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The Lead Doctors, scientists, and researchers shared new research about ways to tackle cancer at the 2026 American Society of Clinical Oncology (Asco) annual meeting, the world's largest cancer conference. Breakthroughs in Cancer Treatment The event in Chicago, attended by 40,000 health professionals, featured more than 200 sessions and 2,700 poster presentations on this year's theme, “the science and practice of translation: improving cancer outcomes worldwide”. Smart Drugs in Cancer Treatment Researchers have developed a smart drug that stops cancer cells hiding. The experimental tablet, GRWD5769, can help shrink tumours by at least 30% in six of the world’s most common forms of the disease, delegates in Chicago were told. 26 of 83 patients with cervical, bladder, liver, bowel, lung or head and neck cancers who were given GRWD5769 alongside cemiplimab had tumour reductions of at least 30%. 15 had tumour reductions of at least 30%. A Daily Pill for Pancreatic Cancer A pill that doubles survival time in patients with pancreatic cancer was presented at the conference. In a trial of 500 patients, all of whom had pancreatic cancer that had spread, the pill, daraxonrasib, doubled survival time, with fewer side-effects compared with chemotherapy. Patients who took the drug lived substantially longer, for an average of 13.2 months, compared with 6.6 to 6.7 months for patients who had chemotherapy. Safely Skipping Some Treatments Some patients can safely skip some treatments, according to research presented at the conference. A genomic test could pave the way for a new era of personalised medicine, enabling doctors to determine which patients can safely skip chemotherapy. The Optima trial, led by University College London, followed 4,000 patients with newly diagnosed breast cancer in the UK, Norway, Sweden, Australia, New Zealand and Thailand. Those with a low score on the genomic test could be treated safely with hormone therapy alone. The Future of Cancer Treatment Urgent action is required to cope with rising cancer cases. The world faces a cancer workforce crisis, experts said, with a shortage of 100 million staff expected by 2050 when 100,000 people will be being diagnosed every day. A 21% increase in cancer incidence is predicted, according to a report presented at the conference. The rate is set to rise from 165 per 100,000 people in 2025 to 200 per 100,000 in 2050.

The Origins of 'Mogging' Until recently, if someone had said "mog" to me, I probably would have assumed they were talking about the children's book cat created by the late great Judith Kerr. If asked about "mogging" or being "mogged," I would have been completely baffled. But for many members of gen Z and gen Alpha (or anyone who is just a bit too online), the slang term, which means to outdo or outshine others, is everywhere. From Manosphere to Mainstream Mogging's origins are in the manosphere, where it began as a verb derived from the acronym "Amog" (alpha male of the group). In misogynistic forums in the 2010s, to "mog" came to mean to outdo someone in terms of sexual desirability. Mogging has been adopted by "looksmaxxing" influencers such as Braden Peters, known online as Clavicular, who encourage men to try to alter their looks – sometimes in extreme ways – to increase their "sexual market value". Such an influencer might talk of "frame mogging" another person in a photo or video – a variation on mogging that specifically refers to being more muscular. The Evolution of Competitive Language Even now, as the term has begun to be used much more widely, and in a tongue-in-cheek way, it is still typically associated with looks (a friend of mine, for example, was described by her boyfriend's younger siblings as "mogging him" in a photo). But increasingly, mogging can mean besting others at basically anything. The gold medal Olympic figure skater Alysa Liu said in an interview last year that her main competition strategy was "to mog", while a 23-year-old colleague of mine tells me that she and her friends joke about "walk-mogging" when they overtake people on the street. Linguistic Analysis of Modern Slang Tony Thorne, director of the slang and new language archive at King's College London, says a lot of new slang terms "have come recently from the same kind of male-based internet culture", referencing the words "simp" (someone who is excessively attentive), "soy boy" (a derogatory term for a man who is not stereotypically masculine) and "sigma" (someone cool and successful). Not to mention "maxxing," now such an established part of the lexicon that it was tweeted by the US Department of Defense earlier this year. The Cultural Impact of Competitive Slang Thorne thinks it is significant that "mogging" in particular has become fashionable at this time. "What it implies – hyper-competitive, hyper-individualist, aggressive selfishness" has become "mainstream behaviour", he says. Which is why Will Adolphy, a psychotherapist who was himself once an ardent follower of manosphere influencers, has concerns about the word. "Part of me can see how it's a kind of handy, even entertaining word," he says. But the idea of mogging "reinforces this sense that there are certain people that will dominate others based off their physical appearance and status", he says. Psychological Concerns About Competitive Language Dr Emily Sehmer, an NHS child and adolescent psychiatrist, worries too about the "constant sense of competition" that concepts such as mogging help to foster, especially for teenagers, who are developing their socio-emotional skills and typically "have a desire to fit in and to get peer approval". Apart from anything else, she adds, wanting to mog someone is "kind of mean, isn't it?" The Ironical Reappropriation of 'Mogging' "I think people are right to be concerned," about the rise in usage of slang that originates from a toxic subculture, Thorne says – and notes that some of his fellow linguists feel uncomfortable about researching it. But, he adds, "mogging" has moved well beyond its origins, and many people who use it now "tend to understand it and laugh at it, and they use it themselves, but ironically". Certainly, plenty of mogging content on social media now has an irreverence to it: such as the trend of posing for the photo on a rollercoaster in order to "mog" the screaming riders next to you. Making what started as an aggressive concept into something very silly pokes fun at the ridiculousness of the manosphere, my younger colleague explains. She shows me a picture of herself on a recent holiday, standing next to a statue of Napoleon, that she sent to a group chat of her friends. The caption? "I mogged Napoleon!"

The Pond Picasso's Environmental JourneyIn a boggy field in Somerset, Shaun Hancox operates an orange and black excavator, rhythmically removing lumpy clay soil and sculpting it into brown banks. What appears as a scar of bare earth on what was once green pasture will soon transform into a thriving freshwater ecosystem once rain fills the newly created depressions. This is the work of "the Picasso of ponds," a man who has transitioned from shaping golf courses to creating vital wildlife habitats across Britain.The Art and Science of Pond Creation"There's a lot more thought that goes into it than digging a hole," explains Hancox of Creative Wetlands. His background in golf course construction has given him unique insights into water movement and landscape design. "A golf ball rolls very much how water moves. When you're putting in a wildlife pond, you look at the landscape and give your pond the best chance of holding water and doing what it should do." The shapes of his ponds are "almost golf course bunkers but in a more rustic, natural way." At Heal Somerset, a 185-hectare former dairy farm being rewilded, Hancox is digging four new ponds, including one double-bowled pond 30 meters in diameter specifically for great-crested newts.The Decline of Britain's Freshwater HabitatsBritain has lost at least 400,000 ponds over the past century, according to the Freshwater Habitats Trust. A similar number remain, but many are overgrown, degraded, or affected by nutrient pollution. "Everyone realises we're in a sorry state with freshwater and it needs to be addressed," says Hancox. This decline has had devastating consequences for aquatic and semi-aquatic species that depend on these freshwater ecosystems for breeding, feeding, and shelter.Transforming Landscapes for WildlifeThe ponds created by Hancox and his team are specifically designed to maximize their ecological impact. Crucially, these new ponds are not connected to any river system, which can wash nutrient-rich or polluted water into them. Instead, they are charged by clean rainwater or clean groundwater, enabling more delicate aquatic plants to thrive. Within a year of being created, the ponds fill with aquatic life, including damselflies and dragonflies, and provide food and shelter for birds, from moorhens to house martins, who feed on the insects and use the pond-side mud to build nests.The Future of Freshwater ConservationInitiatives like the Newt Conservation Partnership, a coalition of the Freshwater Habitats Trust and the Amphibian and Reptile Conservation Trust, are working to ensure these habitats are maintained long-term. The partnership operates across 70 local authorities in England and ensures that any new pond habitat is maintained for 25 years, with ponds inspected and landowners receiving annual payments to manage them. "It guarantees that they will be suitable for newts in 25 years' time," says Pete Case of the Newt Conservation Partnership. "When it comes to newt conservation, everyone focuses on making a pond, but newts spend two-thirds of their life on land. If you don't get that bit right, they aren't going to do so well." This comprehensive approach to habitat creation and management represents a promising model for future conservation efforts across Britain and beyond.

The Lead: Democracy's Tipping Point in GhanaAccra, Ghana – Ghana has recorded 14 arrests linked to false news and offensive speech in less than 16 months, nearly double the number documented during the previous administration's entire eight-year tenure, according to the Media Foundation for West Africa (MFWA).The rise has triggered a sharp debate in one of West Africa's most stable democracies over whether authorities are simply enforcing long-standing laws in a new digital environment, or edging into a more restrictive approach to public speech.The Political Irony: Mahama's Past WarningsThe controversy carries added political weight because President John Mahama, while in opposition in 2022, warned that using state power to intimidate dissent was a "dangerous blueprint" for democracy.Government Position: Enforcement Not RepressionA senior ruling party official dismissed allegations that the arrests amount to a crackdown."The opposition intentionally sponsors people to insult the President," he told Al Jazeera. "When the law catches up with them, they cry persecution to score cheap political points."He pointed to the case of TikToker Prince Ofori, known as "Fante Comedy", who was arrested last August over alleged threats to President Mahama.Days after his arrest, Ofori appeared at a political rally alongside opposition figures, a development the official said showed how quickly such cases become politicized."They paraded him at an opposition rally," he said.Opposition Response: A Warning Sign for DemocracyOpposition leaders see something more troubling taking shape.Minority leader Alexander Afenyo-Markin has been among the most outspoken critics."The state-sponsored persecution must stop," he told Al Jazeera. "Arresting citizens for words that do not constitute genuine threats is not justice. It is intimidation."He said free speech has limits, but argued that the state is increasingly crossing a line."Excessive use of state power risks undoing Ghana's hard-won democratic gains," he said.Legal Framework: Where is the Line?At the centre of the debate are long-standing provisions in Ghana's Criminal Code and Electronic Communications Act, which authorities say are now being applied to a fast-moving digital landscape.Government supporters argue the increase in arrests reflects the explosion of anonymous and unregulated online content.Critics say the problem is not the laws themselves, but how they are being used.A legal consultant who reviewed recent cases said he counted at least 16 alleged misapplications of Section 208 in the past 18 months, compared with roughly a dozen in the previous eight years."The law has been abused beyond repair," he said. "Repeal is the only remedy."Media Freedom and Blurred BoundariesVeteran journalist Ben Ephson said Ghana needs clearer guidance on where free expression ends and harm begins."The government must properly explain the arrests so people can draw the line between press freedom and responsible journalism," he said.He added that both journalists and state institutions risk overstepping if the rules remain unclear."When you compare the freedom of the media and the rights of the individual, we need to be careful that the media, in trying to do their work, don't trample on people's rights," he said.Global Context: Shrinking Civic SpaceOthers say Ghana's debate mirrors tensions playing out in other democracies.Tegha King of the Universal Peace Federation Ghana said concerns about shrinking civic space are not unique to Ghana."The global civic space must cultivate more free speech, not less," he told Al Jazeera.He said stronger institutions, not more arrests, are needed to manage the pressures of the digital age."There must be independent courts, transparent enforcement, media self-regulation and digital literacy," he said.Civic Awareness and External ConcernSome analysts point to gaps in public understanding of constitutional rights."There is a lack of constitutional education among many Ghanaians," said David Adofo of the African Chamber of Content Producers. "People must know the consequences of their actions before they act, not after."Concerns are also being voiced outside the country."We have had many concerns from diasporans about perceived erosion of press and political freedoms, especially news of blogger arrests," said Nana Kofi Opoku-Agyemang of the NuGhana Expat Center. "Negative news sells fast. The government must be cautious so it does not project a negative image of Ghana in the diasporan community."Government Stance: Existing Laws, New ChallengesOfficials insist there is no coordinated effort to silence dissent.An NDC communicator said the legal framework in question predates the current administration and defended the approach."Ghana's laws, Section 208 of the Criminal Code and Section 76 of the Electronic Communications Act, have been on the books for decades," he said. "What has changed is the sheer volume of reckless, anonymous and sometimes dangerous content on social media. There is no systematic crackdown. There is simply enforcement of existing law."The Path Forward: Breaking the CycleGhana remains one of West Africa's more open democracies, with a competitive political system and active media landscape.But the rise in speech-related arrests has sharpened scrutiny of how far the state can go in policing online expression without undermining the democratic culture that helped define its reputation.The debate is also politically charged because of Mahama's own past warnings.As opposition leader, he described the use of state power against dissent as a "dangerous blueprint." Today, critics say his government faces accusations it once condemned.For Alexander Afenyo-Markin, the moment calls for restraint — and reflection."We should not continue to say that because it happened yesterday, it should happen today and tomorrow. That cycle must end," he said. "President Mahama has an opportunity to leave a legacy of tolerance and free speech. I hope he takes it."

The Rise of Cringe Culture In a TikTok video, Katie Whitney, a 25-year-old with 2.5 million followers, addresses Cynthia Erivo in a way that is described as 'toe-curling' or 'cringe' to watch. This type of content is part of what is known online as CringeTok, a subsection of the internet that deals in content designed to make your toes curl. The Psychology of Cringe Cringe has been identified by some working in mental health as a relatively new form of shame. According to Roger Giner-Sorolla, a professor of social psychology at the University of Kent, cringe is a slang term for the feeling of 'vicarious shame'. This places a person who has done something embarrassing or even morally shameful 'under the dim regard of other people'. Mark Beal, a professor of communications at Rutgers University, describes cringe as 'feeling awkward, feeling embarrassed, feeling uncool'. A key aspect of cringe is a lack of self-awareness. The Impact on Gen Z According to a Yahoo/YouGov poll, the fear of coming across as cringe has stopped more than half of Gen Z from expressing themselves freely online, and 55% of those surveyed said it had stopped them from opening up emotionally. This fear is affecting not only online behavior but also offline interactions, with some people feeling hesitant to participate in activities or express themselves for fear of being ridiculed. The Future of Cringe Culture So can Gen Z get over the fear of cringe? According to Giner-Sorolla, the way to survive is to 'narrow your focus ... have a reference group of people you can be authentic with, and even if other people think your authenticity is cringe, at least you've got your people.' Having connections, having friends, having people you can relate to and share with, is good for the brain. However, not everyone benefits from an audience.

The LeadJeremy Coney recalls the 1986 New Zealand cricket team's historic series win in England, highlighting how they turned England captain Mike Gatting's "Ilford Seconds" insult into motivation. This semi-professional team of teachers, laborers, and even a gravedigger became the first New Zealand side to win a Test series in England.The Underdog SpiritThe New Zealand team, consisting of only three professional players, embraced the "Ilford Seconds" nickname after Gatting's remark that batting against them was like facing a "World XI at one end and Ilford Second XI at the other." Rather than being demoralized, the team ordered T-shirts with "Ilford Seconds" emblazoned on the front and used the insult as motivation throughout the tour.The Team CompositionWith players ranging from teachers and laborers to John Bracewell, a gravedigger from Dunedin, the New Zealand team was a far cry from the professional outfits of their opponents. Despite their unprofessional status on paper, they had already achieved historic victories against Australia at home and away, demonstrating their capabilities.The Turning PointThe series turned on an incident involving England's Phil Edmonds and a distracting wristwatch. After Martin Crowe successfully asked Edmonds to remove his watch, Jeremy Coney playfully asked the umpire to have Edmonds put it back on, claiming the "translucent patch on his wrist was dazzling him." This incident exemplified the team's ability to maintain focus while enjoying the game.The LegacyForty years later, Jeremy Coney reflects on how the team's "bloody hard" and "bloody well" approach to cricket defied expectations. The team's victory remains a significant moment in New Zealand cricket history, showcasing how a group of determined amateurs could overcome professional opposition through heart, skill, and team spirit.

The Final Curtain Call for Hollywood IconsThe 100th anniversary of Marilyn Monroe’s birth has prompted a rerelease of her most serious work, John Huston’s 1961 western The Misfits. This retrospective offers a sombre look at a film that marked the final chapter for its three iconic leads: Monroe, Clark Gable, and Montgomery Clift.The Irony of a 'Misfit' in the American WestAdapted by Arthur Miller, the film tells the story of Roslyn, a woman seeking a quickie divorce in Reno who becomes entangled with three men: an ageing cowboy, a submissive friend, and a reckless bronco rider. The Guardian review notes that despite the title, the characters fit perfectly into their desolate landscape, trapped in a cycle of loneliness and yearning. The film serves as a poignant 'American pastoral' that reflects the disillusionment of the era.The Tragic Destiny of the Wild HorsesThe film's climax, where the characters attempt to capture wild mustangs only to realize they are being sold as pet food, serves as a powerful metaphor. The Guardian describes this as a 'horrible, inglorious and symbolic destiny,' mirroring the characters' own struggles. Monroe’s performance is noted as 'fascinatingly sad,' moving away from her signature breathiness to reveal a raw, authentic vulnerability.Enduring Legacy of a Tragic RomanceAs the film returns to cinemas for the BFI Southbank retrospective, it serves as a reminder of the tragic personal toll on its creators. The Guardian suggests that the film's sombre tone feels more relevant than ever, cementing its status as a masterpiece of American cinema that explores the cost of freedom and the inevitability of loss.

The Plight of Sumatra's Elephants Two elephants, a mother and her calf, were found dead in the Indonesian province of Bengkulu, in an area of 'production forest' in southern Sumatra. The cause of their deaths, along with that of a tiger nearby, is still being investigated. This is not an isolated case, as conservationists report that seven wild elephants have died in Bengkulu since 2018. Habitat Loss and Human-Elephant Conflict The population of Sumatran elephants (Elephas Maximus Sumatranus) around the Seblat district of Bengkulu once thrived but has plummeted due to poaching and deforestation driven by farming and palm oil plantations. The population has decreased from an estimated 100-150 individuals in 2010 to not more than 50 today. Conservation Efforts To protect the remaining elephants, the Bengkulu Natural Resources Conservation Agency (BKSDA) has begun monitoring Seblat using a thermal-imaging drone. The aim is to establish the extent of the elephant population and its habitat, and what should be done to protect it. The agency hopes to reveal the health of the population by identifying the number of calves, which is crucial for the long-term genetic sustainability of the population. The Future of Sumatra's Elephants Conservationists stress that monitoring alone is not enough; the root of the problem – habitat loss and human-elephant conflict – must be addressed. The Indonesian government has taken steps, including revoking the permits of two logging companies. However, more needs to be done to ensure the survival of Sumatra's elephants.

The Escalation of a Local Dispute into National PolicyA local conflict over swimmers and swans at Hampstead Heath has rapidly evolved into a significant policy issue. The incident, which occurred during a period of extreme heat, involved crowds of people ignoring "no swimming" signs in a wildlife pond, disturbing nesting birds and clambering over protected habitats. This behavior was captured on video, sparking widespread public outrage and media condemnation.Government Intervention Over Wildlife DisturbanceIn response to the viral footage and public outcry, Environment ministers have intervened. Over the weekend, they wrote to the City of London Corporation, which oversees the heath, expressing "deeply concerned" views regarding the footage of crowds in the water. This marks a shift from local enforcement to a potential national-level scrutiny of how public spaces are managed during climate emergencies.Key Event: Viral video of revellers in a wildlife pond disturbing nesting birds.Official Response: Environment ministers wrote to the City of London Corporation expressing concern.Public Reaction: Headlines labeled the swimmers "selfish" and "appalling".The High Cost of a Heatwave: Safety and MortalityBeyond the immediate ecological damage, the context of the heatwave highlights a critical human safety crisis. The article notes that the water-related death toll during the recent heatwave was 16, with many victims being teenagers. This statistic underscores the intense pressure on urban populations to find relief from rising temperatures, often leading to risky behavior in open water.The Privatization of Nature and Access to WaterThe author argues that the debate extends beyond simple selfishness. There is a growing sentiment that natural water is being "monetized" and fenced off. While the well-known bathing ponds operate on an honesty system (now with queues and potential costs), the wildlife pond remains off-limits, creating a sense of exclusion. The piece suggests that the public feels a sense of entitlement to natural spaces that are increasingly being restricted or commercialized.Future Outlook: Designated Spaces and EducationAs climate change drives temperatures higher, the demand for accessible swimming spots will only increase. The article predicts a future where the focus must shift from punitive fines to education and infrastructure. There is a call for clearer signage explaining the risks and benefits of swimming, as well as the creation of more designated swimming locations to manage demand and protect wildlife.