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Scotland has taken a significant step in the early detection and treatment of spinal muscular atrophy (SMA), a rare genetic condition that causes progressive muscle wastage, by becoming the first part of the UK to screen newborn babies for the condition.The screening, which is part of the existing heel prick test offered to all parents in Scotland about four days after birth, is funded by the Scottish government and pharmaceutical company Novartis. The goal is to assess how well screening can detect SMA earlier, allowing babies to receive treatment as soon as possible.SMA affects an estimated 1 in 14,000 births worldwide and impacts movement, breathing, and swallowing. Without treatment, it can limit life expectancy to two years. The condition was brought to wider attention after former Little Mix singer Jesy Nelson revealed in January that her twin daughters had been diagnosed with SMA.Campaigners, who have long advocated for newborn testing, hope the Scottish pilot will result in approval for the heel prick test across the UK. Giles Lomax, chief executive of SMA UK, said the screening pilot in Scotland would be “a huge impetus for other parts of the UK to speed up their own testing plans”. He hopes the Scotland trial will provide data that would convince the UK National Screening Committee to approve UK-wide testing.There is no cure for SMA, but there are now three NHS-funded drug treatments available. Lomax emphasized that with these treatments and newborn screening, “the future for anyone diagnosed with SMA is very different compared to their peers who were diagnosed symptomatically. It basically gives children the life they deserve.”

Moma Foods, a British porridge and oat drink brand, has issued a recall for several of its porridge products in the UK due to a potential mouse contamination at their manufacturing site. The recall affects seven versions of its pots and two of its sachets.Customers are advised not to consume the affected products and to return them to the place of purchase for a full refund. The Food Standards Agency (FSA) confirmed the recall on its website, stating that these products may contain mouse contamination, making them unsafe to eat.The affected products include:Porridge pots: almond butter and salted caramel; apple, cinnamon and brown sugar; banana and peanut butter protein; blueberry and vanilla; cranberry and raisin; golden syrup; and plain no-added sugar.Sachets: almond butter and salted caramel; and apple, cinnamon and brown sugar.Moma Foods emphasized that the chance of contamination is low, but they have taken this precautionary step to ensure consumer safety. The company was founded in 2006 in a railway arch in Deptford, south-east London, initially selling porridge and smoothies.

The recent decision by the Small Business Administration (SBA) to deny loans to small business owners who are not US citizens has raised concerns about the politicization of the agency. Kelly Loeffler, the new administrator of the SBA, announced that the agency would no longer approve loans to small business owners unless they are US citizens, effectively excluding legal immigrants with green cards and full residency from accessing loans.This move has been criticized for being a political decision that harms small businesses and the economy. The SBA's mission is to support small businesses, which are the backbone of the US economy. By denying loans to certain entrepreneurs, the agency is limiting access to capital and hindering the growth of small businesses that could benefit their communities and the country at large.The decision is also seen as a reaction against the Biden administration's efforts to promote diversity and inclusion. Under Biden, the SBA had often featured diverse groups of business owners in its marketing materials, but this new policy seems to be tailoring the message to serve the Trump administration's political agenda.Supporting small businesses should not be a controversial position, and most of the time it is not. However, the SBA's politicization has made it a propaganda tool for the party in power, rather than a neutral agency serving the interests of small businesses.To address this issue, some suggest taking the SBA out of the government and spinning it off into a separate entity, similar to the Manufacturing Extension Partnership or the MITRE Corporation. This entity would be funded by both the government and private industry and would be required to report to Congress through its existing small business committees.The goal of this new entity would be to coordinate government loan guarantees, assist with federal funding, and provide training, counseling, and support to small businesses. This would help to insulate the agency from political cycles and ensure that it serves the interests of small businesses, rather than the interests of the party in power.

When Resident Evil emerged in the mid-1990s, it stood in stark contrast to the prevailing gaming landscape. The PlayStation and Saturn consoles were dominated by bright, arcade-style games like Daytona and Tekken, while Japanese publisher Capcom was primarily known for Street Fighter and Mega Man sequels. Scary games were rare at the time and mostly confined to the PC, making Capcom's horror title Biohazard (the Japanese name for the series) a radical departure that caught the attention of games journalists.Three decades later, the series has not only survived but flourished, becoming one of gaming's most successful franchises. Resident Evil has sold more than 180 million copies worldwide, with 11 core titles, numerous spinoffs and remakes, plus extensive film, television, and anime tie-ins. Its characters and monsters have become cultural icons, with its design tropes now embedded in gaming practice.The origins of Resident Evil can be traced back to 1989's Sweet Home, a Capcom role-playing game for the Famicom (Japanese NES). The game featured a group of filmmakers searching a haunted mansion for valuable artifacts, and while it was a modest domestic success, it never received an international release. However, senior producer Tokuro Fujiwara couldn't let go of his vision for horror as a distinct game genre."We have Tokuro Fujiwara to thank for the existence of Resident Evil," says Alex Aniel, author of acclaimed Resident Evil history book Itchy, Tasty. "He directed Sweet Home having believed that horror could become its own game genre, but wasn't satisfied with its rudimentary portrayal. He wanted to give horror another try once the technology was there to allow it – that opportunity finally arrived with the release of the original PlayStation."In 1993, young producer Shinji Mikami was brought in to oversee a horror game project inspired by Sweet Home. He expanded the haunted mansion concept, drawing influence from George A Romero's Dead trilogy and Alone in the Dark, creating a world haunted not by ghouls but by zombies, mutants, and monsters. The heroes were an experienced SWAT team investigating disappearances at a rural mansion owned by the sinister scientific organization: Umbrella Corp.The original vision for full real-time 3D visuals proved too ambitious for PlayStation hardware, leading Mikami and programmer Yasuhiro Anpo to develop a compromise: 3D characters combined with prerendered 2D backgrounds viewed from fixed camera angles. This restricted, expressionistic style emphasized the intense claustrophobia of the environment, with information always kept from the player by blind corners and shadowy doorways.This combination of tension, omission, and restriction is fundamental to Resident Evil's success as a horror franchise. Even as the camera evolved to over-the-shoulder views and first-person perspectives, characters remained vulnerable. Ammo, save points, and health items are jealously rationed, with extremely restricted inventories. This approach makes Resident Evil operate more like classic horror literature than a typical power fantasy video game.The series has also expertly referenced horror conventions while paying homage to its inspirations. "Kamiya's biggest source of inspiration came from Alien and especially its sequel, Aliens," says Aniel of Hideki Kamiya, who directed Resident Evil 2 and Resident Evil Zero. "For example, in Resident Evil 2, humans infected with the G-virus grow a parasite that eventually ruptures their host and emerges from within, growing into deadly creatures."Resident Evil has also demonstrated remarkable versatility in exploring different horror genres – gothic horror in its mansions and monstrous enemies, sci-fi horror in its biological experiments, and folk horror in its sinister villages and religious cults. This comprehensive approach allows it to mirror societal fears, a point underscored by the COVID-19 pandemic."The Covid pandemic reminded us just how real our fear of viruses should be," says Bernard Perron, professor of cinema and video games at the University of Montreal. "In that sense, the fear of a corrupt corporation like Umbrella, along with mad scientists who do not necessarily have humanity's best interests at heart, continues to resonate. These anxieties remain deeply embedded in our posthumanist societies."Throughout its evolution, Resident Evil has maintained a balance between familiarity and innovation. Characters like Jill Valentine, Claire Redfield, and Leon Kennedy provide continuity – relatable but cool figures who spout wry jokes like Hollywood heroes. Meanwhile, charismatic antagonists such as Albert Wesker, Lord Osmund Saddler, and Lady Dimitrescu ensure consistent engagement.The series also excels in pacing and structure, carefully delineating between exploration, puzzle-solving, and combat sections. Locations are filled with beautiful details – lavish furniture, eerie oil paintings, ornate gardens – making exploration pleasurable. After intense battles, players can retreat to safe spaces like Save Rooms, creating a rhythm that prevents fatigue."The series offers deep and entertaining gameplay experiences, but with a very low barrier to entry, even for newcomers," says Aniel. "The Resident Evil games are more accessible than ever: since they are often on sale, they are affordable even for customers in emerging global markets, available on every major game platform."Ultimately, Resident Evil's longevity stems from its ability to create uncertainty while maintaining familiarity. "You know what you will get, but you also don't know," the article concludes. "Around every corner there could be a shock or there could be nothing – it's the uncertainty that gets you. It allows us to write in our own fears and anxieties, or to discover new ones we hadn't considered or acknowledged. Like all great horror fiction, Resident Evil has survived because it looks us right in the eye and says, I know what scares you. Come and see."

The recent pronouncement by a judge in Afghanistan, stating 'a few beatings won't kill you,' when rejecting a woman's divorce request from her abusive husband, highlights the dire situation for women under Taliban rule. This barbaric stance is not isolated but part of a broader global pushback against women's rights.The Heritage Foundation, architect of Project 2025, has published a report advocating for a deeply patriarchal model that encourages women to have more babies earlier in life and discourages further education and careers. This vision aligns with Donald Trump's second term agenda and has sparked concern among women's rights advocates.The proposed UN merger of UN Women and UNFPA has caused alarm among feminist groups. They warn that this consolidation will lead to reduced funding for gender equality programs and give countries like the US, which are hostile to women's rights, more influence over global structures supporting gender equality.UN Secretary General António Guterres noted that the world remains male-dominated, and there are well-funded efforts to maintain this status quo. The UN's next moves will be closely watched, as they have significant implications for women's rights globally.

The world is currently experiencing unprecedented levels of global instability and insecurity, with multiple conflicts erupting in regions such as the Middle East, Ukraine, Gaza, Sudan, and Lebanon. In response, the UK has increased its defence spending at the fastest pace since the end of the Cold War. This increase is being funded partly through a reduction in overseas aid spending over the next three years, a decision also made by several allied countries. Despite this, the Labour government emphasizes that its commitment to international development remains strong, viewing it as a fundamental part of its moral purpose and national interest. The reduction in aid does not signify a withdrawal from global responsibilities, but rather a strategic shift in prioritizing spending. The government plans to focus on areas with the greatest needs, particularly in fragile and conflict-affected countries such as Sudan, Palestine, Ukraine, and now Lebanon. Support for these regions is crucial for preventing humanitarian crises and promoting global stability. The new approach to development will prioritize: Innovative development strategies that deliver more impactful results Partnerships over paternalism, working closely with countries to build their own capacities Conflict prevention and resolution, particularly through education in conflict zones Climate and nature action to mitigate the effects of extreme weather Unlocking new sources of finance to drive growth and economic development The UK aims to lead reforms in international development, modernizing multilateral institutions and increasing investment in critical areas such as women's health and the BBC World Service. The government asserts that its values have not changed, and it remains committed to justice and global stability, even in the face of new security challenges.

CrossSense, an innovative AI software, has been awarded a £1m prize for its groundbreaking technology designed to assist individuals with dementia. This cutting-edge system is integrated into smart glasses and features a user-friendly assistant named Wispy. The smart glasses, equipped with a camera, microphone, and speakers, provide wearers with real-time guidance and support through everyday tasks.Wispy offers verbal cues and text prompts that float in front of the wearer's eyes, enhancing their ability to navigate daily life. The AI assistant can also engage in light conversation, ask questions, and aid reminiscences, significantly improving the wearer's independence and quality of life.The Longitude Prize on Dementia, funded by Alzheimer's Society and Innovate UK, aims to encourage the development of technology that helps people with dementia stay independent for longer. About 150 million people are expected to be living with dementia by 2050, making such innovations crucial.The CrossSense technology is expected to cost around £50 a month per subscription, with the smart glasses potentially costing up to £1,000. However, the developers plan to make the technology more affordable over time. The team behind CrossSense plans to conduct a pilot study with smart glasses in people's homes later this year.Prof Julia Simner, who led the study, noted that participants with dementia could correctly identify 46% of household items without the glasses, increasing to 82% with the glasses. An hour after removing the glasses, the identification rate remained high at 78%.While experts praise the innovation, they also highlight the need for larger, more controlled studies to test the device's effectiveness and address ethical considerations regarding data collection and user consent.

The WebKit Vulnerability and the New Patching MechanismApple has officially rolled out its first 'background security improvement' update, marking a significant evolution in its software maintenance strategy. This latest release targets a critical vulnerability discovered in WebKit, the browser engine that powers Safari across iPhones, iPads, and Macs.The advisory reveals that the bug, if exploited, could allow a malicious website to potentially access data from another website within the same browser session. To mitigate this risk, Apple introduced a new category of updates designed to be 'lightweight' and pushed between major software releases.Target Version: iOS, iPadOS, and macOS 26.1 and higher.Scope: Fixes for Safari, WebKit, and system libraries.Deployment: Background updates without requiring a full system reinstall.Efficiency in Security Response: The 'Quick Reboot' AdvantageOne of the most notable aspects of this update is the user experience. Unlike traditional major updates that often require lengthy reboots, this background security improvement only necessitates a quick device restart. This suggests a streamlined deployment process that minimizes user friction while maximizing security coverage.Apple has been testing this feature with software testers prior to the public release, indicating a deliberate effort to refine the mechanism before a wider rollout. The decision to withhold a specific reason for the patch from the public advisory highlights the sensitive nature of the vulnerability.Redefining the Security Patching LifecycleThe introduction of this update model fundamentally changes how Apple addresses the threat landscape. By decoupling critical security fixes from major feature updates, Apple can respond to zero-day threats and active exploits much faster.This approach reduces the 'window of exposure' for users, ensuring that security patches are applied as soon as they are available, rather than waiting for the next annual or bi-annual major OS release cycle.The Future of Continuous SecurityAs this is the inaugural release of the background security improvement program, it sets a precedent for future updates. We can expect to see a shift toward a more continuous security model, where minor but critical patches are pushed regularly to keep devices secure against evolving cyber threats.

In El Salvador, the Oriente Salvaje surf spot, known for its world-class breaks, Las Flores and Punta Mango, is facing significant threats from climate change. The local economy, heavily reliant on surf tourism, sputters to a halt due to intense tropical storms causing flooding and disrupting transport routes.To mitigate these risks, Rodrigo Barraza, a local surfer, teamed up with Save the Waves, an international surfing nonprofit organization. They took out a parametric insurance policy for Oriente Salvaje, which can be used to support recovery from climate change impacts. This policy is triggered when damaging conditions cross a predetermined threshold, such as wind speed or rainfall level.The project aims to provide rapid support for the local community, which includes hotels, restaurants, surf shops, fishers, and drone experts. A survey of 50 local businesses showed that, on average, 70% of their income was dependent on surf tourism. Several informal operators, such as surf photographers, guides, and boat drivers, are especially vulnerable to changeable weather.The payout will be triggered once weather conditions reach an extreme associated with observable income loss. It will be distributed to anywhere between a few hundred and several thousand beneficiaries in the region. The size of the payout is still being determined, as well as which insurer it will be, but Save the Waves hopes to have a pilot running by June.The pioneering program has not been hurdle-free. Angelo Picardo, Save the Waves' local coordinator, says: "El Salvador is a developing country and we don't have an insurance culture – people don't even have health insurance – so there's a lot of work you have to do on the ground to bring people on board."Another challenge has been funding the premiums without burdening local businesses. Save the Waves is in talks with the Salvadorian government, which since 2019 has been channelling millions from loans into a nationwide surf tourism initiative.This type of insurance is bound to spread as more communities and ecosystems experience weather extremes. However, Swenja Surminski, an international expert on innovative insurance for ecosystems, warns that "parametric solutions must be combined with broader resilience and adaptation strategies".