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George Clooney has publicly denounced Donald Trump's threat to Iran that 'a whole civilization will die tonight', labeling it a war crime. Speaking to 3,000 high school students in Cuneo, Italy, Clooney emphasized that making such threats crosses a line of decency.'Some say Donald Trump is fine,' the 64-year-old actor stated. 'But if anyone says he wants to end a civilization, that's a war crime. You can still support the conservative point of view but there must be a line of decency, and we must not cross it.'The White House responded through communications director Steven Cheung, who retorted: 'The only person committing war crimes is George Clooney for his awful movies and terrible acting ability.'Clooney, a longtime Democratic supporter and donor, has been vocal about his political views for decades. He has previously criticized Trump, who has responded with personal attacks against Clooney.In a statement, Clooney referenced the Genocide Convention and the Rome Statute, defining a war crime as 'when there is intent to physically destroy a nation.' He challenged the administration to defend their stance.The ongoing feud between Clooney and Trump has been marked by public criticisms and counter-attacks. Despite their political differences, Clooney mentioned once being on good terms with Trump before his presidency.

A 47‑year‑old woman who had endured three life‑threatening autoimmune diseases for more than a decade is now living a near‑normal life after an experimental CAR‑T cell therapy reset her immune system at University Hospital Erlangen in Germany.Before the procedure she had exhausted nine different treatments with no lasting benefit, relying on daily blood transfusions and continuous anticoagulation to manage her illnesses.Within weeks of the infusion, doctors observed rapid improvement in all three conditions—a world‑first outcome. She has remained in treatment‑free remission for 14 months and has largely returned to everyday activities.Prof Fabian Müller, who led the team, called the speed and depth of the response “remarkable” and said the therapy “significantly improved her quality of life.” He emphasized that clinical trials are required to determine how durable the effect is and whether it can help other autoimmune patients.The patient suffered from three distinct disorders: autoimmune haemolytic anaemia (AIHA), where rogue immune cells destroy red blood cells; immune thrombocytopenia (ITP), which depletes platelets and raises bleeding risk; and antiphospholipid syndrome (APS), which promotes dangerous blood clots. All three stem from malfunctioning B‑cells.With no conventional options left, doctors turned to CAR‑T therapy, a technique that has revolutionised treatment for certain cancers. They harvested her white‑blood cells, isolated the T‑cells, engineered them to recognise the CD19 protein on B‑cells, and reinfused the modified cells.The engineered T‑cells swiftly eliminated the pathogenic B‑cells. She received her last blood transfusion a week after treatment and was able to perform routine tasks within two weeks. Follow‑up tests showed a reconstituted, healthy B‑cell population, suggesting an immune reset. The findings were published in the journal Med.She still exhibits a mildly low white‑cell count and slightly elevated liver enzymes, which researchers attribute to the cumulative impact of prior therapies rather than the CAR‑T product.Rheumatology expert Prof Ben Parker of Manchester University NHS Foundation Trust described the case as encouraging, noting that “the prolonged response off normal therapy suggests there has been an immune reset.” However, he warned that case reports alone cannot confirm efficacy and highlighted ongoing trials for lupus, myositis, multiple sclerosis, systemic sclerosis, vasculitis, and other autoimmune conditions.

Argentina's congress has approved a bill promoted by President Javier Milei that authorizes mining in ecologically sensitive areas of glaciers and permafrost, sparking widespread environmental protests. The bill, which was already approved by the senate in February, will make it easier to mine for metals such as copper, lithium, and silver in frozen parts of the Andes mountains.The chamber of deputies approved the amendment with 137 votes in favor, 111 against, and three abstentions after nearly 12 hours of debate. Environmentalists argue that the legislative changes will weaken protections for crucial water sources, with thousands protesting outside parliament, holding banners with slogans such as “Water is more precious than gold!” and “A glacier destroyed cannot be restored!”Seven Greenpeace activists were arrested earlier in the day after scaling a statue outside parliament and unfurling a banner urging lawmakers “not to betray the Argentine people”. The passage of the amendment is a new coup for Milei, who pushed through looser labor laws in February despite repeated street protests.Environmental activists, such as Flavia Broffoni, argue that there is no possibility of creating a 'sustainable mine' in a periglacial environment. Argentina has nearly 17,000 glaciers or rock glaciers, with glacial reserves in the north-west shrinking by 17% in the last decade due to climate change.Milei, a free-market radical who does not believe in human-made climate change, says the bill is necessary to attract large-scale mining projects. The Central Bank of Argentina estimates that the country could triple its mining exports by 2030. Supporters argue that the bill will provide legal certainty and clear definitions, while critics, such as Enrique Viale, warn that it threatens the water supply for 70% of Argentinians.

Europe is undergoing a significant transformation in its relationship with the US, marked by a growing desire for independence and a shift away from Trump's aggressive policies. The recent crisis in the Middle East, where Trump's threat to annihilate Iranian civilisation was temporarily called off, has been a turning point in this journey. Initially, many European leaders had tacitly supported the US and Israeli attack on Iran, driven by a desire for a transatlantic detente and antipathy towards the Iranian regime. However, as the war escalated, Europe's stance began to shift, with countries like Italy, Poland, and France taking steps to distance themselves from Trump's policies. The cooling of European support for the war has taken various forms, including Italy denying US warplanes permission to use an airbase in Sicily, Poland refusing to send Patriot air defence systems to the Middle East, and France rejecting overflight rights and opposing a US-sponsored resolution at the UN security council. This shift in European policy is driven by a number of factors, including the realisation that the war has been a windfall for Russia, through higher oil prices and a depletion of air defence interceptors available to Ukraine. European leaders have also been reminded that the erosion of international law is bad news for the world, Europe included. As Europe finds its footing in distancing itself from Trump, it may also find its voice. Europe's diplomatic role in the Iranian nuclear file in the early 2000s grew out of its opposition to the Iraq war. Today, the same dynamic could unfold, with Europe promoting a permanent end of hostilities and a multilateral initiative in the region. The proposal by a group of European, Gulf, and Asian countries to contribute to ensuring safe passage through the strait of Hormuz was originally aimed at placating Trump. Europeans then backed a UN-led fertiliser corridor to prevent a food crisis in the global south. The UK is also leading a coalition of more than 40 countries seeking to reopen the strait once the US and Israel definitively end their offensive. If a sustainable reopening of Hormuz succeeds, it could eventually extend to a new nuclear agreement, a non-aggression pact between the US and Iran, and a similar one between Israel and Iran – including Lebanon. It could involve the release of Iranian funds frozen abroad to rebuild infrastructure destroyed by US and Israeli attacks, and the selective lifting of EU and US sanctions.

Pakistan's diplomatic efforts culminated in a two-week ceasefire between the US and Iran, agreed upon just hours before US President Donald Trump's deadline to destroy Iran's 'civilisation'. The ceasefire was announced by Trump on his social media platform, Truth Social, and confirmed by Iranian Foreign Minister Abbas Araghchi.The breakthrough was facilitated by Pakistani Prime Minister Shehbaz Sharif and Field Marshal Asim Munir, who engaged in extensive diplomacy with both sides. Sharif publicly announced the ceasefire, inviting both delegations to Islamabad for further negotiations. The talks are expected to begin on Friday, potentially involving a US delegation led by Vice President JD Vance.The conflict, which began on February 28, had killed over 2,000 people in Iran and disrupted roughly a fifth of the world's oil supplies. Pakistan's role as a mediator was seen as a significant diplomatic achievement, with both Washington and Tehran acknowledging its efforts.The ceasefire is not a peace deal, and key differences remain unresolved, including Iran's uranium enrichment and the Strait of Hormuz. However, analysts view Pakistan's role as a major shift in its diplomatic efforts, positioning itself at the centre of a significant diplomatic initiative.

The recent ceasefire between the United States and Iran may provide temporary relief, but the oil crisis triggered by their conflict is far from over. After 40 days of fighting, the two nations agreed to a two-week ceasefire, with negotiations set to begin in Pakistan's capital, Islamabad.One of the key points in Iran's 10-point proposal is allowing shipping to resume through the Strait of Hormuz, a critical waterway through which 20 percent of the world's oil and gas is shipped during peacetime. The strait has been effectively closed since the start of the war, causing global oil and gas prices to soar.Following the announcement, oil prices dropped to $92 on Wednesday, down from over $110 for much of the war. However, delays in restarting production and transport mean the energy crisis is far from over. For ships to continue operating, they need certainty about security during the next two weeks of the ceasefire.Even with the waterway reopened, it will take weeks for large oil tankers – now scattered thousands of miles away – to return to the Gulf to collect the millions of barrels sitting in large reservoirs. With very few tankers able to load or unload and their onshore storage full, producers began shutting wells, causing regional oil output to plummet despite efforts to reroute limited volumes via overland pipelines.Economists warn that the true impact on grocery bills will likely persist throughout 2026 and into 2027. Additionally, it will take years for the Gulf energy industry to repair facilities damaged or destroyed during the war.Shipping data shows that combined exports from Iraq, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates fell from 469 million barrels in February to 263 million barrels in March – a decline of 206 million barrels, or 44 percent. Iraq's crude exports have been hit the hardest, falling 82 percent from 94m barrels in February to 17m in March.The 206 million barrels of Gulf oil lost since the start of the war would fill approximately 103 Very Large Crude Carriers (VLCCs), the workhorse supertankers of the global energy trade. A single VLCC stretches nearly 330 metres (1,080 feet) in length, nearly the same height as the Eiffel Tower in Paris.To put that in more practical terms, if you drove a pick-up truck that averages 24 miles per gallon (or 10 litres per 100km), one barrel of crude oil would carry you about 730km or 450 miles. That is about the distance from New York City to Cleveland, Ohio.For much of the war, oil has traded above $100 per barrel, hitting a peak of nearly $128 on April 2. The value of 206 million lost export barrels at various oil prices is significant, with Brent crude being the global benchmark.

US Defense Secretary Pete Hegseth announced on Wednesday that the United States had achieved a "decisive" military victory over Iran, claiming the Iranian missile programme has been "functionally destroyed." Speaking alongside General Dan Caine, chairman of the Joint Chiefs of Staff, Hegseth described the operation—codenamed Operation Epic Fury—as a "historic and overwhelming" triumph that met every objective, including the dismantling of Iran’s navy, air‑defence systems and missile‑production capability. The declaration came a day after President Donald Trump stepped back from a threatened full‑scale assault on Iran, just two hours before a self‑imposed deadline for Tehran to reopen the blockaded Strait of Hormuz. The resulting cease‑fire agreement stipulates that Iran will not possess a nuclear weapon and that the United States will monitor the country’s enriched uranium stockpiles. While Hegseth emphasized that "they can still shoot here and there, but that would be very unwise," he also warned that US forces will remain in the region to ensure compliance with the two‑week cease‑fire and to oversee the safe transit of vessels through the strategic waterway. Iran’s response was equally emphatic. The Supreme National Security Council, cited by IRNA, congratulated the Iranian people on a "victory" and urged perseverance until the details of that victory are finalized. The council highlighted Iran’s alliances with the so‑called "axis of resistance" in Lebanon, Iraq, Yemen and occupied Palestine, claiming the coalition has delivered blows to the enemy over the past 40 days. At the same briefing, General Caine confirmed that US military objectives in Iran have been met, but framed the cease‑fire as a "pause" rather than a permanent end to hostilities, noting that forces remain ready to resume combat if necessary. In parallel diplomatic developments, a senior Iranian official told Reuters that Tehran could reopen the Strait of Hormuz on Thursday or Friday, contingent on a cease‑fire framework being reached ahead of a scheduled US‑Iran meeting in Pakistan. The closure of the strait has previously disrupted global oil and gas markets, making its reopening a critical economic signal. Trita Parsi, vice‑president of the Quincy Institute for Responsible Statecraft, told Al Jazeera that President Trump needed an exit from a war he described as "an absolute disaster" and that the next two weeks are "crucial" for any genuine diplomatic opening, though he cautioned that the situation is not yet resolved. Analysts note that the cease‑fire’s success will hinge on Iran’s willingness to allow unfettered navigation through the Strait of Hormuz and on US verification of Iran’s uranium holdings. The coming fortnight will test whether the declared victory translates into lasting stability in a volatile region.

Assam, India – Under the sweltering April sun, Akram Ali stood amid the rubble of his four‑room house, a home he had built over 45 years ago. The demolition, part of a government‑led bulldozing operation on March 14, turned his residence into a pile of debris.Bulldozers descended on Islampur, a Muslim‑majority neighbourhood on the outskirts of Guwahati, and for four hours razed homes across 177 hectares (437 acres). The sweep rendered 400 families homeless, including Ali, who now lives in a tarpaulin shanty a few kilometres from his former home.Ali, a daily‑wage worker, told Al Jazeera that despite identifying as Goriya – “son of the soil” – his house was destroyed. The Goriyas are an Assamese‑speaking Muslim community traditionally settled in the tea‑belt region. In 2022, the ruling Bharatiya Janata Party (BJP) officially recognised the Goriya, along with four other Muslim sub‑groups, as “Indigenous” to Assam.While this designation has afforded the Indigenous Muslims a degree of cultural safety, it has not shielded them from the state’s aggressive land‑clearance drives. Ali questioned the distinction, asking, “Weren’t our homes demolished because we are Muslims?”Muslims make up more than a third of Assam’s 31 million residents, according to the 2011 census. Of these, roughly 6.3 million are Bengali‑speaking “miyas,” often labelled “outsiders,” while about 4 million belong to Indigenous groups like the Goriya.The BJP, led nationally by Prime Minister Narendra Modi, has been courting the Indigenous Muslim vote ahead of the April 2026 state elections, where it seeks a third consecutive term after governing since 2016. Chief Minister Himanta Biswa Sarma, who has spearheaded the party’s crackdown on “miyas” since 2021, claims the government will “never target” Indigenous Muslims.Political analyst Bonojit Hussain explains that the BJP’s outreach serves two purposes: softening its communal image and capturing decisive vote blocks in constituencies where Indigenous Muslims and Hindus together decide the outcome. In seats such as Nalbari, where Indigenous Muslims account for over 25 % of the electorate, and Barkhetri, with roughly 80,000 Muslim voters, the community’s support can swing the result.Upper Assam, a region with a strong Assamese‑speaking identity, is especially critical. Journalist Firoz Khan notes that Indigenous Muslims influence the outcome in seven or eight of the 39 seats there, prompting the BJP to temper its overtly anti‑Muslim rhetoric in the area.Despite the party’s overtures, many Indigenous Muslims remain skeptical. Moinul Islam, spokesperson for the rights group Sadou Asom Goria Jatiya Parishad, warned that the BJP’s broader anti‑Muslim policies—evictions, voter‑list objections, and alleged deportations—are unlikely to win their votes.Earlier in 2025, similar demolition drives displaced hundreds of Goriya families in Lakhimpur and Golaghat districts, and a systematic campaign to challenge Muslim names on electoral rolls further strained relations.BJP spokesman Kishore Upadhyay dismissed the allegations as “malicious, biased and politically motivated,” but Indigenous groups argue the pattern signals an attempt to erase their cultural legacy.Recent actions by the state government reinforce this perception. Chief Minister Sarma renamed the only medical college in Barpeta—previously bearing the name of Goriya freedom fighter Fakhruddin Ali Ahmed—arguing that institutions should reflect their geographic location. Critics view the move as symbolic of a broader effort to marginalise Muslim contributions to Assam’s history.In December 2025, Sarma also proposed dropping the hyphen in “Sankar‑Azan,” a name that celebrated the syncretic legacy of 15th‑century polymath Srimanta Sankardev and 17th‑century Sufi saint Azan Peer. Communist Party member Isfaqur Rahman warned that such revisions reflect a “slow erasure of Assamese Muslim heritage.”For Ali, the demolition has hardened his political stance. “After being evicted, the chief minister called us illegal immigrants and broke our backs by destroying our homes,” he said. “We are the new miyas.”

Washington, D.C. – President Donald Trump declared a two‑week ceasefire with Iran on Tuesday, just hours after threatening a massive attack on the country. The pause will allow Iran to reopen the strategic Strait of Hormuz while both sides negotiate a longer‑term settlement. Republican Senator Lindsey Graham, a noted Iran hawk, welcomed the diplomatic move but stressed extreme caution. He praised the “hard work” of negotiators but warned that any agreement must be scrutinized, noting that Iran’s 10‑point plan reportedly offers sanctions relief and permits Tehran to retain control of the strait. Graham also warned that Iran must not be rewarded for its earlier attacks on the strait, writing on X: “We must remember that the Strait of Hormuz was attacked by Iran after the start of the war, destroying freedom of navigation. Going forward, it is imperative Iran is not rewarded for this hostile act against the world.” Democratic senators, while relieved that U.S. forces would be out of immediate danger, seized the moment to demand accountability. Senator Ruben Gallego said, “Stopping war is good… we can criticize why we got into this war, the illegality of it and hold the Trump admin accountable. But right now I am relieved.” Other Democrats, including Senator Ed Markey and Congresswoman Alexandria Ocasio‑Cortez, warned that the ceasefire does not erase the fact that the conflict was launched without congressional authorization and that targeting civilian infrastructure may constitute war crimes. Ocasio‑Cortez wrote, “The President has threatened a genocide against the Iranian people… launched a massive war… without reason, rationale, nor Congressional authorization – which is as clear a violation of the Constitution as any.” Critics on the right, such as far‑right activist Laura Loomer and commentator Mark Levin, dismissed the truce as a temporary pause, predicting the war will resume. Loomer warned, “The negotiation is a negative for our country… I don’t know why people are acting like this is a win.” Levin added, “This enemy is still the enemy; they’re still surviving.” The conflict, which began on February 28 without a congressional war declaration, has already seen high‑profile strikes, including an attack that the article claims killed Iranian Supreme Leader Ayatollah Ali Khamenei and a devastating strike on a girls’ school in Minab that killed over 170 civilians, mostly children. Economically, the closure of the Strait of Hormuz earlier in the war sent oil and gas prices soaring, underscoring the strategic importance of the waterway. Senator Chris Murphy (D) warned that allowing Iran to control the strait would be a “history‑changing win” for Tehran. Across the aisle, lawmakers agree that the ceasefire is not a clean slate. Advocacy director Raed Jarrar of DAWN urged an immediate congressional investigation into the war’s origins, funding, and accountability for civilian casualties. As the two‑week pause unfolds, U.S. officials and legislators will closely monitor negotiations, with the broader debate over war powers, constitutional authority, and potential impeachment of President Trump remaining front and center in Washington.