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The recent ceasefire talks between the United States and Iran have ended without a breakthrough, with Iran's chief negotiator, Mohammad Bagher Ghalibaf, blaming the US for the failure of the talks held in Islamabad, Pakistan. The talks, which were the first direct engagement between the two countries at this level since the 1979 Iranian Revolution, exposed deep divisions on core issues.The US framed the lack of a breakthrough primarily around Iran's alleged refusal to meet its core demand: a firm commitment not to develop nuclear weapons. US Vice President JD Vance said Washington had made its 'red lines' clear and presented what he described as a 'final and best offer'. However, Iran downplayed expectations and blamed the US for making unreasonable demands.The main sticking points between Tehran and Washington are:Iran's nuclear programme: The US wants a clear and enforceable commitment that Iran will not develop nuclear weapons – or even the capability to do so quickly. Iran has consistently rejected accusations that it seeks to build nuclear weapons but said it is willing to negotiate limits on its nuclear activities if sanctions are removed.Strait of Hormuz: Who gets to control this strategic waterway, through which almost all of the oil and natural gas exports from the Gulf nations pass, has become a major flashpoint. Iran has floated the idea of charging transit fees to allow ships to pass through the strait, while the US is adamant the strait is reopened free of any tolls.The near shutdown of shipping through the strait has sent global energy prices soaring with many countries, especially in Asia, forced to implement unprecedented austerity measures to soften the impact of fuel shortages. Experts said the near-closure of the strait has caused the worst economic shock since the 1973 oil embargo.

The Israeli Defense Forces launched a series of raids throughout the occupied West Bank during the night, marking a heightened security push in the area.According to reports, the operations spanned multiple locations, reflecting ongoing tensions and the Israeli military's focus on curbing perceived threats within the territory.While specific details of the raids remain limited, the actions underscore the persistent volatility in the region and the broader implications for Israeli-Palestinian relations.

Saudi Arabia has returned its East‑West oil pipeline to full operational capacity, enabling the transport of approximately 7 million barrels of crude per day after a series of attacks disrupted flow earlier this week. In a statement released on Sunday, the Ministry of Energy praised the swift repair work, noting that the turnaround demonstrates the high operational resilience and crisis‑management efficiency of Saudi Aramco and the broader national energy system. The ministry also confirmed that production at the Manifa oilfield—situated off Saudi Arabia’s eastern coast—has been restored to its full capacity of about 300,000 barrels per day (bpd). Efforts continue at the inland Khurais oilfield, which is still recovering from a loss of roughly 300,000 bpd. Earlier reports from the Saudi Press Agency indicated that attacks on a pumping station along the East‑West pipeline had cut daily output by 700,000 bpd. Simultaneous assaults on the Manifa and Khurais fields were said to have reduced combined capacity by 600,000 bpd. No party was identified as responsible for the attacks. The East‑West pipeline, linking the prolific Abqaiq field in the east to the Red Sea port of Yanbu, has become a vital conduit for international oil supplies, especially as Iran’s effective closure of the Strait of Hormuz has choked off about 20% of global oil shipments, driving up energy prices worldwide. Despite a fragile cease‑fire announced on Tuesday between the United States and Iran, maritime traffic through the strait remains severely limited. Data from S&P; Global show that only 22 vessels with active AIS transponders passed through the strait between Wednesday and Friday, a stark drop from the pre‑conflict average of 135 daily transits. Restoring the pipeline’s full capacity is expected to reinforce supply continuity for both domestic and international markets, providing a modest but meaningful cushion to the global economy as geopolitical tensions persist.

The United States and Iran left Islamabad without a peace deal, ending the most senior diplomatic encounter between the two nations since the 1979 Islamic Revolution. Vice President JD Vance, who led the U.S. delegation, told reporters that Tehran "refused to accept our terms" after a marathon 21‑hour session. Vance emphasized that the United States requires a "fundamental commitment" from Iran not to pursue nuclear weapons or the associated delivery systems. "We need an affirmative pledge that they will not seek a nuclear weapon, and they will not seek the tools that would enable them to quickly achieve a nuclear weapon," he said. Iran’s Ministry of Foreign Affairs, represented by spokesperson Esmaeil Baghaei, cautioned that no one expected a single‑session resolution. "Naturally, from the beginning, we should not have expected to reach an agreement in a single session," he told state broadcaster IRIB, adding that Tehran remains "confident that contacts with Pakistan and other regional friends will continue." Pakistan called on both parties to honor the ceasefire and pursue a durable peace. Foreign Minister Ishaq Dar expressed gratitude for the mediation efforts, stating, "We hope the two sides continue with a positive spirit to achieve durable peace and prosperity for the entire region and beyond." The stalled talks occur against the backdrop of a war that began on February 28, when the United States and Israel launched a campaign against Iran. The conflict has since spread across the Middle East, causing over 2,000 fatalities and extensive damage to both military and civilian infrastructure. One of the war’s most destabilizing effects has been a global energy crisis, as Iran tightened control over the Strait of Hormuz—a chokepoint through which roughly 20 % of the world’s oil and gas exports flow. The delegations, led by Vance for the United States and Iranian Parliament Speaker Mohammad Bagher Qalibaf, also discussed how to sustain a ceasefire that is already under strain from deep disagreements and Israel’s ongoing attacks on Hezbollah in Lebanon.

Hungarians are casting their votes in a parliamentary election that could mark a significant shift in the country's political landscape. Incumbent Prime Minister Viktor Orban, a eurosceptic nationalist, is facing his biggest electoral challenge after 16 years in power.The election for the 199-seat parliament began at 6am local time (0400 GMT) and is set to close at 7 pm (0500 GMT). Opinion polls over the last two weeks have shown Orban's Fidesz party trailing Peter Magyar's upstart centre-right opposition Tisza party by 7-9 percentage points, with Tisza at around 38-41 percent.Orban has framed the election as a choice between 'war and peace', warning that Tisza's victory could drag Hungary into Russia's war with Ukraine. However, many Hungarians have grown weary of Orban's 16-year rule, citing economic stagnation, soaring living costs, and reports of oligarchs close to the government accumulating wealth.A 24-year-old Budapest resident, Kriszta Tokes, expressed her concerns, stating, 'I am very excited but also very scared... I know that my future depends on this.' She added that she plans to leave Hungary if Orban wins.Despite the challenges, Orban remains optimistic, telling supporters in his birthplace Szekesfehervar, 'If we know ourselves well, if we know our country well and if we know our own people well, then I must say Hungarians will vote for safety on Sunday.'

Iran’s attempt to impose tolls on vessels passing through the Strait of Hormuz has been labeled illegal by Arsenio Domínguez, the head of the United Nations’ International Maritime Organization (IMO). In an interview with Al Jazeera, Domínguez stressed that such charges would set a dangerous precedent for global shipping. Tehran has asserted its right to levy fees even after the conflict ends, while U.S. President Donald Trump floated the idea of a joint U.S.-Iran venture to collect the payments. Both proposals clash with established maritime conventions. "Countries do not have the right to introduce tools or payments or charges on these straits," Domínguez said, adding that any toll system would be contrary to international law and could cripple the free flow of trade. The remarks came as marathon cease‑fire negotiations between U.S. and Iranian officials in Pakistan concluded without an agreement. U.S. Vice President JD Vance noted that Tehran rejected Washington’s terms, which included a commitment to forgo nuclear weapons development, prompting the American delegation to depart Islamabad after presenting its "final and best offer." Iran’s state‑run Press TV blamed the stalemate on what it called the United States' "excessive demands," citing the toll issue and the nuclear programme as major points of contention. Despite a two‑week cease‑fire announced earlier in the week, maritime traffic remains severely limited. Only 22 vessels with active AIS signals exited the strait between the truce’s start and Friday, a stark drop from the pre‑conflict average of about 135 daily transits, according to S&P Global. The bottleneck is throttling oil and natural‑gas exports from the Gulf. The U.S. military reported that two warships had navigated the waterway to clear Iranian mines, a move Iran denied. President Trump later insisted the strait would reopen "fairly soon," with or without Tehran’s cooperation. Domínguez emphasized that ending the hostilities is the fundamental solution to restoring safe passage. He warned that any resumption of traffic must be accompanied by thorough de‑mining and safety checks to protect both vessels and crews. He also dismissed calls for new legal frameworks, noting that the 1968 traffic‑separation agreement between Iran and Oman—which splits the strait into north‑ and south‑bound lanes—had functioned effectively before the war and does not require revision. Humanitarian concerns feature prominently in Domínguez’s statements. He highlighted that roughly 20,000 seafarers are stranded in the Gulf due to the blockade, warning that prolonged isolation would not only harm these workers but also have a negative ripple effect on the global economy.

U.S. Vice President JD Vance, heading the American delegation in the Islamabad talks, announced that the United States has yet to receive a concrete commitment from Tehran on its nuclear program and that Washington has put forward its best and final offer to Iran.Iranian media reports that the historic negotiations in Pakistan’s capital will resume for a second day. Observers note that the Strait of Hormuz remains a critical sticking point, underscoring the broader strategic stakes for regional security and global energy flows.

Britain’s cabinet is set to introduce a sweeping bill that would let ministers dynamically align UK regulations with EU single‑market rules using so‑called Henry VIII powers. The proposal would enable the government to adopt evolving EU standards in sectors such as food, drink, automotive and emissions trading without the need for a separate parliamentary vote on each change.The legislation is tied to the forthcoming food and drink trade deal with the EU, which the government claims will generate £5.1 billion a year for the British economy. By granting ministers the ability to implement new EU rules through secondary legislation, the bill aims to cut red tape, lower costs for businesses, and accelerate the rollout of trade agreements.Under the proposed framework, Parliament would retain the ability to approve or reject secondary legislation but would not be able to amend it. Critics warn this could turn MPs into mere "rubber‑stamps" for EU‑aligned regulations, limiting democratic scrutiny and potentially provoking retaliatory measures from the EU if the UK blocks such instruments.Political analysts note that the move comes amid heightened geopolitical tension following the United States’ war with Iran, which has exposed the fragility of Britain’s special relationship with Washington. Ministers argue that deeper regulatory alignment with the EU will add billions to the UK economy, mitigate the cost of the conflict, and address the “sluggish productivity” that has plagued the post‑Brexit era.Economic forecasts from the Office for Budget Responsibility (OBR) underscore the stakes: Brexit is projected to cut long‑run productivity by 4 % and shrink both exports and imports by 15 % compared with a scenario where the UK remained in the EU. Proponents of the bill contend that aligning with EU standards without re‑joining the customs union or single market will help reverse these losses while respecting political red lines on sovereignty and freedom of movement.Opposition parties, including hard‑Brexit advocates and the Liberal Democrats, have signalled they will challenge the bill, particularly in the House of Lords. The government acknowledges that while the Commons is unlikely to reject the proposal, the Lords could pose a significant obstacle.Academic voices, such as Prof Anand Menon of the think‑tank UK in a Changing Europe, caution that the approach amounts to “integration with the EU by stealth,” stripping the UK of a vote on the rules it will be forced to follow. He describes the situation as “the ugly trade‑off of Brexit,” where political control is sacrificed for economic access.Supporters counter that the bill will streamline the implementation of existing and future agreements, with any regulatory disputes to be settled by an independent tribunal rather than an EU court. They argue this balances the need for swift economic action with the preservation of constitutional safeguards.Prime Minister Keir Starmer has framed the initiative as part of a broader “reset” of UK‑EU relations, emphasizing a strategic partnership that deepens trade and defence cooperation while avoiding a return to the customs union or single market membership. The government stresses that Parliament will still play its “full constitutional role” in scrutinising the legislation.

GSK has revealed promising early results for its treatment for gynaecological cancers, Mocertatug Rezetecan (Mo-Rez), as its chief executive, Luke Miels, seeks to speed up drug development at the group.The company reported that in an early-stage trial, Mo-Rez shrank or eliminated tumours in 62% of patients with ovarian cancer where chemotherapy had failed, and in 67% of those with endometrial cancer.GSK acquired the Mo-Rez cancer treatment, an antibody-drug conjugate (ADC), from China’s Hansoh Pharma in late 2023, and has trialled it in 224 patients around the world, including the UK, over the past year. Few patients needed to stop treatment because of side-effects, the most common being nausea. It is administered every three weeks via intravenous infusion.Combined with data from a separate, intermediate trial in China, these results give GSK the confidence to go straight to late-stage trials, with five clinical studies planned globally in the next few months, including on patients in the UK.Presenting the results at the Society of Gynecologic Oncology’s annual meeting on women’s cancer in Puerto Rico, Hesham Abdullah, GSK’s global head of cancer research and development, said: “Treatment of gynaecological cancers remains a major challenge, with a pressing need for new therapies that offer improved response rates. With Mo-Rez we now have compelling evidence of a promising clinical profile.”Endometrial cancer affects 1.6 million women globally, with 417,000 new cases each year. Ovarian cancer affects 843,000 people, with 240,000 new cases annually.Abdullah described Mo-Rez as a “key asset” in the company’s growing cancer portfolio, expected to be a blockbuster drug with peak annual sales of more than £2bn, which GSK hopes will help it achieve its 2031 sales target of £40bn.