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The Politicization of Science Donald Trump’s war on science has been vicious and hugely damaging, but it is worth noting that he has lost some of its biggest battles. Last year, Mr Trump demanded that US federal scientific and medical research funding be cut by about half. But the budget Congress passed in February actually delivered a slight increase in overall funding – although specific Trump targets such as the Centers for Disease Control and Prevention were cut. Resistance from Congress He also continues to chip away at science in other ways such as dismissing the board overseeing the National Science Foundation this week. Maga’s attacks on science have been nakedly political. Its defeats have been politics of a different sort, showing that the bipartisan pro-science consensus is still intact, and for the moment has the power to hold Mr Trump in check. A Global Trend What is happening in the US is not unique. Wherever rightwing populists triumph, science is likely to suffer. Jair Bolsonaro’s rule in Brazil saw him attack scientists and cut environmental funding. In India, Narendra Modi’s Hindu nationalist government purged the theory of evolution from school textbooks. In Britain, Reform UK has already attempted local government cuts, targeting net zero spending. The Changing Role of Scientists Scientists have tended to avoid party politics for a specific reason. Historians identify an implicit scientific social contract that emerged in western states after the second world war, which established the state as the main funder of research, but in theory discouraged direct political interference by government. Many scientists believe that engaging in politics endangers this compact: if scientists don’t bother politics, it won’t bother them. A New Era for Science and Politics Scientists are no longer just defending funding. They are defending the idea that science should be independent of politics. What scientists gain by organising protests, speaking to the public through their academies and now running for office is a better understanding of the changing public sphere that they are part of. The public may gain an ally against rightwing populism – and a deeper, more serious engagement with the scientific challenges facing society. Mr Trump set out to tame scientists. He may have politicised them instead.

The Journey from Prototype to ClearanceBuilding a medical device is fundamentally different from standard software development. This week on Build Mode, host Isabelle Johannessen sat down with Robhy Bustami, co-founder and CEO of BioticsAI, to discuss the arduous path from a $100,000 prototype to FDA clearance. Bustami, a Startup Battlefield winner, detailed how his team is building an AI copilot for ultrasound designed to detect fetal abnormalities. The conversation revealed that the traditional startup mantra of 'move fast and break things' is obsolete in the medical sector, replaced by a necessity for extreme precision and coordination.Market Validation and Resource AllocationThe episode provides a strategic look at the 'data' driving medtech success. BioticsAI's recognition as a Startup Battlefield winner serves as a key validation of their technology's potential. However, Bustami emphasized that the primary data point for founders is not just market traction, but the successful navigation of complex regulatory pathways. This requires a significant reallocation of resources—shifting focus from rapid feature deployment to ensuring safety, reliability, and compliance with FDA standards.Shifting the MedTech CultureThe core impact of this discussion lies in the cultural shift it highlights for the industry. As timelines for FDA approval remain uncertain, the ability to maintain team morale and investor confidence becomes a critical operational metric. Bustami noted that building in a regulated industry requires a foundation of trust rather than speed. This signals a broader trend where medtech startups must balance the pressure of hyper-growth with the ethical and legal responsibilities of patient safety.The Future of AI in Healthcare RegulationLooking ahead, the medtech landscape will likely see a consolidation of companies that prioritize long-term compliance over short-term hype. As more AI copilots enter the market, the winners will be those founders who master the art of 'slow and steady' innovation. The next wave of medical breakthroughs will depend not just on algorithmic superiority, but on the ability to build sustainable organizations capable of weathering the regulatory storm.

Britain faces a paradox: voters are demanding more support as living costs rise, yet the Treasury is hemmed in by bond‑market discipline that pushes gilt yields above 5%. This tension is at the heart of why the UK economy remains stuck in low‑growth, high‑inflation territory.The Political Fragmentation Driving Economic StagnationWith five major parties contesting the upcoming English election and a sixth in Scotland and Wales, the traditional two‑party system has dissolved. The rise of the Greens and Reform UK reflects deep discontent with both Labour and the Conservatives. Voters are increasingly attracted to radical alternatives, hoping for bold policies that could break the current economic impasse.Bond Yields Surge Above 5% – The Numbers Behind the PressureGilt yields have climbed to levels not seen since the 2008 financial crisis, now exceeding 5% and outpacing all other G7 countries. The market’s risk premium reflects two intertwined fears: a potential sharp rise in inflation—exacerbated by the war in Iran—and political uncertainty surrounding the tenure of Keir Starmer as prime minister. Historically, similar spikes preceded crises such as the 1976 sterling debacle and the 2022 “Trussonomics” episode.Current gilt yield: 5%+Highest UK yield since 2008UK yields > all other G7 nationsHow Market Discipline Is Shaping UK Fiscal PolicyBond‑market pressure has forced successive governments—first Rishi Sunak, now Keir Starmer—to raise taxes to historic post‑World‑War‑II levels. Chancellor Rachel Reeves has tweaked borrowing rules to allow more public investment, but the overarching narrative remains one of fiscal restraint. Borrowing stays high, growth remains sluggish, and any attempt to fund large‑scale initiatives (energy subsidies, defence spending, decarbonisation) is weighed against the cost of higher interest payments.What the Next Election Could Mean for the Bond Market‑Government RelationshipIf voters swing toward parties promising to “take back control” from bond dealers, the Treasury may face a credibility test. A government that appears willing to increase borrowing could trigger a fresh surge in yields, tightening financing conditions further. Conversely, a party that embraces market discipline could stabilize yields but risk alienating voters desperate for immediate relief. The likely outcome is a continued balancing act, with bond markets retaining decisive influence over UK fiscal direction for the foreseeable future.

The Shift from Annual Roadmaps to Real-Time Co-CreationArtificial intelligence is advancing at a dizzying clip, forcing enterprises to adapt or risk irrelevance. Salesforce has identified a critical gap in the market: the "last-mile tech" required to fully utilize Large Language Models (LLMs). To bridge this, the customer management software giant is fundamentally restructuring its development cycle, moving away from static annual timelines toward a dynamic, crowdsourced roadmap.Instead of relying on internal speculation, Salesforce is engaging its 18,000 customers in a deep, rotating feedback loop. This strategy involves meeting with key partners as frequently as once a week. By treating customers as a "wellspring of information," Salesforce aims to build products that resonate immediately with real-world use cases rather than theoretical features.Weekly Integration: Direct collaboration with engineering teams to solve immediate problems.Bottom-Up Strategy: Product development is driven by themes like agent context and observability rather than rigid product timelines.Internal Adoption: Salesforce employees are the primary beta testers, ensuring the tools are battle-hardened before release.The Velocity of Innovation: A Data-Driven ApproachThe most significant metric of this strategy is the speed of iteration. Salesforce has shifted from a six-month feedback cycle to a reactive, week-by-week development model. This agility allows the company to push code rapidly and test new features through various gates before a full public release.This approach has accelerated the release of critical AI tools. Salesforce was an early mover in AI agent management software with Agentforce in late 2024 and has since doubled down on voice AI and Slack integrations. The data suggests that this rapid response to customer needs is outpacing competitors who may be bound by slower, more traditional product development cycles.Democratizing Enterprise AI DevelopmentThis crowdsourcing model creates a symbiotic relationship where both Salesforce and its customers gain a competitive edge. By allowing partners like Engine and PenFed to access tools before release, Salesforce enables its clients to stay ahead of the curve.For example, PenFed utilized Agentforce to build a custom IT Service Management (ITSM) workflow, which Salesforce subsequently rolled out to its broader customer base. This demonstrates how user-generated solutions can become enterprise-wide standards. The strategy relies on the premise that customers are the best source for identifying real-world friction points that generic AI models cannot solve.The Future of Co-Creation in Enterprise TechSalesforce's gamble on a customer-driven roadmap carries inherent risks. The model assumes that customers, who are still figuring out the role of AI in their businesses, are the best source for long-term product direction. Furthermore, early beta testing does not guarantee long-term usage or future contract renewals.However, the success of this strategy hinges on adaptability. As Muralidhar Krishnaprasad noted, the company has historically adapted to innovation waves by shifting labor and resources. If Salesforce can maintain this agility and continue to deliver value through direct customer feedback, it may set a new standard for how enterprise software is architected in the age of agentic AI.

The Psychedelic Therapy Trials The US Department of Defense (DoD) is funding two studies into psychedelic therapy for active-duty soldiers with PTSD. The studies, which will involve 186 service personnel, will investigate the use of MDMA-assisted therapy to help soldiers process trauma and reduce symptoms of PTSD. The Research Details The studies will be conducted at the Walter Reed national military medical center and Emory University, with the goal of determining the safety and efficacy of MDMA-assisted therapy for soldiers with PTSD. The therapy involves multiple sessions of MDMA-assisted therapy, with the aim of helping soldiers process trauma and reduce symptoms of PTSD. The Data Analysis The studies will involve a total of 186 service personnel, with 91 military, guard, and reserve personnel set to receive three separate MDMA doses across 10 months at Walter Reed. The studies are expected to cost $4.9m each, with the funding signed off by former president Joe Biden as part of the National Defence Authorization Act in December 2023. The Impact Analysis The use of psychedelic therapy for soldiers with PTSD has the potential to revolutionize the way that the military approaches mental health. According to Rick Doblin, the founding president of the Multidisciplinary Association for Psychedelic Studies (Maps), "Helping people process trauma, whoever they are, is probably better than not." The therapy could also help to reduce the stigma surrounding mental health issues in the military. The Prediction If the studies are successful, MDMA-assisted therapy could become a standard treatment for soldiers with PTSD. The therapy could also have implications for the treatment of PTSD in civilians, and could potentially be used to address other mental health issues. However, there are also concerns about the potential risks of using psychedelic therapy, particularly in an active-duty setting.

The Palantir Manifesto ControversyJust weeks after publishing a manifesto on X that implied some cultures are inferior to others, described by one UK MP as the "ramblings of a supervillain," the US spy tech company Palantir faces growing calls for a ban in Australia. The company, which has significant government contracts in Australia, now claims it is "just a software company" amid mounting public and political backlash.Cultural Statements Spark Global ConcernEarlier this month, Palantir published a manifesto on X, arguing the benefits of American power and stating: "Some cultures have produced vital advances; others remain dysfunctional and regressive." This public pronouncement, combined with concern over Palantir's software being used by ICE immigration enforcement in the United States and the Israeli military, has led to calls in Australia and the UK for governments to cease using Palantir in their operations.Financial Footprint in Australian GovernmentState and federal contracts with Palantir in Australia have reached nearly $80m, with federal investment in the company reportedly more than $160m. Federal agencies including the financial intelligence agency Austrac and the defense department have spent an estimated $60m in contracts with Palantir. Australia's sovereign wealth fund, the Future Fund, holds $100m worth of shares in the company. In Victoria, the prison system has spent nearly $20m on Palantir contracts since 2012, with a current contract valued at $9m and not due to expire until 2028.Government Response and Company DefenseAustralian Greens senator David Shoebridge has called for a "blanket ban on all new contracts with Palantir, pending a comprehensive public audit of their existing Government agreements." In response, a Palantir spokesperson emphasized that the company is "proud its software supports the Australian defense force and other government agencies" and claimed, "We don't collect or monetize data – we simply provide the tools to help customers organize and understand their own information."Regulatory Scrutiny and Future ImplicationsPalantir has identified Australia as a lucrative market for its surveillance software, achieving "protected level" in the Australian Signals Directorate's information security program. However, questions remain about compliance with the Commonwealth supplier code of conduct, which requires suppliers to avoid bringing the federal government into disrepute. With the recent termination of its lobbying relationship with Cmax Advisory and growing public concern, Palantir's future in Australia's government sector faces significant uncertainty as political pressure mounts for greater transparency and accountability.

Saudi PIF Announces End of Funding After the 2026 SeasonThe Public Investment Fund (PIF) confirmed that its financial support for the breakaway LIV Golf league will stop at the close of the 2026 season. In a statement, PIF said the “substantial investment required over a longer term is no longer consistent with the current phase of PIF’s investment strategy.”New LIV Golf Board Targets a Multi‑Partner Investment ModelGene Davis of Pirinate Consulting Group and Jon Zinman of JZ Advisors have been appointed to a newly created board, with Davis serving as chair. Their mandate is to secure long‑term financial partners to replace Saudi capital, while a committee of independent directors will explore strategic alternatives beyond the PIF horizon.Financial Footprint: $5.3 bn Spent Since Launch$1 bn allocated to marquee contracts for players such as Bryson DeChambeau, Brooks Koepka, Phil Mickelson, Cameron Smith and Jon Rahm.$5.3 bn spent by LIV Golf from its 2022 launch; projected to reach $6 bn by year‑end.$30 m prize fund per tournament.Goal for 10 of 13 teams to be profitable this year.Implications for the Global Golf LandscapeThe funding withdrawal reshapes the power balance between LIV Golf and the established PGA Tour. Without PIF backing, LIV must prove its franchise‑team model can attract alternative capital, a challenge that could affect player retention, especially for top signings like DeChambeau and Rahm. The PGA Tour, meanwhile, continues to negotiate pathways for former LIV players, offering limited‑time returns but with strict conditions.Outlook: Funding Strategies and Player RetentionAnalysts expect LIV Golf to pursue a consortium of private investors, media rights deals, and possibly a public‑stock component to sustain operations beyond 2026. Success will hinge on delivering consistent profitability across its teams and maintaining the allure of its $30 m prize pools. If alternative financing falls short, the league may face a talent exodus as contracts expire, potentially accelerating a convergence with the PGA Tour’s ecosystem.

The Riyadh Summit: A Strategic ReassessmentGulf leaders gathered in Riyadh for their first in-person meeting since the outbreak of the US-Israel war with Iran. The agenda extended beyond security protocols to prioritize expediting five major strategic projects designed to deepen economic ties and strengthen collective resilience.Accelerating the GCC Integration AgendaUnder the umbrella of the Gulf Cooperation Council (GCC), these initiatives span transport, energy, water security, and defense. The shift in priority is driven by the realization that these projects are no longer merely economic aspirations but critical security necessities.Unified Gulf Railway Network: A 2,117km network connecting all six member states, designed for passengers and freight at speeds up to 200km/h.Electrical Interconnection Grid: A successful network allowing power sharing, reducing costs and providing emergency backup.Water Interconnection System: A proposed network to share supplies during shortages, addressing vulnerability to Iranian strikes on desalination plants.Oil and Gas Pipeline Integration: Streamlining energy flows and diversifying transport routes to reinforce collective market weight.Joint Ballistic Missile Early Warning System: An integrated defense network using satellite sensors to detect missile launches in real-time.The Economic Case for Regional InterconnectionThe electrical interconnection grid serves as the benchmark for regional integration. Since its full integration in 2014, the system has generated $3bn in economic savings and handled nearly 3,000 emergency support cases through cross-border transfers. This track record proves that shared infrastructure can significantly lower costs and improve reliability.From Sovereignty to Collective ResilienceThe impact of these projects extends beyond infrastructure; it represents a fundamental shift in political calculus. Thomas Bonnie James, a Gulf studies expert at the University of Aberdeen, notes that Iranian strikes have converted these projects from economic aspirations into security necessities. The region is moving toward an approach where "civilian resilience is a collective problem requiring a collective solution."The New Era of Gulf Strategic AutonomyThe geopolitical environment is forcing a faster pace of integration. As James suggests, the difficulty of aligning "six sovereignties" is being overcome by the urgent need for survival. The future outlook suggests a rapid acceleration of these projects, particularly cross-border freight corridors and defense networks, as the GCC seeks to insulate itself from external shocks.

Public Anxiety Peaks as AI Quality Concerns Reach a New High As the U.S. midterm elections loom, voters are increasingly uneasy about artificial intelligence. 57% of registered voters say the risks of AI outweigh the benefits, according to an NBC News poll. Younger adults are even more skeptical: 61% of those under 30 believe more AI will make people worse at creative thinking, per a Pew Research survey. Poll Data Shows Majority Demand Stronger AI Regulation 57% of voters think AI risks outweigh benefits (NBC News). 61% of adults under 30 fear AI will erode creative thinking (Pew). 74% believe the government is not doing enough to regulate AI (Quinnipiac). These figures illustrate a growing political cohort that is ready to back concrete policy measures. Economic and Cultural Costs of AI‑Generated “Slop” Critics label the flood of low‑effort, AI‑generated content as “AI slop”—digital output that appears productive but later requires costly correction. A Goldman Sachs study found AI’s net impact on productivity to be a rounding error, while the Harvard Business Review warns that “workslop” drains human creative labor. Beyond productivity, slop threatens cultural ecosystems: fake music bands on Spotify, AI‑written books crowding Amazon, and inaccurate Google “AI overviews” that generate millions of wrong answers per hour. Legislative Proposal: A 1% Tax on Generative AI Output Mike Pepi proposes a straightforward levy: any company that furnishes or hosts generative AI content would pay an annual ~1% tax on its revenue. The five largest public AI firms—Nvidia, Google, Apple, Microsoft and Meta—collectively hold about $18 trillion in market value, meaning a 1% tax could generate roughly $180 billion each year. Revenue would flow into a publicly controlled fund that distributes grants to cultural institutions, artists, journalists, educators, and research projects—the very sectors whose data train these models. Outlook: From Tax to a Cultural Renaissance? If enacted, the “slop tax” could create a feedback loop: AI firms contribute to the public good, while creators receive resources to produce higher‑quality work. The proposal also offers Democrats a tangible policy win ahead of the midterms, potentially restoring trust among younger voters who feel betrayed by AI’s promises. While broader AI regulation remains fragmented, a targeted levy on the most egregious output may be the pragmatic first step toward a healthier digital ecosystem.