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Researchers at Rothamsted Research in Harpenden, Hertfordshire, have made a groundbreaking discovery in the field of food safety. By utilizing Crispr genome editing, they have successfully developed wheat that can be used to make bread with reduced levels of acrylamide, a toxic compound classified as a probable carcinogen.The innovation lies in the reduction of free asparagine, an amino acid in wheat that converts into acrylamide when bread is toasted, fried, or baked. Field trials over two years demonstrated that gene-edited wheat can have significantly lower concentrations of free asparagine without impacting crop yields. This translates into lower acrylamide formation in food products, making toasted bread safer for consumption.In tests, bread and biscuits made from the edited wheat showed substantially reduced acrylamide levels, with some bread samples having concentrations below detectable limits even after toasting. The Crispr editing targeted the gene responsible for asparagine production, achieving a reduction of up to 93% in free asparagine in dual-edited lines.Compared to conventional methods that achieved a 50% reduction in free asparagine but resulted in a 25% yield penalty, the Crispr-edited wheat offers a more efficient and effective solution. Dr. Navneet Kaur, a lead researcher, highlighted the potential of Crispr technology to deliver precise, beneficial changes in crop genetics, emphasizing the importance of supportive regulatory frameworks to unlock benefits for agriculture and food systems.The UK has become a global hub for gene editing research since Brexit, with the Genetic Technology (Precision Breeding) Act of 2023 facilitating the development and marketing of genetically modified crops. However, the future of these advancements may be influenced by negotiations with the EU over sanitary and phytosanitary agreements.Prof. Nigel Halford, who led the study, noted that low-acrylamide wheat could help food businesses meet safety standards without compromising product quality or incurring major costs, ultimately reducing consumers' dietary exposure to acrylamide.

Aaron Ramsey has confirmed his retirement from professional football at the age of 35, ending a career that saw him feature for Arsenal, Juventus, Nice, Cardiff City and Rangers before becoming a free agent after leaving Mexican side Pumas last year.Ramsey earned 86 caps for Wales, with his final appearance coming in 2024. A string of injuries and reduced minutes saw him omitted from Wales' World Cup qualifying playoff against Bosnia and Herzegovina, a defeat that effectively closed the door on any chance of a major tournament finale.In an emotional Instagram post, the midfielder wrote, "This has not been an easy decision to make. It has been my privilege to wear the Welsh shirt and experience so many incredible moments in it. I owe a debt of gratitude to the managers and staff who helped me along the way." He also thanked the "Red Wall" – Wales' passionate supporters – for their unwavering backing.Ramsey further expressed appreciation for the clubs that shaped his journey, stating, "Thank you to all the clubs I’ve been lucky enough to play for, and to the managers and staff who made it possible for me to live my dream at the highest level."His trophy cabinet includes three FA Cup medals with Arsenal, a Serie A title (2020) and Coppa Italia (2021) with Juventus, and a Scottish Cup with Rangers in 2022, underscoring a decorated career across England, Italy and Scotland.

Effective September, the UK will limit interest on Plan 2 and Plan 3 student loans to 6%, announced by ministers amid growing concerns that higher inflation could push repayments sharply higher for graduates.Currently, borrowers on Plan 2 pay an interest rate equal to the Retail Prices Index (RPI) – presently 3% – plus up to an additional 3% once they earn more than £29,385. While studying, both Plan 2 and Plan 3 loans already attract RPI + 3%.Plan 2 loans cover undergraduate courses and Postgraduate Certificates of Education taken out since 1 September 2012 in Wales and between that date and 31 July 2023 in England. Plan 3 loans apply to postgraduate master’s or doctoral programmes for borrowers in England and Wales.Skills Minister Jacqui Smith linked the decision to global instability, noting that “the conflict in the Middle East is causing anxiety at home… Capping the maximum interest rate will provide immediate protection for borrowers, supporting those most exposed within this already unfair system.”The repayment threshold will remain frozen at £29,385 for the next three years, until 2030, a policy that could raise annual repayments by up to £300 for many graduates.Labour MPs have pressed the government to reconsider this freeze, arguing it will erode real‑term earnings as the threshold approaches the minimum wage by 2030.National Union of Students president Amira Campbell welcomed the cap as “a huge win” for the more than 5 million people on Plan 2 loans, but warned that “the change cannot come alone” and called for a rise in the repayment threshold in line with incomes.Prime Minister Keir Starmer has pledged to explore ways to make the student‑loan system fairer, echoing criticism from Conservative leader Kemi Badenoch, who described the scheme as a “debt trap” at “breaking point”.

Harry Styles has announced the full programme for this year’s Meltdown Festival at the Southbank Centre, positioning the pop star as curator of a multi‑genre celebration that runs from 11 June to 21 June. In addition to headlining a solo show on 16 June at the Royal Festival Hall, Styles will perform amid his ongoing Wembley Stadium tour, while the festival showcases a broad spectrum of talent ranging from jazz to electronic dance music. The jazz segment features two sets by acclaimed US saxophonist Kamasi Washington: one dedicated to his album Fearless Movement and another titled “Jazz Legends Reimagined,” where he will reinterpret classic jazz compositions. Ethiopian‑born pioneer Mulatu Astatke returns after a farewell‑tour appearance, and the UK scene is represented by drummer Yussef Dayes and reed virtuoso Shabaka, who will join a collective of collaborators. Indie and rock offerings include LA band Warpaint (performing their sole gig of the year), British singer‑songwriter Nilüfer Yanya, and a mix of emerging and veteran acts such as Bar Italia, Stephen Fretwell and Getdown Services. Former Maccabees frontman Orlando Weeks will deliver a hybrid set of music and storytelling, while Devonté Hynes (known as Blood Orange) will present a classical‑inspired performance with musicians Adam Tendler, Cæcilie Trier and Tariq Al‑Sabir. On the pop front, rising stars Erika de Casier and Fousheé will provide some of the season’s most forward‑thinking tracks. The electronic roster spans ambient pioneer Beverly Glenn‑Copeland, an improvised collaboration featuring Jon Hopkins, Maddie Ashman and Leo Abrahams, high‑tempo EDM from Australia’s Ninajirachi, and a DJ set by James Murphy of LCD Soundsystem. A parallel programme of free, family‑friendly events will showcase “a mix of appearances from Styles’ favourite artists beyond music,” according to the Southbank Centre. Speaking about the festival, Styles said: “Music is my life; every artist involved in this year’s Meltdown festival means so much to me, both as a fan, and a musician. It’s a true honour to host legends who have paved the way for the generations that follow them, as well as new acts that have inspired me to push my creative boundaries.” Tickets become available on 9 April for Southbank members and 10 April for the general public, with the event promising a unique blend of established icons and cutting‑edge talent.

The conflict in Iran has underscored how fragile a world built on fossil fuels truly is, with disruptions to oil, gas and fertilizer shipments adding millions of tonnes of greenhouse‑gas emissions to an already critical climate system.While Saudi Arabia and other petrostates blocked any mention of a fossil‑fuel phase‑out at the UN COP30 summit last November, a new diplomatic effort is gathering momentum outside the UN framework.On 28‑29 April, Colombia will host the First International Conference on the Just Transition Away from Fossil Fuels. Unlike UN negotiations, the summit will be decided by majority vote, preventing a handful of countries from derailing progress.The event is co‑sponsored by Colombia – the world’s fifth‑largest coal exporter – and the Netherlands, home to Royal Dutch Shell. Organisers have invited nations that supported the COP30 roadmap, as well as sub‑national leaders such as California Governor Gavin Newsom, a potential 2028 U.S. presidential contender.Delegates, described as a “coalition of the willing”, will share concrete plans to shift their economies away from fossil fuels while safeguarding workers and communities. Climate activists, Indigenous representatives and trade‑union leaders will also contribute ideas for turning the abstract goal of decarbonisation into actionable policy.One focal point will be the reduction of the $7 trillion per year in global fossil‑fuel subsidies, a figure that the International Energy Agency warns could be trimmed without harming the livelihoods that depend on these funds. UN Secretary‑General António Guterres has urged the International Energy Agency to create a platform that aligns the decline of fossil‑fuel investment with rapid clean‑energy expansion.The real leverage of this coalition lies in its economic weight. The 85 countries that backed the COP30 roadmap together account for a gross national product of $33.3 trillion—surpassing the United States’ $30.6 trillion and far exceeding China’s $19.4 trillion.If the Just Transition conference produces a credible, market‑oriented plan, it could send a clear signal to investors and policymakers that the era of oil, gas and coal is ending, prompting a reallocation of capital away from stranded‑asset risks.Adding California’s $4.1 trillion GDP to the coalition’s total would create an economic bloc of roughly $37.4 trillion, approaching the combined $50 trillion output of the United States and China.Newsom has repeatedly positioned California as a climate leader, noting that two‑thirds of the state’s electricity now comes from non‑carbon sources and that its economy has risen from the world’s sixth to fourth largest. He pledged that California will fill the void left by the United States’ retreat from the Paris Agreement by competing in global green‑technology markets.Public opinion supports such a shift: between 80 % and 89 % of the world’s population wants stronger climate action. The upcoming conference therefore represents a pivotal chance to translate widespread demand into a coordinated, economically powerful push for a fossil‑fuel‑free future.

The Artemis II mission has achieved a remarkable feat, with the crew flying further from Earth than any human before them, reaching a distance of 406,778km (252,760 miles) from Earth. This historic moment broke a 56-year-old record set by the Apollo 13 mission.During their six-hour lunar flyby, the crew captured unprecedented views of the moon's far side, providing a human perspective on features previously only known through robotic photographs. The astronauts used high-powered Nikon cameras and their iPhones to document the lunar surface, with plans to return with thousands of pictures, including images of the Apollo 12 and 14 landing sites.The mission also included an emotional moment when the crew honored the legacy of past astronauts. They began the day with a wake-up message from Jim Lovell, the Apollo 13 commander, who recorded the message two months before his death. Lovell welcomed the crew to 'my old neighborhood' and encouraged them to enjoy the view.In a touching gesture, the astronauts named two fresh lunar craters. They proposed the names Integrity for their capsule and Carroll, in honor of Commander Reid Wiseman's late wife who passed away from cancer in 2020. Wiseman, a former fighter pilot, has been raising their two daughters on his own since then. The names will be passed along to the International Astronomical Union for official designation.The mission's free-return lunar trajectory took advantage of gravity from the Earth and moon, reducing the need for fuel. This figure-of-eight path will put the astronauts on course for home once they emerge from behind the moon. As they passed across the far side of the moon, the capsule experienced a 40-minute communications blackout, a routine occurrence during the Apollo missions.Canadian astronaut Jeremy Hansen challenged future generations to make sure the record broken by Artemis II is not long-lived. The crew's achievements and emotional moments highlight the significance of this mission in the history of space exploration.

Michigan secured its second national crown — the first since 1989 — by edging UConn 69‑63 in a gritty Final Four showdown that tested both teams’ resolve. Despite making only two three‑pointers all night (a 2‑for‑15 effort from beyond the arc), the Wolverines leaned on disciplined defense and a flawless free‑throw line, converting 25 of 28 attempts in the closing minutes. Elliot Cadeau emerged as the game’s catalyst, pouring in 19 points, including Michigan’s inaugural three‑point basket of the night 7:04 into the second half. His performance earned him the Most Outstanding Player honor for the Final Four. The decisive blow came when freshman Trey McKenney sank the Wolverines’ second three‑pointer with 1:50 remaining, extending the lead to nine points and forcing UConn into a frantic chase. UConn fought back valiantly; Solo Ball knocked down a three‑pointer with 37 seconds left to trim the deficit to four, and senior guard Alex Karaban added 17 points. However, missed free throws and a sub‑31% field‑goal percentage (30.9%) hampered the Huskies’ comeback. Injured graduate transfer Yaxel Lendeborg contributed 13 points on 4‑for‑13 shooting despite a sore knee and foot, while UConn’s leading scorer Braylon Mullins struggled, finishing 4‑for‑17 from the floor. Coach Dan Hurley watched his squad battle foul trouble and a cold shooting night, ultimately seeing the trophy travel to Ann Arbor instead of Storrs. Michigan closed the night with a 37‑3 record, capping a tournament run that had previously featured five straight 90‑point blowouts — a contrast to the defensive, low‑scoring finale that delivered the program’s long‑awaited championship.

When Elle Middlemas turned 18, she began wondering whether she owned a Child Trust Fund (CTF) – a government‑backed savings account created for children born between 1 September 2002 and 2 January 2011. Her search hit a dead end; she could not confirm if she was entitled to any money and an email to HMRC yielded no response.Middlemas, a Whitby college student, explained that the loss of her mother at age 11 left her with little guidance. “My sister is 21 and spent three years looking for a fund and found nothing, so we assumed we didn’t have one,” she said, expressing the frustration felt by many of her peers.She and her sister are part of an estimated 758,000 people aged 18‑23 who have unclaimed CTFs. Collectively, these dormant accounts hold roughly £1.5 bn, a substantial sum that disproportionately belongs to low‑income families who are often unaware of its existence.Advocates are now pressing the government to automatically release CTFs when holders reach 21 years of age. Experts estimate that such a policy could inject up to £286 m directly into the pockets of young people who need it most.Middlemas finally learned of her entitlement after a conversation with a friend’s parent six months after her birthday. She discovered the Share Foundation, a charity that helps reconnect youths with their funds, and located a NatWest account bearing her name.“I had £700 sitting in my bank and thought, ‘What is going on?’ My sister also had one but never knew how to access it,” she recalled. The sisters plan to use the money to support university expenses and repay debts, underscoring the tangible impact of the scheme.The CTF programme was launched by the Labour government in 2005 to encourage parental savings. Every child received a £250 government contribution, with an additional £250 for those from low‑income families or in local authority care. Parents could add up to £9,000 per year, and any investment gains accrued until the child turned 18.If a parent failed to open an account within 12 months of birth, HMRC would create one on the child’s behalf. Today, the average value of a CTF stands at about £2,200.More than two‑thirds of the six million original recipients are now over 18 and eligible to claim their funds, with HMRC‑allocated accounts representing 28 % of all CTFs.Geographically, the North‑East of England has the highest concentration of HMRC‑allocated accounts, totalling £48 m. Across the UK, youths from the most disadvantaged 15 % of families hold accounts averaging £2,900 in value.Gavin Oldham, chief executive of the Share Foundation, warned that the scheme is hampered by poor communication, limited financial education, and “policy neglect”. He indicated the charity is considering a judicial review to compel the government to release the unclaimed assets.Oldham noted that the charity has already linked “well over 100,000 accounts to young adults”, yet the “sheer quantum of these unclaimed accounts remains a major problem”.“It is strange to find a government which expresses concern over youth poverty while doing so little to deliver on a groundbreaking scheme,” Oldham added.The charity’s proposal to release HMRC‑allocated funds automatically at 21 would free roughly £500 m, including £350 mOldham cautioned that a legal challenge, while potentially successful, could delay payouts for years, leaving vulnerable youths “denied their birthright for far too long”.Beyond immediate release, the Share Foundation is urging the creation of a new, targeted scheme for low‑income youths that embeds a financial‑awareness component, allowing participants to top up their funds through education‑linked incentives.Labour MP Laura Kyrke‑Smith echoed these concerns, describing the CTF system as “confusing and opaque” and calling for proactive tracing of account holders and clearer public information.HMRC responded that it is “directly sending every eligible young person information to help them find their child trust fund”, while also raising awareness via social media, broadcast interviews, and an online tracing tool. The agency added that banks, building societies, and investment firms managing the funds share responsibility for communicating with account holders.

Manchester City's long-serving captain, Bernardo Silva, will be departing the Premier League club at the end of the current season. This confirmation comes from assistant manager Pep Lijnders, following City's convincing 4-0 FA Cup quarterfinal victory over Liverpool on Sunday. Lijnders reflected on Silva's impending exit, stating, 'Every good story comes to an end.' He expressed his hope that Silva will enjoy his final months with the club and receive a fitting farewell, highlighting that he 'deserves all that attention.' The 31-year-old Portuguese midfielder, who has been an integral part of Manchester City since joining from AS Monaco in 2017 for approximately $57.35 million, will be leaving as a free agent upon the expiration of his contract. During his nine-year tenure at the Etihad Stadium, Silva has secured six Premier League titles and the Champions League, making 450 appearances for the club. Silva's versatility, exceptional technique, and relentless work ethic have made him a cornerstone of City's success under Pep Guardiola, who has previously described him as 'irreplaceable.' Manchester City are still in contention for a domestic treble, currently trailing Premier League leaders Arsenal by nine points, although they do have a game in hand and eight matches remaining to bridge the deficit. Silva's departure follows in the footsteps of another high-profile exit, as Liverpool's Mohamed Salah also announced his departure at the end of the season, marking a significant change for top Premier League clubs.