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The Guardian’s latest science podcast examines the worldwide campaign to wipe out Guinea worm disease, a parasitic infection that could become the second human disease ever eradicated after smallpox. Hosted in 2026, the episode highlights why the disease remains a focal point for public‑health leaders and what its elimination would mean for global health security.Guinea worm, transmitted through contaminated water, has been the target of an intensive eradication effort led by the World Health Organization and partners in endemic regions. The podcast underscores the progress made: cases have plummeted from millions in the 1980s to just a handful today, illustrating the power of coordinated surveillance, safe‑water interventions, and community education.Despite the gains, experts caution that complete eradication is not guaranteed. Residual hotspots in remote villages, logistical challenges in delivering clean water, and the need for sustained funding pose ongoing risks. The discussion stresses that a lapse in commitment could allow the parasite to rebound, undoing decades of progress.Historically, smallpox remains the only disease humanity has fully eradicated, a milestone achieved in 1980 after a global vaccination campaign. The potential success of the Guinea worm program would mark a watershed moment, demonstrating that eradication is feasible beyond vaccine‑preventable illnesses and could inspire similar initiatives for other neglected tropical diseases.Listeners are encouraged to support the effort through the Guardian’s science podcast platform, where additional resources and ways to contribute are provided. As the episode concludes, the hosts reiterate that the fight against Guinea worm is both a test of global solidarity and a template for future disease‑elimination campaigns.

What has happened?The war in the Middle East has choked the Strait of Hormuz, cutting oil‑shipping routes. Crude prices surged to $119 a barrel in March from $72 pre‑war – a rise of $47 or roughly 65%. ACI Europe warns that unless stable supply returns within three weeks, jet‑fuel shortages will force cancellations, potentially from May. Susannah Streeter of Wealth Club notes a growing risk for leisure flights. If your flight is cancelledFor flights departing from or arriving at UK/EU airports on UK/EU carriers, passengers must receive a refund or an alternative flight. Cancellations less than two weeks before departure also trigger compensation under EU Regulation 261/2004 – up to €600 depending on distance. Airlines must provide meals, transport and accommodation while stranded. Refund or re‑routing – mandatory for covered flights.Compensation – up to €600 if notice is under two weeks.Support services – meals, hotel, transport. Package holiday travellersPackage holidays fall under the Package and Linked Travel Arrangements. The tour operator must either offer an alternative holiday of equal value or a full refund if the flight leg is cancelled. Rory Boland of Which? Travel stresses that the provider also arranges return transport. Surcharges for fuel price rises can be up to 8%; any higher charge gives the consumer a right to cancel with a full refund. Self‑arranged tripsTravelers who book flights and accommodation separately have weaker protection. While airlines must refund or re‑book the flight, hotels and other services are not automatically covered. Matt Gatenby of Travlaw advises checking travel‑insurance policies, which may cover hotel losses, though terms vary. Credit‑card protectionsPurchases over £100 made with a credit card are covered by Section 75 of the Consumer Credit Act, making the card issuer jointly liable if the airline fails to deliver. This recourse is secondary to airline refunds and does not extend to separate hotel bookings. Pre‑booking adviceExperts recommend a “belt‑and‑braces” approach: book a package holiday with a credit card, secure comprehensive travel insurance, and choose accommodation with flexible cancellation. Be aware of potential delays at European borders – the EU’s new Entry‑Exit System (EES) can cause up to three‑hour queues, jeopardising flight connections. Airline and hub considerationsLarge carriers are more likely to have fuel‑hedging contracts, insulating them from immediate price spikes. Hub airports such as Heathrow and Barcelona typically have multiple fuel supply routes (pipelines and trucks), offering greater resilience and more alternative flights in case of cancellations. Booking timingHistorically, fares rise as departure approaches, and the cheapest seats are found early in the sales cycle. However, limited summer inventory means some airlines may later discount if demand softens due to fuel‑price anxiety.

Rivalry and Managerial Banter David Moyes teased Arne Slot before the Merseyside derby, joking about refereeing bias at Anfield while acknowledging Slot’s coaching credentials. The Everton supporters’ group 1878s unveiled a tifo titled “The Originals”, featuring Hill Dickinson, Goodison Park, Anfield, the 1891 league‑championship Liver Bird and a Beatles‑inspired scarf, sparking a social‑media spat. League Context and Points Gap Current gap: 2 points separates Everton and Liverpool in the Premier League table. Last season the gap was 11 teams and 36 points. Everton sit around 12th‑14th place, with a realistic chance to finish 12th if results go their way. Financial Disparity and European Ambitions Last season turnover: Liverpool £703 million vs Everton £196.7 million – a difference of £506.3 million, roughly 2.6× Liverpool’s revenue. Only five points now separate the clubs, making a European qualification for Everton a plausible outcome with six games left. Qualifying for Europe would boost Everton’s global profile and attract higher‑calibre players, according to Moyes. Everton’s Transformation Under Moyes Since returning 15 months ago, Moyes has lifted Everton from relegation battles to a mid‑table push, highlighted by an “emphatic defeat of Chelsea” at Goodison. He cites the new stadium and improved finances under the Friedkin Group as key enablers, while acknowledging recruitment challenges – only a handful of players accepted moves last summer.

Lionel Messi delivered a brace to propel Inter Miami to a 3-2 victory over the Colorado Rapids on Saturday in Denver, securing three points in Major League Soccer and keeping the club in contention for a strong playoff push.The match, held at Empower Field before a crowd of 75,824 spectators—the second‑largest attendance in MLS history—saw Miami take an early lead when a pass from goalkeeper Zack Steffen was intercepted by Yannick Bright, allowing Messi to convert a 13th‑minute penalty and put the visitors ahead 1-0.Inter Miami extended the advantage to 2-0 during first‑half stoppage time after a swift passing sequence culminated in a header by German Berterame, set up by Rodrigo De Paul’s cross. Colorado responded with goals from Rafael Navarro (58') and substitute Darren Yapi (62'), leveling the score at 2-2.Messi reclaimed the lead in the 79th minute, launching a solo run from midfield and striking the ball into the upper left corner for a go‑ahead goal. The Argentine’s decisive strike proved crucial as Miami held on despite being reduced to ten men when Yannick Bright received a red card in the 87th minute.With the win, Inter Miami improved to 4‑1‑3 (15 points) while Colorado slipped to 4‑4‑0 (12 points), underscoring Miami’s upward trajectory in the Eastern Conference standings.Beyond the result, the match highlighted the growing popularity of MLS, drawing a near‑record crowd and showcasing Messi’s continued impact on the league’s global profile.

Australia and Japan signed contracts in Melbourne on April 19, 2026 for the first three of 11 warships in a $7 billion defence deal, aiming to deepen bilateral security cooperation amid a tightening regional threat environment.Defence Minister Richard Marles and his Japanese counterpart Shinjiro Koizumi announced the agreement at a ceremony for the new Mogami‑class stealth frigates.The so‑called “Mogami Memorandum” pledges tighter military ties, including closer industrial cooperation on future defence projects.Japan’s Mitsubishi Heavy Industries will construct three of the frigates in Nagasaki Prefecture, while Australian shipbuilder Austal will produce the remaining eight in Western Australia.The first Japanese‑built vessel is slated for delivery in 2029 and entry into service by 2030, bolstering Australia’s surface fleet – a capability Marles described as “more important than at any time in decades.”Koizumi warned that a “increasingly severe security environment” makes deeper defence coordination essential for both nations.Australia’s recent decision to award the contract to Mitsubishi followed a competitive bidding process that also involved Germany’s Thyssenkrupp.In parallel, Canberra has pledged a record $305 billion in military spending over the next ten years, part of a broader overhaul that seeks to raise defence outlays to 3 % of GDP by 2033, the highest level since World War II.Both countries, close allies of the United States and members of the Quad security forum, have accelerated cooperation in response to China’s expanding influence and broader shifts in the Asia‑Pacific security landscape.

UNICEF said it is outraged after Israeli forces killed two drivers it had hired to deliver clean water at the Mansoura water filling point in northern Gaza on Friday morning, prompting the agency to halt activities there and demand a thorough investigation.The incident occurred during routine water‑trucking operations; two additional people were wounded. UNICEF immediately suspended all work at the site and urged Israeli authorities to ensure full accountability for the attack.In a statement, UNICEF emphasized that “humanitarian workers, essential service providers, and civilian infrastructure, including critical water facilities, must never be targeted,” underscoring that protecting aid personnel is a binding obligation under international humanitarian law.Palestinian health authorities report that more than 750 Palestinians have been killed by Israeli forces since the U.S.–Qatar‑brokered cease‑fire began in October, while overall death tolls in the Gaza conflict exceed 72,000 since the war erupted on October 7, 2023.Separately, in the occupied West Bank, a 25‑year‑old Palestinian man, Muhammad Ahmad Suwaiti, was shot dead by Israeli forces in Khirbet Salama, according to the Palestinian news agency WAFA.The Israeli military described the West Bank incident as the elimination of a “terrorist who infiltrated the community of Negohot in Judea and Samaria,” without specifying the responsible party.Since the Gaza war began, Israeli forces and settlers have killed more than 1,060 Palestinians in the West Bank, according to the Palestinian Ministry of Health, highlighting the widening humanitarian crisis beyond Gaza.

Iran's Islamic Revolutionary Guard Corps (IRGC) Navy declared the Strait of Hormuz closed on Saturday, April 18, 2026, warning that any vessel attempting passage would be targeted. The announcement came less than 24 hours after the waterway had been briefly reopened, reigniting concerns over maritime security in the Persian Gulf and the broader U.S.-Iran standoff.The IRGC statement, relayed by Iran's Student News Agency, stipulated that the closure would remain in effect until the United States lifts its naval blockade on Iranian vessels and ports—a move Tehran labels a breach of the cease‑fire agreement linked to the ongoing U.S.-Israel conflict with Iran.Speaker of Iran's Parliament Mohammad Bagher Ghalibaf emphasized on television that “the Strait of Hormuz is under the control of the Islamic Republic,” condemning the U.S. blockade as “clumsy and ignorant.” Meanwhile, Supreme Leader Mojtaba Khamenei warned the navy was prepared to deliver “new bitter defeats” to its adversaries.Just hours earlier, Iranian Foreign Minister Abbas Araghchi had announced the strait “completely open for all commercial vessels,” prompting a brief surge of more than a dozen merchant ships and a dip in global oil prices. The sudden reversal underscores the volatility of the region’s energy markets, where even short‑lived openings can sway price benchmarks.According to the United Kingdom Maritime Trade Operations (UKMTO), Iranian gunboats fired on two commercial vessels, and India’s Ministry of External Affairs confirmed that two Indian‑flagged ships were involved in a “shooting incident.” Some merchant crews reported receiving radio warnings from the IRGC Navy that no ships would be permitted through the strait.U.S. President Donald Trump responded by stating Tehran could not “blackmail Washington” and warned that the naval blockade would “remain in full force” unless a cease‑fire deal is secured before its Wednesday deadline. Trump also hinted at ending the cease‑fire if Iran persists with the closure.Al Jazeera analysts described the situation as “two competing blockades,” noting that the brief reopening had raised hopes for a confidence‑building measure, only to revert to a stalemate. Correspondent Zein Basravi observed that the strait has become “the only space for engagement,” even if that engagement is hostile, serving as a platform for Iran to signal leverage to the United States.

The leaders of Mexico, Brazil, and Spain have pledged more aid to Cuba, while appealing for the island nation's sovereignty to be respected amid an ongoing pressure campaign from United States President Donald Trump.The joint statement on Saturday was released as leftist leaders from across the globe met in Barcelona. The three countries expressed great concern about the serious humanitarian crisis that the people of Cuba are going through.The US has imposed a trade embargo on Cuba since Cold War tensions emerged in the 1960s. But the Trump administration has ratcheted up pressure on the island's communist government, in an apparent attempt to prompt leadership change.Since January, Trump has barred the import of oil from Venezuela. He also threatened other countries with sanctions if they deliver oil to Cuba, leading to fuel shortages and energy blackouts.The campaign against Cuba's government follows similar pressure tactics against Venezuela's former President Nicolas Maduro, who was abducted and imprisoned in a US military operation on January 3.Trump, meanwhile, has floated the removal of Cuba's President Miguel Diaz-Canel.In Saturday's statement, the governments of Mexico, Spain, and Brazil — represented by President Claudia Sheinbaum, Prime Minister Pedro Sanchez, and President Luiz Inacio Lula da Silva, respectively — warned against any actions that run contrary to international law.“We are committed to coordinating an increase in our humanitarian response, aimed at alleviating the suffering of the Cuban people,” the trio said.While the statement did not directly reference the US, it called for respect for territorial integrity, sovereign equality, and peaceful settlement of disputes, as outlined in the United Nations Charter.

Pope Leo XIV has arrived in Angola, marking the third leg of his landmark African tour. The visit comes at a time of heightened tensions with US President Donald Trump, who has publicly criticized the Pope's stance on various issues, including the Middle East conflict. The Pope's visit to Angola is significant, as he is the third pontiff to do so, following John Paul II in 1992 and Benedict XVI in 2009. During his stay, he is expected to meet with Angola's President Joao Lourenco and deliver a speech to the nation, where approximately 44 percent of the population identifies as Catholic. The Pope's message of world peace and his warnings against corruption and exploitation are likely to resonate deeply in Angola, a country that emerged from a 27-year civil war in 2002. About one-third of Angola's population lives below the poverty line, despite the country's vast fossil fuel reserves. Throughout his Africa visit, Pope Leo has been vocal about his concerns regarding corruption, the exploitation of resources, and the dangers of artificial intelligence. His statements have drawn attention and sparked discussions globally, particularly in the context of his public disagreements with President Trump. The clash between the Pope and Trump escalated when Trump called the Pope 'weak on crime' and 'terrible for foreign policy'. The Pope responded by stating he was not afraid of Trump and would continue to speak out against war. This public exchange marks a rare instance of a pontiff and a sitting US president engaging in a public dispute. During his visit, the Pope will also celebrate an open-air Mass in Kilamba and travel to Muxima and Saurimo for further engagements. His 18,000km African tour will conclude in Equatorial Guinea.