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Scientists have made a groundbreaking discovery, identifying a distinct 'neural fingerprint' produced by psychedelic drugs in the human brain when users experience their mind-altering effects.This breakthrough finding emerged from a comprehensive study that combined 11 brain imaging datasets from around the world, involving over 500 brain scans from 267 people in five countries. The research focused on five psychedelic substances: LSD, psilocybin, DMT, mescaline, and ayahuasca.The study revealed that these substances have a shared impact on the brain's behavior, dissolving the usual hierarchy of brain systems and flattening the hierarchy, which may underlie the raw access to one's own consciousness that some people describe during psychedelic experiences.Dr. Danilo Bzdok, a senior author on the study from McGill University in Montreal, Canada, explained that all five drugs change brain function in common ways, despite some differences in how they alter brain activity. The most striking effect was stronger communication between brain networks that engage in higher-level thinking and more primitive networks linked to vision and sensation.The research, published in Nature Medicine, provides a solid foundation for psychedelic research, which is crucial if these drugs are to become widespread therapies for mental health conditions such as depression, schizophrenia, and post-traumatic stress disorder.Dr. Emmanuel Stamatakis, a senior co-author on the study from the University of Cambridge, emphasized the importance of large-scale, coordinated evidence in the field of psychedelic research, which is moving quickly and needs to mature responsibly.

At Augusta National, Justin Rose’s name appears twice on the bronze winner’s list beside the victories of Sergio García (2017) and Rory McIlroy (2025) – both wins coming after playoffs that Rose lost. Only Ben Hogan shares the dubious distinction of losing two Masters playoffs, though Hogan later won the tournament twice outright.Rose’s record also includes a second‑place finish in 2015, four strokes behind Jordan Spieth. The only player with more runner‑up finishes without ever winning is Tom Weiskopf, who was second four times in seven years.Now 45 years old and entering his 21st Masters, Rose cannot predict if he will ever get as close again as he did last year, when McIlroy’s birdie putt on the 18th sealed a one‑stroke playoff defeat.“When you realise you’re that close, you can taste the victory,” Rose says. “I lived it as if I’d won, but without the real positive emotion – I sensed everything.” He acknowledges the mental rehearsal of the “what‑if” scenario while maintaining that he “did everything he could” and can live with the result.Rose explains his mental formula: “You can’t make a major win too important in the moment,” because a career inevitably includes “a little bit of heart‑ache and heartbreak.” He believes that to win, a player must also be prepared to be on the losing side.Despite the setbacks, Rose feels he has already demonstrated the necessary skill set. “I’ve pretty much done what it takes to win. I just haven’t walked over the line,” he asserts, emphasizing that he does not feel the need to change his approach.Recent form offers optimism. Earlier this year Rose set a new course record at Torrey Pines and became the first player in 71 years to win the Farmers Insurance Open wire‑to‑wire. He notes that eight players have captured the Masters after finishing second the previous year, suggesting his odds improve when the field is considered.Rose is also mindful of external narratives. “People are wishing me well and thinking it’s my year,” he admits, adding that he must manage expectations and craft his own story rather than buying into others’ predictions.

A Guardian investigation has shed light on the dark reality of child sex trafficking on Facebook and Instagram, prompting a landmark lawsuit against Meta. The tech giant has been fined $375m in a New Mexico court case, highlighting its failure to prevent criminal exploitation on its platforms.The investigation, led by reporter Katie McQue, began with a tip-off about surging child sexual abuse trafficking in the US. It uncovered evidence of traffickers using Facebook Messenger and private Instagram accounts to target, groom, and exploit children. Meta was found to be struggling to prevent these crimes, despite warnings from experts and law enforcement.The probe involved extensive research, including analysis of court documents and interviews with former Meta contract workers. These workers reported that their efforts to flag and escalate possible child trafficking often went unaddressed, and harmful content was rarely removed.The investigation's findings were published in April 2023, revealing how Facebook and Instagram had become marketplaces for child sex trafficking. The case was cited in a US supreme court amicus brief, and New Mexico's office of the attorney general filed a lawsuit against Meta for failing to protect children.The lawsuit went to trial, and Meta lost the court battle in March, being ordered to pay $375m in civil penalties. The company has said it will appeal the ruling, maintaining its stance on protecting teens online.This case marks a significant milestone in the ongoing scrutiny of social media platforms' role in combating child exploitation. Meta faces further trials, including one with a coalition of 33 attorneys general alleging the company designed features that 'purposefully addict children and teens.'

Italy's World Cup qualifying playoff woes continued as they lost to Bosnia on penalties, following a 1-0 win over Northern Ireland. Alessandro Bastoni's first-half red card in the Bosnia game was pivotal.Bastoni had been jeered by fans in away games for Inter Milan due to his actions in February's Derby d'Italia against Juventus, where he got Pierre Kalulu sent off. He apologized for his behavior, calling it 'really ugly'.Inter Milan bounced back from their slump with a convincing 5-2 win over Roma, Lautaro Martínez scoring. Marcus Thuram and Hakan Calhanoglu also shone, with the latter scoring a goal of the season contender from 30 yards.The win eased Inter's nerves ahead of Serie A title contention, keeping their lead intact. Alessandro Bastoni received a standing ovation when substituted, with fans chanting his name.

The recent conflict between Israel and Iran has highlighted the consequences of Israeli Prime Minister Benjamin Netanyahu's promise of an 'easy' war. When Netanyahu met with US President Donald Trump at Mar-a-Lago in December, he came with an appeal and a subtle inducement.Netanyahu had suggested a final benefit to Trump: defeating Iran would allow Israel to wean itself off its massive reliance on US military aid. However, the reality of the conflict has been far from easy, with Iran's resilient regime and the ongoing Middle East war showing no signs of abating.The conflict has also had significant implications for global diplomacy, with Emmanuel Macron reflecting a widespread view that US and Israeli strikes on Iran would not provide a durable solution to Tehran's nuclear program. The war has undermined Nato and potentially emboldened China, Russia, and North Korea.The conflict has also led to a decline in support for Israel globally, with polls showing a decline in support for Israel across the political spectrum in the US, particularly among Democrats and young voters. A Gallup survey released recently showed that Americans are more sympathetic to Palestinians than Israelis for the first time since Gallup began measuring that question in 2001.

President Donald Trump’s recent proclamation that Iran must reopen the Strait of Hormuz or face a combined "Power Plant Day" and "Bridge Day" has thrust senior U.S. officers into a stark ethical quandary: obey a presidential directive that could breach international law, or risk court‑martial for insubordination. In a post on his Truth Social platform, Trump warned that failure to comply would result in an unprecedented strike on Iran’s civilian energy infrastructure, a move that legal scholars agree would amount to a war crime against 93 million civilians. Two former judge‑advocate general officers, Margaret Donovan and Rachel VanLandingham, emphasized that such rhetoric, if acted upon, would place service members on a “path of no return,” directly contradicting the extensive legal training that defines permissible orders. Historical precedent underscores the gravity of the situation. During the Vietnam War, officers who participated in the My Lai massacre were ultimately held accountable, with the court rejecting the “just following orders” defence as the orders were deemed “palpably illegal.” Professor Charli Carpenter of the University of Massachusetts Amherst notes that while many troops can identify manifestly unlawful commands in surveys, translating that awareness into real‑time refusal is far more challenging, especially when the military culture heavily emphasizes obedience to the chain of command. Since assuming office, Defense Secretary Pete Hegseth has reshaped the Pentagon’s legal advisory structure, dismissing senior JAG officials and dismantling the Civilian Harm Mitigation and Response unit created under the previous administration. Consequently, service members now rely on a “GI rights hotline,” whose usage has reportedly surged under the current leadership. Beyond conventional strikes, Trump’s escalating rhetoric has raised alarms about the potential use of nuclear force. Under U.S. protocol, the president alone can initiate a nuclear launch, with the “nuclear football” – a briefcase containing strike options and authentication codes – handed to a close aide. The only safeguard is for senior commanders to deem such an order illegal, a step that experts fear may never occur. Former Joint Chiefs Chairman Gen. Mark Milley, during the previous administration, reportedly instructed senior officers to stay involved in any nuclear decision due to concerns about Trump’s volatility. Nuclear weapons scholar Jeffrey Lewis now warns that confidence in any contemporary intervention is essentially nonexistent, citing Trump’s pattern of purging dissenting military personnel. As the deadline looms, the United States faces a precarious balance between upholding international humanitarian law and navigating a command structure that may be unwilling or unable to challenge the commander‑in‑chief’s most extreme directives.

Donald Trump has repeatedly framed inflation as a "hoax" and declared that he has "won affordability," yet independent analyses reveal that his touted initiatives deliver only marginal relief for most Americans.One of his most publicized programs, the TrumpRX prescription‑drug platform, lists just 61 medications out of the thousands needed nationwide. Moreover, price comparisons show that a medium dose of Wegovy costs $349 on TrumpRX, while the same dose sells for $163 in Japan and $198 in Germany. Similar gaps appear for diabetes drug Xigduo and autoimmune medication Xeljanz, which are significantly cheaper abroad.The website markets itself as a solution for uninsured, cash‑paying patients, but it does nothing for the roughly 85 % of Americans who already have prescription coverage.On housing, Trump’s executive order banning Wall Street firms from buying single‑family homes is unlikely to move the needle. Institutional investors own only about 2 % of such homes, while the nation faces a shortage of roughly 4.7 million units, according to Zillow. The ongoing war in Iran has also pushed mortgage rates higher, further straining affordability.Gasoline prices have surged since the Iran conflict began, climbing to an average of $4.10 per gallon – a 37 % increase from the pre‑war level of $2.98.Food costs tell a similar story. The Consumer Price Index shows a 3.1 % rise in overall food prices from February 2025 to February 2026, with coffee up 18.4 %, beef up 14.4 %, and fresh vegetables up 5.4 %. Tariffs championed by the administration have contributed to these hikes.International bodies echo domestic concerns. The OECD projects U.S. inflation to exceed 4 % this year, largely driven by the Iran war, a level higher than the 3 % rate recorded at the end of the Biden administration.Trump also claims to have eliminated taxes on overtime and Social Security benefits. In reality, overtime earnings are still subject to federal income tax on the base wage and to full Social Security and Medicare payroll taxes. Only the overtime premium enjoys a partial tax break. Likewise, more than half of Social Security recipients will continue to owe income tax on their benefits, contradicting the administration’s “no‑tax” narrative.Other initiatives, such as the “Trump Accounts” child‑savings program, provide a one‑time $1,000 seed deposit and allow families to contribute up to $5,000 annually. While beneficial for affluent households, the scheme offers limited assistance to families living paycheck‑to‑paycheck.Policy decisions have also raised costs for vulnerable groups. By opposing extensions of Obamacare subsidies, average health‑care premiums have risen by over 20 % for more than 20 million people. Simultaneously, proposed cuts to LIHEAP threaten heating and cooling assistance for roughly 6 million low‑income households.In sum, Trump’s affordability rhetoric serves more as political branding than substantive economic relief. The modest scope of his programs and the persistence of rising prices suggest that most working‑class Americans will see little improvement in their day‑to‑day expenses.

Two weeks after the United States and Israel entered a direct conflict with Iran, the White House faced mounting criticism that the war would drive up fuel costs and anger voters. Former President Donald Trump attempted to calm concerns on Truth Social, noting that the United States is the world’s largest oil producer and that higher prices translate into higher revenues for American companies. Now, five weeks into the hostilities, the reality is becoming clear: defense contractors and oil companies are the primary beneficiaries of the escalating energy market. The Department of Defense announced that Boeing will partner with Lockheed Martin to triple U.S. production of missile seekers, a move that sent Lockheed Martin’s stock up 25% since the start of the year. The announcement also lifted Boeing’s share price, underscoring how wartime procurement is boosting aerospace valuations. At the same time, Iran’s continued blockade of the Strait of Hormuz—through which roughly one‑fifth of global oil and gas flows—has pushed U.S. crude from $65 to over $110 per barrel in just a month. Pump prices have mirrored this surge, breaking the $4‑a‑gallon barrier for the first time since 2022. Oil majors have responded with sharp stock gains; ExxonMobil, Shell and Chevron have each risen more than 20% year‑to‑date. According to market‑research firm Rystad Energy, U.S. oil producers stand to earn an additional $63 billion as barrels trade above $100. “Oil prices in March have been materially higher than anyone expected, delivering a windfall for the vast majority of U.S. energy companies,” said Leo Mariani, senior analyst at Roth Capital Partners. The last comparable price shock occurred in 2022 after Russia’s invasion of Ukraine, when U.S. gasoline peaked at $5 per gallon and inflation surged to 9%. That episode generated $916 billion in global oil‑and‑gas profits, with U.S. firms accounting for $281 billion. Chevron’s subsequent $75 billion stock‑buyback program—seven times its prior year’s amount—illustrates how quickly companies can translate price spikes into shareholder returns. Research by economists Gregor Semieniuk and Isabella Weber revealed that in 2022, 50% of oil‑company profits went to the top 1% of Americans, while the bottom half of the wealth distribution captured just 1% of those gains. Analysts warn that the current conflict could generate even larger windfalls because it has damaged actual production capacity in the Middle East, not merely reshuffled supply. “You’re benefiting a lot more from higher prices than you are from lost production,” Mariani noted, emphasizing the outsized profit potential. Even if hostilities cease, restoring pre‑conflict output in the region may take months, prolonging the supply crunch. As senior fellow Clay Seagle of the Center for Strategic and International Studies explains, the current situation differs from 2022: “Now we’re dealing with a much more severe supply event because the oil has been actually removed from the market.” Prolonged high prices could eventually curb demand, as consumers and businesses seek alternatives—a shift seen after the 1970s oil shocks when the U.S. moved away from oil‑generated electricity. Nonetheless, many sectors remain vulnerable: diesel, a key fuel for trucks and aircraft, has risen 40%, and airline stocks such as United and American have fallen more than 15% since the year began. Moreover, disruptions to liquefied natural gas (LNG) production threaten fertilizer supplies essential for agriculture. Semieniuk cautions that “we’re approaching the kinds of disruption levels we saw in 2022, and with that, the kinds of profits that we saw there. If this takes longer, it’s going to surpass that.”

The cost of living crisis in the UK has become a persistent reality for many low-income families, who are struggling to make ends meet. The situation has worsened due to the ripple effects of the war in Ukraine, with companies expected to raise prices rapidly in the coming months.The author, Ella Michalski, is part of Changing Realities, a collaboration of parents and low-income families from across the UK. She shares her personal experience of struggling to get by, with her family relying heavily on their car due to her daughters' complex needs. The financial circumstances of her family have not significantly improved in the past five years, despite her partner working.The article highlights the need for more support from the government, particularly for families with dependent children. The recent abolition of the two-child benefit cap and the rise in the minimum wage are seen as positive steps, but more needs to be done to address the root causes of poverty. The author also calls for changes to universal credit, including ending the punishing five-week wait for a first payment.The government's crisis and resilience fund (CRF) is seen as a step in the right direction, but its accessibility and effectiveness are concerns. The author argues that the government needs to target cost of living support at those who need it most, with a recognition that families with dependent children need more support.