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Malina Lee, a 31‑year‑old wedding baker from San Antonio, joined TikTok in 2020 to pass the lockdown‑induced boredom and promote her business. Four years later, an anonymous commenter called “PickleFart” noticed an asymmetrical neck in one of her videos and suggested she check for a goiter.The tip proved accurate: doctors confirmed thyroid cancer. Lee received prompt treatment and, within a year, was declared cancer‑free. She told the outlet that her oncologist was amazed at how early the disease was caught, crediting the TikTok comment as the catalyst.Lee’s experience is part of a growing trend where TikTok’s hyper‑targeted algorithm surfaces health‑related content that resonates with users’ unnoticed symptoms. In several cases, community members have flagged potential conditions that clinicians initially missed.The “PickleFart” persona belongs to Billie Jean Tuomi, who calls herself the “thyroid avenger.” A thyroid‑cancer survivor herself (diagnosed in 2012), Tuomi now scans videos for neck asymmetry and gently advises creators to seek a thyroid panel—a blood test measuring hormone levels and antibodies. The American Thyroid Association recommends adults start routine thyroid testing at age 35, or annually for high‑risk individuals.Tuomi estimates she has flagged dozens of videos, with at least four confirmed serious thyroid issues, including Lee’s. She stresses she does not claim to diagnose, merely urges viewers to consult a physician. After a viral comment, she received a flood of private messages with neck photos, prompting her to change her username.Lee, inspired by Tuomi’s intervention, has begun commenting on other users’ videos, helping one individual discover an enlarged thyroid that required removal. She describes the process as a “domino effect” of community‑driven health awareness.Medical professionals acknowledge the double‑edged nature of this phenomenon. Craig Mittleman, director of emergency services at Lawrence + Memorial Hospital, notes a rise in patients arriving with self‑diagnoses sourced from social media. While this can empower patients to ask informed questions, it also burdens clinicians with debunking misinformation.Gender disparities amplify the issue: research shows women are more likely to seek health information online, often after feeling dismissed by traditional providers. TikTok user Tori Mosser, a 23‑year‑old filmmaker, credits a direct message suggesting chronic appendicitis for prompting surgery that resolved her chronic vomiting episodes.Both Lee and Mosser emphasize the therapeutic value of finding a supportive community on TikTok, especially for invisible or chronic illnesses that are frequently minimized in clinical settings.

The collapse of talks between the US and Iran has sent shockwaves through global markets, fuelling fears of a prolonged energy crisis and rising inflation. The failure to reach a peace deal has left large numbers of oil tankers stuck in the Persian Gulf, with oil prices fluctuating wildly in response to the uncertainty.US Vice-President JD Vance has blamed the collapse of the talks on Tehran's refusal to abandon its nuclear weapons programme, while Iranian sources have hit back at what they describe as 'excessive' demands from Washington. The stalemate has raised concerns about the long-term impact on the global economy, with governments and central banks warning of higher inflation and interest rates.Mohamed El-Erian, an adviser to Allianz, has cautioned that uncertainty will continue to dominate assessments of the financial impact from the conflict. 'Absent a swift resumption of negotiations, the immediate reaction of financial markets when they open for the trading week will be to push oil prices higher and borrowing costs higher,' he said.The International Monetary Fund and World Bank's spring meetings in Washington will focus on the war's impact on the global economy, with the IMF's managing director, Kristalina Georgieva, indicating that the fund will present three scenarios predicting lower economic growth and higher inflation. The IMF is also expected to highlight the impact on vulnerable economies.In the short term, oil prices have ended the week lower, with Brent crude at $94.26 a barrel and West Texas Intermediate crude at $95.63 a barrel. However, global stock markets have rebounded after a temporary ceasefire was announced, with the S&P; 500 close to its level before the US-Israeli attacks on Iran began.

The United States’ senior envoy, Vice President JD Vance, said the marathon talks in Islamabad collapsed because Iran would not abandon its nuclear weapons programme, a stance Tehran’s representatives dismissed as a lack of US goodwill. Vance, who departed Islamabad on Sunday after a 21‑hour session with Iranian officials, reiterated that Washington’s red lines required an "affirmative commitment" from Tehran that it would not pursue a nuclear weapon or the means to acquire one quickly. He described the stalemate as "bad news for Iran much more than it is for the United States." Iranian parliament speaker Mohammad Bagher Ghalibaf countered that, despite offering "constructive initiatives," the US failed to win the trust of the Iranian delegation, leaving it to Washington to decide whether it can regain that confidence. Iran’s foreign ministry downplayed expectations, stating that no one anticipated a deal in a single session and emphasizing continued regional contacts, while the semi‑official Tasnim news agency blamed "excessive" US demands for the impasse. The talks took place under a 14‑day ceasefire agreed by the US, Iran and Israel, with Pakistan’s foreign minister Ishaq Dar urging both sides to honour the pause and offering to facilitate renewed dialogue. The conflict, which began on 28 February, has already claimed over 3,000 lives in Iran, more than 2,000 in Lebanon, and dozens across the Gulf region, while inflicting extensive infrastructure damage. Israeli security cabinet minister Ze’ev Elkin warned that Iran is "playing with fire," even as he left the door open for further negotiations. These were the first direct US‑Iran talks in more than a decade and could determine the fate of the fragile ceasefire and the reopening of the Strait of Hormuz—a chokepoint for roughly 20 % of global energy supplies. The war has already sent international oil prices soaring. In addition to Vance, US special envoy Steve Witkoff and former President Trump’s son‑in‑law Jared Kushner met with Ghalibaf and Iranian foreign minister Abbas Araghchi for two hours before a brief recess. The Iranian delegation arrived in black mourning attire for the late Supreme Leader Ayatollah Ali Khamenei and carried shoes and bags belonging to children killed in a school bombing near a military compound—a strike the Pentagon says is under investigation, with some reports suggesting US involvement. Pakistani security forces sealed off Islamabad, a city of over two million, underscoring Pakistan’s newly prominent mediating role after a year of diplomatic isolation. The US military announced it was "setting conditions" to clear mines and allow warships to pass through the Strait of Hormuz, a claim Iran’s state media denied. Prior to the talks, a senior Iranian source told Reuters that the US had agreed to release frozen Iranian assets held in Qatar and other banks, a statement the US later denied. Tehran’s broader demands include control over the strait, payment of war reparations, a region‑wide ceasefire—including in Lebanon—and the collection of transit fees from shipping traffic. President Trump’s minimum objectives remain the free passage of global shipping through the strait and the crippling of Iran’s nuclear enrichment capability to prevent the development of an atomic bomb.

This week Anthropic revealed that its latest AI system, dubbed Mythos, is so powerful that the company will not make it publicly available, arguing that the potential risks outweigh commercial incentives.U.S. Treasury Secretary Scott Bessent convened senior banking executives to discuss the implications of the model, underscoring growing governmental concern over advanced AI capabilities.In the United Kingdom, Reform MP Danny Kruger wrote to the government urging an immediate dialogue with Anthropic, warning that Claude Mythos could pose "catastrophic cybersecurity risks" to the nation.Critics such as AI researcher Gary Marcus questioned the hype, suggesting that Anthropic’s co‑founder Dario Amodei may possess strong technical skills but is "graduated from the same school of hype and exaggeration" as OpenAI’s Sam Altman.Beyond the policy debate, Anthropic has mounted a striking media offensive. The startup secured a 10,000‑word profile in the New Yorker, two feature pieces in the Wall Street Journal, and a Time magazine cover that placed founder Amodei alongside the Pentagon and U.S. Defense Secretary Pete Hegseth.Co‑founder Jack Clark and Amodei appeared on separate New York Times podcasts, fielding questions about machine consciousness and the model’s potential to "rip through the economy." Their "resident philosopher" even discussed with the WSJ whether Claude, Anthropic’s commercial product used for cryptocurrency trading and missile‑target designation, possesses a "sense of self."Anthropic’s public‑relations lead, Danielle Ghiglieri, celebrated the coverage on LinkedIn, describing the Time cover as a "mad dash" that finally let the company tell its own story.However, the company’s PR triumphs have not been without missteps. In early April, Anthropic inadvertently released part of Claude’s internal source code, though it assured that no customer data or credentials were exposed.Experts remain skeptical about the unverified claims surrounding Mythos. Dr. Heidy Khlaaf of the AI Now Institute warned that the vague marketing language could be an attempt to attract investment without substantive scrutiny.Cybersecurity specialist Jameison O’Reilly acknowledged the model’s novelty but downplayed Anthropic’s assertion of discovering "thousands of zero‑day vulnerabilities," noting that in a decade of offensive operations, zero‑days were rarely needed to achieve objectives.Anthropic also faces operational constraints. The firm has imposed usage caps on its popular Claude model and now requires customers to purchase additional compute capacity for third‑party tools, suggesting that infrastructure limitations may be a practical reason for withholding Mythos.As the race to dominate the emerging AI market intensifies, Anthropic’s strategy appears to blend genuine safety concerns with a calculated publicity push, positioning Mythos as a strategic signal that the company remains "open for business" while keeping the technology under tight control.

The United States and Iran have initiated direct talks in Islamabad, Pakistan, in an effort to bring an end to their six-week conflict. These face-to-face discussions, confirmed by the White House, follow a recent fragile ceasefire agreement and separate bilateral meetings with Pakistani Prime Minister Shehbaz Sharif. The US delegation, led by US Vice President JD Vance, includes special envoy Steve Witkoff and Jared Kushner, son-in-law of President Donald Trump. The Iranian delegation, comprising over 70 people, is headed by parliamentary Speaker Mohammad Bagher Ghalibaf and Foreign Minister Abbas Araghchi. According to Iranian state media, the talks proceeded after Iranian preconditions were met, including a reduction in Israeli attacks on Lebanon. Iran had insisted on the inclusion of Lebanon in the ceasefire and the lifting of US sanctions as prerequisites for the negotiations. Pakistani Prime Minister Sharif expressed hope that these talks would serve as a stepping stone toward durable peace in the region. Despite earlier assertions from Tehran that they would not engage without commitments on Lebanon's inclusion and US sanctions, the negotiations have moved forward. Sources indicate some progress on basic conditions, including the need for a ceasefire in Lebanon, with reports of a possible understanding to limit strikes to southern Lebanon. There are also indications of potential movement on the unfreezing of Iranian assets. US President Donald Trump posted on social media that the only reason Iranian officials were alive was to negotiate a deal, stating that Iran had no cards other than short-term extortion. Vance expressed optimism about a positive outcome but warned that the negotiating team would not be receptive if Iran tried to play them.

The new academic term began in Gaza in late March, but the usual bustle of students catching buses to campus has been replaced by the stark reality of displacement.Israel’s relentless campaign has turned most university buildings into rubble and shelters, forcing a shift to online learning that many students in tents cannot access due to lack of electricity, water, food and reliable internet.Against this backdrop, a glimmer of hope has emerged. In the overcrowded al‑Mawasi district of Khan Younis, the US‑based NGO Scholars Without Borders has erected a makeshift “University City,” a wooden and metal structure designed to bring students back into a real lecture hall."Our mission is to bring education closer to students in a better environment," said Hamza Abu Daqqa, the organisation’s Gaza representative.The facility houses six halls that can accommodate up to 600 students each day. Powered by solar panels, it offers internet access, improvised green spaces and even a small business incubator to help students explore entrepreneurial ideas.University City operates on a rotating weekly schedule, allocating each day to a different institution so that multiple universities can share the limited space. Priority is given to courses that require hands‑on instruction, such as practical labs and discussion‑based classes.Prominent Gaza institutions—including the Islamic University, Al‑Azhar University and the Palestine College of Nursing—have already begun using the site.For many students, this is the first time in years they have set foot in a space that feels like a real university. "When I saw this place, I was amazed," said 20‑year‑old nursing student Mariam Nasr, who fled Rafah and now travels four kilometres on foot to attend classes.Another first‑year student, Amr Muhammad, echoed the sentiment: "Being here with other students, discussing and engaging in class makes a huge difference."The broader picture remains grim. UN experts have labeled Israel’s systematic targeting of Gaza’s academic sector as “scholasticide.” More than 7,000 university students and staff have been killed or injured, and over 60 university buildings have been completely demolished, according to the Euro‑Med Human Rights Monitor.Materials for University City were sourced entirely within Gaza, a testament to the community’s resilience amid soaring costs and scarce resources. Yet the initiative is hampered by the same blockade that restricts reconstruction supplies, fuel and safe transport.Students still face daily hurdles: damaged roads, limited cash, and unreliable transport—often relying on worn‑out vehicles, donkey carts or long walks. "My father could only give me eight shekels (about $2.64) for a ride," Mariam explained, highlighting the economic strain.Even once inside the halls, challenges persist. Power outages and unstable internet make it difficult to print materials or follow online lectures, forcing many to rely on old phones and intermittent connections.Nevertheless, the atmosphere inside University City is one of determination. "For medical education, in‑person learning is essential," said Dr Essam Mughari of the Palestine College of Nursing. "Seeing students gather again restores something vital."For students like Mariam, the drive to continue studying is deeply personal. "My cousin, a nurse, was killed when an airstrike destroyed her family’s house. I study to heal others and honor her memory," she said.While University City now serves hundreds daily, thousands of Gaza’s students remain without comparable facilities. Abu Daqqa stresses that the project is only the beginning: "We have built dozens of makeshift schools, but the need is far greater. Imagine what could be done if the needed resources were allowed through."

At least seven Palestinians have been killed and others wounded in Israeli strikes across the central and southern Gaza Strip. An Israeli drone fired two missiles close to a police post in Bureij refugee camp in central Gaza, killing and wounding several people.Medical sources confirmed the early morning attack to Al Jazeera, saying the strike hit a group of civilians in the 'Block 9' area of Bureij. Several people were killed and seriously wounded, they said.Ambulance crews faced difficult conditions as they worked to transport the bodies and those injured to nearby hospitals, the sources added. The al-Aqsa hospital in central Gaza received six bodies and seven wounded people, including four in critical condition.Separately, in the southern Gaza Strip, Nasser Medical Complex received three wounded people following an Israeli drone strike against a tent of displaced people in the town of Bani Suheila, located east of Khan Younis.Al Jazeera's correspondent on the ground also reported Israeli artillery shelling and heavy tank fire near Bani Suheila and east of Gaza City.Israel's genocidal war on Gaza has killed more than 72,300 people since it began in October 2023, according to the Gaza Ministry of Health, including at least 738 since the so-called ceasefire went into effect last October.The tally includes at least 32 deaths since the start of April alone – among them Al Jazeera journalist Mohammed Wishah, who was killed in an attack west of Gaza City earlier this week.United Nations human rights chief Volker Turk condemned Israel's recent violence in the Gaza Strip, saying that 'the unrelenting pattern of killings' reflects Israel's 'sweeping impunity'.Meanwhile, in the occupied West Bank, Israeli settlers and forces stormed homes and villages throughout the morning, continuing an escalating campaign to expand their illegal settlements.

The online prediction market platform Polymarket has seen a surge in users betting on global events, including war and politics. With over $500,000 staked on whether Russia will capture Kostyantynivka, Ukraine, and millions more bet on the US-Iran conflict, the platform's influence is growing.Users, often anonymous and operating in groups on messaging apps like Discord, debate and strategize on how to profit from these events. Some critics argue that this gamification of war is immoral and can lead to manipulation of broader markets.Polymarket views itself as a source of truth, providing data on the future by allowing the public to bet on it. The platform has gained attention from major investors, including the Intercontinental Exchange, which has invested up to $2bn.However, concerns arise about the platform's decision-making process, which relies on an anonymous group of people holding a cryptocurrency token called UMA. This has led to disputes over the outcome of events and accusations of corruption.Experts warn that Polymarket's influence could extend beyond the platform, potentially manipulating larger markets and affecting institutions and pension funds.

Historic peace talks between Iran and the US commenced in Islamabad, Pakistan, marking the first face-to-face meeting between senior negotiators from both countries since 1979. The discussions, facilitated by Pakistani mediators, took place in a positive atmosphere despite continued fighting in Lebanon.The US delegation, led by Vice-President JD Vance, and Iran's negotiators, headed by Mohammad Bagher Ghalibaf and Abbas Araghchi, engaged in two rounds of talks. The discussions covered key topics such as security, finance, and the Strait of Hormuz.Pakistani sources confirmed that Pakistan's army chief, Asim Munir, was present in the room, having played a crucial role in brokering a ceasefire earlier in the week. Pakistan's Prime Minister, Shehbaz Sharif, hosted dinner for the delegations at his residence.The Iranian negotiators initially demanded a ceasefire in Lebanon, reparations, and a commitment to unblock frozen assets as part of a peace deal. However, the US warned against attempts to manipulate the negotiations, with Vance stating that the US would not be receptive to such tactics.The talks have sparked optimism, with a senior Pakistani official expressing hope for a breakthrough. The discussions have also drawn attention from other countries, with reports suggesting that China may offer guarantees to secure a deal.Meanwhile, Israel's military actions in Lebanon have escalated tensions, with Hezbollah firing rockets at Israeli cities. The Lebanese army has deployed troops to maintain stability amid internal tensions.