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Metabolic liver disease, or MASLD, is projected to affect 1.8 billion people worldwide by 2050, according to a recent study. This significant increase is primarily driven by rising obesity and blood sugar levels globally.MASLD, previously known as non-alcoholic fatty liver disease (NAFLD), is one of the most prevalent and rapidly growing liver conditions worldwide. The condition's prevalence has already seen a 143% increase in just three decades, from 500 million people in 1990 to 1.3 billion people in 2023.The study, published in the Lancet Gastroenterology & Hepatology journal, highlights that high blood sugar is the leading driver of MASLD-related health problems globally, followed by high BMI and smoking. These factors are strongly linked to type 2 diabetes and obesity.Regional disparities exist, with north Africa and the Middle East having disproportionately higher rates of MASLD. However, there have been sharp increases in the number of people affected in countries across the world, including the UK, Australia, and the United States.Despite the growing number of cases, the overall impact on health has remained stable, suggesting that advances in treatment and care are helping people live longer and healthier lives. However, the increasing number of cases still poses a risk of serious complications such as liver cirrhosis or cancer in the future.

On the closing night of Coachella’s opening weekend, Karol G broke new ground as the festival’s first Latina headliner. Introducing herself in English, the Colombian artist announced, “I am Carolina Giraldo from Medellín, Colombia, and today I am the first Latina woman to headline Coachella,” to a roar of cheers from a crowd waving flags from Mexico, Puerto Rico, Venezuela, Colombia and beyond.The moment echoed Beyoncé’s 2018 ‘Beychella’ debut, reminding fans that representation on this stage can reshape cultural narratives. Karol G’s 90‑minute performance combined dazzling costume changes, high‑energy choreography and a stage that seemed to rise two stories above the desert floor, creating a spectacle that felt both meticulously crafted and effortlessly vibrant.From the opening number “Latina Foreva,” where she strutted in a glittering gold bikini, to the cave‑like rave set that highlighted the “primordial wildness of women,” the show never lost its momentum. Even a half‑hour delay for lighting adjustments was quickly forgiven as the music surged forward, blending hard‑hitting tracks from her 2025 album Tropicoqueta with hits from 2023’s Mañana Será Bonito.Musically, the set was a tour of Latin genres. After a brief interlude, Karol G returned wearing a Carnival‑style feathered headdress for the mambo‑infused “Tropicoqueta.” She then invited an all‑female Mexican mariachi band for “Ese Hombre Es Malo,” followed by a duet with Becky G that mixed Spanish‑language celebration of Mexico and Colombia with a pointed nod to the United States’ immigration debate.Speaking amid the roar of the crowd, the 35‑year‑old artist said, “This is not just about me, this is about the Latina community, the love of my people,” acknowledging the delicate balance of celebrating Latin pride while the U.S. government tightens immigration policies. Her remarks highlighted the symbolic weight of performing such a vibrant, unapologetic Latin set on a stage that reaches millions worldwide.The finale reinforced the message of unity. After a soulful cover of Gloria Estefan’s “Mi Tierra,” Karol G launched into an EDM‑styled version of “Provenza,” complete with rainbow lasers, strobe lights, fireworks and a cascade of confetti. Three false‑ending beat drops and a megawatt smile underscored her point: the victory belongs to the entire Latin community, not just the performer.

Only one team has ever overcome a 2-0 defeat at home to go through in the history of the Champions League, but a Barcelona player was involved in a notable exception: Marcus Rashford scored the winner as Manchester United knocked out PSG in the round of 16 in March 2019. However, Atlético Madrid have never lost in 20 knockout stage games at the Metropolitano and their former home at the Vicente Calderón.

According to the latest Tottenham Hotspur financial statements, former executive chair Daniel Levy received £5.76 million in remuneration for the year ending 30 June 2025. That figure represents a 54% increase on his 2024 earnings and, as noted by football‑finance analyst Kieran Maguire, made him the highest‑paid director in the Premier League for the season. In stark contrast, the club’s women’s team—comprising 64 players and staff—had a combined salary and bonus total of £3.73 million, a 23% rise from the previous year. After accounting for social security and pension contributions, the overall wage bill reached £4.3 million, with an average annual earnings of roughly £58,000 per employee. This places Tottenham Women below several WSL rivals that have disclosed their 2024‑25 accounts, such as Brighton (£5 million), Manchester United (£5.88 million), and Arsenal (£11.3 million), but above Liverpool (£3.12 million). The women’s side recorded a post‑tax loss of £2.83 million, marginally higher than the £2.73 million loss reported in 2024. The deficit persisted despite a notable surge in commercial revenue, which more than doubled from £1.46 million to £3.34 million. Broadcast income remained static at £267,414, while prize‑money earnings fell by approximately £600,000. On the pitch, Tottenham Women finished the 2024‑25 campaign in 11th place in the Women’s Super League. However, the current 2025‑26 season shows a marked turnaround, with the team sitting fifth with three matches remaining and having nearly doubled their league victories compared with the previous term. Sources indicate that an internal review has repositioned women’s football as a strategic priority for the club, a shift that is expected to be reflected in the forthcoming 2025‑26 accounts.

Manchester United interim manager Michael Carrick strongly criticized the red card decision given to defender Lisandro Martínez during the team's 2-1 loss to Leeds United at Old Trafford. Martínez was sent off in the 56th minute for pulling the hair of Dominic Calvert-Lewin, a decision Carrick described as 'shocking' and one that may prompt an appeal.The red card could result in a three-match ban for Martínez, potentially sidelining him for United's upcoming fixtures against Chelsea, Brentford, and Liverpool. This comes at a critical time as Harry Maguire is also facing a possible suspension for his second yellow card in as many games.Carrick questioned the severity of the red card, stating, 'The arm [is] in the face of Lisandro and he is off balance and grappling. He goes to touch his shirt and gets a red card for it.' He emphasized that the incident did not constitute aggressive behavior, adding, 'It is not aggressive, there is no jolt, no tug.'The manager also expressed concern over another incident involving Noah Okafor's goal for Leeds, suggesting that Dominic Calvert-Lewin impeded Leny Yoro in the buildup. 'The goal, Leny Yoro gets a forearm smash in the back of the head. I don’t know how that doesn’t get overturned,' Carrick remarked.Leeds United's manager, Daniel Farke, reflected on the historic victory, stating, 'I feel tired, relieved, proud of the boys. The first league win here in over 40 years is amazing.'

A federal judge in Miami has dismissed former President Donald Trump’s defamation lawsuit against the Wall Street Journal and News Corp, granting the former president a two‑week deadline to refile the case. Trump’s suit, filed last summer, alleged that a lewd drawing featured in a July 2025 article—purportedly a “bawdy” birthday letter to the late financier Jeffrey Epstein—was fabricated, and that the newspaper published it with actual malice. The complaint also named media mogul Rupert Murdoch, whose News Corp owns the Journal, as a defendant. Judge Darrin P. Gayles ruled that the complaint “fails to adequately allege actual malice,” the legal standard required for defamation actions by public figures. He noted that the Journal had conducted a “significant” inquiry into the authenticity of the drawing and that Trump’s assertion of falsity alone does not prove the newspaper acted with “serious doubts” about the story’s truth. In his opinion, the judge wrote: “Because President Trump has not plausibly alleged that defendants published the article with actual malice, both counts must be dismissed.” He also observed that Trump’s team had not presented evidence of special damages. Under the order, Trump may refile the lawsuit by April 27 with additional proof that the Journal knowingly published false material. A spokesperson for Trump’s legal team confirmed they will pursue a revised filing, emphasizing the administration’s intent to “hold accountable those who traffic in fake news.” The Wall Street Journal and its parent company, Dow Jones, welcomed the decision. A Dow Jones representative said, “We stand behind the reliability, rigor and accuracy of The Wall Street Journal’s reporting.” The dismissal underscores the stringent “actual malice” requirement for defamation suits involving public officials, a threshold that continues to shape media‑law battles in the United States. It also leaves Trump with ongoing litigation against the BBC and other media outlets over separate First Amendment disputes.

Monarch Collective believes that a number of Women’s Super League (WSL) clubs remain “afterthoughts” for their owners, receiving only marginal capital and expertise. Co‑founder Kara Nortman highlighted this concern during a recent interview.Last month, Monarch became the first women’s multi‑sport group by acquiring a minority stake in the Cleveland WNBA franchise, joining an ownership portfolio that already includes NWSL sides San Diego Wave and Boston Legacy, as well as German club Viktoria Berlin.Since establishing Monarch in 2023—four years after launching Angel City FC with Natalie Portman and Julie Uhrman—Nortman has held informal talks with roughly a dozen English clubs, though no deal has yet materialised. She declined to comment on ongoing negotiations with West Ham United’s women’s side, noting that finding the right English partner has proven “challenging”.Recent years have seen a wave of international interest in WSL clubs, yet many prospective investors perceive the women’s teams as a compliance tool for profitability and sustainability mandates rather than a growth engine. In the past twelve months, clubs such as Chelsea, Aston Villa and Everton have sold stakes in their women’s sides to related‑party entities, while US‑based Bay Collective recently secured majority ownership of Sunderland Women in the WSL2.Monarch’s latest $250 million funding round equips it with the capital to act when a suitable opportunity arises. Nortman explained, “If owners truly believe in their women’s team, they should invite us to ‘supercharge’ it with our cross‑sport expertise. If they only want a token boost, that’s a different story.”Beyond capital, Monarch offers advisory services. Nortman recounted a humorous encounter with fans at Crystal Palace, where a supporter asked if she was a “Wag”, prompting a light‑hearted response that underscored the firm’s community‑focused ethos.Reflecting on Angel City’s trajectory, Nortman noted that Monarch initially invested about $1 million to help the club join the NWSL in 2020. Four years later, Angel City was sold to Disney CEO Bob Iger and his wife for a reported $250 million, making it the world’s most valuable women’s franchise.Looking ahead, Monarch is broadening its scope beyond football and basketball, exploring opportunities in cricket and rugby union. The firm recently opened a London office, led by former Manchester City executive Katharine Curran, to deepen its engagement with the UK sports market.

Manchester City is gaining ground on Arsenal in the Premier League standings after a convincing win against Chelsea at Stamford Bridge. Manchester City's victory brings them closer to Arsenal, who suffered a surprising home loss to Bournemouth.In other matches, Tottenham Hotspur's struggles continued as they slipped into the relegation zone following a defeat to Sunderland. Meanwhile, West Ham United thrashed Wolverhampton Wanderers at home.Forest secured a crucial point against Villa, and Liverpool solidified their fifth-place position. In the Football League, Ipswich Town won the East Anglian derby against Millwall, moving into second place with two games in hand.The weekend also saw significant action in League Two, where the top four teams faced each other. Leaders Bromley lost 2-1 to MK Dons, while Cambridge United jumped ahead of Notts County after a 4-0 victory.In Scotland, the top three teams all secured wins, with Hearts maintaining their lead by a single point. Additionally, Barry Glendenning participated in the London Landmarks Half Marathon, and supporters can contribute to his fundraising efforts here.

Recent CDC data reveal a dramatic 1,200% increase in kratom‑related poisonings across the United States over the last ten years, with the most pronounced surge recorded in 2025. Researchers link this rise to the growing presence of 7‑hydroxymitragynine (7‑OH), a synthetically produced compound that mimics kratom’s effects but carries opioid‑like risks. Walter Prozialeck, pharmacology professor at Midwestern University, said the trend was expected, noting that the synthetic alkaloid has entered the market through energy drinks and other products since 2024. Christopher McCurdy of the University of Florida warned that marketing 7‑OH as “enhanced kratom” blurs the line for consumers, turning poison‑control calls into a conflated metric for both natural and synthetic products. By contrast, natural kratom (Mitragyna speciosa)—a Southeast Asian plant used for centuries as a pain reliever—has demonstrated a relatively favorable safety profile in animal and human studies. A 2018 statement from then‑HHS Secretary Brett Giroir rejected the DEA’s push to schedule kratom as a Schedule I substance, citing insufficient evidence of harm. Despite the scientific distinction, several states have moved to implement or propose blanket bans on all kratom products, prompting concern from clinicians and patient advocates. A recent user survey indicated that about 50% of respondents rely on kratom for chronic pain, while roughly 40% use it during addiction recovery. Personal testimonies underscore the plant’s therapeutic role. Jeff Maslan, a 68‑year‑old Californian with severe osteoarthritis, credits kratom with easing opioid withdrawal after multiple surgeries. Similarly, “Steven,” a disabled California resident, describes how kratom eliminated unbearable oxycodone withdrawal symptoms without producing the euphoric “warm fuzzy” feeling typical of opioids. Researchers emphasize that 7‑OH carries genuine opioid hazards, including addiction, severe withdrawal, and respiratory depression that can lead to fatal overdose. In animal models, 7‑OH demonstrated the same respiratory‑depression risk as classic opioids, whereas kratom’s primary alkaloid did not. Prozialeck and colleagues explain that kratom’s pharmacology is more nuanced: it partially activates opioid receptors while also engaging adrenergic and serotonin pathways, resembling a hybrid of a weak opioid and an SNRI‑type antidepressant. This multimodal action likely accounts for its lower euphoric potential and the reported boost in energy among users. Nevertheless, experts caution that kratom is not without risk. Fatal poisonings often involve co‑ingestion of potent opioids such as fentanyl, suggesting that some users may cycle between kratom and stronger substances, raising overdose danger due to reduced opioid tolerance. Additionally, heavy‑metal contamination has been detected in certain kratom batches, though the source—soil, processing, or storage—remains unclear. Given these complexities, the consensus among scholars like Austin Zamarripa (Johns Hopkins) is that natural kratom should remain accessible, while concentrated 7‑OH products merit stricter regulation. “These products may offer meaningful benefits to some individuals, and those benefits could be lost if access is restricted too broadly,” Zamarripa said, urging a differentiated policy approach. As the debate unfolds, patients like Steven worry that a sweeping ban would ignore the nuanced safety profile of the plant. “There’s corn on the cob, there’s high‑fructose corn syrup, there’s whiskey— all derived from corn but fundamentally different,” he remarked, highlighting the need for targeted, evidence‑based regulation rather than a one‑size‑fits‑all prohibition.