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Mauricio Pochettino has distanced himself from speculation linking him to a return to Tottenham Hotspur, stating his full focus is on leading the US men's national team at the upcoming World Cup. Despite being linked to the Spurs managerial role, Pochettino emphasized his commitment to his current position.Pochettino, who led Spurs to significant successes during his tenure from 2014-2019, expressed confidence that his former club will avoid relegation, despite their challenging season. He cited the team's talented players and passionate fans as key factors in their likely survival.With Tottenham hovering just above the relegation zone and seven matches remaining, Pochettino's comments offer a boost to the club's morale. The team is reportedly close to appointing Roberto De Zerbi as their new manager, with a long-term contract on the table.Pochettino also left open the possibility of extending his stay with the US men's national team, stating that discussions about his future will take place after the World Cup. For now, his priority remains the team's upcoming friendly against Portugal.

Tottenham Hotspur is on the verge of appointing Roberto De Zerbi as their new manager following productive talks on Monday. The Italian coach has emerged as the club's top choice to replace Igor Tudor, who left his interim position on Sunday after failing to improve the team's form.De Zerbi, who recently parted ways with Marseille, is now the only viable candidate for the role, with Spurs not engaging with other potential candidates. The club aims to secure his services on a long-term contract, believing he can help them stay in the Premier League and build for the next season.The potential appointment of De Zerbi could also impact Mauricio Pochettino's chances of returning to the club. Pochettino, currently managing the US national team, had been considered for an emotional return to Spurs in the summer, but De Zerbi's possible arrival might rule out that move.De Zerbi's backing of Mason Greenwood during his time at Marseille has raised concerns among some Tottenham supporter groups. Greenwood was charged with attempted rape and assault in 2022, although the case was later discontinued. Despite these concerns, Spurs seem willing to overlook them to secure De Zerbi's appointment.The situation at Tottenham is critical, with the team currently one point and one place above the relegation zone and having gone 13 league matches without a win – their worst run since the 1934-35 season. De Zerbi's task would be to turn the team's fortunes around and secure their Premier League status.

Liverpool is optimistic that Mohamed Salah will return from injury in the FA Cup quarter-final against Manchester City on Saturday. The Egypt international has been sidelined with a muscle problem sustained during the Champions League match against Galatasaray.Salah, who announced his departure from Liverpool at the end of the season, was also forced to miss Egypt's friendlies against Saudi Arabia and Spain. However, he has responded well to treatment, and there is confidence he will be involved at the Etihad Stadium on Saturday.This potential return comes as Liverpool prepares for a crucial sequence of fixtures that could define their season. Arne Slot's side will be looking to make a strong impression, especially with the Champions League quarter-final first leg against Paris Saint-Germain approaching.In other injury news, Alexander Isak may also be available for the first time since fracturing a leg at Tottenham in December, although his comeback is expected to be more realistic for the Champions League match. The £125m British-record signing is expected to resume team training this week.On the other hand, Alisson, Liverpool's first-choice goalkeeper, is still nursing a hamstring injury and remains a major doubt for the trip to Parc des Princes. The 33-year-old has experienced repeated hamstring injuries in recent seasons.Meanwhile, Florian Wirtz has claimed that he has become a stronger player as a result of the problems he encountered after moving to Liverpool. The Germany international joined for a then club-record £116m from Bayer Leverkusen last summer but has struggled to impose himself in the Premier League.

Eli Lilly, the US pharmaceutical group behind the Mounjaro weight-loss drug, is seeking to resume its investments in the UK after pausing them last year. The company is in talks with UK ministers to regularly increase NHS drug prices and end a rebate scheme. Patrik Jonsson, president of Eli Lilly's international business, expressed optimism about reaching an agreement this summer.The talks will also explore 'innovative' pricing plans, such as linking payments for anti-obesity drugs to whether the treatment helps patients return to work. This comes as the US pharmaceutical industry increases pressure on the UK, with Keir Starmer agreeing to the first increase in NHS cost-effectiveness thresholds in 27 years. The threshold was raised from £20,000 to £30,000 a year for every year of life gained to £25,000 to £35,000.Eli Lilly was one of several pharmaceutical companies that ditched or paused almost £25bn in planned investments in the UK last year. The company paused its plans to invest in a laboratory site in central London. Jonsson stated that the resumption of Eli Lilly's investment would depend on the outcome of its talks with the government.He emphasized that prices for medicines in the UK had been 'far too low for far too long' and that the threshold couldn't remain static for another three decades. The UK agreed to pay 25% more for new medicines by 2035 as part of a US-UK drug pricing deal, which could eventually reach £9bn a year.Large pharmaceutical companies have protested about a 'rebate' scheme, under which they are required to pay back a chunk of revenue from sales of branded medicines. This scheme is expected to fall in 2026, although Jonsson believes payments 'should actually get down to zero' over time.

NASA is planning to send four astronauts on a 10-day loop around the moon on the Artemis II mission, marking a significant step towards returning humans to the lunar surface. The mission comes nearly 57 years after the last human visit to the moon during the Apollo 17 mission in 1972.The Apollo 11 moon landing, which took place on July 21, 1969, captivated the world as Neil Armstrong and Buzz Aldrin became the first humans to set foot on the moon's surface. Armstrong's iconic words, "That's one small step for man, one giant leap for mankind," echoed globally, symbolizing a historic achievement in space exploration.However, the current Artemis missions lack the same level of political and rhetorical urgency that drove the Apollo program. NASA has shifted its focus between the moon and Mars over the years, with Donald Trump justifying the mission in terms of "lunar economic development" and preparing for a future visit to Mars.Despite the challenges in replicating the excitement of the first moon landing, the moon remains a source of fascination throughout history, inspiring artistic expression and captivating the imagination of people worldwide. The Artemis missions, including the Artemis II crew, which includes Victor Glover, the first black astronaut, and Christina Koch, the first female astronaut, to reach the moon, may still spark public enthusiasm.As the world waits for the Artemis II mission to launch, it's clear that while it may not have the same world-historical importance as Armstrong's "giant leap," it still represents a significant step forward in space exploration and could potentially ignite a new wave of interest in lunar exploration.

UK savers who want to maximize their cash Isa allowance are being warned not to leave it until the last minute, as the deadline for applications is on Easter Sunday, April 5. The cash Isa allows individuals to save or invest up to £20,000 per tax year, with returns free of tax. Experts are advising savers to take action now, as the allowance for those under 65 will be reduced to £12,000 from the next tax year. This change, announced in last year's budget, aims to encourage younger savers to consider investing in the stock market. In April 2025, a record £14 billion was paid into cash Isas, and this year is expected to see a similar surge. Anna Bowes, personal savings expert at The Private Office, emphasized that savers need to act quickly, as some providers may withdraw their offerings early to process applications before the deadline. Savers can currently find competitive interest rates, with fixed rates of around 4.45% available from providers like Close Brothers Savings, Furness building society, and Vida Savings. For variable-rate Isas, Plum is offering 4.66%, and Tembo Money is paying 4.55%, both including a bonus for the first 12 months. Rachel Springall, finance expert at Moneyfactscompare.co.uk, warned that savers should not delay, as missing the deadline could mean losing the chance to use this year's allowance. She also recommended exploring options beyond traditional high street banks, as challenger banks and building societies are offering some of the best deals.

The concept of luck has long been shrouded in mystery, often attributed to chance or fate. However, behavioural neuroscience has made significant strides in uncovering the underlying mechanisms that govern luck. According to research, luck is not just a roll of the dice, but rather a complex interplay of brain chemistry and behaviour that can be influenced and cultivated.The neuroscience behind luck reveals that it operates through identifiable patterns of brain chemistry and behaviour. Studies have shown that the consistently lucky are not blessed by fate, but rather, they possess a unique set of habits and characteristics that enable them to capitalize on opportunities and navigate challenges more effectively. Brain imaging techniques have even identified specific regions of the brain that are activated when individuals perceive themselves as lucky, shifting their perception from threat-detection mode to opportunity-recognition mode.Serotonin production, regulated by morning sunlight, tryptophan-rich foods, and a regular sleep-wake cycle, plays a critical role in determining one's luck. Individuals who prioritize these factors are more likely to experience a boost in serotonin levels, which in turn, enhances their mood, social confidence, and resilience. Conversely, those who lead erratic lifestyles and neglect these factors may find themselves chronically sleep-deprived and less likely to encounter fortunate events.Lucky individuals also tend to possess a clear awareness of their interests and passions, which guides their decision-making and behaviour. By following their 'fascination compass', they are more likely to stumble upon opportunities and experiences that align with their values and goals. Novelty-seeking and a willingness to take calculated risks also characterize lucky individuals, as they understand that each small departure from routine can be a ticket to new experiences and encounters.Generosity and a willingness to help others without expectation of return are also key characteristics of lucky individuals. Brain imaging studies have shown that acts of genuine generosity activate the brain's deepest reward centre, releasing feel-good chemicals that reinforce positive behaviours and build social capital. By investing in others and cultivating meaningful relationships, lucky individuals create a network of opportunities and support that can help them navigate life's challenges.In conclusion, luck is not just a matter of chance, but rather a complex interplay of brain chemistry, behaviour, and habit. By understanding the underlying mechanisms that govern luck and incorporating these insights into daily life, individuals can increase their chances of experiencing fortunate events and leading a more fulfilling life.

Ukrainian President Volodymyr Zelenskyy has concluded defence agreements with the United Arab Emirates (UAE) and Qatar, focusing on joint expertise in countering threats from missiles and drones. The agreements were made during Zelenskyy's visit to Doha and the UAE earlier in the day. The defence pact with Qatar includes collaboration in technological fields, development of joint investments, and the exchange of expertise in countering missiles and unmanned aerial systems. This move comes as Iran continues to attack its Gulf neighbours, with Tehran insisting it targets only US assets in retaliation for the US-Israeli war on Iran. Ukraine has deployed 201 anti-drone experts to the Middle East to help Gulf nations counter Iranian drones. Kyiv has proposed swapping its interceptors for the more expensive air-defence missiles used by Gulf countries to down Iranian drones. Ukraine needs these missiles to fend off near-daily Russian missile attacks. The agreements highlight Ukraine's growing role as a leading producer of sophisticated, battlefield-proven drone interceptors. The country's expertise in downing Russian drones, which have been attacking Kyiv since the start of the full-scale invasion in 2022, is seen as a cost-effective solution for Gulf nations. For instance, Ukraine's interceptors cost around $2,000 each, compared to the $4 million cost of a Patriot missile. Zelenskyy's diplomatic tour aims to secure funding and technology in return for Middle East support. The US-Israeli war on Iran has depleted Patriot missile stocks, which concerns Ukraine as it needs these missiles to counter Russian ballistic missiles.

The United Nations Refugee Agency (UNHCR) has issued a grave warning that Lebanon faces the threat of a humanitarian catastrophe as Israel continues its weeks-long bombardment and expands ground operations across the country.UNHCR's Lebanon representative Karolina Lindholm Billing reported that Israeli strikes and forced displacement orders have affected people throughout Lebanon, from the southern regions to the Bekaa Valley, Beirut, and northern areas. More than 1.2 million people have been forced from their homes since Israel's intensified attacks began in early March, according to UN figures."The situation remains extremely worrying and the risk of a humanitarian catastrophe ... is real," Lindholm Billing stated during a briefing in Geneva. She emphasized that Lebanon's overstretched shelter system is struggling to meet the growing needs of displaced families.The UN representative highlighted particularly concerning developments, including strikes on central Beirut's densely populated neighborhoods where many had sought refuge in collective shelters. "The families are ... living in constant fear, and the psychological toll, particularly on children, will last far beyond this current escalation," she added.Israel launched its intensified attacks against Lebanon after Hezbollah fired rockets toward Israeli territory following the February 28 assassination of Iranian Supreme Leader Ayatollah Ali Khamenei in the US-Israel war on Iran. The Israeli military has since conducted aerial and ground operations across Lebanon while issuing mass forced displacement orders for residents of southern areas and several Beirut suburbs.On Friday, the Israeli military announced air strikes on Beirut and issued new displacement orders for neighborhoods including Haret Hreik and Burj al-Barajneh. Meanwhile, Hezbollah has continued rocket attacks into northern Israel and confrontations with Israeli troops in southern Lebanon.Rights groups have strongly condemned Israel's expanded operations, with Human Rights Watch warning that preventing Lebanese civilians from returning to their homes in the south may constitute the war crime of forced displacement. "Israel's tactics of mass expulsion in Lebanon raise serious risks of forced displacement," the organization stated. "Forced displacement and collective punishment are war crimes."International concerns have been further heightened by the Israeli military's destruction of civilian homes and several bridges connecting southern Lebanon to the rest of the country. "The destruction of key bridges in the south has cut off entire districts ... isolating over 150,000 people and severely limiting humanitarian access," Lindholm Billing explained.As the crisis deepens, Lebanon's government faces mounting challenges in responding to the rapidly deteriorating humanitarian situation, with evacuation orders now extending to areas previously considered safe, exacerbating panic among the civilian population.