fifth of the world's oil is usually shipped, being a key point of contention. The US has ordered thousands of marines and elite airborne troops to the region, possibly in preparation for a military effort to forcibly reopen the waterway.Iran has threatened to attack Saudi Arabia's Red Sea port of Yanbu and the Fujairah oil complex in the United Arab Emirates if a ground invasion takes place. The US president, Donald Trump, has issued an ultimatum to Iran, demanding that it allow free passage of shipping through the strait by 6 April or face the destruction of its energy plants.The conflict has resulted in significant casualties, with over 1,900 people killed and 20,000 injured in Iran, and 19 people killed in Israel. The humanitarian crisis in Lebanon has worsened, with a fifth of the population displaced and nearly 1,100 people killed.The G7 foreign ministers have reiterated the need for safe and toll-free freedom of navigation in the Strait of Hormuz and called for an immediate cessation of attacks against civilians and civilian infrastructure.