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The crew of Artemis II is preparing to return to Earth on Friday, following their historic 10-day lunar flyby mission. Nasa leaders have outlined the critical steps needed to ensure a safe splashdown off the coast of San Diego. The Orion capsule will travel at nearly 24,000mph before making a final splashdown several miles off the coast of San Diego. The operation requires multiple teams and careful coordination to safely extract the crew from the spacecraft. Nasa's associate administrator Amit Kshatriya emphasized the importance of the mission, stating, "To every engineer, every technician that's touched this machine, tomorrow belongs to you. The crew has done their part. Now we have to do ours." Jeff Radigan, lead flight director of the mission, highlighted the precision required for re-entry, noting the team has "less than a degree of an angle" to hit the correct flight path. "Let's not beat around the bush. We have to hit that angle correctly – otherwise we're not going to have a successful re-entry," he said. The splashdown is expected to occur at 5:07pm PT, with the USS John P Murtha ready to assist with recovery operations. The crew will undergo post-mission medical evaluations before being flown to Nasa's Johnson Space Center in Houston, Texas. Pilot Victor Glover, the first Black man to travel beyond low Earth orbit, reflected on the journey, saying, "We have to get back. There's so much data that you've seen already, but all the good stuff is coming back with us. There are so many more pictures, so many more stories."

Max Verstappen's future in Formula One has been thrown into doubt after his long-time engineer, Gianpiero Lambiase, announced that he will be leaving Red Bull to join McLaren in 2028. Lambiase has been a crucial part of Verstappen's team since 2016, playing a key role in his four world championships.The news is a significant blow to Red Bull, as Lambiase's departure comes at a time when Verstappen has been expressing disenchantment with the current F1 regulations. The Dutch driver has been vocal about his frustration with the focus on energy management, which he believes has made the racing less enjoyable.Verstappen's contract with Red Bull runs until 2028, but performance-related escape clauses could allow him to exit before then. The team has been going through a period of change, with several key figures leaving, including Christian Horner as team principal, Adrian Newey as chief designer, and Jonathan Wheatley as sporting director.Lambiase's move to McLaren will see him take on a role supporting the team principal, Andrea Stella. The British-Italian engineer has been a close ally of Verstappen, and their partnership has been highly successful. Their radio interactions during races have been closely followed, showcasing a strong professional and personal bond.The departure of Lambiase and other key figures has raised questions about the future of Red Bull and Verstappen's commitment to the team. With the current regulations and the competitiveness of the Red Bull car, Verstappen's future in F1 is uncertain.

Tyson Fury is set to make a highly anticipated return to the boxing ring on Saturday night, facing off against Arslanbek Makhmudov at Tottenham Hotspur Stadium in London. The Gypsy King, known for his bold claims and unorthodox style, has promised a destructive knockout to mark his comeback. “It’s going to be different because, for the first time in forever, I’m the hunter,” Fury declared at the fight’s final press conference. “I’m not the hunted, and we all know that when I’ve always been the hunter in the past, I’ve always fucked people up.” Fury, who announced his retirement from boxing in January 2025 but quickly reversed his decision, expressed his excitement about returning to the sport. He cited his long-term rival Anthony Joshua’s car crash in Nigeria as a defining moment that made him realize the importance of living in the present. Makhmudov, a formidable Russian opponent standing at 6 feet 7 inches and weighing 18 or 19 stone, seemed unfazed by Fury’s bold claims. “I’m happy and very excited to be here. I can’t wait for Saturday night,” he said. The Russian fighter from Dagestan added, “I don’t have pressure, because God prepared me for this moment all my life. I believe this is my time.” Fury, known for his bombastic delivery, also expressed sympathy for his opponent, stating, “I actually feel sorry for Makhmudov because I’m going to make an example of him. He’s a big lump, but I’ll knock his head right off his shoulders.”

UK Prime Minister Keir Starmer has expressed his concern over Israel's ongoing attacks on Lebanon, emphasizing that they 'shouldn't be happening' and must stop immediately. During his visit to the Middle East, Starmer called for the Iran conflict to be a turning point for the UK's future security. In an article for the Guardian, Starmer outlined the need for a fundamental reset in the UK's approach to make the country more resilient, including boosting defense and strengthening ties with Europe. He highlighted the importance of not being drawn into offensive military action, while rebuilding European alliances and increasing defense capacity. Starmer's comments echo those of Yvette Cooper, the foreign secretary, and John Healey, the defense secretary, indicating a potential divergence between the UK and the US under Donald Trump over the Iran conflict. The UK has been adamant that the Strait of Hormuz must remain free of tolls or levies, contrary to Trump's suggestion of a 'joint venture' between the US and Iran. Starmer criticized Israel's intensified bombing in Lebanon, which has resulted in over 250 deaths. He emphasized that the issue is 'a matter of principles' and not a technical one, dismissing arguments that the attacks are not part of the ceasefire agreement. The UK's stance has been to support the ceasefire and advocate for the inclusion of Lebanon in the agreement. Starmer also emphasized the need for the UK to be closer to the EU on defense, security, trade, and energy to strengthen the economy and make it more resilient. He highlighted that the war in Iran must be a 'line in the sand' and that the UK's response will define its future for a generation.

The latest Cannes lineup reveals a clear pivot from the usual Hollywood glamour toward a roster dominated by celebrated world‑cinema auteurs such as Pedro Almodóvar, Cristian Mungiu and Asghar Farhadi. While last year’s festival was anchored by a Mission: Impossible spectacle starring Tom Cruise, this edition offers a more eclectic mix, including debut features from Andy Garcia (who also stars in his crime drama Diamond) and John Travolta, who directs the aviation‑themed Propeller One‑Way Night Coach based on his own novel.Under the stewardship of director Thierry Frémaux, Cannes continues to bar films that are exclusive to streaming platforms, a stance that has been vindicated by recent Oscar successes for festival selections. The festival also entered the AI debate: Steven Soderbergh’s documentary John Lennon: The Last Interview employs artificial intelligence to reconstruct visual elements of the legendary interview, sparking both fascination and unease among attendees.Gender representation remains skewed, with a noticeable predominance of male directors in the competition slate, although the final list is still pending. Notably absent are any British filmmakers, despite the inclusion of Polish auteur Paweł Pawlikowski, whose biopic of Thomas Mann, Fatherland, could be loosely claimed as a UK entry given his long residence there.Geopolitical undercurrents are hard to ignore. Russian director Andrey Zvyagintsev returns with Minotaur, a film about a beleaguered Russian businessman. Zvyagintsev, once favored by Vladimir Putin, now lives in exile in France, adding a layer of political intrigue to his work amid the ongoing war in Ukraine.The competition also features a strong historical thread: László Nemes’s Moulin revisits occupied France, Emmanuel Marre’s Notre Salut explores Vichy‑era France, and Lukas Dhont’s Coward follows a Belgian soldier’s harrowing experience in World‑I trenches.Among the more provocative entries, Nicolas Winding Refn’s Her Private Hell promises shock value in the out‑of‑competition slot, while the Un Certain Regard section showcases Jane Schoenbrun’s queer slasher Teenage Sex and Death at Camp Miasma, likely to become a festival highlight.

A 47‑year‑old woman who had endured three life‑threatening autoimmune diseases for more than a decade is now living a near‑normal life after an experimental CAR‑T cell therapy reset her immune system at University Hospital Erlangen in Germany.Before the procedure she had exhausted nine different treatments with no lasting benefit, relying on daily blood transfusions and continuous anticoagulation to manage her illnesses.Within weeks of the infusion, doctors observed rapid improvement in all three conditions—a world‑first outcome. She has remained in treatment‑free remission for 14 months and has largely returned to everyday activities.Prof Fabian Müller, who led the team, called the speed and depth of the response “remarkable” and said the therapy “significantly improved her quality of life.” He emphasized that clinical trials are required to determine how durable the effect is and whether it can help other autoimmune patients.The patient suffered from three distinct disorders: autoimmune haemolytic anaemia (AIHA), where rogue immune cells destroy red blood cells; immune thrombocytopenia (ITP), which depletes platelets and raises bleeding risk; and antiphospholipid syndrome (APS), which promotes dangerous blood clots. All three stem from malfunctioning B‑cells.With no conventional options left, doctors turned to CAR‑T therapy, a technique that has revolutionised treatment for certain cancers. They harvested her white‑blood cells, isolated the T‑cells, engineered them to recognise the CD19 protein on B‑cells, and reinfused the modified cells.The engineered T‑cells swiftly eliminated the pathogenic B‑cells. She received her last blood transfusion a week after treatment and was able to perform routine tasks within two weeks. Follow‑up tests showed a reconstituted, healthy B‑cell population, suggesting an immune reset. The findings were published in the journal Med.She still exhibits a mildly low white‑cell count and slightly elevated liver enzymes, which researchers attribute to the cumulative impact of prior therapies rather than the CAR‑T product.Rheumatology expert Prof Ben Parker of Manchester University NHS Foundation Trust described the case as encouraging, noting that “the prolonged response off normal therapy suggests there has been an immune reset.” However, he warned that case reports alone cannot confirm efficacy and highlighted ongoing trials for lupus, myositis, multiple sclerosis, systemic sclerosis, vasculitis, and other autoimmune conditions.

British Airways announced that, when it resumes operations in July, its Middle East timetable will be significantly scaled back, with a portion of the freed‑up fleet redirected to launch additional direct services to India and Kenya. The carrier has suspended all flights to the region following the outbreak of the Iran‑related war. It plans to restart flights to Riyadh in mid‑May and to reopen routes to Dubai, Doha and Tel Aviv on 1 July. However, the airline will reduce Dubai flights from three to one per day and cut the frequency to Doha, Tel Aviv and Riyadh from two daily services to a single flight each. In a permanent move, BA will drop Jeddah as a destination from 24 April. Service to Bahrain and Amman will remain on hold until 25 October, while flights to Larnaca, Cyprus are slated to return on 22 May. Speaking on the adjustments, BA said, “Given the ongoing situation in the Middle East, we have revised our schedule to give customers clearer options. We continue to monitor the situation closely and are in direct contact with affected passengers to provide alternatives.” Since the conflict began, the airline has facilitated the repatriation of thousands of travelers, operated humanitarian relief flights, and increased capacity on key long‑haul sectors. Looking ahead, BA will deploy larger aircraft on its Delhi route from 1 June and similarly upscale the Hyderabad service. The summer schedule will also see additional daily flights to Bengaluru and Nairobi through late October. Further expansion includes new flights to Delhi and Mumbai, a development first reported by the Financial Times, underscoring BA’s strategy to offset reduced Middle East capacity with growth in high‑demand Asian and African markets.

Zack Polanski, the leader of the Green Party, has made a strong call to action for the UK government to withdraw its trade agreement with Israel in light of the recent Israeli strikes on Lebanon. Polanski expressed his concerns about Israel's actions, accusing them of 'behaving in a completely uncontrolled way.'During the launch of the Green party's local election campaign in London, Polanski urged the government to take a firmer stance against Israel, stating that it is 'outrageous that Israel is still enjoying diplomatic and trade privileges from the international community.' He emphasized the need for robust sanctions against Israel and an end to the 'genocide.'Polanski also criticized the UK government's claim of not being involved in the conflict with Iran, arguing that its bases had been used to aid US bombers attacking Iran. He called for the disentanglement of UK and US military operations and a ban on the US using UK airspace.When asked about the economic implications of ending the trade deal with Israel, Polanski prioritized human lives over financial concerns, stating that the UK should not put 'a cost on people's lives.'In addition to his comments on Israel, Polanski criticized Labour's housing policies, arguing that Green-run councils would focus on building new council houses and 'stand up' to property developers who resist building affordable homes. He accused Labour councils of building 'luxury, unaffordable buildings that no one's ever going to live in.'Labour responded by accusing Green party councillors of trying to block 42,000 homes across the country since 2018 and said they were not delivering social rented housing in areas where they were in power.

Europe is undergoing a significant transformation in its relationship with the US, marked by a growing desire for independence and a shift away from Trump's aggressive policies. The recent crisis in the Middle East, where Trump's threat to annihilate Iranian civilisation was temporarily called off, has been a turning point in this journey. Initially, many European leaders had tacitly supported the US and Israeli attack on Iran, driven by a desire for a transatlantic detente and antipathy towards the Iranian regime. However, as the war escalated, Europe's stance began to shift, with countries like Italy, Poland, and France taking steps to distance themselves from Trump's policies. The cooling of European support for the war has taken various forms, including Italy denying US warplanes permission to use an airbase in Sicily, Poland refusing to send Patriot air defence systems to the Middle East, and France rejecting overflight rights and opposing a US-sponsored resolution at the UN security council. This shift in European policy is driven by a number of factors, including the realisation that the war has been a windfall for Russia, through higher oil prices and a depletion of air defence interceptors available to Ukraine. European leaders have also been reminded that the erosion of international law is bad news for the world, Europe included. As Europe finds its footing in distancing itself from Trump, it may also find its voice. Europe's diplomatic role in the Iranian nuclear file in the early 2000s grew out of its opposition to the Iraq war. Today, the same dynamic could unfold, with Europe promoting a permanent end of hostilities and a multilateral initiative in the region. The proposal by a group of European, Gulf, and Asian countries to contribute to ensuring safe passage through the strait of Hormuz was originally aimed at placating Trump. Europeans then backed a UN-led fertiliser corridor to prevent a food crisis in the global south. The UK is also leading a coalition of more than 40 countries seeking to reopen the strait once the US and Israel definitively end their offensive. If a sustainable reopening of Hormuz succeeds, it could eventually extend to a new nuclear agreement, a non-aggression pact between the US and Iran, and a similar one between Israel and Iran – including Lebanon. It could involve the release of Iranian funds frozen abroad to rebuild infrastructure destroyed by US and Israeli attacks, and the selective lifting of EU and US sanctions.