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Health Apr 13, 2026

AI Breakthrough: Predicting Bowel Cancer Patients' Response to NHS Drug

Researchers have developed an AI-driven method to predict how patients with advanced bowel cancer w…
Scientists at London's Institute of Cancer Research and the RCSI University of Medicine and Health Sciences in Dublin have announced a new AI-driven approach to identify how patients with advanced bowel cancer will respond to bevacizumab, a drug recently introduced by the NHS. The method uses PhenMap, an AI tool that integrates complex data on the genetic makeup of tumors, allowing researchers to track patterns of how different patients react to the drug. This development aims to spare potentially thousands of patients from being given drugs that would be ineffective in fighting their cancers. In the UK alone, nearly 10,000 cases of advanced bowel cancer are identified every year, with young adults seeing a particular rise in diagnoses. Bowel cancer has the second-highest mortality rate of any cancer, behind only lung cancer. While survival rates can be as high as 98% when caught early, the five-year survival rate for advanced bowel cancer can be as low as 10%. The study tracked 117 European bowel cancer patients who had been treated with chemotherapy and bevacizumab. Researchers identified a group of patients who all had the same gene mutation and were at a high risk of having negative reactions. The scientists behind the tests now hope to expand the number of patient samples and see if the results can be used in treatments for other types of cancer. Anguraj Sadanandam, a professor in stratification and precision medicine at the ICR, said: “Once bowel cancer spreads to other parts of the body, there are very few treatment options available for patients. It is therefore positive that patients can now access the targeted drug bevacizumab on the NHS. However, we know that the majority of patients won’t benefit from the drug, meaning thousands of people in England could be facing unpleasant side effects unnecessarily.” Sadanandam added that while the findings were encouraging, the tool would need to be tested on a larger cohort to be validated. “In future, I hope this approach will lead to a test that can be used by clinicians, to ensure patients receive personalised care that has the highest chance of working against their cancer.”
#bevacizumab #NHS #bowel cancer
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Tv And Radio Apr 13, 2026

Guardian's Weekly Podcast Picks: History Fails, Bizarre News, True‑Crime Thriller, Celebrity Chat and Northern Quirks

The Guardian highlights five new weekly podcasts ranging from a history‑focused series that debunks…
History’s Greatest Fails pairs author Elizabeth Day with historian Dan Jones to explore celebrated historical missteps. After a witty reunion anecdote about their Cambridge days, the duo tackles the myth of Richard III’s villainy and promises a future episode on Henry VIII and Anne Boleyn, dubbed the "Ross and Rachel of early modern history."Strangely follows presenters Poppy Damon and Luke Jones as they plunge into off‑beat news stories, such as the macabre tale of a surgeon who amputated his own legs and the obscure origin of Neil Hopper’s "eunuch‑maker" moniker. The show balances factual depth with a tongue‑in‑cheek tone.Passenger Seat is a slow‑burn true‑crime podcast produced by Pennsylvania writer Tom Joudrey. The inaugural season recounts the 2012 kidnapping of Jennifer Hurst in Ohio, unraveling the puzzling motive behind the crime and the surprising gratitude she later expressed in court.Big Bro With Kid Cudi marks rapper Kid Cudi’s entry into the "celebrity podcast industrial complex". His first interview features Kylie Jenner, who drops the usual Kardashian PR veneer to discuss family dynamics, her upcoming acting role in the film The Moment, and a brief nod to Timothée Chalamet.Northern News reunites comedian Amy Gledhill with Ian Smith to spotlight odd and delightful headlines from the north of England that often slip under the radar. Regular contributors such as Stevie Martin, Alison Spittle and Phil Wang add extra comic flair.
#widely #available #episodes
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Australia News Apr 13, 2026

Australia Urged to Act as Iran War Heightens Nuclear and Climate Threats

The war on Iran has triggered an energy challenge and heightened the threat of nuclear war, combini…
The ongoing conflict in Iran has created a perilous situation where the threat of nuclear war and climate disruption have converged into a single, catastrophic crisis. This crisis will persist long after the war subsides, emphasizing the need for immediate and decisive action. For over a decade, climate change has been recognized not just as an environmental issue but as a fundamental threat to national and global security. The current situation demands that governments conduct thorough risk assessments and treat climate change with the same urgency as military threats. The war on Iran has several alarming features: Unilateral action: The US and Israel launched a large-scale war against a sovereign nation without consulting major allies, creating a diplomatically isolated conflict with no clear exit strategy. Escalation threats: There are credible threats of escalation from both sides, with Donald Trump issuing ultimatums and Iran threatening to target critical infrastructure. Catastrophic miscalculation: The conditions for miscalculation are ripe, with erratic leadership, intelligence failures, and extreme pressure on decision-makers. The conflict has significant implications: Global energy shock: The closure of the Strait of Hormuz has caused an acute global energy shock, with higher oil prices likely to accelerate inflation and economic instability. Climate impact: The war is consuming military resources and political attention, with no climate dividend, and may pressure countries to extend fossil fuel use. Australia, as a regional power and signatory to the NPT, has responsibilities to the international order. The author, Admiral Chris Barrie, calls on the Australian government to take four key steps: Conduct and release a nuclear escalation risk assessment. Use diplomatic channels to counsel restraint. Refuse any form of complicity in nuclear use. Champion de-escalation at the NPT review conference. Australia can play a crucial role in addressing these threats by acting on evidence, speaking plainly about risks, and leading rather than following events.
#nuclear #war #climate
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Sports Apr 13, 2026

Rory McIlroy Sets Sights on New Milestones After Historic Back‑to‑Back Masters Triumph

Rory McIlroy became only the fourth player to win consecutive Masters titles, securing his sixth ma…
Rory McIlroy has joined an elite club by defending his Masters crown at Augusta National, becoming just the fourth golfer ever to win the tournament back‑to‑back. The Northern Irish star edged out world No. 1 Scottie Scheffler by a single shot, marking his sixth major championship and cementing his place in golf history. Speaking after the victory, McIlroy emphasized that the win is a stepping stone, not a final destination. “I just won my sixth major and I feel like I’m in a really good spot with my game and my body,” he said. “I still have things I want to achieve and I want to enjoy the journey.” His parents, Rosie and Gerry, who missed the 2025 ceremony, were present this year, adding a personal dimension to the triumph. “It’s amazing to have them here,” McIlroy remarked, noting that their presence reinforced his motivation and gratitude. Despite the celebratory mood, McIlroy’s performance was far from flawless. He hit only 55% of fairways and recorded 48 of 72 greens in regulation over four rounds. A six‑shot lead after 36 holes evaporated by the 54‑hole mark, and a wayward drive into the trees on the final tee underscored the pressure he faced. Reflecting on the difficulty of the feat, McIlroy admitted, “I don’t make it easy. I used to win by eight shots in my early 20s. This year I realised it’s just really difficult to win the Masters.” He described the moment of uncertainty on the 18th tee as “the greatest stress,” highlighting the thin margin between victory and defeat. Looking ahead, McIlroy signaled that his ambitions extend beyond the Masters. While he plans to take a brief break, he dismissed the notion of a post‑victory lull, stating, “I don’t think I’ll go through that lull of motivation… I still want to enjoy it as well.” With his back‑to‑back Masters titles now secured, the golfer’s next targets remain speculative, but his confidence suggests a continued push for further major victories and possibly a career Grand Slam.
#Rory McIlroy #Masters Tournament #Augusta National Golf Club
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Video Apr 13, 2026

Tehran Controls Initiative, Leaving Washington on Sidelines

The piece underscores that the initiative is managed by Tehran, not Washington, highlighting Iran's…
The report makes clear that the responsibility for the initiative rests with Tehran rather than Washington, emphasizing Iran's decisive position in the issue.
#initiative #hands #tehran
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World Economy Apr 13, 2026

Nigerian Handweavers Keep Aso‑Oke Tradition Alive as Global Demand Soars

Artisans in Iseyin, Nigeria, are preserving the hand‑woven aso‑oke fabric despite rising domestic a…
In the quiet town of Iseyin, about 200 km north‑west of Lagos, shaded courtyards and narrow lanes have become the beating heart of Nigeria’s iconic aso‑oke textile industry. Under makeshift sheds, weavers operate wooden looms that have remained largely unchanged for generations. Recent years have seen a surge in demand for the thick, multicoloured fabric, driven by the Nigerian diaspora and an expanding international appetite for African fashion. Yet the craftsmen and women of Iseyin staunchly oppose the introduction of machines, arguing that the hand‑woven process is essential to the cloth’s distinctive texture and cultural value. The craft now serves as an economic lifeline. Young Nigerians—including university graduates—are flocking to Iseyin to learn the trade, attracted by the promise of a steady income. One such convert, Waliu Fransisco, abandoned a career as a Lagos nightclub singer a decade ago to master the loom. At 34, he says, “I now earn a decent living from weaving aso‑oke and I’m satisfied.” Aso‑oke, literally meaning “cloth from the up‑country,” has become a staple in Nigeria’s fashion scene, appearing in ceremonial attire, contemporary streetwear, and even high‑profile outfits such as the wrapper and shawl worn by Meghan Markle during her 2024 visit to Nigeria with Prince Harry. Traditionally, the fabric was produced from locally sourced cotton or silk, with threads hand‑spun, dyed, and woven in limited colour palettes. Today, most weavers use loom‑ready yarns imported primarily from China, allowing for a broader spectrum of hues while preserving the labor‑intensive hand‑weaving technique. Each loom requires meticulous arrangement of narrow, tightly patterned strips that are later sewn together to form the wider cloth used for garments and accessories. “This is what Iseyin is known for,” says 35‑year‑old weaver Kareem Adeola, echoing the sentiment of a community that views the craft as a direct inheritance from its forebears. As global fashion houses and consumers continue to seek authentic African textiles, the artisans of Iseyin stand at the crossroads of tradition and market opportunity, proving that cultural heritage can thrive alongside modern demand.
#aso-oke #fabric #iseyin
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Politics Apr 13, 2026

Benin Presidential Election: Finance Minister Romuald Wadagni Poised for Victory

Polls have closed in Benin, with Finance Minister Romuald Wadagni expected to win the presidential …
Polls have closed in Benin, with Finance Minister Romuald Wadagni expected to emerge victorious in the presidential election. Wadagni received the endorsement of former President Patrice Talon, who is stepping down after two five-year terms.Nearly eight million voters were eligible to cast ballots on Sunday to choose a successor to Talon. Wadagni, 49, faces a crucial factor in voter turnout after a lackluster campaign affected by voter apathy.In Benin’s largest city, Cotonou, vote counting began late on Sunday afternoon, with provisional results expected on Tuesday. Wadagni is being challenged by Paul Hounkpe, an opposition figure whose campaign has needed help from majority lawmakers to gain parliamentary endorsements.Under Talon, Benin has experienced rapid growth, with gross domestic product (GDP) doubling during his decade in power and numerous infrastructure projects completed. However, a wealth gap remains, and the winner of the vote will also face challenges with insecurity, particularly in the north of the country.The north of Benin has increasingly experienced violence from armed fighters from the Jama’at Nusrat al-Islam wal-Muslimin (JNIM), an al-Qaeda affiliate that has spilled over from the Sahel region.
#Benin #Romuald Wadagni #Patrice Talon
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Politics Apr 13, 2026

Sexual Assault Allegations Threaten Eric Swalwell’s Lead in California Governor Race, Prompt Calls for Withdrawal and Congressional Expulsion

Allegations of sexual assault against Rep. Eric Swalwell have destabilized his frontrunner status i…
Reports of sexual assault allegations against U.S. Representative Eric Swalwell have sent shockwaves through the California gubernatorial race, where recent polls showed him leading a crowded Democratic field seeking to succeed Governor Gavin Newsom.During televised interviews on Sunday, several high‑profile Democratic lawmakers urged Swalwell to drop out of the race and resign from Congress after CNN and the San Francisco Chronicle published accounts from a former staffer and other women alleging misconduct.“What he did is sick and disgusting,” Congressman Ro Khanna told Fox News Sunday, calling for investigations by law‑enforcement and the U.S. House of Representatives.Swalwell has categorically denied the claims as “absolutely false” and indicated no intention to leave the gubernatorial contest. A March poll conducted by Emerson College had him ahead of both Democratic and Republican challengers by several points, underscoring the political stakes.In the wake of the allegations, powerful figures and organizations have begun revoking endorsements, and the Manhattan District Attorney’s office confirmed an active investigation on Saturday.Republican Representative Anna Paulina Luna announced she will file a motion to initiate expulsion proceedings against Swalwell, a step some Democrats say they could support.“This is not a partisan issue,” Representative Pramila Jayapal remarked, emphasizing that the matter “cuts across party lines” and reflects broader concerns about the treatment of women.Democrats have also called for the expulsion of Republican Representative Tony Gonzales of Texas, who faces separate sexual‑misconduct allegations. Both Ro Khanna and Republican Representative Byron Donalds indicated they could back a bid to eject Gonzales and Swalwell from Congress, with Donalds stating, “As far as I’m concerned, both gentlemen need to go home.”California gubernatorial candidate, US Representative Eric Swalwell, appears at a town hall meeting in Sacramento, California, on Tuesday, April 7, 2026 (Rich Pedroncelli/AP Photo)
#Eric Swalwell #California Governor Race #Democratic Party
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News Apr 12, 2026

Trump Orders Immediate US Navy Blockade of Strait of Hormuz After Failed US‑Iran Talks, Raising Ceasefire Concerns

Following the collapse of US‑Iran peace negotiations in Pakistan, President Donald Trump announced …
President Donald Trump declared that the U.S. Navy will commence a blockade of the Strait of Hormuz immediately after peace talks between Washington and Tehran in Pakistan ended without an agreement. In a social‑media post, Trump labeled Iran’s actions as “extortion” and warned that American warships would hunt down and interdict any ship that has paid Iran a toll to traverse the waterway, while also beginning mine‑clearing operations. Iran’s Revolutionary Guard responded that civilian vessels may still cross the strait under “specific regulations,” but any military craft attempting entry would be deemed a breach of the cease‑fire and would be “dealt with severely.” Since the February 28 war launched by the United States and Israel, Iran has effectively taken control of the strategic chokepoint, a route that carries about 20% of the world’s oil and liquefied natural gas shipments. Traffic has now dwindled to a trickle, sending shockwaves through the global economy and raising alarm among Gulf Cooperation Council (GCC) states. Al Jazeera correspondents noted that the rhetoric from the White House has amplified “alarm bells” across the GCC, where leaders had hoped the two‑week ceasefire would evolve into a longer‑term peace framework. Oman’s foreign minister, Badr Albusaidi, urged on social media that the ceasefire be extended and that all parties make “painful concessions” to avoid a return to war. Trump’s statements also included a stark threat: any Iranian forces that fire on U.S. or “peaceful” vessels would be “blown to hell.” He claimed the blockade would involve “other countries” and that the United Kingdom, along with “a couple of other nations,” were dispatching minesweeper vessels to assist – a claim the British government has not confirmed. Domestic criticism emerged quickly. Democratic Senator Mark Warner told CNN he “doesn’t see how blockading the strait will compel Iran to open it,” questioning the strategic logic behind the move. Iran denied U.S. allegations that two of its warships had recently passed through the strait for mine‑clearing, warning that any military vessel attempting such a passage would meet a “strong response.” Tehran officials have floated the idea of instituting a post‑conflict toll system for vessels using the waterway, a prospect that could further entrench Iran’s leverage over global energy flows. Analysts warn that heightened tensions in the Hormuz corridor could push oil prices higher, amplifying inflationary pressures worldwide. As the situation unfolds, mediators continue to press both sides to resume diplomatic talks and avoid a broader escalation.
#strait #iran #trump
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